The elderly is characterized by a gradual decline in body function, which represents the clinical situation called "frailty". Prefrailty is the intermediate stage between frailty and the robust condition. L-carnitine (LC) plays an important role in energy production from long-chain fatty acids in mitochondria and its serum level is lower in prefrail and frail subjects.

Acetyl-L-carnitine can slow the progression from prefrailty to frailty in older subjects. A randomized interventional clinical trial

Malaguarnera, Giulia;Catania, Vito Emanuele;Bertino, Gaetano
Conceptualization
;
Bonfiglio, Claudia;Malaguarnera, Michele
2022-01-01

Abstract

The elderly is characterized by a gradual decline in body function, which represents the clinical situation called "frailty". Prefrailty is the intermediate stage between frailty and the robust condition. L-carnitine (LC) plays an important role in energy production from long-chain fatty acids in mitochondria and its serum level is lower in prefrail and frail subjects.
Acetyl-L-Carnitine
Carnitine
Frailty
Prefrailty.
aging
cognitive impairment
elderly
motor impairment
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11769/542762
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