A palladium-catalyzed diamination domino process of sulfamates arising from glycine allylamides isreported. The reaction leads to the formation of [1,2,5]thiadiazolo-fused piperazinones. The essentialfeature of the synthetic route is the use of PdCl2(MeCN)2/CuBr2, as a catalytic system which promotesthe second amination process, leading to the bicycle ring-fused compounds in good yields.

Intramolecular oxidative palladium-​catalyzed diamination reactions of alkenyl sulfamates: an efficient synthesis of [1,​2,​5]​thiadiazolo-​fused piperazinones

Chiacchio U;Floresta G;Zagni C;Chiacchio M
2016-01-01

Abstract

A palladium-catalyzed diamination domino process of sulfamates arising from glycine allylamides isreported. The reaction leads to the formation of [1,2,5]thiadiazolo-fused piperazinones. The essentialfeature of the synthetic route is the use of PdCl2(MeCN)2/CuBr2, as a catalytic system which promotesthe second amination process, leading to the bicycle ring-fused compounds in good yields.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11769/46710
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