Dendrons composed of three functionalized cone calix- arene substructures covalently bound to rigid C3-symmetric tris-anilino cores through amide linkages have been ob- tained by a divergent synthetic protocol involving the cou- pling of p-nitrocalixarene butanoic acid 9 with tris(4-ami- nophenyl)amine (TAPA), 1,3,5-tris(4-aminophenyl)benzene(TAPB), and 2,4,6-tris(4-aminophenyl)-s-triazine (TAPT). Two different amidation procedures were used to generate the dodecanitro intermediates (through activation of acid 9 with PyBOP catalyst or transformation into its acid chloride). The final reduction to the title dodecaamino dendrons was smoothly carried out with H2 and Raney-Ni catalyst.
|Titolo:||Amino Surface-Functionalized Tris(calixarene) Dendrons with Rigid C3- Symmetric Propeller Cores|
|Autori interni:||PAPPALARDO, ANDREA|
|Data di pubblicazione:||2011|
|Rivista:||EUROPEAN JOURNAL OF ORGANIC CHEMISTRY|
|Appare nelle tipologie:||1.1 Articolo in rivista|