IRIS
LEGGIO, GIAN MARCO
 Distribuzione geografica
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Continente #
NA - Nord America 4.307
EU - Europa 2.145
AS - Asia 1.664
SA - Sud America 325
AF - Africa 220
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 4
Totale 8.670
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Nazione #
US - Stati Uniti d'America 4.155
IT - Italia 1.050
SG - Singapore 777
CN - Cina 641
IE - Irlanda 391
BR - Brasile 297
UA - Ucraina 219
CA - Canada 138
CI - Costa d'Avorio 134
RU - Federazione Russa 116
DE - Germania 90
KR - Corea 64
SN - Senegal 63
SE - Svezia 42
GB - Regno Unito 36
NL - Olanda 36
VN - Vietnam 34
FR - Francia 31
FI - Finlandia 30
IN - India 27
BE - Belgio 25
BD - Bangladesh 15
CH - Svizzera 15
JP - Giappone 14
PL - Polonia 14
ES - Italia 13
TR - Turchia 12
ZA - Sudafrica 12
IQ - Iraq 11
IR - Iran 11
LB - Libano 11
AT - Austria 9
UZ - Uzbekistan 9
PK - Pakistan 7
CO - Colombia 6
EC - Ecuador 6
GR - Grecia 6
MX - Messico 6
CZ - Repubblica Ceca 5
HK - Hong Kong 5
LT - Lituania 5
SA - Arabia Saudita 5
AR - Argentina 4
EU - Europa 4
JM - Giamaica 4
VE - Venezuela 4
AE - Emirati Arabi Uniti 3
AZ - Azerbaigian 3
BG - Bulgaria 3
DZ - Algeria 3
JO - Giordania 3
NP - Nepal 3
NZ - Nuova Zelanda 3
AU - Australia 2
BO - Bolivia 2
KE - Kenya 2
PY - Paraguay 2
TW - Taiwan 2
UY - Uruguay 2
AL - Albania 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
CL - Cile 1
CR - Costa Rica 1
DK - Danimarca 1
EG - Egitto 1
ET - Etiopia 1
HN - Honduras 1
IL - Israele 1
KG - Kirghizistan 1
KZ - Kazakistan 1
LK - Sri Lanka 1
LU - Lussemburgo 1
LV - Lettonia 1
MA - Marocco 1
NI - Nicaragua 1
NO - Norvegia 1
OM - Oman 1
PE - Perù 1
PT - Portogallo 1
RO - Romania 1
SM - San Marino 1
TG - Togo 1
TH - Thailandia 1
TT - Trinidad e Tobago 1
TZ - Tanzania 1
Totale 8.670
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Città #
Santa Clara 830
Houston 586
Chandler 469
Singapore 460
Dublin 386
Catania 305
Jacksonville 296
Chicago 273
Boardman 168
Hefei 142
Abidjan 134
Ashburn 111
Andover 104
Cambridge 103
Lawrence 102
Toronto 93
Nanjing 88
Beijing 74
Messina 74
Civitanova Marche 73
Des Moines 65
Seoul 64
Dakar 63
Dallas 54
Council Bluffs 45
Los Angeles 43
Wilmington 43
Florence 41
Ottawa 34
Shenyang 32
The Dalles 32
Hebei 30
Bremen 27
Columbus 27
Saint Petersburg 27
San Mateo 27
Changsha 26
Munich 26
Amsterdam 25
Jiaxing 25
Palermo 24
Nanchang 23
Falls Church 22
Tianjin 22
Dong Ket 21
Rome 21
São Paulo 19
Kraainem 16
Seattle 16
New York 15
Brooklyn 13
Dearborn 13
Grafing 13
Guangzhou 13
Helsinki 13
Jinan 13
Milan 13
Rio de Janeiro 12
Washington 11
Redwood City 10
Zhengzhou 10
Aci Catena 9
Brussels 9
Johannesburg 9
Naples 9
Tokyo 9
Mascalucia 8
Padova 8
Paternò 8
Warsaw 8
Belo Horizonte 7
Curitiba 7
Irvine 7
Misterbianco 7
Moscow 7
Ningbo 7
Providence 7
Pune 7
San Francisco 7
Shanghai 7
Turku 7
Caltanissetta 6
Campinas 6
Hanoi 6
Lappeenranta 6
Liberty Lake 6
London 6
Phoenix 6
Taizhou 6
Vicenza 6
Baghdad 5
Brasília 5
Dhaka 5
Erbil 5
Hangzhou 5
Kunming 5
Nuremberg 5
Siracusa 5
Tappahannock 5
Amiens 4
Totale 6.217
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Nome #
Dopamine D3 receptor deletion increases tissue plasminogen activator (tPA) activity in prefrontal cortex and hippocampus. 529
Current drug treatments targeting dopamine D3 receptor 177
A novel arousal-based individual screening reveals susceptibility and resilience to PTSD-like phenotypes in mice 176
Dopaminergic-GABAergic interplay and alcohol binge drinking 162
Fluoxetine and Vortioxetine Reverse Depressive-Like Phenotype and Memory Deficits Induced by Aβ1-42 Oligomers in Mice: A Key Role of Transforming Growth Factor-β1 126
