The transient intermediates involved in the photochemistry of naphazoline (NP, 2-[1-naphthylmethyl]imidazoline) have been examined using laser hash photolysis techniques. The photoreactivity of the drug is characterized by a photoionization process occurring through a mixture of mono- and biphotonic pathways. An intramolecular electron transfer involving both the imidazoline and the naphthalene moieties leads to the formation of nitrogen-centered radicals. The generation of singlet oxygen from the lowest excited triplet state of NP is also observed. The results obtained demonstrate the potential for NP to act as a both a type I and type II photosensitizer. RI Sortino, Salvatore/E-4684-2011
Photogeneration of hydrated electrons, nitrogen-centered radicals and singlet oxygen from naphazoline: A laser flash photolysis study
SORTINO, Salvatore;
1999-01-01
Abstract
The transient intermediates involved in the photochemistry of naphazoline (NP, 2-[1-naphthylmethyl]imidazoline) have been examined using laser hash photolysis techniques. The photoreactivity of the drug is characterized by a photoionization process occurring through a mixture of mono- and biphotonic pathways. An intramolecular electron transfer involving both the imidazoline and the naphthalene moieties leads to the formation of nitrogen-centered radicals. The generation of singlet oxygen from the lowest excited triplet state of NP is also observed. The results obtained demonstrate the potential for NP to act as a both a type I and type II photosensitizer. RI Sortino, Salvatore/E-4684-2011I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
