An Effective Methodology for Movement Evaluation in Patients with Parkinson’s Disease

Analyzing pathological movements can substantially help neurologists in the diagnosis and treatment improvement for patients with Parkinson’s disease (PD). A linkage between the intensity and characteristics of moving and walking disorders and the stage and types of PD can be actually established. The main aim of this study is to develop an effective methodology that allows to evaluate, in real time and / or in deferred time, movements and posture of PD patients in their usual living environments. For this purpose, a wearable suit with Inertial Measurement Unit (IMU) sensors was designed; it has made it possible to acquire linear and angular signals of displacement, velocity and acceleration of the most relevant body points of the patients. The filtered and integrated signals were then used to animate a human parametric multibody model that virtually reproduces in real time and / or in deferred patient’s movements and posture. Serving as the patient's “avatar”, the multibody model enables the neurologist to carry out an accurate assessment of the patient’s movements and posture (freezing, festination, postural balance) as well as to measure disease progression and response to interventions. If compared to traditional 3D video-based motion analysis systems, the proposed method has the advantage of providing a more accurately measurable patients movements analysis and comparison performed in their usual living environments in real-world conditions.