Spectrum of gross motor and cognitive functions in children with cerebral palsy: Gender differences

Background: Multiple differences between males and females are reported both in physiologicaland pathophysiological conditions.Aims: To test the hypothesis that gender could influence the motor and cognitive developmentin children with cerebral palsy (CP).Methods: Prospective, cross-sectional. One hundred seventy one children with CP (98 malesand 73 females) were evaluated for motor (Gross Motor Function Measure, Gross MotorFunction Classification System) and cognitive (Bayley II, Wechsler Scales) functions. Eightyfourof them were assessed before and other eighty-seven children after 4 years of age.Results: No gender-related differences were observed in children with diplegia or quadriplegia,both for motor and cognitive functions. On the contrary, females with hemiplegiascored significantly better (P < 0.01) in cognitive functions and in the dimension D(standing) of the Gross Motor Function Measure, under the age of 4 years. These differenceswere not observed after this age.Conclusions: In this study we point out that gender might influence differently the psychomotordevelopment of children with hemiplegia and of those with a more severe clinicalinvolvement as diplegia and quadriplegia.