The epistatic interaction between the dopamine D3 receptor and dysbindin-1 modulates higher-order cognitive functions in mice and humans 122
Sulodexide prevents activation of the PLA2/COX-2/VEGF inflammatory pathway in human retinal endothelial cells by blocking the effect of AGE/RAGE 118
Blockade of dopamine D3 receptors improves hippocampal synaptic function and rescues age‐related cognitive phenotype 110
Retinal biomarkers and pharmacological targets for Hermansky-Pudlak syndrome 7 109
Buspirone counteracts MK-801-induced schizophrenia-like phenotypes through dopamine D3receptor blockade 104
Identification of Dysregulated microRNA Networks in Schwann Cell-Like Cultures Exposed to Immune Challenge: Potential Crosstalk with the Protective VIP/PACAP Neuropeptide System 104
Computational systems biology approach to identify novel pharmacological targets for diabetic retinopathy 103
Anthocyanin Effects on Vascular and Endothelial Health: Evidence from Clinical Trials and Role of Gut Microbiota Metabolites 101
The antineoplastic drug flavopiridol reverses memory impairment induced by Amyloid-ß1-42 oligomers in mice 101
Antioxidant Activity of Fluoxetine and Vortioxetine in a Non-Transgenic Animal Model of Alzheimer’s Disease 100
Pharmacological enhancement of cholinergic neurotransmission alleviates neuroinflammation and improves functional outcomes in a triple transgenic mouse model of Alzheimer’s disease 98
Behavioral and neurochemical changes induced by stress-related conditions are counteracted by the neurokinin-2 receptor antagonist saredutant 98
Epigenetic drugs for Alzheimer's disease: hopes and challenges 98
L'uso dell'acido alfa-lipoico in neurologia 98
Blood-retinal barrier protection against high glucose damage: The role of P2X7 receptor 98
A new human blood–retinal barrier model based on endothelial cells, pericytes, and astrocytes 96
A water-soluble carbon monoxide-releasing molecule (CORM-3) lowers intraocular pressure in rabbits 94
The beta3 adrenoceptor agonist, amibegron (SR58611A) counteracts stress-induced behavioral and neurochemical changes 93
Neurobiological links between depression and AD: the role of TGF-β1 signaling as a new pharmacological target 91
P2X7 receptor antagonism: implications in diabetic retinopathy 90
Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems 89
Aflibercept regulates retinal inflammation elicited by high glucose via the PlGF/ERK pathway 87
APP expression in dopamine D3 receptor knock out mice brain during memory consolidation 81
Dopamine D3 Receptor, Cognition and Cognitive Dysfunctions in Neuropsychiatric Disorders: From the Bench to the Bedside 80
Gut microbiota alterations promote traumatic stress susceptibility associated with p-cresol-induced dopaminergic dysfunctions 78
Regulation of intraocular pressure in mice: structural analysis of dopaminergic and serotonergic systems in response to cabergoline 78
Therapeutic Challenges of Post-traumatic Stress Disorder: Focus on the Dopaminergic System 78
Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach 78
Genetic blockade of the dopamine D3 receptor enhances hippocampal expression of PACAP and receptors and alters their cortical distribution 77
Dysregulation of miR-15a-5p, miR-497a-5p and miR-511-5p Is Associated with Modulation of BDNF and FKBP5 in Brain Areas of PTSD-Related Susceptible and Resilient Mice 77
Molecular Effects of Chronic Exposure to Palmitate in Intestinal Organoids: A New Model to Study Obesity and Diabetes 76
Dopamine D-3 receptor as a new pharmacological target for the treatment of depression 76
Topical ocular delivery of TGF-β1 to the back of the eye: Implications in age-related neurodegenerative diseases 76
