Spontaneous Bone Regeneration after Enucleation of Mandibular Cysts: Retrospective Analysis of the Volumetric Increase with a Full-3D Measurement Protocol

The goal of surgical treatment of mandibular cysts is their eradication. This result can be achieved by ensuring minimum risk of morbidity, while preserving the integrity of the bone structure and the functionality of the inferior alveolar nerve. The generation of bone defects after enucleation has always posed the dilemma of using filler materials or not. The aim of this study is to evaluate the degree of spontaneous bone regeneration, in terms of volume, in patients undergoing enucleation of mandibular cysts, measuring the real 3D volume of the cystic residual cavities. We included in our study 15 patients with mandibular cysts, treated from January 2018 to June 2020 at the Policlinico-Vittorio Emanuele and Policlinico-San Marco hospital of Catania and evaluated preoperatively (T0), 6 months after surgery (T1), and 12 months after surgery (T2). The results showed that after 6 months, independent of the initial volume of the cyst, around 90% of the cavity was filled with new generated bone. In conclusion, we believe that the full-3D measurement protocol can help us to understand the timing and modality of bone restoration after mandibular cyst enucleation