A case of solitary osteolytic lesion in the parietal bone in an otherwise asymptomatic patient is reported. Skull radiographs showed a radiolucent lesion with well-defined margins without sclerotic reaction, CT scan demonstrated a mass that markedly enhanced extending from the epidural to the subcutaneous space of the parietal region. The patient underwent surgery and tumor was completely excised. Pathological examination showed tumor to be a plasmacytoma synthesizing κ chains. Postoperatively the patient received radiotherapy. Four years after treatment there was no sign of local recurrence on CT scan and of progression to multiple myloma on clinical and laboratory studies. Our recommended treatment is that of a complete surgical excision followed by radiation to dose levels of 45-50 Gy. The patients should be followed carefully because of either local recurrence or possible progression to multiple myeloma. Radiotherapy and chemotherapy should started when signs of progression or other significant disease manifestations occur.
Parietal bone non-secreting solitary myeloma (plasmacytoma) with spread to the epidural space and scalp. Case report
Magro G.;Albanese V.
1995-01-01
Abstract
A case of solitary osteolytic lesion in the parietal bone in an otherwise asymptomatic patient is reported. Skull radiographs showed a radiolucent lesion with well-defined margins without sclerotic reaction, CT scan demonstrated a mass that markedly enhanced extending from the epidural to the subcutaneous space of the parietal region. The patient underwent surgery and tumor was completely excised. Pathological examination showed tumor to be a plasmacytoma synthesizing κ chains. Postoperatively the patient received radiotherapy. Four years after treatment there was no sign of local recurrence on CT scan and of progression to multiple myloma on clinical and laboratory studies. Our recommended treatment is that of a complete surgical excision followed by radiation to dose levels of 45-50 Gy. The patients should be followed carefully because of either local recurrence or possible progression to multiple myeloma. Radiotherapy and chemotherapy should started when signs of progression or other significant disease manifestations occur.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
