Clinical nerve conduction studies (NCS) are often used as a secondary outcome measure in therapeutic trials, but show a high degree of inter-trial variability even when technical factors known to affect the recorded responses are minimised. This raises the intriguing possibility that some of the observed variability may reflect true changes in nerve activity.

Nerve Conduction Studies as a Measure of Disease Progression: Objectivity or Illusion?

Lanza G.;
2017

Abstract

Clinical nerve conduction studies (NCS) are often used as a secondary outcome measure in therapeutic trials, but show a high degree of inter-trial variability even when technical factors known to affect the recorded responses are minimised. This raises the intriguing possibility that some of the observed variability may reflect true changes in nerve activity.
Nerve conduction studies; nerve excitability; reproducibility; serial measurements; technical variability; Adult; Electrophysiology; Female; Humans; Male; Neural Conduction; Reproducibility of Results
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/20.500.11769/372305
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