The 5-HT7 receptors (5-HT7Rs) are the most recent classified members of the serotonin family. Characterized in 1993, they belong to the G protein-coupled receptor family. Since their discovery, they have beery the subject of intense research due to their widespread distribution in the brain, suggestive of multiple central roles. The focus of this review is to discuss the literature concerning recent advances on 5-HT7Rs and their ligands
5-HT7 receptor ligands: recent developments and potential therapeutic applications
PITTALA', Valeria;MODICA, Maria Nunziata;SALERNO, Loredana;SIRACUSA, Maria Angela;ROMEO, Giuseppe
2007-01-01
Abstract
The 5-HT7 receptors (5-HT7Rs) are the most recent classified members of the serotonin family. Characterized in 1993, they belong to the G protein-coupled receptor family. Since their discovery, they have beery the subject of intense research due to their widespread distribution in the brain, suggestive of multiple central roles. The focus of this review is to discuss the literature concerning recent advances on 5-HT7Rs and their ligandsFile in questo prodotto:
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