TUNDO, GRAZIA RAFFAELLA
TUNDO, GRAZIA RAFFAELLA
SCIENZE CHIMICHE
Aβ40 competitively binds Ubiquitin and inhibits polyubiquitination: a new paradigm for amyloid toxicity
file da validare2018-01-01 Grasso, G.; Bellia, F.; Lanza, V.; García-Viñuales, S.; Pietropaolo, A.; Iacobucci, C.; Malgieri, G.; Fattorusso, R.; Nicoletti, V. G.; Sbardella, D.; Tundo, G. R.; Coletta, M.; Milardi, D.
Modulation of the 20S Proteasome Activity by Porphyrin Derivatives Is Steered through Their Charge Distribution
2022-01-01 Persico, Marco; Santoro, Anna Maria; D'Urso, Alessandro; Milardi, Danilo; Purrello, Roberto; Cunsolo, Alessandra; Gobbo, Marina; Fattorusso, Roberto; Diana, Donatella; Stefanelli, Manuela; Tundo, Grazia R; Sbardella, Diego; Coletta, Massimo; Fattorusso, Caterina
Profiling of the Peripheral Blood Mononuclear Cells Proteome by Shotgun Proteomics Identifies Alterations of Immune System Components, Proteolytic Balance, Autophagy, and Mitochondrial Metabolism in Glaucoma Subjects
2025-01-01 Giammaria, Sara; Pandino, Irene; Zingale, Gabriele Antonio; Atzori, Maria Grazia; Cavaterra, Dario; Cecere, Michela; Michelessi, Manuele; Roberti, Gloria; Tanga, Lucia; Carnevale, Carmela; Vercellin, Alice Verticchio; Siesky, Brent; Harris, Alon; Grasso, Giuseppe; Bocedi, Alessio; Coletta, Massimiliano; Tundo, Grazia Raffaella; Oddone, Francesco; Sbardella, Diego
Pyrazolones activate proteasome by gating mechanisms and protect neuronal cells from Aβ amyloid toxicity
2020-01-01 Maria Santoro, Anna; Lanza, Valeria; Bellia, Francesco; Sbardella, Diego; Tundo, Grazia R.; Cannizzo, Alessandra; Grasso, Giuseppe; Arizzi, Mariaconcetta; Nicoletti, Vincenzo G.; Alcaro, Stefano; Costa, Giosuè; Pietropaolo, Adriana; Malgieri, Gaetano; D'Abrosca, Gianluca; Fattorusso, Roberto; García-Viñuales, Sara; Ahmed, Ikhlas M. M.; Coletta, Massimiliano; Milardi, Danilo
Structural and functional evidence for citicoline binding and modulation of 20S proteasome activity: Novel insights into its pro-proteostatic effect
2020-01-01 Sbardella, Diego; Coletta, Andrea; Tundo, Grazia Raffaella; Ahmed, Ikhlas M. M.; Bellia, Francesco; Oddone, Francesco; Manni, Gianluca; Coletta, Massimo
The Delayed Turnover of Proteasome Processing of Myocilin upon Dexamethasone Stimulation Introduces the Profiling of Trabecular Meshwork Cells’ Ubiquitylome
2024-01-01 Tundo, Grazia Raffaella; Cavaterra, Dario; Pandino, Irene; Zingale, Gabriele Antonio; Giammaria, Sara; Boccaccini, Alessandra; Michelessi, Manuele; Roberti, Gloria; Tanga, Lucia; Carnevale, Carmela; Figus, Michele; Grasso, Giuseppe; Coletta, Massimo; Bocedi, Alessio; Oddone, Francesco; Sbardella, Diego
The Insulin-Degrading Enzyme from Structure to Allosteric Modulation: New Perspectives for Drug Design
2023-01-01 Tundo, Grazia Raffaella; Grasso, Giuseppe; Persico, Marco; Tkachuk, Oleh; Bellia, Francesco; Bocedi, Alessio; Marini, Stefano; Parravano, Mariacristina; Graziani, Grazia; Fattorusso, Caterina; Sbardella, Diego
The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges
file da validare2020-01-01 Tundo, G R; Sbardella, D; Santoro, A M; Coletta, A; Oddone, F; Grasso, G; Milardi, D; Lacal, P; Marini, S; Purrello, R; Graziani, G; Coletta, M
Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways
2019-01-01 Bellia, F.; Lanza, V.; García-Viñuales, S.; Ahmed, I. M. M.; Pietropaolo, A.; Iacobucci, C.; Malgieri, G.; D'Abrosca, G.; Fattorusso, R.; Nicoletti, V. G.; Sbardella, D.; Tundo, G. R.; Coletta, M.; Pirone, L.; Pedone, E.; Calcagno, Damiano; Grasso, G.; Milardi, D.
