The antiphospholipid syndrome (APS) is an autoimmune thrombophilic condition characterized by the presence in blood of antibodies that recognize phospholipid-binding proteins. The clinical manifestation of APS include arterial and venous thromboembolic events and/or obstetric complications (especially recurrent fetal losses). The antiphospholipid antibodies (aPLA) associated with the disease include the lupus anticoagulant (LA), anti-cardiolipin (a-CL), and anti-β2glycoprotein-I (a-β2GP-I). APS and aPLA can occur in isolation (primary) or in association with systemic lupus erythematosus (secondary). Keywords
The Antiphospholipid Syndrome
CACCIOLA, Rossella Rosaria;CACCIOLA, Emma
2015-01-01
Abstract
The antiphospholipid syndrome (APS) is an autoimmune thrombophilic condition characterized by the presence in blood of antibodies that recognize phospholipid-binding proteins. The clinical manifestation of APS include arterial and venous thromboembolic events and/or obstetric complications (especially recurrent fetal losses). The antiphospholipid antibodies (aPLA) associated with the disease include the lupus anticoagulant (LA), anti-cardiolipin (a-CL), and anti-β2glycoprotein-I (a-β2GP-I). APS and aPLA can occur in isolation (primary) or in association with systemic lupus erythematosus (secondary). KeywordsFile in questo prodotto:
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