Retinal protection and distribution of curcumin in vitro and in vivo 76
Dopamine outside the brain: The eye, cardiovascular system and endocrine pancreas 76
Homology modeling of dopamine D2 and D3 receptors: molecular dynamics refinement and docking evaluation 75
PLGA-PEG NANOPARTICLES LOADED WITH ANTIPSYCHOTIC AGENTS: INFLUENCE OF DRUG MOLECULES ON THE CRYOPROTECTIVE EFFECT OF SUCROSE. 75
Behavioral effects of saredutant, a tachykinin NK2 receptor antagonist, in experimental models of mood disorders under basal and stress-related conditions 73
Behavioral effects of the β3 adrenoceptor agonist SR58611A: Is it the putative prototype of a new class of antidepressant/anxiolytic drugs? 73
Dopamine, cognitive impairments and second-generation antipsychotics: From mechanistic advances to more personalized treatments 73
The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis 72
Hippocampal neurofibromin and amyloid precursor protein expression in dopamine D3 receptor knock-out mice following passive avoidance conditioning. 72
Dopamine-3 receptor modulates intraocular pressure: implications for glaucoma 72
Fortified extract of red berry, Ginkgo biloba, and white willow bark in experimental early diabetic retinopathy 71
Dopamine D3 receptor, neurofibromin and amyloid precursor protein expression during learning 71
Beavioral effects of SR 58611A, a beta-3 agonist, on experimental models of mild stress 71
TGF-β1 prevents rat retinal insult induced by amyloid-β (1–42) oligomers 71
Fluoxetine prevents Aβ1-42-induced toxicity via a paracrine signaling mediated by transforming-growth-factor-β1 69
Cognitive effects of SL65.0155, a serotonin 5-HT4 receptor partial agonist, in animal models of amnesia 69
Polyphenols and neuroprotection: Therapeutic implications for cognitive decline 69
Anxiolytic effects in mice of a dual blocker of fatty acid amide hydrolase and transient receptor potential vanilloid type-1 channels 68
Oral Echinacea purpurea extract in low-grade, steroid-dependent, autoimmune idiopathic uveitis: a pilot study 66
Dopamine D3 receptor knockout mice exhibit increased hippocampal cAMP response element binding protein (CREB) following acquisition of passive avoidance memory 66
Dopamine D3 receptor-dependent changes in alpha6 GABAA subunit expression in striatum modulate anxiety-like behaviour: Responsiveness and tolerance to diazepam 66
Behavioral modifications induced by dietary cholesterol in rats 66
The Role of Dopamine D3 Receptors, Dysbindin, and Their Functional Interaction in the Expression of Key Genes for Neuroplasticity and Neuroinflammation in the Mouse Brain 65
Influence of inulin on plasma isoflavone concentrations in healthy postmenopausal women 65
Cannabinoid CB1 receptor blockade effects memory capacity of dopamine D3 KO mice pre-treated with β-amyloid peptide 64
Clinical pharmacology of novel anti-Alzheimer disease modifying medications. 64
Long-lasting rescue of schizophrenia-relevant cognitive impairments via risperidone-loaded microPlates 63
Amnesia induced by beta-amyloid peptide in dopamine D3 knock-out (KO) mice Is affectedby a cannabinoid CB1 receptor antagonist 62
Flavopiridol, an inhibitor of cyclin-dependent kinase 4, reverses cognitive deficits induced by β-amyloid peptide 1–42 62
Dopamine D(3) receptor knock-out mice exhibit increased behavioral sensitivity to the anxiolytic drug diazepam 61
New pharmacological strategies for treatment of Alzheimer’s disease: focus on disease-modifying drugs 61
Enhanced expression of PACAP and of its high affinity receptor (PAC1) in the hippocampus and cerebral cortex of dopamine D3 knockout mice. 61
High Glucose Exposure Impairs L-Cell Differentiation in Intestinal Organoids: Molecular Mechanisms and Clinical Implications 61
