PURRELLO, Francesco
 Distribuzione geografica
Continente #
NA - Nord America 14.297
EU - Europa 5.793
AS - Asia 5.178
SA - Sud America 1.397
AF - Africa 918
Continente sconosciuto - Info sul continente non disponibili 12
OC - Oceania 9
Totale 27.604
Nazione #
US - Stati Uniti d'America 13.826
SG - Singapore 2.311
IT - Italia 2.034
CN - Cina 1.828
IE - Irlanda 1.306
BR - Brasile 1.242
UA - Ucraina 1.029
CI - Costa d'Avorio 591
CA - Canada 405
RU - Federazione Russa 324
IN - India 266
VN - Vietnam 256
DE - Germania 242
SE - Svezia 227
SN - Senegal 203
GB - Regno Unito 152
KR - Corea 121
FI - Finlandia 73
NL - Olanda 70
FR - Francia 59
TR - Turchia 56
AR - Argentina 55
BD - Bangladesh 51
PL - Polonia 51
UZ - Uzbekistan 45
JP - Giappone 42
MX - Messico 42
AT - Austria 41
CH - Svizzera 40
ZA - Sudafrica 39
NG - Nigeria 36
HK - Hong Kong 32
EC - Ecuador 28
IQ - Iraq 25
ES - Italia 24
CO - Colombia 23
GR - Grecia 22
CZ - Repubblica Ceca 20
IR - Iran 19
MA - Marocco 19
BE - Belgio 18
LB - Libano 18
PK - Pakistan 18
ID - Indonesia 14
BG - Bulgaria 12
VE - Venezuela 12
EU - Europa 11
CL - Cile 10
LT - Lituania 10
SA - Arabia Saudita 10
AZ - Azerbaigian 9
KE - Kenya 9
PY - Paraguay 9
AL - Albania 8
PE - Perù 8
RO - Romania 7
AU - Australia 6
KW - Kuwait 6
TN - Tunisia 6
AE - Emirati Arabi Uniti 5
HU - Ungheria 5
IL - Israele 5
OM - Oman 5
UY - Uruguay 5
BO - Bolivia 4
DO - Repubblica Dominicana 4
IS - Islanda 4
JO - Giordania 4
KG - Kirghizistan 4
PA - Panama 4
PS - Palestinian Territory 4
TH - Thailandia 4
BH - Bahrain 3
DZ - Algeria 3
HN - Honduras 3
JM - Giamaica 3
KZ - Kazakistan 3
MY - Malesia 3
NP - Nepal 3
NZ - Nuova Zelanda 3
RS - Serbia 3
SV - El Salvador 3
AO - Angola 2
DK - Danimarca 2
EG - Egitto 2
GE - Georgia 2
MD - Moldavia 2
MK - Macedonia 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
AM - Armenia 1
BB - Barbados 1
BN - Brunei Darussalam 1
BS - Bahamas 1
BW - Botswana 1
CD - Congo 1
DM - Dominica 1
EE - Estonia 1
ET - Etiopia 1
GA - Gabon 1
Totale 27.589
Città #
Dallas 2.693
Santa Clara 1.809
Chandler 1.411
Singapore 1.407
Dublin 1.299
Jacksonville 1.079
Chicago 598
Abidjan 591
Boardman 547
Ashburn 403
Cambridge 357
Lawrence 356
Catania 351
Andover 349
Nanjing 346
Hefei 293
Toronto 287
Beijing 285
Civitanova Marche 254
Wilmington 223
Dakar 203
Des Moines 188
Los Angeles 187
Kochi 176
San Mateo 169
Milan 161
Rome 155
Seoul 120
Nanchang 100
São Paulo 99
New York 98
Shenyang 95
Padova 88
Hebei 86
Houston 82
The Dalles 78
Ho Chi Minh City 72
Saint Petersburg 72
Dong Ket 67
Jiaxing 67
Ottawa 67
Columbus 61
Munich 60
Bremen 55
Palermo 55
Council Bluffs 51
Changsha 49
Grafing 45
Tianjin 44
Rio de Janeiro 41
Tokyo 40
Hanoi 39
Warsaw 38
Brooklyn 35
San Francisco 35
Abuja 34
Belo Horizonte 33
Montreal 33
Moscow 32
Naples 30
Brasília 29
Helsinki 29
Seattle 29
Hong Kong 27
Lappeenranta 27
Boston 25
Istanbul 24
Phoenix 24
Stockholm 24
Denver 23
Messina 23
Pune 23
Redondo Beach 23
Washington 22
Atlanta 21
Johannesburg 21
London 21
Buffalo 20
Den Haag 20
Augusta 19
Boydton 19
Kunming 19
Norwalk 19
Amsterdam 18
Carrara 18
Chennai 17
Orem 17
Poplar 17
Porto Alegre 17
Tashkent 17
Turku 17
Campinas 16
Jinan 15
Leawood 15
Salvador 14
Ardabil 13
Bari 13
Curitiba 13
Guayaquil 13
Mexico City 13
Totale 18.972
Nome #
IL DIABETE MELLITO AUMENTA LE RESISTENZE ARTERIOSE RENALI NEI PAZIENTI CON CIRROSI EPATICA 697
Long-term preservation of kidney function with SGLT-2 inhibitors versus comparator drugs in people with type 2 diabetes and chronic kidney disease 364
Criteri IDF e ATP-III per la diagnosi di sindrome metabolica: relazione con la prevalenza di steatosi epatica 242
1 h Postload Glycemia Is Associated with Low Endogenous Secretory Receptor for Advanced Glycation End Product Levels and Early Markers of Cardiovascular Disease 197
Adherence to antithrombotic therapy guidelines improves mortality among elderly patients with atrial fibrillation: insights from the REPOSI study 170
Critical appraisal of the European Union Scientific Committee on Health, Environmental, and Emergency Risks (SCHEER) Preliminary Opinion on electronic cigarettes 150
