In conclusion, this study shows an overall appropriate use of ADs in acutely hospitalized older people in internal medicine and geriatric wards from 2010 to 2017, but still some critical aspects were highlighted: an increasing number of patients prescribed ADs despite their history of falls, the frequent combinations between ADs and drugs acting on CNS and the concomitant use of other drugs that can cause potential drug-drug interactions. The hospital setting should represent an important opportunity to improve the quality of drug prescription for frail, multimorbid and polytreated older patients. In our previous studies we pointed out that hospitalization did fail in this goal [7–10]. With reference to ADs, even if the overall use was often mainly appropriate, physicians should improve their knowledge on the risks related to potential DDI and on the concomitant use of drugs that may increase the risk of falls in the elderly, in order to avoid harmful adverse events for patients and unnecessary direct and indirect costs for National Health Service.

Prevalence of use and appropriateness of antidepressants prescription in acutely hospitalized elderly patients

Purrello F.;Di Pino A.;Piro S.;Castellino P.;Zanoli L.;Pignataro S.;Gennaro A.;Blanco J.;Malatino L.;Terranova V.;Di Marca S.;Di Quattro R.;
2019

Abstract

In conclusion, this study shows an overall appropriate use of ADs in acutely hospitalized older people in internal medicine and geriatric wards from 2010 to 2017, but still some critical aspects were highlighted: an increasing number of patients prescribed ADs despite their history of falls, the frequent combinations between ADs and drugs acting on CNS and the concomitant use of other drugs that can cause potential drug-drug interactions. The hospital setting should represent an important opportunity to improve the quality of drug prescription for frail, multimorbid and polytreated older patients. In our previous studies we pointed out that hospitalization did fail in this goal [7–10]. With reference to ADs, even if the overall use was often mainly appropriate, physicians should improve their knowledge on the risks related to potential DDI and on the concomitant use of drugs that may increase the risk of falls in the elderly, in order to avoid harmful adverse events for patients and unnecessary direct and indirect costs for National Health Service.
depression, hospitalized patients, drugs
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11769/370683
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