Among polychlorinated biphenyls (PCBs), dioxin-like PCBs (DL-PCBs) are of the most concern for human health. In this study, the levels of 12 DL-PCBs congeners were measured in 125 fish samples of the Caspian Sea, Iran. Five fish species (Oncorhynchus mykiss, Vimba vimba, Cyprinus carpio, Rutilus frisii kutum and Chelon saliens) were collected from 5 coastal cities of the Caspian Sea (25 samples per each city). Duncan's multi-scope test was used to compare the mean of DL-PCBs in different fish species and different cities. Probabilistic risk of exposure to DL-PCBs and sensitivity analysis were assessed using Monte Carlo simulation approach. The average (standard deviation) of DL-PCBs in fish samples ranged from 232 (16) to 1156 (14) pg/g lipids. The total maximum concentration was detected in Cyprinus carpio from Bandar Anzali, the minimum in Vimba vimba from Chalos. In all samples, non-carcinogenic risk of exposure to DL-PCBs was in safe level (Hazard Quotient < 1). In contrast, the lifetime cancer risk estimated for Bandar Anzali, Bandar Torkaman, and Rasht exceeded the threshold value of 1 × 10-6 suggested by United States Environmental Protection Agency. Sensitivity analysis indicated that the concentration of DL-PCBs and exposure frequency were the most effective parameters in increasing carcinogenic risk.
|Titolo:||Comparing dioxin-like polychlorinated biphenyls in most consumed fish species of the Caspian Sea|
OLIVERI CONTI, GEA MARZIA [Writing – Review & Editing]
|Data di pubblicazione:||2019|
|Appare nelle tipologie:||1.1 Articolo in rivista|