IRIS
RONSISVALLE, SIMONE
 Distribuzione geografica
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Continente #
NA - Nord America 6.559
EU - Europa 2.249
AS - Asia 2.070
SA - Sud America 488
AF - Africa 401
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 2
Totale 11.774
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Nazione #
US - Stati Uniti d'America 6.357
SG - Singapore 879
IT - Italia 869
CN - Cina 784
IE - Irlanda 486
BR - Brasile 439
UA - Ucraina 360
CI - Costa d'Avorio 278
CA - Canada 168
RU - Federazione Russa 127
DE - Germania 118
VN - Vietnam 90
KR - Corea 73
SN - Senegal 73
IN - India 63
GB - Regno Unito 57
SE - Svezia 49
JP - Giappone 44
FI - Finlandia 33
FR - Francia 24
AR - Argentina 21
MX - Messico 20
PL - Polonia 20
BD - Bangladesh 19
HK - Hong Kong 19
NL - Olanda 19
ZA - Sudafrica 16
BE - Belgio 15
TR - Turchia 15
AT - Austria 14
CH - Svizzera 14
UZ - Uzbekistan 14
ID - Indonesia 13
MA - Marocco 10
DZ - Algeria 9
GR - Grecia 9
IQ - Iraq 9
CO - Colombia 8
CZ - Repubblica Ceca 8
EC - Ecuador 7
ES - Italia 7
IR - Iran 7
LB - Libano 6
PE - Perù 6
AU - Australia 5
AE - Emirati Arabi Uniti 4
HR - Croazia 4
JM - Giamaica 4
LT - Lituania 4
NG - Nigeria 4
TN - Tunisia 4
AZ - Azerbaigian 3
BG - Bulgaria 3
BH - Bahrain 3
EG - Egitto 3
IL - Israele 3
KZ - Kazakistan 3
MY - Malesia 3
VE - Venezuela 3
BA - Bosnia-Erzegovina 2
CU - Cuba 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
EU - Europa 2
PT - Portogallo 2
PY - Paraguay 2
SA - Arabia Saudita 2
TH - Thailandia 2
AL - Albania 1
BB - Barbados 1
BO - Bolivia 1
CR - Costa Rica 1
CY - Cipro 1
ET - Etiopia 1
GE - Georgia 1
GT - Guatemala 1
HN - Honduras 1
JO - Giordania 1
KE - Kenya 1
KG - Kirghizistan 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
MZ - Mozambico 1
NI - Nicaragua 1
NO - Norvegia 1
NP - Nepal 1
OM - Oman 1
PA - Panama 1
PH - Filippine 1
PK - Pakistan 1
QA - Qatar 1
RS - Serbia 1
SL - Sierra Leone 1
UY - Uruguay 1
Totale 11.774
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Città #
Dallas 1.951
Santa Clara 725
Chandler 597
Singapore 556
Dublin 485
Jacksonville 386
Chicago 356
Abidjan 278
Ashburn 221
Catania 214
Boardman 210
Houston 146
Hefei 142
Nanjing 130
Lawrence 126
Andover 125
Cambridge 125
Toronto 112
Beijing 99
Civitanova Marche 92
Los Angeles 80
Dakar 73
Seoul 73
San Mateo 67
Wilmington 62
Des Moines 61
Bremen 59
Nanchang 49
Naples 49
Tokyo 44
Shenyang 40
São Paulo 38
Council Bluffs 37
The Dalles 37
Dong Ket 35
Columbus 34
Palermo 34
Ottawa 33
Saint Petersburg 33
Rome 32
Tianjin 28
Munich 26
Changsha 24
Hebei 23
New York 22
Ho Chi Minh City 21
Jiaxing 21
Milan 20
Seattle 20
Falls Church 19
Mascalucia 19
Hong Kong 17
Grafing 16
Warsaw 16
Brooklyn 15
Brussels 15
Hanoi 15
Kochi 14
Pune 14
Shanghai 14
Lappeenranta 12
Norwalk 12
Bari 11
Belo Horizonte 11
Boston 11
Moscow 11
Rio de Janeiro 11
Syracuse 11
Turku 11
Messina 10
Phoenix 10
San Francisco 10
Dearborn 9
Johannesburg 9
Montreal 9
Barlassina 8
Helsinki 8
Jakarta 8
Viagrande 8
Washington 8
Ardabil 7
East Stroudsburg 7
Jinan 7
Modica 7
Porto Alegre 7
Ragusa 7
Santo André 7
Acireale 6
Amsterdam 6
Ann Arbor 6
Atlanta 6
Augusta 6
Bronte 6
Florence 6
Goiânia 6
Istanbul 6
Kunming 6
Liberty Lake 6
Padova 6
Stockholm 6
Totale 8.750
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Nome #
Expanding genotype-phenotype correlation of Kenny-Caffey syndrome type 1 391
From SARS to MERS and SARS-CoV-2: Comparative Spike Protein Remodeling and Ligand-Binding Hot-Spots Revealed by Multiscale Simulations 324
