IRIS
LEGGIO, GIAN MARCO
 Distribuzione geografica
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Continente #
NA - Nord America 2.686
EU - Europa 1.719
AS - Asia 459
AF - Africa 184
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 4
SA - Sud America 1
Totale 5.058
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Nazione #
US - Stati Uniti d'America 2.548
IT - Italia 708
IE - Irlanda 414
CN - Cina 366
UA - Ucraina 239
CA - Canada 138
CI - Costa d'Avorio 122
RU - Federazione Russa 112
SN - Senegal 62
DE - Germania 58
SE - Svezia 43
FR - Francia 30
VN - Vietnam 27
BE - Belgio 25
GB - Regno Unito 25
IN - India 17
CH - Svizzera 13
IR - Iran 11
SG - Singapore 10
LB - Libano 9
AT - Austria 8
ES - Italia 8
NL - Olanda 7
GR - Grecia 6
JP - Giappone 6
UZ - Uzbekistan 6
PL - Polonia 5
CZ - Repubblica Ceca 4
EU - Europa 4
BG - Bulgaria 3
FI - Finlandia 3
NZ - Nuova Zelanda 3
AU - Australia 2
NO - Norvegia 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
BR - Brasile 1
DK - Danimarca 1
HK - Hong Kong 1
KR - Corea 1
LK - Sri Lanka 1
LT - Lituania 1
LU - Lussemburgo 1
PT - Portogallo 1
SM - San Marino 1
TH - Thailandia 1
TR - Turchia 1
TW - Taiwan 1
Totale 5.058
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Città #
Houston 584
Chandler 502
Dublin 412
Jacksonville 316
Catania 203
Abidjan 122
Andover 112
Cambridge 110
Lawrence 109
Nanjing 101
Toronto 99
Ashburn 74
Des Moines 69
Florence 63
Dakar 62
Messina 52
Boardman 49
Wilmington 48
Ottawa 37
Hebei 32
San Mateo 31
Shenyang 31
Saint Petersburg 30
Bremen 28
Changsha 27
Jiaxing 27
Nanchang 25
Tianjin 25
Falls Church 22
Dong Ket 21
Kraainem 16
Seattle 16
Beijing 15
Jinan 14
Dearborn 13
Grafing 13
Washington 12
Zhengzhou 11
Los Angeles 10
Redwood City 10
Rome 10
Brussels 9
Pune 9
Guangzhou 8
Ningbo 8
Palermo 8
Irvine 7
Naples 7
Caltanissetta 6
Hanoi 6
Liberty Lake 6
Moscow 6
Padova 6
Providence 6
Taizhou 6
Vicenza 6
Kunming 5
Siracusa 5
Tappahannock 5
Amiens 4
Arezzo 4
Barcelona 4
Den Haag 4
Foggia 4
Fremont 4
Hangzhou 4
Leawood 4
Maruggio 4
Mascalucia 4
Paterno 4
Paternò 4
Avola 3
Bari 3
Bologna 3
Bronte 3
Camerino 3
Fuzhou 3
Kiev 3
Lanzhou 3
Milan 3
Modena 3
Owensboro 3
Pedara 3
San Giovanni la Punta 3
Sesto Fiorentino 3
Tokyo 3
Vercelli 3
Aci Catena 2
Amsterdam 2
Arrecife 2
Assago 2
Auckland 2
Belpasso 2
Catanzaro 2
Chicago 2
Civitavecchia 2
Enna 2
Fairfield 2
Ferrara 2
Frankfurt Am Main 2
Totale 3.804
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Nome #
Dopamine D3 receptor deletion increases tissue plasminogen activator (tPA) activity in prefrontal cortex and hippocampus. 508
Current drug treatments targeting dopamine D3 receptor 141
A novel arousal-based individual screening reveals susceptibility and resilience to PTSD-like phenotypes in mice 117
Dopaminergic-GABAergic interplay and alcohol binge drinking 100
Sulodexide prevents activation of the PLA2/COX-2/VEGF inflammatory pathway in human retinal endothelial cells by blocking the effect of AGE/RAGE 89
Fluoxetine and Vortioxetine Reverse Depressive-Like Phenotype and Memory Deficits Induced by Aβ1-42 Oligomers in Mice: A Key Role of Transforming Growth Factor-β1 87
L'uso dell'acido alfa-lipoico in neurologia 82
The epistatic interaction between the dopamine D3 receptor and dysbindin-1 modulates higher-order cognitive functions in mice and humans 71
Behavioral and neurochemical changes induced by stress-related conditions are counteracted by the neurokinin-2 receptor antagonist saredutant 65
Buspirone counteracts MK-801-induced schizophrenia-like phenotypes through dopamine D3receptor blockade 65
Blood-retinal barrier protection against high glucose damage: The role of P2X7 receptor 63
Dopamine D3 receptor, neurofibromin and amyloid precursor protein expression during passive avoidance learning 62
Retinal biomarkers and pharmacological targets for Hermansky-Pudlak syndrome 7 62
P2X7 receptor antagonism: implications in diabetic retinopathy 61
Neurobiological links between depression and AD: the role of TGF-β1 signaling as a new pharmacological target 58
Aflibercept regulates retinal inflammation elicited by high glucose via the PlGF/ERK pathway 56
Therapeutic Challenges of Post-traumatic Stress Disorder: Focus on the Dopaminergic System 56
A new human blood–retinal barrier model based on endothelial cells, pericytes, and astrocytes 55
A water-soluble carbon monoxide-releasing molecule (CORM-3) lowers intraocular pressure in rabbits 54
APP expression in dopamine D3 receptor knock out mice brain during memory consolidation 54
Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach 54
Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems 52
