Blood homocysteine levels are increased in hepatocellular carcinoma patients with portal vein thrombosis. A single centre retrospective cohort study

Malaguarnera, M.; Catania, V. E.; Borzi, A. M.; Malaguarnera, S.; Madeddu, R.; Bertino, G.; Latteri, S.

doi:10.1016/j.ijso.2018.11.001

Background: Portal vein thrombosis (PVT) is reported in 10–40% of hepatocellular carcinoma (HCC) patients. The development of PVT is a multifactorial process, resulting from a reduction in portal blood flow and hypercoagulability. Methods: We evaluated 44 HCC patients with PVT, 50 HCC patients without PVT and 50 healthy subjects. Homocysteine (Hcy), Vitamin B6, Vitamin B12 and folate were measured. Results: Hcy in HCC patients with PVT is significant higher than the patients without PVT and controls subjects. Conclusion: Total Hcy is a sensitive marker of PVT in patients with HCC.

Titolo:	Blood homocysteine levels are increased in hepatocellular carcinoma patients with portal vein thrombosis. A single centre retrospective cohort study
Autori interni:	MALAGUARNERA, MICHELE CATANIA, Vito Emanuele BORZI', ANTONIO MARIA Malaguarnera S. Madeddu R. BERTINO, Gaetano LATTERI, FRANCESCO SAVERIO mostra contributor esterni nascondi contributor esterni
Data di pubblicazione:	2018
Rivista:	INTERNATIONAL JOURNAL OF SURGERY OPEN
Handle:	http://hdl.handle.net/20.500.11769/377459
Appare nelle tipologie:	1.1 Articolo in rivista

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http://hdl.handle.net/20.500.11769/377459

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