In vitro evaluation of biological activities of Orobanche crenata Forssk. leaves extract 232
(+)Alpha-Lipoic Acid Regulates Lipid Metabolism Gene Expression and Lipidic Profile in a Cellular Model of Fatty Acid Overload 211
Involvement of sigma 2 receptor on motor disorder 182
Biological properties of Cakile maritima Scop. (Brassicaceae) extracts 181
Analysis of common methodological flaws in the highest cited e-cigarette epidemiology research 171
Antiproliferative activity of phenylbutyrate ester of haloperidol metabolite II [(±)-MRJF4] in prostate cancer cells 150
Correction to: Analysis of common methodological flaws in the highest cited e-cigarette epidemiology research (Internal and Emergency Medicine, (2022), 17, 3, (887-909), 10.1007/s11739-022-02967-1) 148
Critical appraisal of the European Union Scientific Committee on Health, Environmental, and Emergency Risks (SCHEER) Preliminary Opinion on electronic cigarettes 141
Antimicrobial, antioxidant, and cytotoxic activities of Juglans regia L. pellicle extract 138
Anti-candidal activity of the parasitic plant orobanche crenata forssk 131
Antibacterial and anti-biofilm activities of walnut pellicle extract (Juglans regia L.) against coagulase-negative staphylococci 129
A novel adamantane derivative attenuates retinal ischemia-reperfusion damage in the rat retina through sigma1 receptors 127
Caspase-3 activation in human melanoma A375 cell line by a novel selective sigma-2 agonist 126
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 122
Clinical appraisal of the European Union Scientific Committee on Health, Environmental and Emerging Risks (SCHEER) Preliminary Opinion on electric cigarettes 120
5-Arylidene-4-Thiazolidinone Derivatives Active as Antidegenerative Agents on Human Chondrocyte Cultures 113
Competitive Formation of beta-Enaminones and 3-Amino-2(5H)-furanones from the Isoxazolidine System: A Combined Synthetic and Quantum Chemical Study 111
A new sigma ligand, (+/-)-PPCC, antagonizes kappa opioid receptor-mediated antinociceptive effect 111
Antinociceptive profile of LP1, a non-peptide multitarget opioid ligand. 108
Pharmacological properties and biochemical mechanisms of MOR ligands might be due to different binding poses. MD Studies 103
Anti-amnesic properties of (+/-)-PPCC, a novel sigma receptor ligand, on cognitive dysfunction induced by selective cholinergic lesion in rats 101
"In vitro" differences among (R) and (S) enantiomers of profens in their activities related to articular pathophysiology. 100
Chemical, Antioxidant and Biological Studies of Brassica incana subsp. raimondoi (Brassicaceae) Leaf Extract 98
Quantum chemical and molecular dynamics studies of MUC-1 calix[4,8]arene scaffold based anti-cancer vaccine candidates 97
Effects of intraplantar Nocistatin and (±)-J 113397 injections on nociceptive behavior in a rat model of inflammation 95
The antagonistic effect of the sigma 1 receptor ligand (+)-MR200 on persistent pain induced by inflammation. 94
Anti-amnesic and neuroprotective actions of the sigma-1 receptor agonist (-)-MR22 in rats with selective cholinergic lesion and amyloid infusion 94
Formulation of germinated brown rice fermented products functionalized by probiotics 93
(+)-Mr200 derivatives: modifications on the amino moiety. In vitro and in vivo pharmacological evaluation 93
Antioxidant and antimicrobial properties of Casteanea sativa Miller chestnut honey produced on Mount Etna (Sicily) 93
