A 71-year-old woman presented with a rare case of malignant fibrous histiocytoma (MFH) associated with recurrent meningothelial meningioma. The neuroimaging findings were consistent with a diagnosis of recurrent meningioma. Surgical removal was performed. Histological and immunohistochemical examinations detected meningothelial and MFH tumor components. The MFH component showed diffuse 3+ staining for epidermal growth factor receptor protein, predominantly located on the cell membrane and to a lesser extent within the cytoplasm. However, a fluorescein isothiocyanate analysis detected no amplification of epidermal growth factor receptor gene.
|Titolo:||Epidermal growth factor receptor overexpressed malignant fibrous histiocytoma associated with recurrent meningothelial meningioma|
|Data di pubblicazione:||2009|
|Citazione:||Epidermal growth factor receptor overexpressed malignant fibrous histiocytoma associated with recurrent meningothelial meningioma / CALTABIANO R; PARISI G; ALBANESE V; LANZAFAME S. - In: NEUROLOGIA MEDICO-CHIRURGICA. - ISSN 0470-8105. - 49(11)(2009), pp. 523-527.|
|Appare nelle tipologie:||1.1 Articolo in rivista|