Sfoglia per Autore
Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review
2018-01-01 Turnaturi, Rita; Marrazzo, Agostino; Parenti, Carmela; Pasquinucci, Lorella
A structure-and ligand-based virtual screening of a database of “small” marine natural products for the identification of “blue” sigma-2 receptor ligands
2018-01-01 Floresta, Giuseppe; Amata, Emanuele; Barbaraci, Carla; Gentile, Davide; Turnaturi, Rita; Marrazzo, Agostino; Rescifina, Antonio
Influenza del N-sostituente della (–)-cis-N-Normetazocina nella modulazione del profilo funzionale al MOR, DOR e KOR: da agonista ad antagonista attraverso ligandi misti agonisti/antagonisti
2019-01-01 Turnaturi, Rita; Parenti, Carmela; Georgoussi, Zafiroula; Calò, Girolamo; Amata, Emanuele; Marrazzo, Agostino; Pasquinucci, Lorella Giuseppina
Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain
2019-01-01 Vicario, Nunzio; Pasquinucci, Lorella; Spitale, Federica M.; Chiechio, Santina; Turnaturi, Rita; Caraci, Filippo; Tibullo, Daniele; Avola, Roberto; Gulino, Rosario; Parenti, Rosalba; Parenti, Carmela
Simultaneous activation of mu and delta opioid receptors reduces allodynia and astrocytic connexin 43 in an animal model of neuropathic pain
2019-01-01 Vicario, Nunzio; Pasquinucci, Lorella; Spitale, Federica M.; Chiechio, Santina; Turnaturi, Rita; Caraci, Filippo; Tibullo, Daniele; Avola, Roberto; Gulino, Rosario; Parenti, Rosalba; Parenti, Carmela
LP2 e 2S-LP2: agonisti biased dual target MOR/DOR nel trattamento del dolore cronico
2019-01-01 Pasquinucci, Lorella; Parenti, Carmela; Chiechio, Santina; Calò, Girolamo; Parenti, Rosalba; Vicario, Nunzio; Turnaturi, Rita
Progress in the development of more effective and safer analgesics for pain management
2019-01-01 Turnaturi, R.; Chiechio, S.; Salerno, L.; Rescifina, A.; Pittala, V.; Cantarella, G.; Tomarchio, E.; Parenti, C.; Pasquinucci, L.
Simultaneous targeting of MOR/DOR: A useful strategy for inflammatory pain modulation
2019-01-01 Pasquinucci, Lorella; Turnaturi, Rita; Montenegro, Lucia; Caraci, Filippo; Chiechio, Santina; Parenti, Carmela
((2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist
2019-01-01 Pasquinucci, Lorella; Turnaturi, Rita; Calò, Girolamo; Pappalardo, Francesco; Ferrari, Federica; Russo, Giulia; Arena, Emanuela; Montenegro, Lucia; Chiechio, Santina; Prezzavento, Orazio; Parenti, Carmela
Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application
2019-01-01 Salerno, Loredana; Floresta, Giuseppe; Ciaffaglione, Valeria; Gentile, Davide; Margani, Fatima; Turnaturi, Rita; Rescifina, Antonio; Pittalà, Valeria
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands
2019-01-01 Romeo, Giuseppe; Prezzavento, Orazio; Intagliata, Sebastiano; Pittalà, Valeria; Modica, Maria N.; Marrazzo, Agostino; Turnaturi, Rita; Parenti, Carmela; Chiechio, Santina; Arena, Emanuela; Campisi, Agatina; Sposito, Giovanni; Salerno, Loredana
In Vitro Antioxidant Activity and In Vivo Topical Efficacy of Lipid Nanoparticles Co-Loading Idebenone and Tocopheryl Acetate
2019-01-01 Montenegro, Lucia; Messina, Concetta Sabina; Manuguerra, Simona; Santagati, Ludovica; Pasquinucci, Lorella; Turnaturi, Rita; Parenti, Carmela; Arena, Rosaria; Santulli, Andrea
Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists
2020-01-01 Pasquinucci, Lorella; Parenti, Carmela; Ruiz-Cantero M., Carmen; Georgoussi, Zafiroula; Pallaki, Paschalina; Cobos J., Enrique; Amata, Emanuele; Marrazzo, Agostino; Prezzavento, Orazio; Arena, Emanuela; Dichiara, Maria; Salerno, Loredana; Turnaturi, Rita
Tuning Properties for Blood-Brain Barrier Permeation: A Statistics-Based Analysis
2020-01-01 Dichiara, Maria; Amata, Benedetto; Turnaturi, Rita; Marrazzo, Agostino; Amata, Emanuele
Intercellular communication and ion channels in neuropathic pain chronicization
2020-01-01 Vicario, N.; Turnaturi, R.; Spitale, F. M.; Torrisi, F.; Zappala, A.; Gulino, R.; Pasquinucci, L.; Chiechio, S.; Parenti, C.; Parenti, R.
Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation
2020-01-01 Amata, Emanuele; Dichiara, Maria; Gentile, Davide; Marrazzo, Agostino; Turnaturi, Rita; Arena, Emanuela; La Mantia, Alfonsina; Tomasello, Barbara; Acquaviva, Rosaria; DI GIACOMO, Claudia; Rescifina, Antonio; Prezzavento, Orazio
Exploiting the Power of Stereochemistry in Drug Action: 3-[(2S,6S,11S)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide as Potent Sigma-1 Receptor Antagonist
2020-01-01 Turnaturi, Rita; Pasquinucci, Lorella; Chiechio, Santina; Grasso, Margherita; Marrazzo, Agostino; Amata, Emanuele; Dichiara, Maria; Prezzavento, Orazio; Parenti, Carmela
Design, Synthesis and biological evaluation of hybrid MOR agonist/ HDACi molecules as potential therapeutic agents for chronic pain treatment
file da validare2021-01-01 Costanzo, Giuliana; Turnaturi, Rita; Barbaraci, Carla; Marrazzo, Agostino; Pasquinucci, Lorella Giuseppina
Design, synthesis and biological evaluation of MOR agonist/HDACi hybrid compounds: a new potential therapeutic strategy for persistent pain management
2021-01-01 Costanzo, Giuliana; Turnaturi, Rita; Marrazzo, Agostino; Pasquinucci, Lorella
Hybrid MOR agonist/HDACi molecules as potential new drugs for persistant pain management: design, synthesis and biological evaluation
file da validare2021-01-01 Costanzo, Giuliana; Turnaturi, Rita; Marrazzo, Agostino; Pasquinucci, Lorella Giuseppina
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review | 1-gen-2018 | Turnaturi, Rita; Marrazzo, Agostino; Parenti, Carmela; Pasquinucci, Lorella | |
| A structure-and ligand-based virtual screening of a database of “small” marine natural products for the identification of “blue” sigma-2 receptor ligands | 1-gen-2018 | Floresta, Giuseppe; Amata, Emanuele; Barbaraci, Carla; Gentile, Davide; Turnaturi, Rita; Marrazzo, Agostino; Rescifina, Antonio | |
| Influenza del N-sostituente della (–)-cis-N-Normetazocina nella modulazione del profilo funzionale al MOR, DOR e KOR: da agonista ad antagonista attraverso ligandi misti agonisti/antagonisti | 1-gen-2019 | Turnaturi, Rita; Parenti, Carmela; Georgoussi, Zafiroula; Calò, Girolamo; Amata, Emanuele; Marrazzo, Agostino; Pasquinucci, Lorella Giuseppina | |
| Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain | 1-gen-2019 | Vicario, Nunzio; Pasquinucci, Lorella; Spitale, Federica M.; Chiechio, Santina; Turnaturi, Rita; Caraci, Filippo; Tibullo, Daniele; Avola, Roberto; Gulino, Rosario; Parenti, Rosalba; Parenti, Carmela | |
| Simultaneous activation of mu and delta opioid receptors reduces allodynia and astrocytic connexin 43 in an animal model of neuropathic pain | 1-gen-2019 | Vicario, Nunzio; Pasquinucci, Lorella; Spitale, Federica M.; Chiechio, Santina; Turnaturi, Rita; Caraci, Filippo; Tibullo, Daniele; Avola, Roberto; Gulino, Rosario; Parenti, Rosalba; Parenti, Carmela | |
| LP2 e 2S-LP2: agonisti biased dual target MOR/DOR nel trattamento del dolore cronico | 1-gen-2019 | Pasquinucci, Lorella; Parenti, Carmela; Chiechio, Santina; Calò, Girolamo; Parenti, Rosalba; Vicario, Nunzio; Turnaturi, Rita | |
| Progress in the development of more effective and safer analgesics for pain management | 1-gen-2019 | Turnaturi, R.; Chiechio, S.; Salerno, L.; Rescifina, A.; Pittala, V.; Cantarella, G.; Tomarchio, E.; Parenti, C.; Pasquinucci, L. | |
| Simultaneous targeting of MOR/DOR: A useful strategy for inflammatory pain modulation | 1-gen-2019 | Pasquinucci, Lorella; Turnaturi, Rita; Montenegro, Lucia; Caraci, Filippo; Chiechio, Santina; Parenti, Carmela | |
