The missing link: Ab initio calculations carried out on a series of terminally blocked polyalanines AcAla nNH 2 provide a detailed picture on stabilities of peptide secondary structures. Among them is the polyproline II helical structure (see picture), found ubiquitously in polyalanine-rich peptides, whose stability is still poorly understood theoretically.
On the Stability of Polyalanine Secondary Structures: The Role of the Polyproline II Helix
LANZA, GIUSEPPE;CHIACCHIO, Ugo;MOTTA, Santo;
2011-01-01
Abstract
The missing link: Ab initio calculations carried out on a series of terminally blocked polyalanines AcAla nNH 2 provide a detailed picture on stabilities of peptide secondary structures. Among them is the polyproline II helical structure (see picture), found ubiquitously in polyalanine-rich peptides, whose stability is still poorly understood theoretically.File in questo prodotto:
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