Sickle cell disease (SCD) is an increasingly relevant condition in Italy due to rising immigration from high-prevalence regions. Early diagnosis through newborn screening and comprehensive management - including hydroxyurea, antibiotic prophylaxis, transfusions and bone marrow transplantation - are essential to improve outcomes. The article covers key clinical issues, from early detection and vaccination to innovative treatments like gene therapy. Its goal is to provide paediatricians with practical guidance for recognizing and treating SCD in children effectively.
Facciamo il punto sull’anemia falciforme [SHEDDING LIGHT ON SICKLE CELL DISEASE]
Cuzzubbo D.;Russo G.
Ultimo
2025-01-01
Abstract
Sickle cell disease (SCD) is an increasingly relevant condition in Italy due to rising immigration from high-prevalence regions. Early diagnosis through newborn screening and comprehensive management - including hydroxyurea, antibiotic prophylaxis, transfusions and bone marrow transplantation - are essential to improve outcomes. The article covers key clinical issues, from early detection and vaccination to innovative treatments like gene therapy. Its goal is to provide paediatricians with practical guidance for recognizing and treating SCD in children effectively.File in questo prodotto:
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Tessitore SCD MeB_2505.pdf
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