| ((2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist | 1-gen-2019 | Pasquinucci, Lorella; Turnaturi, Rita; Calò, Girolamo; Pappalardo, Francesco; Ferrari, Federica; Russo, Giulia; Arena, Emanuela; Montenegro, Lucia; Chiechio, Santina; Prezzavento, Orazio; Parenti, Carmela | |
| Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application | 1-gen-2019 | Salerno, Loredana; Floresta, Giuseppe; Ciaffaglione, Valeria; Gentile, Davide; Margani, Fatima; Turnaturi, Rita; Rescifina, Antonio; Pittalà, Valeria | |
| Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands | 1-gen-2019 | Romeo, Giuseppe; Prezzavento, Orazio; Intagliata, Sebastiano; Pittalà, Valeria; Modica, Maria N.; Marrazzo, Agostino; Turnaturi, Rita; Parenti, Carmela; Chiechio, Santina; Arena, Emanuela; Campisi, Agatina; Sposito, Giovanni; Salerno, Loredana | |
| In Vitro Antioxidant Activity and In Vivo Topical Efficacy of Lipid Nanoparticles Co-Loading Idebenone and Tocopheryl Acetate | 1-gen-2019 | Montenegro, Lucia; Messina, Concetta Sabina; Manuguerra, Simona; Santagati, Ludovica; Pasquinucci, Lorella; Turnaturi, Rita; Parenti, Carmela; Arena, Rosaria; Santulli, Andrea | |
| Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists | 1-gen-2020 | Pasquinucci, Lorella; Parenti, Carmela; Ruiz-Cantero M., Carmen; Georgoussi, Zafiroula; Pallaki, Paschalina; Cobos J., Enrique; Amata, Emanuele; Marrazzo, Agostino; Prezzavento, Orazio; Arena, Emanuela; Dichiara, Maria; Salerno, Loredana; Turnaturi, Rita | |
| Tuning Properties for Blood-Brain Barrier Permeation: A Statistics-Based Analysis | 1-gen-2020 | Dichiara, Maria; Amata, Benedetto; Turnaturi, Rita; Marrazzo, Agostino; Amata, Emanuele | |
| Intercellular communication and ion channels in neuropathic pain chronicization | 1-gen-2020 | Vicario, N.; Turnaturi, R.; Spitale, F. M.; Torrisi, F.; Zappala, A.; Gulino, R.; Pasquinucci, L.; Chiechio, S.; Parenti, C.; Parenti, R. | |
| Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation | 1-gen-2020 | Amata, Emanuele; Dichiara, Maria; Gentile, Davide; Marrazzo, Agostino; Turnaturi, Rita; Arena, Emanuela; La Mantia, Alfonsina; Tomasello, Barbara; Acquaviva, Rosaria; DI GIACOMO, Claudia; Rescifina, Antonio; Prezzavento, Orazio | |
| Exploiting the Power of Stereochemistry in Drug Action: 3-[(2S,6S,11S)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide as Potent Sigma-1 Receptor Antagonist | 1-gen-2020 | Turnaturi, Rita; Pasquinucci, Lorella; Chiechio, Santina; Grasso, Margherita; Marrazzo, Agostino; Amata, Emanuele; Dichiara, Maria; Prezzavento, Orazio; Parenti, Carmela | |
| Design, Synthesis and biological evaluation of hybrid MOR agonist/ HDACi molecules as potential therapeutic agents for chronic pain treatment | 1-gen-2021 | Costanzo, Giuliana; Turnaturi, Rita; Barbaraci, Carla; Marrazzo, Agostino; Pasquinucci, Lorella Giuseppina | file da validare |
| Design, synthesis and biological evaluation of MOR agonist/HDACi hybrid compounds: a new potential therapeutic strategy for persistent pain management | 1-gen-2021 | Costanzo, Giuliana; Turnaturi, Rita; Marrazzo, Agostino; Pasquinucci, Lorella | |
| Hybrid MOR agonist/HDACi molecules as potential new drugs for persistant pain management: design, synthesis and biological evaluation | 1-gen-2021 | Costanzo, Giuliana; Turnaturi, Rita; Marrazzo, Agostino; Pasquinucci, Lorella Giuseppina | file da validare |
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