IRIS
RONSISVALLE, SIMONE
 Distribuzione geografica
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Continente #
NA - Nord America 4.371
EU - Europa 2.145
AS - Asia 1.559
SA - Sud America 358
AF - Africa 307
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 2
Totale 8.747
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Nazione #
US - Stati Uniti d'America 4.188
IT - Italia 808
SG - Singapore 785
CN - Cina 530
IE - Irlanda 486
UA - Ucraina 357
BR - Brasile 333
CI - Costa d'Avorio 197
CA - Canada 159
RU - Federazione Russa 124
DE - Germania 117
SN - Senegal 73
IN - India 55
GB - Regno Unito 47
SE - Svezia 47
VN - Vietnam 46
JP - Giappone 33
FI - Finlandia 30
FR - Francia 24
KR - Corea 20
NL - Olanda 17
BE - Belgio 15
CH - Svizzera 14
MX - Messico 14
UZ - Uzbekistan 14
AT - Austria 12
TR - Turchia 12
AR - Argentina 11
BD - Bangladesh 11
ZA - Sudafrica 11
PL - Polonia 10
GR - Grecia 9
CZ - Repubblica Ceca 8
DZ - Algeria 8
IQ - Iraq 8
IR - Iran 7
ES - Italia 6
LB - Libano 6
MA - Marocco 6
AU - Australia 5
CO - Colombia 4
HK - Hong Kong 4
HR - Croazia 4
JM - Giamaica 4
NG - Nigeria 4
AZ - Azerbaigian 3
BG - Bulgaria 3
EC - Ecuador 3
EG - Egitto 3
PE - Perù 3
VE - Venezuela 3
AE - Emirati Arabi Uniti 2
BH - Bahrain 2
CU - Cuba 2
DK - Danimarca 2
EU - Europa 2
IL - Israele 2
KZ - Kazakistan 2
MY - Malesia 2
SA - Arabia Saudita 2
TH - Thailandia 2
TN - Tunisia 2
AL - Albania 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
CY - Cipro 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
GE - Georgia 1
HN - Honduras 1
ID - Indonesia 1
JO - Giordania 1
KE - Kenya 1
KG - Kirghizistan 1
KW - Kuwait 1
LK - Sri Lanka 1
NO - Norvegia 1
OM - Oman 1
PA - Panama 1
PH - Filippine 1
PK - Pakistan 1
PT - Portogallo 1
PY - Paraguay 1
QA - Qatar 1
RS - Serbia 1
SL - Sierra Leone 1
Totale 8.747
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Città #
Santa Clara 709
Chandler 597
Singapore 488
Dublin 485
Jacksonville 385
Chicago 354
Boardman 210
Catania 204
Abidjan 197
Ashburn 174
Houston 146
Nanjing 130
Lawrence 126
Andover 125
Cambridge 125
Toronto 112
Civitanova Marche 92
Dakar 73
San Mateo 67
Wilmington 62
Des Moines 61
Bremen 59
Nanchang 49
Naples 44
Hefei 42
Shenyang 40
Council Bluffs 37
The Dalles 37
Dong Ket 35
Columbus 34
Ottawa 33
Saint Petersburg 33
Tokyo 33
Los Angeles 30
Tianjin 28
Munich 26
Rome 26
São Paulo 25
Changsha 24
Hebei 23
Palermo 22
Jiaxing 21
Beijing 20
Seoul 20
Falls Church 19
Grafing 16
Seattle 16
Brussels 15
Mascalucia 15
Milan 15
Kochi 14
Pune 14
Shanghai 14
Norwalk 12
Syracuse 11
Turku 11
Messina 10
Moscow 10
Belo Horizonte 9
Dearborn 9
Lappeenranta 9
Rio de Janeiro 9
Bari 8
Barlassina 8
Helsinki 8
San Francisco 8
Viagrande 8
Washington 8
Ardabil 7
East Stroudsburg 7
Jinan 7
Modica 7
New York 7
Phoenix 7
Ragusa 7
Acireale 6
Ann Arbor 6
Augusta 6
Brooklyn 6
Dallas 6
Florence 6
Goiânia 6
Johannesburg 6
Kunming 6
Liberty Lake 6
Padova 6
Warsaw 6
Amsterdam 5
Campinas 5
Den Haag 5
Guangzhou 5
Hangzhou 5
Istanbul 5
Monmouth Junction 5
Ningbo 5
Porto Alegre 5
San Antonio 5
Stockholm 5
Tappahannock 5
Abuja 4
Totale 6.124
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Nome #
In vitro evaluation of biological activities of Orobanche crenata Forssk. leaves extract 219
Involvement of sigma 2 receptor on motor disorder 169
Biological properties of Cakile maritima Scop. (Brassicaceae) extracts 133
(+)Alpha-Lipoic Acid Regulates Lipid Metabolism Gene Expression and Lipidic Profile in a Cellular Model of Fatty Acid Overload 116
Analysis of common methodological flaws in the highest cited e-cigarette epidemiology research 114