The impact of SLCO1B1 rs4149056 on LDL-C target achievement after lipid lowering therapy optimization in men and women with familial hypercholesterolemia 142
An Uncharacterised lncRNA Coded by the ASAP1 Locus Is Downregulated in Serum of Type 2 Diabetes Mellitus Patients 135
Il Rasario. Semeiotica medica 135
Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department 132
Polypharmacy in older people: lessons from 10 years of experience with the REPOSI register 130
Chronic exposure to palmitate impairs insulin signaling in an intestinal L-cell line: A possible shift from GLP-1 to glucagon production 128
A ten-year (1989-1998) perspective study of the incidence of Type 1 diabetes in the district of Catania (Sicily) in a 0-14 year age group 126
Antihypertensive treatment changes and related clinical outcomes in older hospitalized patients 122
COPPER ADDITION PREVENTS THE INHIBITORY EFFECTS OF INTERLEUKIN-1-BETA ON RAT PANCREATIC-ISLETS 118
A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets 118
Antibiotic use and associated factors in a large sample of hospitalised older people 117
Cellular and molecular effects of protons: Apoptosis induction and potential implications for cancer therapy 116
A Molecular Systems BioMedicine Approach to Diabetes: Characterization, Prioritization and Network Analysis of New Candidate Genes from the Apoptotic Machinery 113
Abnormalities of Lipoprotein Levels in Liver Cirrhosis: Clinical Relevance 113
HbA1c identifies subjects with prediabetes and subclinical left ventricular diastolic dysfunction 113
Implementation of the Frailty Index in hospitalized older patients: Results from the REPOSI register 112
Analysis of S100A12 plasma levels in hyperlipidemic subjects with or without familial hypercholesterolemia 112
Atorvastatin but not pravastatin impairs mitochondrial function in human pancreatic islets and rat β-cells. Direct effect of oxidative stress 111
Serum coding and non-coding RNAs as biomarkers of NAFLD and fibrosis severity 109
Analysis of HDL-microRNA panel in heterozygous familial hypercholesterolemia subjects with LDL receptor null or defective mutation 109
A Molecular Systems BioMedicine Approach to Diabetes: Characterization, Prioritisation and Network Analysis of New Candidate Genes from the Apoptotic Machinery 108
(2012). Specifically different microRNAs profiles provide new insights on the molecular mechanisms activated by cytotoxic proinflammatory cytokines in mammalian pancreatic alpha and beta cells 108
Chronic Exposure to GLP-1 Increases GLP-1 Synthesis and Release in a Pancreatic Alpha Cell Line (α-TC1): Evidence of a Direct Effect of GLP-1 on Pancreatic Alpha Cells 107
A Molecular Systems BioMedicine Approach to Diabetes: Characterization, Prioritization and Network Analysis of New Candidate Genes from the Apoptotic Machinery 107
Hospital Care of Older Patients With COPD: Adherence to International Guidelines for Use of Inhaled Bronchodilators and Corticosteroids 107
A Molecular Systems BioMedicine Approach to Diabetes: Characterization, Prioritization and Network Analysis of New Candidate Genes from the Apoptotic Machinery 106
Alpha- and beta-cell abnormalities in haemoglobin A1c-defined prediabetes and type 2 diabetes 106
Early phase insulin secretion is increased in subjects with normal fasting glucose and metabolic syndrome: a premature feature of beta-cell dysfunction 104
Altered expression of uncoupling protein 2 in GLP-1-producing cells after chronic high glucose exposure: implications for the pathogenesis of diabetes mellitus. 104
Arterial stiffness improvement after adding on PCSK9 inhibitors or ezetimibe to high-intensity statins in patients with familial hypercholesterolemia: A Two-Lipid Center Real-World Experience 103
Action of insulin at the nuclear envelope 102
Separate impact of metabolic syndrome and altered glucose tolerance on early markers of vascular injuries. 102
