IRIS
LEGGIO, GIAN MARCO
 Distribuzione geografica
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Continente #
NA - Nord America 4.147
EU - Europa 2.120
AS - Asia 1.369
SA - Sud America 288
AF - Africa 214
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 4
Totale 8.147
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Nazione #
US - Stati Uniti d'America 4.002
IT - Italia 1.043
SG - Singapore 714
CN - Cina 482
IE - Irlanda 388
BR - Brasile 264
UA - Ucraina 219
CA - Canada 134
CI - Costa d'Avorio 134
RU - Federazione Russa 116
DE - Germania 88
SN - Senegal 62
SE - Svezia 42
GB - Regno Unito 35
NL - Olanda 35
FI - Finlandia 30
FR - Francia 30
VN - Vietnam 28
BE - Belgio 25
KR - Corea 24
IN - India 20
CH - Svizzera 15
IR - Iran 11
LB - Libano 11
PL - Polonia 11
BD - Bangladesh 10
ES - Italia 10
JP - Giappone 10
TR - Turchia 10
AT - Austria 9
IQ - Iraq 9
UZ - Uzbekistan 9
ZA - Sudafrica 8
EC - Ecuador 6
GR - Grecia 6
CZ - Repubblica Ceca 5
HK - Hong Kong 5
MX - Messico 5
AR - Argentina 4
EU - Europa 4
PK - Pakistan 4
VE - Venezuela 4
AE - Emirati Arabi Uniti 3
AZ - Azerbaigian 3
CO - Colombia 3
DZ - Algeria 3
JM - Giamaica 3
JO - Giordania 3
NP - Nepal 3
NZ - Nuova Zelanda 3
AU - Australia 2
BG - Bulgaria 2
BO - Bolivia 2
LT - Lituania 2
PY - Paraguay 2
SA - Arabia Saudita 2
TW - Taiwan 2
AL - Albania 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
CL - Cile 1
CR - Costa Rica 1
DK - Danimarca 1
EG - Egitto 1
ET - Etiopia 1
IL - Israele 1
KE - Kenya 1
KG - Kirghizistan 1
KZ - Kazakistan 1
LK - Sri Lanka 1
LU - Lussemburgo 1
LV - Lettonia 1
MA - Marocco 1
NI - Nicaragua 1
NO - Norvegia 1
OM - Oman 1
PE - Perù 1
PT - Portogallo 1
RO - Romania 1
SM - San Marino 1
TG - Togo 1
TH - Thailandia 1
TT - Trinidad e Tobago 1
TZ - Tanzania 1
UY - Uruguay 1
Totale 8.147
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Città #
Santa Clara 828
Houston 585
Chandler 469
Singapore 416
Dublin 384
Catania 305
Jacksonville 296
Chicago 270
Boardman 168
Abidjan 134
Andover 104
Cambridge 103
Lawrence 102
Toronto 93
Nanjing 88
Ashburn 81
Messina 74
Civitanova Marche 73
Des Moines 65
Dakar 62
Hefei 48
Council Bluffs 45
Wilmington 43
Florence 41
Ottawa 34
Shenyang 32
The Dalles 32
Hebei 30
Bremen 27
Saint Petersburg 27
San Mateo 27
Changsha 26
Munich 26
Amsterdam 25
Beijing 25
Jiaxing 25
Los Angeles 25
Seoul 24
Columbus 23
Nanchang 23
Rome 23
Falls Church 22
Tianjin 22
Dong Ket 21
Palermo 18
Kraainem 16
Seattle 16
São Paulo 15
Dearborn 13
Grafing 13
Guangzhou 13
Helsinki 13
Jinan 13
Milan 13
Rio de Janeiro 11
Washington 11
New York 10
Redwood City 10
Zhengzhou 10
Aci Catena 9
Brussels 9
Naples 9
Mascalucia 8
Padova 8
Paternò 8
Belo Horizonte 7
Curitiba 7
Irvine 7
Misterbianco 7
Moscow 7
Ningbo 7
Providence 7
Pune 7
Shanghai 7
Turku 7
Brooklyn 6
Caltanissetta 6
Campinas 6
Hanoi 6
Johannesburg 6
Lappeenranta 6
Liberty Lake 6
Taizhou 6
Vicenza 6
Brasília 5
Hangzhou 5
Kunming 5
London 5
Phoenix 5
Siracusa 5
Tappahannock 5
Tokyo 5
Warsaw 5
Amiens 4
Baghdad 4
Barcelona 4
Bronte 4
Den Haag 4
Dhaka 4
Erbil 4
Totale 5.839
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Nome #
Dopamine D3 receptor deletion increases tissue plasminogen activator (tPA) activity in prefrontal cortex and hippocampus. 527
Current drug treatments targeting dopamine D3 receptor 172
A novel arousal-based individual screening reveals susceptibility and resilience to PTSD-like phenotypes in mice 170
Dopaminergic-GABAergic interplay and alcohol binge drinking 156
Fluoxetine and Vortioxetine Reverse Depressive-Like Phenotype and Memory Deficits Induced by Aβ1-42 Oligomers in Mice: A Key Role of Transforming Growth Factor-β1 120