Antiproliferative activity of phenylbutyrate ester of haloperidol metabolite II [(±)-MRJF4] in prostate cancer cells 110
Antimicrobial, antioxidant, and cytotoxic activities of Juglans regia L. pellicle extract 107
Antibacterial and anti-biofilm activities of walnut pellicle extract (Juglans regia L.) against coagulase-negative staphylococci 102
Correction to: Analysis of common methodological flaws in the highest cited e-cigarette epidemiology research (Internal and Emergency Medicine, (2022), 17, 3, (887-909), 10.1007/s11739-022-02967-1) 101
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 92
Caspase-3 activation in human melanoma A375 cell line by a novel selective sigma-2 agonist 91
Pharmacological properties and biochemical mechanisms of MOR ligands might be due to different binding poses. MD Studies 91
Effects of intraplantar Nocistatin and (±)-J 113397 injections on nociceptive behavior in a rat model of inflammation 90
Competitive Formation of beta-Enaminones and 3-Amino-2(5H)-furanones from the Isoxazolidine System: A Combined Synthetic and Quantum Chemical Study 90
Critical appraisal of the European Union Scientific Committee on Health, Environmental, and Emergency Risks (SCHEER) Preliminary Opinion on electronic cigarettes 88
A novel adamantane derivative attenuates retinal ischemia-reperfusion damage in the rat retina through sigma1 receptors 85
Synthesis and in vitro evaluation of 5-arylidene-3-hydroxyalkyl-2-phenylimino-4-thiazolidinones with antidegenerative activity on human chondrocyte cultures 85
5-Arylidene-4-Thiazolidinone Derivatives Active as Antidegenerative Agents on Human Chondrocyte Cultures 84
The benzomorphan-based LP1 ligand is a suitable MOR/DOR agonist for chronic pain treatment 83
The antagonistic effect of the sigma 1 receptor ligand (+)-MR200 on persistent pain induced by inflammation. 82
The benzomorphan-based compound LP1 is a central acting MOR agonist/DOR antagonist suitable for chronic pain treatment 82
Quantum chemical and molecular dynamics studies of MUC-1 calix[4,8]arene scaffold based anti-cancer vaccine candidates 81
Benzisothiazolyliminothiazolidin-4-ones with Chondroprotective Properties: Searching for Potent and Selective Inhibitors of MMP-13 77
Heteroarylimino-4-thiazolidinones as inhibitors of cartilage degradation 77
Antinociceptive profile of LP1, a non-peptide multitarget opioid ligand. 77
Structure-Activity Relationships within a Series of σ1 and σ2 Receptor Ligands: Identification of a σ2 Receptor Agonist (BS148) with Selective Toxicity against Metastatic Melanoma 77
Anti-candidal activity of the parasitic plant orobanche crenata forssk 77
"In vitro" differences among (R) and (S) enantiomers of profens in their activities related to articular pathophysiology. 76
Neuroprotective effect of the new sigma receptor ligands cis-(+) and cis-(–)-PPCC 75
A new sigma ligand, (+/-)-PPCC, antagonizes kappa opioid receptor-mediated antinociceptive effect 75
Antioxidant and antimicrobial properties of Casteanea sativa Miller chestnut honey produced on Mount Etna (Sicily) 75
Evaluation of N-substituent structural variations in opioid receptor profile of LP1. 75
Anti-amnesic and neuroprotective actions of the sigma-1 receptor agonist (-)-MR22 in rats with selective cholinergic lesion and amyloid infusion 75
Synthesis and pharmacological evaluation of MRJF4 as new potential anticancer tool 74
Differential scanning calorimetry approach to investigate the transfer of the multitarget opioid analgesic LP1 to biomembrane model 73
Design and synthesis of trans-decahydroisoquinoline derivatives as new tramadol-like ligands 72