High intake of dietary advanced glycation end-products is associated with increased arterial stiffness and inflammation in subjects with type 2 diabetes 102
Alterazioni lipidiche ed epatiche in soggetti con prediabete identificato in base all'emoglobina glicosilata 102
Choice and Outcomes of Rate Control versus Rhythm Control in Elderly Patients with Atrial Fibrillation: A Report from the REPOSI Study 102
Cardiovascular Risk Profile in Subjects With Prediabetes and New-Onset Type 2 Diabetes Identified by HbA1c According to American Diabetes Association Criteria 101
Altered expression of miRNAs and methylation of their promoters are correlated in neuroblastoma 100
Patterns of infections in older patients acutely admitted to medical wards: data from the REPOSI register 100
Different effects of glucose and glyburide on insulin secretion in rat pancreatic islets pre-exposed to interleukin-1β. Possible involvement of K+ and Ca2+ channels 99
A Molecular Systems BioMedicine Approach to Diabetes: Characterization, Prioritisation and Network Analysis of New Candidate Genes from the Apoptotic Machinery (AM) 99
296-3p, miR-298-5p and their downstream networks are causally involved in the higher resistance of mammalian pancreatic α cells to cytokine-induced apoptosis as compared to β cells 99
Adherence to antibiotic treatment guidelines and outcomes in the hospitalized elderly with different types of pneumonia 99
Trattamento dell’ipercolesterolemia nel soggetto con diabete mellito: Aggiornamento sugli approcci terapeutici 99
Heart failure and chronic kidney disease in a registry of internal medicine wards 99
Mortality rate and risk factors for gastrointestinal bleeding in elderly patients 99
Inflammation and ventricular-vascular coupling in hypertensive patients with metabolic syndrome 98
Smoking and diabetes: Dangerous liaisons and confusing relationships 98
Impaired Glucagon Suppression And Reduced Insulin Sensitivity In Subjects With Prediabetes Undergoing Atorvastatin Therapy 97
An increased waist-to-hip ratio is a key determinant of atherosclerotic burden in overweight subjects 96
A consensus statement for the clinical use of the renal sodium-glucose co-transporter-2 inhibitor dapagliflozin in patients with type 2 diabetes mellitus 96
Pathophysiological, Molecular and Therapeutic Issues of Nonalcoholic Fatty Liver Disease: An Overview 96
Analysis of steatosis biomarkers and inflammatory profile after adding on PCSK9 inhibitor treatment in familial hypercholesterolemia subjects with nonalcoholic fatty liver disease: a single lipid center real-world experience 96
Update on Diabetic Kidney Disease (DKD): Focus on Non-Albuminuric DKD and Cardiovascular Risk 95
L’induzione di apoptosi da parte di protoni suggerisce innovative strategie terapeutiche anticancro 95
Prevalence and Determinants of the Use of Lipid-Lowering Agents in a Population of Older Hospitalized Patients: the Findings from the REPOSI (REgistro POliterapie Società Italiana di Medicina Interna) Study 95
Circulating coding and long non-coding rnas as potential biomarkers of idiopathic pulmonary fibrosis 95
Alterazioni della funzione diastolica in pazienti con diabete tipo 2 neodiagnosticato 94
Effetti della glucotossicita' su una linea cellulare di L cellule intestinali (GLUTAg: Ruolo di UCP-2 92
L’analogo dell’insulina Lispro riduce i picchi iperglicemici post-prandiali in soggetti con diabete tipo 2 92
A molecular systems biomedicine approach to Diabetes: characterization, prioritization and network analysis of new candidate genes from the apoptotic machinery 92
Clinical and molecular biomarkers for diagnosis and staging of nafld 92
High glomerular filtration rate is associated with impaired arterial stiffness and subendocardial viability ratio in prediabetic subjects 92
Glucagon as a therapeutic approach to severe hypoglycemia: After 100 years, is it still the antidote of insulin? 91
Analysis of gingival crevicular fluid biomarkers in patients with metabolic syndrome 91
Funzione mitocondriale in isole pancreatiche di pazienti con diabete tipo 2 90
