IRIS
LEGGIO, GIAN MARCO
 Distribuzione geografica
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Continente #
NA - Nord America 6.119
EU - Europa 3.485
AS - Asia 2.960
SA - Sud America 538
AF - Africa 398
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 6
Totale 13.512
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Nazione #
US - Stati Uniti d'America 5.908
SG - Singapore 1.459
IT - Italia 1.234
RU - Federazione Russa 1.005
CN - Cina 820
BR - Brasile 462
IE - Irlanda 392
VN - Vietnam 238
UA - Ucraina 228
CI - Costa d'Avorio 215
CA - Canada 163
FR - Francia 146
KR - Corea 102
DE - Germania 101
GB - Regno Unito 77
IN - India 67
SN - Senegal 64
NG - Nigeria 55
NL - Olanda 50
SE - Svezia 49
FI - Finlandia 36
HK - Hong Kong 34
ES - Italia 31
PL - Polonia 30
BD - Bangladesh 29
MX - Messico 28
BE - Belgio 26
JP - Giappone 25
TR - Turchia 25
ZA - Sudafrica 24
ID - Indonesia 23
IQ - Iraq 22
AR - Argentina 21
CH - Svizzera 16
PK - Pakistan 16
IR - Iran 13
UZ - Uzbekistan 13
CO - Colombia 11
EC - Ecuador 11
KE - Kenya 11
LB - Libano 11
AT - Austria 10
BJ - Benin 10
LT - Lituania 10
VE - Venezuela 10
AZ - Azerbaigian 8
GR - Grecia 8
SA - Arabia Saudita 8
JM - Giamaica 7
AE - Emirati Arabi Uniti 6
CZ - Repubblica Ceca 6
DZ - Algeria 6
JO - Giordania 6
PH - Filippine 6
BO - Bolivia 5
CL - Cile 5
KZ - Kazakistan 5
PY - Paraguay 5
BG - Bulgaria 4
CR - Costa Rica 4
EU - Europa 4
IL - Israele 4
PE - Perù 4
SI - Slovenia 4
TH - Thailandia 4
TN - Tunisia 4
UY - Uruguay 4
AL - Albania 3
AU - Australia 3
BA - Bosnia-Erzegovina 3
DO - Repubblica Dominicana 3
EG - Egitto 3
NP - Nepal 3
NZ - Nuova Zelanda 3
QA - Qatar 3
RO - Romania 3
DK - Danimarca 2
HR - Croazia 2
KG - Kirghizistan 2
LK - Sri Lanka 2
MA - Marocco 2
MD - Moldavia 2
NI - Nicaragua 2
PT - Portogallo 2
TW - Taiwan 2
XK - ???statistics.table.value.countryCode.XK??? 2
AM - Armenia 1
AO - Angola 1
BH - Bahrain 1
ET - Etiopia 1
HN - Honduras 1
HU - Ungheria 1
LU - Lussemburgo 1
LV - Lettonia 1
NO - Norvegia 1
OM - Oman 1
PA - Panama 1
PR - Porto Rico 1
SM - San Marino 1
SY - Repubblica araba siriana 1
Totale 13.509
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Città #
Singapore 847
Santa Clara 844
Dallas 833
Houston 590
Chandler 469
Moscow 432
Dublin 387
Catania 332
San Jose 330
Jacksonville 295
Ashburn 277
Chicago 276
Abidjan 215
Boardman 167
Hefei 151
Beijing 129
Lauterbourg 105
Andover 103
Cambridge 102
Seoul 102
Lawrence 101
Los Angeles 98
Toronto 96
Nanjing 88
Messina 81
Council Bluffs 75
Civitanova Marche 72
New York 70
Ho Chi Minh City 66
Des Moines 65
Dakar 64
Hanoi 50
Florence 43
Wilmington 42
Palermo 39
São Paulo 37
Ottawa 34
Amsterdam 33
Shenyang 32
The Dalles 32
Hebei 30
Rome 30
Hong Kong 29
Lagos 29
Columbus 28
Bremen 27
Munich 27
Saint Petersburg 27
San Mateo 27
Orem 26
Changsha 25
Jiaxing 25
Tianjin 23
Warsaw 23
Falls Church 22
Nanchang 22
Dong Ket 21
Montreal 21
Brooklyn 20
Buffalo 20
Tokyo 20
Abuja 19
Milan 19
Seattle 19
Denver 18
Johannesburg 18
Rio de Janeiro 18
Kraainem 16
Helsinki 15
Guangzhou 14
Poplar 14
Chennai 13
Dearborn 13
Grafing 13
Haiphong 13
Jakarta 13
Jinan 13
Atlanta 12
Phoenix 11
Washington 11
Baghdad 10
Belo Horizonte 10
Brussels 10
Cotonou 10
Curitiba 10
Lappeenranta 10
London 10
Redwood City 10
Zhengzhou 10
Aci Catena 9
Brasília 9
Mascalucia 9
Naples 9
San Francisco 9
Ankara 8
Mexico City 8
Paternò 8
Pune 8
Shanghai 8
Baku 7
Totale 9.190
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Nome #
Dopamine D3 receptor deletion increases tissue plasminogen activator (tPA) activity in prefrontal cortex and hippocampus. 561
A novel arousal-based individual screening reveals susceptibility and resilience to PTSD-like phenotypes in mice 288
Current drug treatments targeting dopamine D3 receptor 239
