LEGGIO, GIAN MARCO
 Distribuzione geografica
Continente #
NA - Nord America 5.424
EU - Europa 2.358
AS - Asia 2.285
SA - Sud America 479
AF - Africa 322
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 4
Totale 10.877
Nazione #
US - Stati Uniti d'America 5.253
SG - Singapore 1.147
IT - Italia 1.144
CN - Cina 749
BR - Brasile 428
IE - Irlanda 391
UA - Ucraina 221
CI - Costa d'Avorio 216
RU - Federazione Russa 174
CA - Canada 144
VN - Vietnam 112
DE - Germania 91
KR - Corea 72
SN - Senegal 63
GB - Regno Unito 57
SE - Svezia 46
NL - Olanda 41
IN - India 39
FI - Finlandia 34
FR - Francia 33
BE - Belgio 25
JP - Giappone 23
BD - Bangladesh 21
ES - Italia 21
PL - Polonia 21
CH - Svizzera 16
ZA - Sudafrica 16
TR - Turchia 15
MX - Messico 14
AR - Argentina 13
HK - Hong Kong 12
IR - Iran 12
IQ - Iraq 11
LB - Libano 11
BJ - Benin 10
ID - Indonesia 10
UZ - Uzbekistan 10
AT - Austria 9
EC - Ecuador 9
LT - Lituania 9
PK - Pakistan 9
CO - Colombia 7
GR - Grecia 6
AZ - Azerbaigian 5
CZ - Repubblica Ceca 5
SA - Arabia Saudita 5
VE - Venezuela 5
AE - Emirati Arabi Uniti 4
CL - Cile 4
DZ - Algeria 4
EU - Europa 4
JM - Giamaica 4
KE - Kenya 4
PE - Perù 4
PY - Paraguay 4
BG - Bulgaria 3
DO - Repubblica Dominicana 3
IL - Israele 3
JO - Giordania 3
NP - Nepal 3
NZ - Nuova Zelanda 3
UY - Uruguay 3
AU - Australia 2
BA - Bosnia-Erzegovina 2
BO - Bolivia 2
EG - Egitto 2
KZ - Kazakistan 2
NI - Nicaragua 2
RO - Romania 2
TN - Tunisia 2
TW - Taiwan 2
AL - Albania 1
AO - Angola 1
BH - Bahrain 1
CR - Costa Rica 1
DK - Danimarca 1
ET - Etiopia 1
HN - Honduras 1
KG - Kirghizistan 1
LK - Sri Lanka 1
LU - Lussemburgo 1
LV - Lettonia 1
MA - Marocco 1
NO - Norvegia 1
OM - Oman 1
PA - Panama 1
PT - Portogallo 1
SM - San Marino 1
TG - Togo 1
TH - Thailandia 1
TT - Trinidad e Tobago 1
TZ - Tanzania 1
Totale 10.877
Città #
Santa Clara 842
Dallas 837
Houston 587
Singapore 581
Chandler 469
Dublin 386
Catania 326
Jacksonville 296
Chicago 277
Abidjan 216
Ashburn 184
Boardman 168
Hefei 150
Beijing 108
Andover 104
Cambridge 103
Lawrence 102
Toronto 93
Nanjing 88
Los Angeles 85
Messina 76
Civitanova Marche 73
Seoul 72
Des Moines 65
Dakar 63
Council Bluffs 45
Moscow 45
Florence 43
Wilmington 43
New York 39
Ottawa 34
Palermo 32
Shenyang 32
The Dalles 32
Ho Chi Minh City 31
Hebei 30
São Paulo 30
Amsterdam 28
Columbus 28
Bremen 27
Saint Petersburg 27
San Mateo 27
Changsha 26
Munich 26
Jiaxing 25
Rome 24
Hanoi 23
Nanchang 23
Falls Church 22
Tianjin 22
Dong Ket 21
Buffalo 19
Rio de Janeiro 18
Seattle 18
Tokyo 18
Brooklyn 17
Kraainem 16
Milan 15
Guangzhou 14
Warsaw 14
Dearborn 13
Denver 13
Grafing 13
Helsinki 13
Jinan 13
Johannesburg 13
Washington 11
Cotonou 10
Curitiba 10
Hong Kong 10
Lappeenranta 10
Montreal 10
Redwood City 10
Zhengzhou 10
Aci Catena 9
Belo Horizonte 9
Brasília 9
Brussels 9
Mascalucia 9
Naples 9
Orem 9
Atlanta 8
Padova 8
Paternò 8
Phoenix 8
Poplar 8
Campinas 7
Chennai 7
Haiphong 7
Irvine 7
London 7
Misterbianco 7
Ningbo 7
Providence 7
Pune 7
Redondo Beach 7
San Francisco 7
Shanghai 7
Trento 7
Turku 7
Totale 7.645
Nome #
Dopamine D3 receptor deletion increases tissue plasminogen activator (tPA) activity in prefrontal cortex and hippocampus. 551
A novel arousal-based individual screening reveals susceptibility and resilience to PTSD-like phenotypes in mice 227
Current drug treatments targeting dopamine D3 receptor 202
Dopaminergic-GABAergic interplay and alcohol binge drinking 189
Fluoxetine and Vortioxetine Reverse Depressive-Like Phenotype and Memory Deficits Induced by Aβ1-42 Oligomers in Mice: A Key Role of Transforming Growth Factor-β1 164
Blockade of dopamine D3 receptors improves hippocampal synaptic function and rescues age‐related cognitive phenotype 145
