Discovering Genes-Diseases Associations From Specialized Literature Using the Grid

This paper proposes a novel method for text mining on the Grid, aimed at pointing out hidden relationships for hypothesis generation and suitable for semi-interactive querying. The method is based on unsupervised clustering and the outputs are visualized with contextual information. Grid implementation is crucial for feasibility. We demonstrate it with a mining run for discovering genes-diseases associations from bibliographic sources and annotated databases. The proposed methodology is in view of a Grid architecture specialized in bioinformatics mining tasks. Some performance considerations are provided. © 2009 IEEE.