Dopaminergic-GABAergic interplay and alcohol binge drinking 232
Fluoxetine and Vortioxetine Reverse Depressive-Like Phenotype and Memory Deficits Induced by Aβ1-42 Oligomers in Mice: A Key Role of Transforming Growth Factor-β1 217
Blockade of dopamine D3 receptors improves hippocampal synaptic function and rescues age‐related cognitive phenotype 199
Antioxidant Activity of Fluoxetine and Vortioxetine in a Non-Transgenic Animal Model of Alzheimer’s Disease 184
A new human blood–retinal barrier model based on endothelial cells, pericytes, and astrocytes 179
The epistatic interaction between the dopamine D3 receptor and dysbindin-1 modulates higher-order cognitive functions in mice and humans 177
Buspirone counteracts MK-801-induced schizophrenia-like phenotypes through dopamine D3receptor blockade 175
Anthocyanin Effects on Vascular and Endothelial Health: Evidence from Clinical Trials and Role of Gut Microbiota Metabolites 172
Pharmacological enhancement of cholinergic neurotransmission alleviates neuroinflammation and improves functional outcomes in a triple transgenic mouse model of Alzheimer’s disease 168
Sulodexide prevents activation of the PLA2/COX-2/VEGF inflammatory pathway in human retinal endothelial cells by blocking the effect of AGE/RAGE 166
Blood-retinal barrier protection against high glucose damage: The role of P2X7 receptor 162
The antineoplastic drug flavopiridol reverses memory impairment induced by Amyloid-ß1-42 oligomers in mice 160
Computational systems biology approach to identify novel pharmacological targets for diabetic retinopathy 160
A water-soluble carbon monoxide-releasing molecule (CORM-3) lowers intraocular pressure in rabbits 159
Neurobiological links between depression and AD: the role of TGF-β1 signaling as a new pharmacological target 158
Aflibercept regulates retinal inflammation elicited by high glucose via the PlGF/ERK pathway 155
Behavioral and neurochemical changes induced by stress-related conditions are counteracted by the neurokinin-2 receptor antagonist saredutant 148
Gut microbiota alterations promote traumatic stress susceptibility associated with p-cresol-induced dopaminergic dysfunctions 146
Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems 141
Dysregulation of miR-15a-5p, miR-497a-5p and miR-511-5p Is Associated with Modulation of BDNF and FKBP5 in Brain Areas of PTSD-Related Susceptible and Resilient Mice 141
Dopamine D3 Receptor, Cognition and Cognitive Dysfunctions in Neuropsychiatric Disorders: From the Bench to the Bedside 139
Retinal biomarkers and pharmacological targets for Hermansky-Pudlak syndrome 7 137
Behavioral effects of the β3 adrenoceptor agonist SR58611A: Is it the putative prototype of a new class of antidepressant/anxiolytic drugs? 136
Beavioral effects of SR 58611A, a beta-3 agonist, on experimental models of mild stress 135
Sex dimorphism controls dysbindin-related cognitive dysfunctions in mice and humans with the contribution of COMT 130
Anxiolytic effects in mice of a dual blocker of fatty acid amide hydrolase and transient receptor potential vanilloid type-1 channels 130
Identification of Dysregulated microRNA Networks in Schwann Cell-Like Cultures Exposed to Immune Challenge: Potential Crosstalk with the Protective VIP/PACAP Neuropeptide System 130
Epigenetic drugs for Alzheimer's disease: hopes and challenges 129
Dopamine D-3 receptor as a new pharmacological target for the treatment of depression 126
Behavioral effects of saredutant, a tachykinin NK2 receptor antagonist, in experimental models of mood disorders under basal and stress-related conditions 126
Molecular Effects of Chronic Exposure to Palmitate in Intestinal Organoids: A New Model to Study Obesity and Diabetes 125