The epistatic interaction between the dopamine D3 receptor and dysbindin-1 modulates higher-order cognitive functions in mice and humans 145
Antioxidant Activity of Fluoxetine and Vortioxetine in a Non-Transgenic Animal Model of Alzheimer’s Disease 141
Sulodexide prevents activation of the PLA2/COX-2/VEGF inflammatory pathway in human retinal endothelial cells by blocking the effect of AGE/RAGE 139
Anthocyanin Effects on Vascular and Endothelial Health: Evidence from Clinical Trials and Role of Gut Microbiota Metabolites 138
A new human blood–retinal barrier model based on endothelial cells, pericytes, and astrocytes 137
Pharmacological enhancement of cholinergic neurotransmission alleviates neuroinflammation and improves functional outcomes in a triple transgenic mouse model of Alzheimer’s disease 134
The antineoplastic drug flavopiridol reverses memory impairment induced by Amyloid-ß1-42 oligomers in mice 132
Computational systems biology approach to identify novel pharmacological targets for diabetic retinopathy 130
Buspirone counteracts MK-801-induced schizophrenia-like phenotypes through dopamine D3receptor blockade 129
A water-soluble carbon monoxide-releasing molecule (CORM-3) lowers intraocular pressure in rabbits 123
Blood-retinal barrier protection against high glucose damage: The role of P2X7 receptor 122
Neurobiological links between depression and AD: the role of TGF-β1 signaling as a new pharmacological target 120
Retinal biomarkers and pharmacological targets for Hermansky-Pudlak syndrome 7 120
Identification of Dysregulated microRNA Networks in Schwann Cell-Like Cultures Exposed to Immune Challenge: Potential Crosstalk with the Protective VIP/PACAP Neuropeptide System 119
Behavioral and neurochemical changes induced by stress-related conditions are counteracted by the neurokinin-2 receptor antagonist saredutant 114
Aflibercept regulates retinal inflammation elicited by high glucose via the PlGF/ERK pathway 114
Epigenetic drugs for Alzheimer's disease: hopes and challenges 113
L'uso dell'acido alfa-lipoico in neurologia 112
Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems 111
The beta3 adrenoceptor agonist, amibegron (SR58611A) counteracts stress-induced behavioral and neurochemical changes 110
Dopamine D3 Receptor, Cognition and Cognitive Dysfunctions in Neuropsychiatric Disorders: From the Bench to the Bedside 102
Gut microbiota alterations promote traumatic stress susceptibility associated with p-cresol-induced dopaminergic dysfunctions 102
P2X7 receptor antagonism: implications in diabetic retinopathy 102
Dopamine D-3 receptor as a new pharmacological target for the treatment of depression 102
APP expression in dopamine D3 receptor knock out mice brain during memory consolidation 100
Topical ocular delivery of TGF-β1 to the back of the eye: Implications in age-related neurodegenerative diseases 99
Retinal protection and distribution of curcumin in vitro and in vivo 98
Genetic blockade of the dopamine D3 receptor enhances hippocampal expression of PACAP and receptors and alters their cortical distribution 96
PLGA-PEG NANOPARTICLES LOADED WITH ANTIPSYCHOTIC AGENTS: INFLUENCE OF DRUG MOLECULES ON THE CRYOPROTECTIVE EFFECT OF SUCROSE. 96
Anxiolytic effects in mice of a dual blocker of fatty acid amide hydrolase and transient receptor potential vanilloid type-1 channels 96
Dysregulation of miR-15a-5p, miR-497a-5p and miR-511-5p Is Associated with Modulation of BDNF and FKBP5 in Brain Areas of PTSD-Related Susceptible and Resilient Mice 96
Molecular Effects of Chronic Exposure to Palmitate in Intestinal Organoids: A New Model to Study Obesity and Diabetes 95
