The disease of Charcot-Marie-Tooth is a degenerative disease of the nervous system, it strikes one or more neuronals systems and can involve neurons of the central and peripheral motor system, so it can interest Gall and Burdach faces or the spine-cerebral faces. From the histological point of view, we can observe an atrophy of the nervous cells and primary degeneration of the fibers subject to the process of continuous demyelinization distribution, the thesa mieliniches got reduced are inflated and are fragmented into lumps. C h a r c o t - M a r i e - Tooth is due to the alteration of one or more geniuses that give way to the formation of the assone and the genesis of the myelin, whose synthetic deficit involves the reduction of the speed of nervous management. Two principal forms of the disease of Charcot-Marie-Tooth have been described: Form demyelinized and Form assonale. In the demyelinization and in the assonale forms the nervous fibers striked are those longer which are destined to the muscles of the feet, of the legs, and of the hands but also the sensorial fibers run into degeneration and death.
Audiology reliefs in the disease of Charcot-Marie-Tooth
SERRA, Agostino;GRILLO, Calogero;MAIOLINO, Luigi;COCUZZA, SALVATORE GIUSEPPE;
2008-01-01
Abstract
The disease of Charcot-Marie-Tooth is a degenerative disease of the nervous system, it strikes one or more neuronals systems and can involve neurons of the central and peripheral motor system, so it can interest Gall and Burdach faces or the spine-cerebral faces. From the histological point of view, we can observe an atrophy of the nervous cells and primary degeneration of the fibers subject to the process of continuous demyelinization distribution, the thesa mieliniches got reduced are inflated and are fragmented into lumps. C h a r c o t - M a r i e - Tooth is due to the alteration of one or more geniuses that give way to the formation of the assone and the genesis of the myelin, whose synthetic deficit involves the reduction of the speed of nervous management. Two principal forms of the disease of Charcot-Marie-Tooth have been described: Form demyelinized and Form assonale. In the demyelinization and in the assonale forms the nervous fibers striked are those longer which are destined to the muscles of the feet, of the legs, and of the hands but also the sensorial fibers run into degeneration and death.File | Dimensione | Formato | |
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