Probiotics and prebiotics in the management of constipation in the elderly

The prevalence of constipation and its impact on quality of life are high among elderly people, with a incidence of 26% inmen and 34% in women aged 65 or more. The current standard treatment consists of laxatives administration, lifestyle modificationssuch as regular physical activity and increased fluids and fibers intake. Several studies have demonstrated that modificationsin the intestinal microflora of elderly could alter the metabolic environment of the colon with important changes in the concentrationof physiologically active substances that may alter the motor and secretory functions of the bowel. Probiotics are live microorganisms(such as Bifidobacteria and Lactobacilli), which, when administered in adequate amounts, confer a health benefit to thehost. Studies examining the effects of probiotics on constipation in elderly are limited, and different strains have been used so far.The aim of this review is to summarize the best available data and indications regarding probiotics as a tool for the management ofconstipation in the elderly.