A female patient with chronic myelocytic leukemia (CML) in chronic phase after busulfan and interferon treatment had four different cell lines in her bone marrow. In addition to cells with a normal karyotype there were cells with the Philadelphia chromosome (Ph1), cells with trisomy 8 and a Ph1, and cells with trisomy 8 as the sole anomaly. Copyright © 1992 Wiley‐Liss, Inc., A Wiley Company

Trisomy 8 in philadelphia chromosome (ph1)‐negative cells in the course of ph1‐positive chronic myelocytic leukemia

Milone G.;Di Raimondo F.;
1992-01-01

Abstract

A female patient with chronic myelocytic leukemia (CML) in chronic phase after busulfan and interferon treatment had four different cell lines in her bone marrow. In addition to cells with a normal karyotype there were cells with the Philadelphia chromosome (Ph1), cells with trisomy 8 and a Ph1, and cells with trisomy 8 as the sole anomaly. Copyright © 1992 Wiley‐Liss, Inc., A Wiley Company
1992
Aged; Busulfan; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Female; Humans; Interferon Type I; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mosaicism; Recombinant Proteins; Translocation, Genetic; Chromosomes, Human, Pair 8; Trisomy
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11769/628055
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