Topical ocular delivery of TGF-β1 to the back of the eye: Implications in age-related neurodegenerative diseases 125
Dopamine D3 receptor-dependent changes in alpha6 GABAA subunit expression in striatum modulate anxiety-like behaviour: Responsiveness and tolerance to diazepam 124
APP expression in dopamine D3 receptor knock out mice brain during memory consolidation 123
The beta3 adrenoceptor agonist, amibegron (SR58611A) counteracts stress-induced behavioral and neurochemical changes 123
Behavioral modifications induced by dietary cholesterol in rats 122
Dopamine D3 receptor is necessary for ethanol consumption: an approach with buspirone 122
Retinal protection and distribution of curcumin in vitro and in vivo 122
Amnesia induced by beta-amyloid peptide in dopamine D3 knock-out (KO) mice Is affectedby a cannabinoid CB1 receptor antagonist 121
L'uso dell'acido alfa-lipoico in neurologia 121
Dopamine, cognitive impairments and second-generation antipsychotics: From mechanistic advances to more personalized treatments 121
Dopamine D3 receptor, neurofibromin and amyloid precursor protein expression during learning 119
Long-lasting rescue of schizophrenia-relevant cognitive impairments via risperidone-loaded microPlates 118
PLGA-PEG NANOPARTICLES LOADED WITH ANTIPSYCHOTIC AGENTS: INFLUENCE OF DRUG MOLECULES ON THE CRYOPROTECTIVE EFFECT OF SUCROSE 117
P2X7 receptor antagonism: implications in diabetic retinopathy 115
Genetic blockade of the dopamine D3 receptor enhances hippocampal expression of PACAP and receptors and alters their cortical distribution 113
Homology modeling of dopamine D2 and D3 receptors: molecular dynamics refinement and docking evaluation 110
Therapeutic Challenges of Post-traumatic Stress Disorder: Focus on the Dopaminergic System 110
Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach 110
High Glucose Exposure Impairs L-Cell Differentiation in Intestinal Organoids: Molecular Mechanisms and Clinical Implications 109
Fluoxetine prevents Aβ1-42-induced toxicity via a paracrine signaling mediated by transforming-growth-factor-β1 108
The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis 107
Dopamine D3 receptor knockout mice exhibit increased hippocampal cAMP response element binding protein (CREB) following acquisition of passive avoidance memory 104
Regulation of intraocular pressure in mice: structural analysis of dopaminergic and serotonergic systems in response to cabergoline 103
Cortico-cortical transfer of socially derived information gates emotion recognition 101
Polyphenols and neuroprotection: Therapeutic implications for cognitive decline 99
Fortified extract of red berry, Ginkgo biloba, and white willow bark in experimental early diabetic retinopathy 98
Dopamine outside the brain: The eye, cardiovascular system and endocrine pancreas 98
Anthocyanin metabolites from gut microbiota and cognitive health 97
Pharmacological and genetic evidence of dopamine receptor 3-mediated vasoconstriction in isolated mouse aorta 97
Effects of Topical Fucosyl-Lactose, a Milk Oligosaccharide, on Dry Eye Model: An Example of Nutraceutical Candidate 97
TGF-β1 prevents rat retinal insult induced by amyloid-β (1–42) oligomers 97
Dopamine-3 receptor modulates intraocular pressure: implications for glaucoma 95
Cognitive effects of SL65.0155, a serotonin 5-HT4 receptor partial agonist, in animal models of amnesia 95
Prenatal stress induces a depressive-like phenotype in adolescent rats: The key role of TGF-β1 pathway 93
Hippocampal neurofibromin and amyloid precursor protein expression in dopamine D3 receptor knock-out mice following passive avoidance conditioning. 93
Role of the endocannabinoid system and vanilloid TRPV1 channels in the phenotype of dopamine D3 receptor knock-out mice 90