Ubiquitin-proteasome system derangement in brain pathologies: new neuroprotective strategies
file da validare2018-01-01 Grasso, G.; Arizzi, M.; Calcagno, D.; Cannizzo, A.; Nicoletti, V. G.; Santoro, A. M.; Lanza, V.; Bellia, F.; Sbardella, D.; Tundo, G. R.; Marini, S.; Coletta, M.; Milardi, D.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Aβ40 competitively binds Ubiquitin and inhibits polyubiquitination: a new paradigm for amyloid toxicity | 1-gen-2018 | Grasso, G.; Bellia, F.; Lanza, V.; García-Viñuales, S.; Pietropaolo, A.; Iacobucci, C.; Malgieri, G.; Fattorusso, R.; Nicoletti, V. G.; Sbardella, D.; Tundo, G. R.; Coletta, M.; Milardi, D. | file da validare |
| Modulation of the 20S Proteasome Activity by Porphyrin Derivatives Is Steered through Their Charge Distribution | 1-gen-2022 | Persico, Marco; Santoro, Anna Maria; D'Urso, Alessandro; Milardi, Danilo; Purrello, Roberto; Cunsolo, Alessandra; Gobbo, Marina; Fattorusso, Roberto; Diana, Donatella; Stefanelli, Manuela; Tundo, Grazia R; Sbardella, Diego; Coletta, Massimo; Fattorusso, Caterina | |
| Profiling of the Peripheral Blood Mononuclear Cells Proteome by Shotgun Proteomics Identifies Alterations of Immune System Components, Proteolytic Balance, Autophagy, and Mitochondrial Metabolism in Glaucoma Subjects | 1-gen-2025 | Giammaria, Sara; Pandino, Irene; Zingale, Gabriele Antonio; Atzori, Maria Grazia; Cavaterra, Dario; Cecere, Michela; Michelessi, Manuele; Roberti, Gloria; Tanga, Lucia; Carnevale, Carmela; Vercellin, Alice Verticchio; Siesky, Brent; Harris, Alon; Grasso, Giuseppe; Bocedi, Alessio; Coletta, Massimiliano; Tundo, Grazia Raffaella; Oddone, Francesco; Sbardella, Diego | |
| Pyrazolones activate proteasome by gating mechanisms and protect neuronal cells from Aβ amyloid toxicity | 1-gen-2020 | Maria Santoro, Anna; Lanza, Valeria; Bellia, Francesco; Sbardella, Diego; Tundo, Grazia R.; Cannizzo, Alessandra; Grasso, Giuseppe; Arizzi, Mariaconcetta; Nicoletti, Vincenzo G.; Alcaro, Stefano; Costa, Giosuè; Pietropaolo, Adriana; Malgieri, Gaetano; D'Abrosca, Gianluca; Fattorusso, Roberto; García-Viñuales, Sara; Ahmed, Ikhlas M. M.; Coletta, Massimiliano; Milardi, Danilo | |
| Structural and functional evidence for citicoline binding and modulation of 20S proteasome activity: Novel insights into its pro-proteostatic effect | 1-gen-2020 | Sbardella, Diego; Coletta, Andrea; Tundo, Grazia Raffaella; Ahmed, Ikhlas M. M.; Bellia, Francesco; Oddone, Francesco; Manni, Gianluca; Coletta, Massimo | |
| The Delayed Turnover of Proteasome Processing of Myocilin upon Dexamethasone Stimulation Introduces the Profiling of Trabecular Meshwork Cells’ Ubiquitylome | 1-gen-2024 | Tundo, Grazia Raffaella; Cavaterra, Dario; Pandino, Irene; Zingale, Gabriele Antonio; Giammaria, Sara; Boccaccini, Alessandra; Michelessi, Manuele; Roberti, Gloria; Tanga, Lucia; Carnevale, Carmela; Figus, Michele; Grasso, Giuseppe; Coletta, Massimo; Bocedi, Alessio; Oddone, Francesco; Sbardella, Diego | |
| The Insulin-Degrading Enzyme from Structure to Allosteric Modulation: New Perspectives for Drug Design | 1-gen-2023 | Tundo, Grazia Raffaella; Grasso, Giuseppe; Persico, Marco; Tkachuk, Oleh; Bellia, Francesco; Bocedi, Alessio; Marini, Stefano; Parravano, Mariacristina; Graziani, Grazia; Fattorusso, Caterina; Sbardella, Diego | |
| The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges | 1-gen-2020 | Tundo, G R; Sbardella, D; Santoro, A M; Coletta, A; Oddone, F; Grasso, G; Milardi, D; Lacal, P; Marini, S; Purrello, R; Graziani, G; Coletta, M | file da validare |
| Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways | 1-gen-2019 | Bellia, F.; Lanza, V.; García-Viñuales, S.; Ahmed, I. M. M.; Pietropaolo, A.; Iacobucci, C.; Malgieri, G.; D'Abrosca, G.; Fattorusso, R.; Nicoletti, V. G.; Sbardella, D.; Tundo, G. R.; Coletta, M.; Pirone, L.; Pedone, E.; Calcagno, Damiano; Grasso, G.; Milardi, D. | |
| Ubiquitin-proteasome system derangement in brain pathologies: new neuroprotective strategies | 1-gen-2018 | Grasso, G.; Arizzi, M.; Calcagno, D.; Cannizzo, A.; Nicoletti, V. G.; Santoro, A. M.; Lanza, V.; Bellia, F.; Sbardella, D.; Tundo, G. R.; Marini, S.; Coletta, M.; Milardi, D. | file da validare |