Dopamine D3 receptor, neurofibromin and amyloid precursor protein expression during passive avoidance conditioning 51
Computational systems biology approach to identify novel pharmacological targets for diabetic retinopathy 51
Dopamine outside the brain: The eye, cardiovascular system and endocrine pancreas 51
Dopamine D3 receptor knockout mice exhibit increased hippocampal cAMP response element binding protein (CREB) following acquisition of passive avoidance memory 50
Dopamine D-3 receptor as a new pharmacological target for the treatment of depression 49
The antineoplastic drug flavopiridol reverses memory impairment induced by Amyloid-ß1-42 oligomers in mice 49
null 48
Regulation of intraocular pressure in mice: structural analysis of dopaminergic and serotonergic systems in response to cabergoline 47
Topical ocular delivery of TGF-β1 to the back of the eye: Implications in age-related neurodegenerative diseases 47
Hippocampal neurofibromin and amyloid precursor protein expression in dopamine D3 receptor knock-out mice following passive avoidance conditioning. 45
Genetic blockade of the dopamine D3 receptor enhances hippocampal expression of PACAP and receptors and alters their cortical distribution 45
Oral Echinacea purpurea extract in low-grade, steroid-dependent, autoimmune idiopathic uveitis: a pilot study 44
Beavioral effects of SR 58611A, a beta-3 agonist, on experimental models of mild stress 44
Retinal protection and distribution of curcumin in vitro and in vivo 44
Homology modeling of dopamine D2 and D3 receptors: molecular dynamics refinement and docking evaluation 43
Fortified extract of red berry, Ginkgo biloba, and white willow bark in experimental early diabetic retinopathy 43
Identification of Dysregulated microRNA Networks in Schwann Cell-Like Cultures Exposed to Immune Challenge: Potential Crosstalk with the Protective VIP/PACAP Neuropeptide System 43
TGF-β1 prevents rat retinal insult induced by amyloid-β (1–42) oligomers 43
Dopamine, cognitive impairments and second-generation antipsychotics: From mechanistic advances to more personalized treatments 43
Influence of inulin on plasma isoflavone concentrations in healthy postmenopausal women 42
Fluoxetine prevents Aβ1-42-induced toxicity via a paracrine signaling mediated by transforming-growth-factor-β1 41
Antioxidant Activity of Fluoxetine and Vortioxetine in a Non-Transgenic Animal Model of Alzheimer’s Disease 41
Dopamine D3 receptor, neurofibromin and amyloid precursor protein expression during learning 40
Behavioral effects of the β3 adrenoceptor agonist SR58611A: Is it the putative prototype of a new class of antidepressant/anxiolytic drugs? 40
Dopamine-3 receptor modulates intraocular pressure: implications for glaucoma 39
Epigenetic drugs for Alzheimer's disease: hopes and challenges 39
Anxiolytic effects in mice of a dual blocker of fatty acid amide hydrolase and transient receptor potential vanilloid type-1 channels 39
Cognitive effects of SL65.0155, a serotonin 5-HT4 receptor partial agonist, in animal models of amnesia 39
Behavioral modifications induced by dietary cholesterol in rats 38
Behavioral effects of saredutant, a tachykinin NK2 receptor antagonist, in experimental models of mood disorders under basal and stress-related conditions 38
In vivo evidence that constitutive activity of serotonin2C receptors in the medial prefrontal cortex participates in the control of dopamine release in the rat nucleus accumbens: differential effects of inverse agonist versus antagonist 37
Clinical pharmacology of novel anti-Alzheimer disease modifying medications. 37
Flavopiridol, an inhibitor of cyclin-dependent kinase 4, reverses cognitive deficits induced by β-amyloid peptide 1–42 37
Involvement of NK2 receptors in experimental models of anxiety and depression under basal and stress-related conditions 37
The beta3 adrenoceptor agonist, amibegron (SR58611A) counteracts stress-induced behavioral and neurochemical changes 37
Dopamine D(3) receptor knock-out mice exhibit increased behavioral sensitivity to the anxiolytic drug diazepam 36
New pharmacological strategies for treatment of Alzheimer’s disease: focus on disease-modifying drugs 36
Physiological and therapeutic relevance of constitutive activity at 5HT2C receptors 36
Dopamine D3 receptor-dependent changes in alpha6 GABAA subunit expression in striatum modulate anxiety-like behaviour: Responsiveness and tolerance to diazepam 36
Molecular basis of alcohol intake: role of D3 dopaminergic receptor 36
dopamine d3 receptor, neurofi bromin and amyloid precursor protein expression during learning 36