Dysbindin-1A modulation of astrocytic dopamine and basal ganglia dependent behaviors relevant to schizophrenia 88
Cannabinoid CB1 receptor blockade effects memory capacity of dopamine D3 KO mice pre-treated with β-amyloid peptide 88
The Role of Dopamine D3 Receptors, Dysbindin, and Their Functional Interaction in the Expression of Key Genes for Neuroplasticity and Neuroinflammation in the Mouse Brain 87
New pharmacological strategies for treatment of Alzheimer’s disease: focus on disease-modifying drugs 87
Oral Echinacea purpurea extract in low-grade, steroid-dependent, autoimmune idiopathic uveitis: a pilot study 85
Enhanced expression of PACAP and of its high affinity receptor (PAC1) in the hippocampus and cerebral cortex of dopamine D3 knockout mice. 85
Tackling dipeptidyl peptidase IV in neurological disorders 85
Dopamine D(3) receptor knock-out mice exhibit increased behavioral sensitivity to the anxiolytic drug diazepam 84
Ultra-Processed Food Consumption and Depressive Symptoms in a Mediterranean Cohort 83
Effects of citalopram combined with memantine in forced swimming test in rats 83
Physiological and therapeutic relevance of constitutive activity at 5HT2C receptors 82
Dopamine D3 receptor modulates tissue type plasminogen activator (tPA) activity in mouse brain 82
New antipsychotic drugs for the treatment of agitation and psychosis in Alzheimer's disease: Focus on brexpiprazole and pimavanserin 82
Influence of inulin on plasma isoflavone concentrations in healthy postmenopausal women 81
Clinical pharmacology of novel anti-Alzheimer disease modifying medications. 81
Acute stress alters recognition memory and AMPA/NMDA receptor subunits in a sex-dependent manner 80
Flavopiridol, an inhibitor of cyclin-dependent kinase 4, reverses cognitive deficits induced by β-amyloid peptide 1–42 80
Effects Of COOH-terminal tripeptide alpha-MSH (11-13) on corneal epithelial wound healing:role of nitric oxide 79
Molecular basis of alcohol intake: role of D3 dopaminergic receptor 79
Involvement of NK2 receptors in experimental models of anxiety and depression under basal and stress-related conditions 79
New drugs in psychiatry: Focus on new pharmacological targets 78
Cognitive effects of SL65.0155, a serotonin 5-HT4 receptor partial agonist, in animal models of amnesia 77
In vivo evidence that constitutive activity of serotonin2C receptors in the medial prefrontal cortex participates in the control of dopamine release in the rat nucleus accumbens: differential effects of inverse agonist versus antagonist 76
Imputed expression of schizophrenia-associated genes and cognitive measures in patients with schizophrenia 75
Increased hippocampal CREB phosphorylation in dopamine D3 receptor knockout mice following passive avoidance conditioning. 75
Increased sensitivity to antidepressants of D(3) dopamine receptor-deficient mice in the forced swim test (FST) 73
Serotonin(2C) receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens 73
D3 dopamine receptor knockout mice: behavioral alteration in experimental models of anxiety 73
Parkin expression profile in dopamine d3 receptor knock-out mice brains 73
Neurofibromin and amyloid precursor protein expression in dopamine d3 receptor knock-out mice brains 72
Totale 12.252
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Categoria #
all - tutte 42.813
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 42.813
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021111 0 0 0 0 0 0 0 0 0 0 67 44
2021/2022851 101 111 15 18 134 45 113 27 63 7 33 184
2022/20231.422 115 92 18 163 143 214 17 263 325 6 41 25
2023/2024671 44 80 42 33 24 165 10 54 3 21 117 78
2024/20253.114 57 436 154 242 694 432 115 154 221 219 212 178
2025/20265.493 346 292 976 425 834 1.161 651 116 356 313 23 0
Totale 13.769