Cortico-cortical transfer of socially derived information gates emotion recognition 60
Dopamine D3 receptor is necessary for ethanol consumption: an approach with buspirone 60
Effects of Topical Fucosyl-Lactose, a Milk Oligosaccharide, on Dry Eye Model: An Example of Nutraceutical Candidate 59
Involvement of NK2 receptors in experimental models of anxiety and depression under basal and stress-related conditions 58
Serotonin(2C) receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens 57
Molecular basis of alcohol intake: role of D3 dopaminergic receptor 57
Enhanced expression of PACAP and of its high affinity receptor (PAC1) in the hippocampus and cerebral cortex of dopamine D3 knockout mice 57
Sex dimorphism controls dysbindin-related cognitive dysfunctions in mice and humans with the contribution of COMT 56
Physiological and therapeutic relevance of constitutive activity at 5HT2C receptors 55
Effects of citalopram combined with memantine in forced swimming test in rats 55
Increased hippocampal CREB phosphorylation in dopamine D3 receptor knockout mice following passive avoidance conditioning. 55
Neurofibromin and amyloid precursor protein expression in dopamine d3 receptor knock-out mice brains 54
In vivo evidence that constitutive activity of serotonin2C receptors in the medial prefrontal cortex participates in the control of dopamine release in the rat nucleus accumbens: differential effects of inverse agonist versus antagonist 53
Effects Of COOH-terminal tripeptide alpha-MSH (11-13) on corneal epithelial wound healing:role of nitric oxide 53
Parkin expression profile in dopamine d3 receptor knock-out mice brains 53
New drugs in psychiatry: Focus on new pharmacological targets 52
Increased sensitivity to antidepressants of D(3) dopamine receptor-deficient mice in the forced swim test (FST) 51
Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats. 51
Tackling dipeptidyl peptidase IV in neurological disorders 51
Role of the endocannabinoid system and vanilloid TRPV1 channels in the phenotype of dopamine D3 receptor knock-out mice 50
Memory performance of dopamine D3 knock-out mice (KO) mice pre-treated with beta-amyloid peptide is affected by cannabinoid CB1 receptor antagonist 50
Dopamine D3 receptor modulates tissue type plasminogen activator (tPA) activity in mouse brain 50
D3 dopamine receptor knockout mice: behavioral alteration in experimental models of anxiety 49
The amnesic effects induced by β-amyloidfragment 1–42 involve cannabinoid neurotransmission in the brain 49
International union of basic and clinical pharmacology CIV: The neurobiology of treatment-resistant depression: From antidepressant classifications to novel pharmacological targets 49
Effects of COOH–Terminal Tripeptide –MSH11–13 on Corneal Epithelial Wound Healing: Role of Nitric Oxide 48
Cognitive effects of SL65.0155, a serotonin 5-HT4 receptor partial agonist, in animal models of amnesia 48
The beta3 adrenoceptor agonist amibegron counteracts stress-induced behavioural and neurobiological changes 48
Dysbindin-1A modulation of astrocytic dopamine and basal ganglia dependent behaviors relevant to schizophrenia 47
Totale 8.011
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Categoria #
all - tutte 32.784
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 32.784
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021630 0 41 75 8 146 28 128 4 67 22 67 44
2021/2022858 102 112 15 18 135 45 114 27 63 7 34 186
2022/20231.427 116 92 18 163 143 215 17 264 327 6 41 25
2023/2024674 44 80 42 33 24 166 10 54 3 22 118 78
2024/20253.136 58 441 154 243 699 435 115 155 222 222 212 180
2025/2026595 348 247 0 0 0 0 0 0 0 0 0 0
Totale 8.926