(+)-MR200 derivatives as potential new selective sigma ligands 92
Orobanche crenata Forssk. Extract Affects Human Breast Cancer Cell MCF-7 Survival and Viral Replication 91
The benzomorphan-based LP1 ligand is a suitable MOR/DOR agonist for chronic pain treatment 91
Design and synthesis of trans-decahydroisoquinoline derivatives as new tramadol-like ligands 91
Synthesis and in vitro evaluation of 5-arylidene-3-hydroxyalkyl-2-phenylimino-4-thiazolidinones with antidegenerative activity on human chondrocyte cultures 91
Antibacterial, Antitumor (Lung Cancer Cell H292) and Antioxidant Properties of Sicilian Prickly Pear Cactus (Opuntia Ficus-Indica) Cladode Extracts 90
Benzisothiazolyliminothiazolidin-4-ones with Chondroprotective Properties: Searching for Potent and Selective Inhibitors of MMP-13 90
Heteroarylimino-4-thiazolidinones as inhibitors of cartilage degradation 89
Antimicrobial activity of Juglans regia L. pellicle extract 89
2-Phenylimino-5-arylidene-4-thiazolidinediones. Synthesis and pharmacological evaluation on IL-1-induced alteration in certilage metabolism 88
COMPARATIVE STUDY ON CHIRAL SEPARATION OF 3,4-DIHYDROISOQUINOLINE-2(1H)-SULFONAMIDE DERIVATIVES AS POTENT CARBONIC ANYDRASE INHIBITORS 88
An LP1 analogue, selective MOR agonist with a peculiar pharmacological profile, used to scrutiny the ligand binding domain 88
A New LP1 analogue is used to better understand MOR ligand Binding Domain and its mechanisms of activation 88
Blockade of the nociceptin/orphanin FQ/NOP receptor system in the rat ventrolateral periaqueductal gray potentiates DAMGO analgesia 88
Neuroprotective effect of the new sigma receptor ligands cis-(+) and cis-(–)-PPCC 86
ANTIALLODYNIC AND ANTIHYPERALGESIC EFFECTS OF INTRAPLANTAR NOCISTATIN AND (±)-J 113397 IN INFLAMMATORY PAIN 86
The benzomorphan-based compound LP1 is a central acting MOR agonist/DOR antagonist suitable for chronic pain treatment 86
Evaluation of N-substituent structural variations in opioid receptor profile of LP1. 85
Effects of Mangiferin on LPS-Induced Inflammation and SARS-CoV-2 Viral Adsorption in Human Lung Cells 84
Synthesis and biological characterization of 3-substituted-1H-indoles as ligands of GluN2B-containing N-methyl-D-aspartate receptors. 83
EVALUATION OF THE ROLE OF INSTRUMENTAL PARAMETERS DURING THE PREPARATION OF SLN BY ULTRASONIC METHOD 83
(5-Arylidene-2-thioxo-4-oxothiazolidin-3-yl)acetic acids endowed with chondroprotective and matrix metalloproteinase inhibitory activities 83
(+)-MR200 derivatives as potenzial new selective ligands 83
Structure-Activity Relationships within a Series of σ1 and σ2 Receptor Ligands: Identification of a σ2 Receptor Agonist (BS148) with Selective Toxicity against Metastatic Melanoma 83
2-Benzisothiazolylimino-5-benzylidene-4-thiazolidinones as protective agents against cartilage destruction 82
Steered molecular dynamics simulations for studying protein-ligand interaction in cyclin-dependent kinase 5 80
Synthesis and pharmacological evaluation of MRJF4 as new potential anticancer tool 80
Antiallodynic and antihyperalgesic effects of intraplantar nocistatin and (+/-)-J113397 in inflammatory pain 80
Molecular modeling and biological studies show that some μ-opioid receptor agonists might elicit analgesia acting as MMP-9 inhibitors 80
Evaluation of (–)-MR22 a novel sigma-1 receptor ligand on lesion-induced memory dysfunctions in the rat 79
