Sarcoidosis is a chronic inflammatory multisystem disease of unknown aetiology.IFN-alfa is an immunomodulatory cytokine, currently used with ribavirin in thetreatment of chronic hepatitis C infection. Due to its effects on the immunesystem, IFN-? may lead to the induction or exacerbation of autoimmune diseases,such as systemic lupus erythematosus, rheumatoid arthritis and sarcoidosis. Wereport on a 37-year-old man, presenting with sarcoidosis during a six-monthcourse of PEG-IFN alfa-2a and ribavirin for chronic hepatitis C virus genotype 3 infection.
Un caso di sarcoidosi associata al trattamento con peg-ifn α-2a e ribavirina in un paziente affetto da epatite cronica hcv correlata: Caso clinico e revisione della letteratura [Development of sarcoidosis during treatment for chronic hepatitis C with pegylated interferon alfa-2a and ribavirin: case report and literature review]
CACOPARDO, Bruno Santi;Nunnari G.
2013-01-01
Abstract
Sarcoidosis is a chronic inflammatory multisystem disease of unknown aetiology.IFN-alfa is an immunomodulatory cytokine, currently used with ribavirin in thetreatment of chronic hepatitis C infection. Due to its effects on the immunesystem, IFN-? may lead to the induction or exacerbation of autoimmune diseases,such as systemic lupus erythematosus, rheumatoid arthritis and sarcoidosis. Wereport on a 37-year-old man, presenting with sarcoidosis during a six-monthcourse of PEG-IFN alfa-2a and ribavirin for chronic hepatitis C virus genotype 3 infection.File in questo prodotto:
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