Behavioral effects of the β3 adrenoceptor agonist SR58611A: Is it the putative prototype of a new class of antidepressant/anxiolytic drugs? 95
Dopamine, cognitive impairments and second-generation antipsychotics: From mechanistic advances to more personalized treatments 94
Homology modeling of dopamine D2 and D3 receptors: molecular dynamics refinement and docking evaluation 93
Dopamine D3 receptor, neurofibromin and amyloid precursor protein expression during learning 93
Beavioral effects of SR 58611A, a beta-3 agonist, on experimental models of mild stress 93
Behavioral effects of saredutant, a tachykinin NK2 receptor antagonist, in experimental models of mood disorders under basal and stress-related conditions 93
Regulation of intraocular pressure in mice: structural analysis of dopaminergic and serotonergic systems in response to cabergoline 92
Dopamine D3 receptor knockout mice exhibit increased hippocampal cAMP response element binding protein (CREB) following acquisition of passive avoidance memory 91
Dopamine D3 receptor-dependent changes in alpha6 GABAA subunit expression in striatum modulate anxiety-like behaviour: Responsiveness and tolerance to diazepam 91
Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach 91
The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis 90
Amnesia induced by beta-amyloid peptide in dopamine D3 knock-out (KO) mice Is affectedby a cannabinoid CB1 receptor antagonist 90
Therapeutic Challenges of Post-traumatic Stress Disorder: Focus on the Dopaminergic System 90
Fortified extract of red berry, Ginkgo biloba, and white willow bark in experimental early diabetic retinopathy 88
Dopamine D3 receptor is necessary for ethanol consumption: an approach with buspirone 85
Cognitive effects of SL65.0155, a serotonin 5-HT4 receptor partial agonist, in animal models of amnesia 85
TGF-β1 prevents rat retinal insult induced by amyloid-β (1–42) oligomers 85
Dopamine outside the brain: The eye, cardiovascular system and endocrine pancreas 85
Polyphenols and neuroprotection: Therapeutic implications for cognitive decline 84
Sex dimorphism controls dysbindin-related cognitive dysfunctions in mice and humans with the contribution of COMT 83
Long-lasting rescue of schizophrenia-relevant cognitive impairments via risperidone-loaded microPlates 83
Behavioral modifications induced by dietary cholesterol in rats 83
Fluoxetine prevents Aβ1-42-induced toxicity via a paracrine signaling mediated by transforming-growth-factor-β1 83
Cortico-cortical transfer of socially derived information gates emotion recognition 82
Dopamine-3 receptor modulates intraocular pressure: implications for glaucoma 82
Hippocampal neurofibromin and amyloid precursor protein expression in dopamine D3 receptor knock-out mice following passive avoidance conditioning. 81
Cannabinoid CB1 receptor blockade effects memory capacity of dopamine D3 KO mice pre-treated with β-amyloid peptide 80
New pharmacological strategies for treatment of Alzheimer’s disease: focus on disease-modifying drugs 75
Effects of Topical Fucosyl-Lactose, a Milk Oligosaccharide, on Dry Eye Model: An Example of Nutraceutical Candidate 74
Effects of citalopram combined with memantine in forced swimming test in rats 74
Clinical pharmacology of novel anti-Alzheimer disease modifying medications. 74
High Glucose Exposure Impairs L-Cell Differentiation in Intestinal Organoids: Molecular Mechanisms and Clinical Implications 74
Influence of inulin on plasma isoflavone concentrations in healthy postmenopausal women 73
Enhanced expression of PACAP and of its high affinity receptor (PAC1) in the hippocampus and cerebral cortex of dopamine D3 knockout mice. 73
