Heterocyclic compounds represent a significant target for anti-cancer research and drug discovery, due to their structural and chemical diversity. Oxazoles, with oxygen and nitrogen atoms present in the core structure, enable various types of interactions with different enzymes and receptors, favoring the discovery of new drugs. Aim of this review is to describe the most recent reports on the use of oxazole-based compounds in anticancer research, with reference to the newly discovered iso/oxazole-based drugs, to their synthesis and to the evaluation of the most biologically active derivatives. The corresponding dehydrogenated derivatives, i.e. iso/oxazolines and iso/oxazolidines, are also reported.
|Titolo:||Oxazole-based compounds as anticancer agents|
CHIACCHIO, MARIA ASSUNTA ROSSELLA (Primo) [Supervision] (Corresponding)
LANZA, GIUSEPPE (Secondo) [Software]
CHIACCHIO, Ugo (Penultimo) [Conceptualization]
LEGNANI, LAURA (Ultimo) [Methodology]
|Data di pubblicazione:||2019|
|Appare nelle tipologie:||1.1 Articolo in rivista|