The epistatic interaction between the dopamine D3 receptor and dysbindin-1 modulates higher-order cognitive functions in mice and humans 118
Sulodexide prevents activation of the PLA2/COX-2/VEGF inflammatory pathway in human retinal endothelial cells by blocking the effect of AGE/RAGE 116
Retinal biomarkers and pharmacological targets for Hermansky-Pudlak syndrome 7 106
Buspirone counteracts MK-801-induced schizophrenia-like phenotypes through dopamine D3receptor blockade 102
Computational systems biology approach to identify novel pharmacological targets for diabetic retinopathy 102
Identification of Dysregulated microRNA Networks in Schwann Cell-Like Cultures Exposed to Immune Challenge: Potential Crosstalk with the Protective VIP/PACAP Neuropeptide System 101
Blockade of dopamine D3 receptors improves hippocampal synaptic function and rescues age‐related cognitive phenotype 97
Epigenetic drugs for Alzheimer's disease: hopes and challenges 97
L'uso dell'acido alfa-lipoico in neurologia 97
Behavioral and neurochemical changes induced by stress-related conditions are counteracted by the neurokinin-2 receptor antagonist saredutant 94
Blood-retinal barrier protection against high glucose damage: The role of P2X7 receptor 94
The beta3 adrenoceptor agonist, amibegron (SR58611A) counteracts stress-induced behavioral and neurochemical changes 91
A water-soluble carbon monoxide-releasing molecule (CORM-3) lowers intraocular pressure in rabbits 90
A new human blood–retinal barrier model based on endothelial cells, pericytes, and astrocytes 89
P2X7 receptor antagonism: implications in diabetic retinopathy 88
Neurobiological links between depression and AD: the role of TGF-β1 signaling as a new pharmacological target 87
Antioxidant Activity of Fluoxetine and Vortioxetine in a Non-Transgenic Animal Model of Alzheimer’s Disease 86
Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems 85
Aflibercept regulates retinal inflammation elicited by high glucose via the PlGF/ERK pathway 83
Pharmacological enhancement of cholinergic neurotransmission alleviates neuroinflammation and improves functional outcomes in a triple transgenic mouse model of Alzheimer’s disease 79
The antineoplastic drug flavopiridol reverses memory impairment induced by Amyloid-ß1-42 oligomers in mice 79
APP expression in dopamine D3 receptor knock out mice brain during memory consolidation 78
Genetic blockade of the dopamine D3 receptor enhances hippocampal expression of PACAP and receptors and alters their cortical distribution 76
Therapeutic Challenges of Post-traumatic Stress Disorder: Focus on the Dopaminergic System 76
Dysregulation of miR-15a-5p, miR-497a-5p and miR-511-5p Is Associated with Modulation of BDNF and FKBP5 in Brain Areas of PTSD-Related Susceptible and Resilient Mice 76
Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach 75
PLGA-PEG NANOPARTICLES LOADED WITH ANTIPSYCHOTIC AGENTS: INFLUENCE OF DRUG MOLECULES ON THE CRYOPROTECTIVE EFFECT OF SUCROSE. 74
Dopamine D-3 receptor as a new pharmacological target for the treatment of depression 74
Dopamine outside the brain: The eye, cardiovascular system and endocrine pancreas 74
Anthocyanin Effects on Vascular and Endothelial Health: Evidence from Clinical Trials and Role of Gut Microbiota Metabolites 73
Regulation of intraocular pressure in mice: structural analysis of dopaminergic and serotonergic systems in response to cabergoline 72
Topical ocular delivery of TGF-β1 to the back of the eye: Implications in age-related neurodegenerative diseases 72
Retinal protection and distribution of curcumin in vitro and in vivo 72
Dopamine, cognitive impairments and second-generation antipsychotics: From mechanistic advances to more personalized treatments 71
