Astenia: una maschera per tante identità. Ruolo della patologia della placca neuromuscolare

Several neuropathological conditions may underlie anacute or chronic, focal or diffuse, condition of fatigue andmuscle weakness,.The pathology of the neuromuscular junction is an exampleof this polymorphism in clinical and neuropathological pictures,as well as two diseases (myasthenia gravis and myasthenicsyndrome) with very different etiology, symptoms and treatment,which must be well recognized for a suitable treatment.This brief review describes the myasthenia and myasthenic syndrome,outlining the similarities and differences in terms ofetiology, symptoms, signs, diagnostic procedures, treatmentoptions and prognosis.