Acidi grassi polinsaturi omega 3 (PUFA): studio pilota nella terapia della NAFDL 90
Cardiovascular risk and renal injury profile in subjects with type 2 diabetes and non-albuminuric diabetic kidney disease 89
Molecular Effects of Chronic Exposure to Palmitate in Intestinal Organoids: A New Model to Study Obesity and Diabetes 88
Evaluation of high-density lipoprotein-bound long non-coding RNAs in subjects with familial hypercholesterolaemia 88
Glucose regulates both glucose transport and the glucose transporter gene expression in a hamster-derived pancreatic Beta-cell line (HIT) 88
Correlazione fra patologia tiroidea e presenza di anticorpi antitireoglobulina ed antimicrosomi tiroidei 88
VALUTAZIONE DELLA FUNZIONE BETA-CELLULARE NEGLI STADI PRECOCI DEL DIABETE MELLITO CON L'AUSILIO DI UN MODELLO MINIMO APPLICATO ALL'OGTT 88
Chronic exposure to high leucine impairs glucose-induced insulin release by lowering the ATP to ADP ratio 87
Inhibition of the high-affinity glucose transporter Glut-1 affects the sensitivity to glucose in a hamster-derived pancreatic beta cell line (HIT) 86
Early effects of high-fat diet, extra-virgin olive oil and vitamin D in a sedentary rat model of non-alcoholic fatty liver disease. 86
Anticorpi anti-GH in soggetti in trattamento con ormone della crescita: incidenza e possibile ruolo degli aggregati dell'ormone nella loro genesi 86
Role of ATP Production and Uncoupling Protein-2 in the Insulin Secretory Defect Induced by Chronic Exposure to High Glucose or Free Fatty Acids and Effects of Peroxisome Proliferator-Activated Receptor-gamma Inhibition 86
Direct and indirect effects of sars-cov-2 pandemic in subjects with familial hypercholesterolemia: A single lipid-center real-world evaluation 86
IN RAT PANCREATIC-ISLETS, IL-1-BETA INHIBITS INSULIN RELEASE BY A G-PROTEIN DEPENDENT MECHANISM 85
Low advanced glycation end product diet improves the lipid and inflammatory profiles of prediabetic subjects 85
Interleukin-1ß inhibition of insulin release in rat pancreatic islets. Possible involvment of G- Proteins in the signal transduction pathway 85
Metformin restores insulin secretion altered by chronic exposure to free fatty acids or high glucose: a direct metformin effect on pancreatic beta cells 85
Acidi grassi polinsaturi omega 3 (PUFA): studio pilota nella terapia della NAFLD 85
A molecular Systems Medicine approach to Diabetes Mellitus pinpoints the molecular bases of the higher resistance to cytokine-induced apoptosis of mammalian pancreas α cells respect to β cells 85
High glomerular filtration rate is associated with impaired arterial stiffness and subendocardial viability ratio in prediabetic subjects 85
Acute hyperbilirubinemia determines an early subclinical renal damage: Evaluation of tubular biomarkers in cholemic nephropathy 85
Direct effects of biguanides on glucose utilization in vitro 84
Porpora trombotica trombocitopenica e sindrome emolitico uremica: patologia ematologia, urgenza internistica 84
Chronic exposure to glibenclamide impairs insulin secretion in isolated rat pancreatic islets 84
Serum Albumin Is Inversely Associated With Portal Vein Thrombosis in Cirrhosis 84
Direct effects of d-chiro-inositol on insulin signaling and glucagon secretion of pancreatic alpha cells 84
Transient impairment of thyroid function in newborn from an area of endemic goiter 83
Importanza dei test alla bromocriptina e alla metergolina nelle iperprolattinemie 82
Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients 82
Totale 11.161
Categoria #
all - tutte 104.343
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 104.343


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.554 0 0 0 0 505 58 229 10 194 119 292 147
2021/20222.672 291 364 17 67 430 58 379 104 220 11 103 628
2022/20234.362 388 200 65 419 411 747 23 807 1.026 30 152 94
2023/20242.058 111 309 103 118 86 443 39 169 23 63 343 251
2024/20258.538 736 1.196 466 501 1.615 856 294 275 521 763 761 554
2025/20265.904 928 693 3.038 1.090 155 0 0 0 0 0 0 0
Totale 28.225