Behavioral effects of the β3 adrenoceptor agonist SR58611A: Is it the putative prototype of a new class of antidepressant/anxiolytic drugs? 70
Gut microbiota alterations promote traumatic stress susceptibility associated with p-cresol-induced dopaminergic dysfunctions 69
Hippocampal neurofibromin and amyloid precursor protein expression in dopamine D3 receptor knock-out mice following passive avoidance conditioning. 69
Dopamine D3 receptor, neurofibromin and amyloid precursor protein expression during learning 69
Beavioral effects of SR 58611A, a beta-3 agonist, on experimental models of mild stress 69
Behavioral effects of saredutant, a tachykinin NK2 receptor antagonist, in experimental models of mood disorders under basal and stress-related conditions 69
Homology modeling of dopamine D2 and D3 receptors: molecular dynamics refinement and docking evaluation 68
Fortified extract of red berry, Ginkgo biloba, and white willow bark in experimental early diabetic retinopathy 68
Fluoxetine prevents Aβ1-42-induced toxicity via a paracrine signaling mediated by transforming-growth-factor-β1 67
Cognitive effects of SL65.0155, a serotonin 5-HT4 receptor partial agonist, in animal models of amnesia 67
Polyphenols and neuroprotection: Therapeutic implications for cognitive decline 67
TGF-β1 prevents rat retinal insult induced by amyloid-β (1–42) oligomers 66
Dopamine D3 Receptor, Cognition and Cognitive Dysfunctions in Neuropsychiatric Disorders: From the Bench to the Bedside 65
Dopamine-3 receptor modulates intraocular pressure: implications for glaucoma 65
Dopamine D3 receptor knockout mice exhibit increased hippocampal cAMP response element binding protein (CREB) following acquisition of passive avoidance memory 65
Anxiolytic effects in mice of a dual blocker of fatty acid amide hydrolase and transient receptor potential vanilloid type-1 channels 65
Oral Echinacea purpurea extract in low-grade, steroid-dependent, autoimmune idiopathic uveitis: a pilot study 64
Molecular Effects of Chronic Exposure to Palmitate in Intestinal Organoids: A New Model to Study Obesity and Diabetes 63
Behavioral modifications induced by dietary cholesterol in rats 63
The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis 62
Influence of inulin on plasma isoflavone concentrations in healthy postmenopausal women 62
Dopamine D3 receptor-dependent changes in alpha6 GABAA subunit expression in striatum modulate anxiety-like behaviour: Responsiveness and tolerance to diazepam 62
Clinical pharmacology of novel anti-Alzheimer disease modifying medications. 61
New pharmacological strategies for treatment of Alzheimer’s disease: focus on disease-modifying drugs 60
Enhanced expression of PACAP and of its high affinity receptor (PAC1) in the hippocampus and cerebral cortex of dopamine D3 knockout mice. 60
Flavopiridol, an inhibitor of cyclin-dependent kinase 4, reverses cognitive deficits induced by β-amyloid peptide 1–42 60
Dopamine D(3) receptor knock-out mice exhibit increased behavioral sensitivity to the anxiolytic drug diazepam 59
Amnesia induced by beta-amyloid peptide in dopamine D3 knock-out (KO) mice Is affectedby a cannabinoid CB1 receptor antagonist 59
High Glucose Exposure Impairs L-Cell Differentiation in Intestinal Organoids: Molecular Mechanisms and Clinical Implications 59
Serotonin(2C) receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens 57
Effects of Topical Fucosyl-Lactose, a Milk Oligosaccharide, on Dry Eye Model: An Example of Nutraceutical Candidate 57
Involvement of NK2 receptors in experimental models of anxiety and depression under basal and stress-related conditions 57
The Role of Dopamine D3 Receptors, Dysbindin, and Their Functional Interaction in the Expression of Key Genes for Neuroplasticity and Neuroinflammation in the Mouse Brain 56
