INTERFERENZA DELLA CLINDAMICINA SULL’INFEZIONE CUTANEA DEL CONIGLIO DOVUTA A FILI DI SUTURA INFETTATI CON S. EPIDERMIDIS PRODUTTORE DI SLIME

The Authors have carried out an experimental study to evaluate the interference of sub.inhibitory concentrations of clindamycin on the adherence of slim e producing S.epidermidis to surgical nets and its ability to infect rabbits. (0 rabbits divided into 4 groups (A,B,C, and D), underwent sham operation of the abdominal zone and were sewn up with steril nets, infected netis and sub-MIC of clindamycin equal to 1/8 MIC, respectively. The results obtained stressed a different survival rate 12 days after operation: 95% in group A, 35% in group B; 100% in gruop C and 95% in group D. This data were confirmed by the results obtained using MES ( Cambridge Stereoscan 150 KM2). from our research an excellent clindamycin inhibitory activity on the pathogenicity of slime producing staphilococci emerged.