Risk exposure to BPA in a Sicilian population

Scientific concerns about exposure to Bisphenol A (BPA) have risen in the last few years. Recent studies have associated prenatal and neonatal exposure to BPA with early onset of sexual maturation, reproductive and development disorders. BPA is an endocrine disruptor and cardiovascular, renal and diabetic diseases are strongly associated with the presence of urinary BPA. Both low and high single oral doses of BPA are well absorbed and undergo complete first-pass metabolism in the liver to BPA-glucuronide (BPA-glu) as major metabolite, which is rapidly excreted in the urine. Here we present preliminary results on 61 volunteers of 18-66 years old recruited from the province of Catania (Italy) to evaluate urinary exposure to BPA and his major metabolite.