The results of studies on the design of a heterocyclic scaffold for the dynorphin A pharmacophore and on structure-affinity relationships in the MPCB/CCB series are described. The representative ligands provide insights to binding modes of benzomorphan derivatives to the κ opioid receptor.
Specific kappa opioid receptor agonists
RONSISVALLE, Giuseppe;MARRAZZO, Agostino;PASQUINUCCI, Lorella Giuseppina;
2001-01-01
Abstract
The results of studies on the design of a heterocyclic scaffold for the dynorphin A pharmacophore and on structure-affinity relationships in the MPCB/CCB series are described. The representative ligands provide insights to binding modes of benzomorphan derivatives to the κ opioid receptor.File in questo prodotto:
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