This preliminary study evaluated the use of the Platelia Candida antigen kit for the diagnosis of invasive candidosis in 70 of 184 pre-term infants admitted to a neonatal intensive care unit between March 2004 and March 2006. The frequency of confirmed candidaemia was 6.5%. The sensitivity and specificity of the assay were 94.4% and 94.2%, respectively, with a positive predictive value of 85% and a negative predictive value of 98%. These results suggest that the inclusion of regular serological surveillance for mannanaemia in some pre-term infants would complement blood cultures for the early detection of candidosis.
|Titolo:||Exsperience with the Platelia Candida ELISA for the diagnosis of invasive candidosis in neonatal patients|
|Autori interni:||OLIVERI, Salvatore|
|Data di pubblicazione:||2008|
|Rivista:||CLINICAL MICROBIOLOGY AND INFECTION|
|Appare nelle tipologie:||1.1 Articolo in rivista|