Methoxypyrimidines preferentially add to benzonitrile oxide to give cycloadducts to their C=N double bonds. These, however, lose benzonitrile affording the corresponding pyrimidones. Cycloadditions to their C=C double bonds take place to a very low extent, and products generally undergo a ring opening process which affords the corresponding oximes. Pyrimidones preferentially give addition products to their nitrogen atoms, and only in the case of 4-pyrimidone, the cycloadduct to its C=C double bond was isolated.
|Titolo:||Reactions of benzonitrile oxide with methoxypyrimidines and pyrimidones|
|Autori interni:||CHIACCHIO, MARIA ASSUNTA ROSSELLA|
|Data di pubblicazione:||2005|
|Appare nelle tipologie:||1.1 Articolo in rivista|