Dopamine D(3) receptor knock-out mice exhibit increased behavioral sensitivity to the anxiolytic drug diazepam 72
Dopamine D3 receptor modulates tissue type plasminogen activator (tPA) activity in mouse brain 72
The Role of Dopamine D3 Receptors, Dysbindin, and Their Functional Interaction in the Expression of Key Genes for Neuroplasticity and Neuroinflammation in the Mouse Brain 71
Oral Echinacea purpurea extract in low-grade, steroid-dependent, autoimmune idiopathic uveitis: a pilot study 71
Cognitive effects of SL65.0155, a serotonin 5-HT4 receptor partial agonist, in animal models of amnesia 69
Molecular basis of alcohol intake: role of D3 dopaminergic receptor 69
Enhanced expression of PACAP and of its high affinity receptor (PAC1) in the hippocampus and cerebral cortex of dopamine D3 knockout mice 69
New drugs in psychiatry: Focus on new pharmacological targets 68
Physiological and therapeutic relevance of constitutive activity at 5HT2C receptors 67
Flavopiridol, an inhibitor of cyclin-dependent kinase 4, reverses cognitive deficits induced by β-amyloid peptide 1–42 67
Ultra-Processed Food Consumption and Depressive Symptoms in a Mediterranean Cohort 66
Serotonin(2C) receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens 66
D3 dopamine receptor knockout mice: behavioral alteration in experimental models of anxiety 66
In vivo evidence that constitutive activity of serotonin2C receptors in the medial prefrontal cortex participates in the control of dopamine release in the rat nucleus accumbens: differential effects of inverse agonist versus antagonist 65
Dysbindin-1A modulation of astrocytic dopamine and basal ganglia dependent behaviors relevant to schizophrenia 64
Neurofibromin and amyloid precursor protein expression in dopamine d3 receptor knock-out mice brains 64
Parkin expression profile in dopamine d3 receptor knock-out mice brains 64
Tackling dipeptidyl peptidase IV in neurological disorders 64
Role of the endocannabinoid system and vanilloid TRPV1 channels in the phenotype of dopamine D3 receptor knock-out mice 63
Increased hippocampal CREB phosphorylation in dopamine D3 receptor knockout mice following passive avoidance conditioning. 63
Involvement of NK2 receptors in experimental models of anxiety and depression under basal and stress-related conditions 63
The amnesic effects induced by β-amyloidfragment 1–42 involve cannabinoid neurotransmission in the brain 62
New antipsychotic drugs for the treatment of agitation and psychosis in Alzheimer's disease: Focus on brexpiprazole and pimavanserin 62
Increased sensitivity to antidepressants of D(3) dopamine receptor-deficient mice in the forced swim test (FST) 61
Effects Of COOH-terminal tripeptide alpha-MSH (11-13) on corneal epithelial wound healing:role of nitric oxide 61
Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats. 61
International union of basic and clinical pharmacology CIV: The neurobiology of treatment-resistant depression: From antidepressant classifications to novel pharmacological targets 61
Effects of COOH–Terminal Tripeptide –MSH11–13 on Corneal Epithelial Wound Healing: Role of Nitric Oxide 60
Totale 9.878
Categoria #
all - tutte 38.027
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 38.027


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021506 0 0 0 0 146 28 128 4 67 22 67 44
2021/2022858 102 112 15 18 135 45 114 27 63 7 34 186
2022/20231.427 116 92 18 163 143 215 17 264 327 6 41 25
2023/2024674 44 80 42 33 24 166 10 54 3 22 118 78
2024/20253.136 58 441 154 243 699 435 115 155 222 222 212 180
2025/20262.803 348 292 981 427 755 0 0 0 0 0 0 0
Totale 11.134