COMPARATIVE STUDY ON CHIRAL SEPARATION OF 3,4-DIHYDROISOQUINOLINE-2(1H)-SULFONAMIDE DERIVATIVES AS POTENT CARBONIC ANYDRASE INHIBITORS 72
From agonist to antagonist profile in LP1 analogues through the introduction of different N-substituents in benzomorphan-based ligands 72
Anti-amnesic properties of (+/-)-PPCC, a novel sigma receptor ligand, on cognitive dysfunction induced by selective cholinergic lesion in rats 72
Molecular modeling and biological studies show that some μ-opioid receptor agonists might elicit analgesia acting as MMP-9 inhibitors 72
Chemical, Antioxidant and Biological Studies of Brassica incana subsp. raimondoi (Brassicaceae) Leaf Extract 71
Synthesis and biological characterization of 3-substituted-1H-indoles as ligands of GluN2B-containing N-methyl-D-aspartate receptors. 70
EVALUATION OF THE ROLE OF INSTRUMENTAL PARAMETERS DURING THE PREPARATION OF SLN BY ULTRASONIC METHOD 70
Antimicrobial activity of Juglans regia L. pellicle extract 70
Evaluation of (–)-MR22 a novel sigma-1 receptor ligand on lesion-induced memory dysfunctions in the rat 69
2-Benzisothiazolylimino-5-benzylidene-4-thiazolidinones as protective agents against cartilage destruction 69
Novel Sigma Receptor Ligands: Synthesis and Biological Profile 68
2-Phenylimino-5-arylidene-4-thiazolidinediones. Synthesis and pharmacological evaluation on IL-1-induced alteration in certilage metabolism 68
Effects of a Selective Sigma 1 Antagonist Compound on Inflammatory Pain 68
Synthesis of 5-alkynyl isoxazolidinyl nucleosides 67
Steered molecular dynamics simulations for studying protein-ligand interaction in cyclin-dependent kinase 5 67
(+)-Mr200 derivatives: modifications on the amino moiety. In vitro and in vivo pharmacological evaluation 67
(+)-MR200 derivatives as potential new selective sigma ligands 67
Blockade of the nociceptin/orphanin FQ/NOP receptor system in the rat ventrolateral periaqueductal gray potentiates DAMGO analgesia 67
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives 67
Orobanche crenata Forssk. Extract Affects Human Breast Cancer Cell MCF-7 Survival and Viral Replication 66
Effects of Mangiferin on LPS-Induced Inflammation and SARS-CoV-2 Viral Adsorption in Human Lung Cells 66
Involvement of the Nociceptin/Orphanin FQ-NOP receptor system in the ventrolateral periaqueductal gray following mechanical allodynia in chronic pain 66
(5-Arylidene-2-thioxo-4-oxothiazolidin-3-yl)acetic acids endowed with chondroprotective and matrix metalloproteinase inhibitory activities 66
Synthesis and molecular dynamic studies on 2-(benzisothiazolyl)-N-(4-oxo-2-aryl-thiazolidinyl)-propanamides as potent inhibitors of metalloproteinases 65
ANTIALLODYNIC AND ANTIHYPERALGESIC EFFECTS OF INTRAPLANTAR NOCISTATIN AND (±)-J 113397 IN INFLAMMATORY PAIN 64
The multitarget opioid ligand LP1's effects in persistent pain and in primary cell neuronal cultures 64
Formulation of germinated brown rice fermented products functionalized by probiotics 63
Antiallodynic and antihyperalgesic effects of intraplantar nocistatin and (+/-)-J113397 in inflammatory pain 63
In-vitro evaluation of a new benzomorphan-based ligand 63
Modulation of opioid receptor profile of LP1 analogues through the introduction of different N-substituents 62
Synthesis and in vitro opioid receptor studies on benzomorphan-based compounds: LP1, a potent and long-acting antinociceptive 62
DISCOVERY OF NEW SIGMA-2 RECEPTOR AGONIST ENDOWED WITH ANTIPROLIFERATIVE ACTIVITY 61
An LP1 analogue, selective MOR agonist with a peculiar pharmacological profile, used to scrutiny the ligand binding domain 61
