Abstract Evidence suggests that the JAK2 V617F mutationis associated with an increased risk of first thrombosisin patients with essential thrombocythemia (ET). Whetherthis mutation is also a risk factor for recurrent thrombosis iscurrently unknown. To investigate the impact of the JAK2V617F mutation on the risk of recurrent thrombosis inpatients with ET, we carried out a multicentre retrospectivecohort study. We recruited 143 patients with previousarterial (64.4%) or venous major thrombosis (34.8%) orboth (0.8%); 98 of them (68.5%) carried the mutation
Titolo: | Increased risk of recurrent thrombosis in patients with essential thrombocythemia carrying the homozygous JAK2 V617F mutation | |
Autori interni: | ||
Data di pubblicazione: | 2010 | |
Rivista: | ||
Handle: | http://hdl.handle.net/20.500.11769/53083 | |
Appare nelle tipologie: | 1.1 Articolo in rivista |
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