Increased risk of recurrent thrombosis in patients with essential thrombocythemia carrying the homozygous JAK2 V617F mutation

De Stefano, V; Za, T; Rossi, E; Vannucchi, Am; Ruggeri, M; Elli, E; Micò, C; Tieghi, A; Cacciola, Rr; Santoro, C; Vianelli, N; Guglielmelli, P; Pieri, L; Scognamiglio, F; Cacciola, E; Rodeghiero, F; Pogliani, Em; Finazzi, G; Gugliotta, L; Leone, G; Barbui, T

doi:10.1007/s00277-009-0788-5

Abstract Evidence suggests that the JAK2 V617F mutationis associated with an increased risk of first thrombosisin patients with essential thrombocythemia (ET). Whetherthis mutation is also a risk factor for recurrent thrombosis iscurrently unknown. To investigate the impact of the JAK2V617F mutation on the risk of recurrent thrombosis inpatients with ET, we carried out a multicentre retrospectivecohort study. We recruited 143 patients with previousarterial (64.4%) or venous major thrombosis (34.8%) orboth (0.8%); 98 of them (68.5%) carried the mutation

Increased risk of recurrent thrombosis in patients with essential thrombocythemia carrying the homozygous JAK2 V7ì617F mutation / DE STEFANO, V; Za, T; Rossi, E; Vannucchi, Am; Ruggeri, M; Elli, E; Micò, C; Tieghi, A; Cacciola, Rr; Santoro, C; Vianelli, N; Guglielmelli, P; Pieri, L; Scognamiglio, F; Cacciola, Emma; Rodeghiero, F; Pogliani, Em; Finazzi, G; Gugliotta, L; Leone, G; Barbui, T; GIMEMA CHRONIC, Myeloproliferative; NEOPLASMS WORKING, Party. - In: ANNALS OF HEMATOLOGY. - ISSN 0939-5555. - 89(2)(2010), pp. 141-146.

Titolo:	Increased risk of recurrent thrombosis in patients with essential thrombocythemia carrying the homozygous JAK2 V617F mutation
Autori interni:	DE STEFANO V ZA T ROSSI E VANNUCCHI AM RUGGERI M ELLI E MICÒ C TIEGHI A CACCIOLA, Rossella Rosaria SANTORO C VIANELLI N GUGLIELMELLI P PIERI L SCOGNAMIGLIO F CACCIOLA, Emma RODEGHIERO F POGLIANI EM FINAZZI G GUGLIOTTA L LEONE G BARBUI T mostra contributor esterni nascondi contributor esterni
Data di pubblicazione:	2010
Rivista:	ANNALS OF HEMATOLOGY
Citazione:	Increased risk of recurrent thrombosis in patients with essential thrombocythemia carrying the homozygous JAK2 V7ì617F mutation / DE STEFANO, V; Za, T; Rossi, E; Vannucchi, Am; Ruggeri, M; Elli, E; Micò, C; Tieghi, A; Cacciola, Rr; Santoro, C; Vianelli, N; Guglielmelli, P; Pieri, L; Scognamiglio, F; Cacciola, Emma; Rodeghiero, F; Pogliani, Em; Finazzi, G; Gugliotta, L; Leone, G; Barbui, T; GIMEMA CHRONIC, Myeloproliferative; NEOPLASMS WORKING, Party. - In: ANNALS OF HEMATOLOGY. - ISSN 0939-5555. - 89(2)(2010), pp. 141-146.
Handle:	http://hdl.handle.net/20.500.11769/53083
Appare nelle tipologie:	1.1 Articolo in rivista

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