In-silico design and biological investigations of Diabetic Neuropathy modulators: could MOR become a focal mediator for this pathology? 61
A New LP1 analogue is used to better understand MOR ligand Binding Domain and its mechanisms of activation 60
Molecular modeling studies on mu opioid receptor of agonists and antagonists, endogenous and exogenous, ligands 60
Benzo [d]isothiazol-3-yl-benzamidines: a Class of Protective Agents on Cultures of Human Cartilage and Chondrocytes Stimulated By IL-1 beta 59
Clinical appraisal of the European Union Scientific Committee on Health, Environmental and Emerging Risks (SCHEER) Preliminary Opinion on electric cigarettes 58
In vitro evaluation of new benzomorphan-based ligands 58
Sigma receptors and tissue transglutaminase in primary rat astroglial cell cultures 58
Synthesis of MRJF4 enentiomers and evaluation of proapoptotic and cytotoxic effects in cancer cell lines 57
Pain management: new long-acting opioid ligands 57
Mangifera indica l. Leaf extract induces adiponectin and regulates adipogenesis 57
Antibacterial, Antitumor (Lung Cancer Cell H292) and Antioxidant Properties of Sicilian Prickly Pear Cactus (Opuntia Ficus-Indica) Cladode Extracts 56
Glycopeptide- and carbohydrate-based synthetic vaccines for cancer immunotherapy 56
Evaluation of N-substitution in 6,7-benzomorphan compounds 56
Pain management: new long-acting opioid ligands 56
From NMDA receptor antagonists to discovery of selective σ₂ receptor ligands 56
Design and synthesis of new bifunctional sigma-1 selective ligands with antioxidant activity. 55
Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1Areceptor agonists 55
DSC investigation of the effect ofthe new sigma ligand PPCC on DMPC lipid membrane 55
Effect of a new sigma ligand, (±)PPCC, on KOP receptor mediated analgesia 54
New benzomorphan derivatives of MPCB as MOP and KOP receptor ligands 54
Effect of hyaluronic acid and polysaccharides from Opuntiaficus indica (L.) cladodes on the metabolism of human chondrocyte cultures 53
Synthesis and pharmacological evaluation of novel series of (+)-MR-200 derivatives 53
Novel sigma receptors ligands as neuroprotective agents 53
In vitro evaluation of new benzomorphan-based ligands 53
New " Receptor Ligands with Neuroprotective Effect: Synthesis and Resolution of cis-(±)-Methyl (1R,2S/1S,2R)-2-[(4-Hydroxy-4- phenylpiperidin-1-yl)methyl]-1-(4- methylphenyl)cyclopropanecarboxylate [(±)-PPCC] 53
(+)-MR200 derivatives as potenzial new selective ligands 53
Novel potent and selective σ ligands: evaluation of their agonist and antagonist properties 52
The benzomorphan-based LP1 is a central-acting multitarget opioid ligand for chronic pain treatment. 51
LIQUID CHROMATOGRAPHIC DIRECT RESOLUTION OF 1- ARYL-1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES ON A CHIRAL STATIONARY PHASE 51
Natural flavones and flavonols: relationships among antioxidant activity, glycation and metalloproteinase inhibition 51
Different In Silico Approaches Using Heterocyclic Derivatives against the Binding between Different Lineages of SARS-CoV-2 and ACE2 50
Totale 7.266
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Categoria #
all - tutte 34.162
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 34.162
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021705 8 63 106 16 201 11 63 3 72 6 99 57
2021/2022933 110 136 3 9 139 17 136 24 93 5 34 227
2022/20231.839 141 96 37 221 155 309 14 302 434 22 78 30
2023/2024981 61 159 41 55 32 195 17 62 16 13 187 143
2024/20253.233 53 561 171 245 639 346 167 139 203 279 236 194
2025/2026161 161 0 0 0 0 0 0 0 0 0 0 0
Totale 8.974