Effects of citalopram combined with memantine in forced swimming test in rats 36
Polyphenols and neuroprotection: Therapeutic implications for cognitive decline 36
Cannabinoid CB1 receptor blockade effects memory capacity of dopamine D3 KO mice pre-treated with β-amyloid peptide 35
Flavopiridol, an inhibitor of cyclin-dependent kinase 4, reverses cognitive deficits induced by β-amyloid peptide 1–42 34
Enhanced expression of PACAP and of its high affinity receptor (PAC1) in the hippocampus and cerebral cortex of dopamine D3 knockout mice. 34
Molecular Effects of Chronic Exposure to Palmitate in Intestinal Organoids: A New Model to Study Obesity and Diabetes 33
Gut microbiota alterations promote traumatic stress susceptibility associated with p-cresol-induced dopaminergic dysfunctions 33
Serotonin(2C) receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens 33
Effects of Topical Fucosyl-Lactose, a Milk Oligosaccharide, on Dry Eye Model: An Example of Nutraceutical Candidate 33
Dopamine D3 receptor is necessary for ethanol consumption: an approach with buspirone 33
Increased hippocampal CREB phosphorylation in dopamine D3 receptor knockout mice following passive avoidance conditioning. 33
New drugs in psychiatry: Focus on new pharmacological targets 33
Increased sensitivity to antidepressants of D(3) dopamine receptor-deficient mice in the forced swim test (FST) 32
Effects Of COOH-terminal tripeptide alpha-MSH (11-13) on corneal epithelial wound healing:role of nitric oxide 32
Parkin expression profile in dopamine d3 receptor knock-out mice brains 32
Enhanced expression of PACAP and of its high affinity receptor (PAC1) in the hippocampus and cerebral cortex of dopamine D3 knockout mice 32
Dysregulation of miR-15a-5p, miR-497a-5p and miR-511-5p Is Associated with Modulation of BDNF and FKBP5 in Brain Areas of PTSD-Related Susceptible and Resilient Mice 32
Dopamine D3 Receptor, Cognition and Cognitive Dysfunctions in Neuropsychiatric Disorders: From the Bench to the Bedside 31
Dopamine D3 receptor modulates tissue type plasminogen activator (tPA) activity in mouse brain 31
Amnesia induced by beta-amyloid peptide in dopamine D3 knock-out (KO) mice Is affectedby a cannabinoid CB1 receptor antagonist 31
Tackling dipeptidyl peptidase IV in neurological disorders 31
International union of basic and clinical pharmacology CIV: The neurobiology of treatment-resistant depression: From antidepressant classifications to novel pharmacological targets 31
Dopamine-3 Receptor Modulates Intraocular Pressure 29
Role of the endocannabinoid system and vanilloid TRPV1 channels in the phenotype of dopamine D3 receptor knock-out mice 28
Parkin expression in dopamine D3 receptor knock out mice 28
Memory performance of dopamine D3 knock-out mice (KO) mice pre-treated with beta-amyloid peptide is affected by cannabinoid CB1 receptor antagonist 28
Cognitive effects of SL65.0155, a serotonin 5-HT4 receptor partial agonist, in animal models of amnesia 28
Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats. 28
The amnesic effects induced by β-amyloidfragment 1–42 involve cannabinoid neurotransmission in the brain 28
Pharmacological induction of heme oxygenase-1 protects hippocampal interneurons and inhibits inducible nitric oxide synthase following cerebral ischemia reperfusion injury 27
Effects of COOH–Terminal Tripeptide –MSH11–13 on Corneal Epithelial Wound Healing: Role of Nitric Oxide 27
Neurofibromin and amyloid precursor protein expression in dopamine d3 receptor knock-out mice brains 26
The beta3 adrenoceptor agonist amibegron counteracts stress-induced behavioural and neurobiological changes 26
High Glucose Exposure Impairs L-Cell Differentiation in Intestinal Organoids: Molecular Mechanisms and Clinical Implications 26
Enhanced cognitive performance of dopamine D3 receptor "knock-out" mice in the step-through passive-avoidance test: assessing the role of the endocannabinoid/endovanilloid systems 25
D3 dopamine receptor knockout mice: behavioral alteration in experimental models of anxiety 24
Dopamine: an immune transmitter 24
Totale 4.852
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Categoria #
all - tutte 16.111
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 16.111
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019121 0 0 0 0 0 0 0 0 0 0 32 89
2019/20201.197 257 104 167 130 152 94 86 17 58 25 66 41
2020/2021685 23 45 79 8 159 29 131 5 70 22 70 44
2021/2022926 109 120 18 18 147 48 122 29 69 7 41 198
2022/20231.536 123 101 22 179 154 229 17 282 354 7 43 25
2023/2024505 45 82 50 35 24 174 10 55 3 27 0 0
Totale 5.293