Previous studies have demonstrated that a soluble urokinase-type plasminogen activator receptor (suPAR) plays an essential function in leukocytes and endothelial homeostasis and, therefore, in the development of coronary heart disease (CHD) and periodontitis. The aim of this study was to analyze the impact of gingival health, periodontitis and CHD on suPAR levels in plasma and saliva and to evaluate suPAR as a biomarker of periodontitis and CHD.

Independent impact of periodontitis and cardiovascular disease on elevated soluble urokinase-type plasminogen activator receptor (suPAR) levels

Isola, Gaetano
Primo
Writing – Review & Editing
;
Leonardi, Rosalia
Ultimo
Conceptualization
2020-01-01

Abstract

Previous studies have demonstrated that a soluble urokinase-type plasminogen activator receptor (suPAR) plays an essential function in leukocytes and endothelial homeostasis and, therefore, in the development of coronary heart disease (CHD) and periodontitis. The aim of this study was to analyze the impact of gingival health, periodontitis and CHD on suPAR levels in plasma and saliva and to evaluate suPAR as a biomarker of periodontitis and CHD.
2020
C-Reactive Protein
Cardiovascular diseases
Periodontitis
Plasminogen Activators
Saliva
Serum
File in questo prodotto:
File Dimensione Formato  
Isola et al JOP 2020 suPAR.pdf

solo utenti autorizzati

Tipologia: Versione Editoriale (PDF)
Dimensione 608.28 kB
Formato Adobe PDF
608.28 kB Adobe PDF   Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11769/484145
Citazioni
  • ???jsp.display-item.citation.pmc??? 54
  • Scopus 83
  • ???jsp.display-item.citation.isi??? 71
social impact