: The mechanism of molecular passage through nuclear pore complexes (NPCs) remains debated between passive diffusion and constrained transport. Integrating single-particle tracking, cargo-centric ensemble assays, and fluctuation analyses reveals that productive transport events are rapid, spatially confined, and biased, supporting a convergent phenomenology that provides an integrated view of NPC transport.
Toward an integrated view of nuclear pore transport
Lanzano' L.Primo
;
2026-01-01
Abstract
: The mechanism of molecular passage through nuclear pore complexes (NPCs) remains debated between passive diffusion and constrained transport. Integrating single-particle tracking, cargo-centric ensemble assays, and fluctuation analyses reveals that productive transport events are rapid, spatially confined, and biased, supporting a convergent phenomenology that provides an integrated view of NPC transport.File in questo prodotto:
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