High dose intravenous glucocorticoid (ivGC) therapy is the first line treatment in moderate to severe Graves' ophthalmopathy (GO) and is associated with a clinical response rate ranging from 50% to 80%. Recently, a positive correlation between total cholesterol and low-density lipoproteins cholesterol (LDLc) with GO presentation and activity has been described.

Evidence That Baseline Levels of Low-Density Lipoproteins Cholesterol Affect the Clinical Response of Graves' Ophthalmopathy to Parenteral Corticosteroids

Naselli, Adriano;Moretti, Diletta;Regalbuto, Concetto;Lo Giudice, Fabrizio;Frasca, Francesco;Belfiore, Antonino;Le Moli, Rosario
2020-01-01

Abstract

High dose intravenous glucocorticoid (ivGC) therapy is the first line treatment in moderate to severe Graves' ophthalmopathy (GO) and is associated with a clinical response rate ranging from 50% to 80%. Recently, a positive correlation between total cholesterol and low-density lipoproteins cholesterol (LDLc) with GO presentation and activity has been described.
2020
Graves’ disease
Graves’ ophthalmopathy
cholesterol
low-density lipoprotein cholesterol
parenteral corticosteroids
File in questo prodotto:
File Dimensione Formato  
fendo-11-609895.pdf

accesso aperto

Descrizione: Articolo principale
Tipologia: Versione Editoriale (PDF)
Dimensione 2.95 MB
Formato Adobe PDF
2.95 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11769/495047
Citazioni
  • ???jsp.display-item.citation.pmc??? 9
  • Scopus 27
  • ???jsp.display-item.citation.isi??? 19
social impact