Cannabinoid CB1 receptor blockade effects memory capacity of dopamine D3 KO mice pre-treated with β-amyloid peptide 56
Molecular basis of alcohol intake: role of D3 dopaminergic receptor 56
Dopamine D3 receptor is necessary for ethanol consumption: an approach with buspirone 56
Long-lasting rescue of schizophrenia-relevant cognitive impairments via risperidone-loaded microPlates 55
Enhanced expression of PACAP and of its high affinity receptor (PAC1) in the hippocampus and cerebral cortex of dopamine D3 knockout mice 55
Neurofibromin and amyloid precursor protein expression in dopamine d3 receptor knock-out mice brains 54
Physiological and therapeutic relevance of constitutive activity at 5HT2C receptors 53
Effects of citalopram combined with memantine in forced swimming test in rats 53
Effects Of COOH-terminal tripeptide alpha-MSH (11-13) on corneal epithelial wound healing:role of nitric oxide 52
Parkin expression profile in dopamine d3 receptor knock-out mice brains 52
Increased hippocampal CREB phosphorylation in dopamine D3 receptor knockout mice following passive avoidance conditioning. 52
In vivo evidence that constitutive activity of serotonin2C receptors in the medial prefrontal cortex participates in the control of dopamine release in the rat nucleus accumbens: differential effects of inverse agonist versus antagonist 51
Increased sensitivity to antidepressants of D(3) dopamine receptor-deficient mice in the forced swim test (FST) 50
Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats. 50
Tackling dipeptidyl peptidase IV in neurological disorders 50
New drugs in psychiatry: Focus on new pharmacological targets 50
Role of the endocannabinoid system and vanilloid TRPV1 channels in the phenotype of dopamine D3 receptor knock-out mice 48
Dopamine D3 receptor modulates tissue type plasminogen activator (tPA) activity in mouse brain 48
The amnesic effects induced by β-amyloidfragment 1–42 involve cannabinoid neurotransmission in the brain 48
Effects of COOH–Terminal Tripeptide –MSH11–13 on Corneal Epithelial Wound Healing: Role of Nitric Oxide 47
Cognitive effects of SL65.0155, a serotonin 5-HT4 receptor partial agonist, in animal models of amnesia 47
D3 dopamine receptor knockout mice: behavioral alteration in experimental models of anxiety 47
International union of basic and clinical pharmacology CIV: The neurobiology of treatment-resistant depression: From antidepressant classifications to novel pharmacological targets 47
Memory performance of dopamine D3 knock-out mice (KO) mice pre-treated with beta-amyloid peptide is affected by cannabinoid CB1 receptor antagonist 46
The beta3 adrenoceptor agonist amibegron counteracts stress-induced behavioural and neurobiological changes 45
Cortico-cortical transfer of socially derived information gates emotion recognition 44
Pharmacological induction of heme oxygenase-1 protects hippocampal interneurons and inhibits inducible nitric oxide synthase following cerebral ischemia reperfusion injury 44
Tin chloride enhances parvalbumin-positive interneuron survival by modulating heme metabolism in a model of cerebral ischemia 43
Totale 7.587
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Categoria #
all - tutte 30.764
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 30.764
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021652 22 41 75 8 146 28 128 4 67 22 67 44
2021/2022858 102 112 15 18 135 45 114 27 63 7 34 186
2022/20231.427 116 92 18 163 143 215 17 264 327 6 41 25
2023/2024674 44 80 42 33 24 166 10 54 3 22 118 78
2024/20253.151 58 441 154 243 699 435 115 155 222 222 219 188
2025/202659 59 0 0 0 0 0 0 0 0 0 0 0
Totale 8.405