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives 79
Differential scanning calorimetry approach to investigate the transfer of the multitarget opioid analgesic LP1 to biomembrane model 78
Novel Sigma Receptor Ligands: Synthesis and Biological Profile 77
In-silico design and biological investigations of Diabetic Neuropathy modulators: could MOR become a focal mediator for this pathology? 77
Synthesis of 5-alkynyl isoxazolidinyl nucleosides 76
From agonist to antagonist profile in LP1 analogues through the introduction of different N-substituents in benzomorphan-based ligands 76
Identification of a novel adiponectin receptor and opioid receptor dual acting agonist as a potential treatment for diabetic neuropathy 75
Involvement of the Nociceptin/Orphanin FQ-NOP receptor system in the ventrolateral periaqueductal gray following mechanical allodynia in chronic pain 74
The multitarget opioid ligand LP1's effects in persistent pain and in primary cell neuronal cultures 74
Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1Areceptor agonists 74
Different In Silico Approaches Using Heterocyclic Derivatives against the Binding between Different Lineages of SARS-CoV-2 and ACE2 73
Effects of a Selective Sigma 1 Antagonist Compound on Inflammatory Pain 73
Evaluation of Crocin Content and In Vitro Antioxidant and Anti-Glycation Activity of Different Saffron Extracts 72
Synthesis and molecular dynamic studies on 2-(benzisothiazolyl)-N-(4-oxo-2-aryl-thiazolidinyl)-propanamides as potent inhibitors of metalloproteinases 72
In-vitro evaluation of a new benzomorphan-based ligand 72
Molecular modeling studies on mu opioid receptor of agonists and antagonists, endogenous and exogenous, ligands 72
Effect of hyaluronic acid and polysaccharides from Opuntiaficus indica (L.) cladodes on the metabolism of human chondrocyte cultures 71
Anti-malarial drugs are not created equal for sars-cov-2 treatment: A computational analysis evidence 71
Synthesis and in vitro opioid receptor studies on benzomorphan-based compounds: LP1, a potent and long-acting antinociceptive 70
New benzomorphan derivatives of MPCB as MOP and KOP receptor ligands 69
Benzo [d]isothiazol-3-yl-benzamidines: a Class of Protective Agents on Cultures of Human Cartilage and Chondrocytes Stimulated By IL-1 beta 68
Identification of a Potent and Selective 5-HT1AReceptor Agonist with in Vitro and in Vivo Antinociceptive Activity 67
Molecular Dynamic Simulations to Determine Individualized Therapy: Tetrabenazine for the GNAO1 Encephalopathy E246K Variant 66
Modulation of opioid receptor profile of LP1 analogues through the introduction of different N-substituents 66
Sigma receptors and tissue transglutaminase in primary rat astroglial cell cultures 65
Effect of a new sigma ligand, (±)PPCC, on KOP receptor mediated analgesia 65
Evaluation of N-substitution in 6,7-benzomorphan compounds 65
Pain management: new long-acting opioid ligands 65
New " Receptor Ligands with Neuroprotective Effect: Synthesis and Resolution of cis-(±)-Methyl (1R,2S/1S,2R)-2-[(4-Hydroxy-4- phenylpiperidin-1-yl)methyl]-1-(4- methylphenyl)cyclopropanecarboxylate [(±)-PPCC] 64
In vitro evaluation of new benzomorphan-based ligands 63
DISCOVERY OF NEW SIGMA-2 RECEPTOR AGONIST ENDOWED WITH ANTIPROLIFERATIVE ACTIVITY 63
Novel potent and selective σ ligands: evaluation of their agonist and antagonist properties 63
From NMDA receptor antagonists to discovery of selective σ₂ receptor ligands 63
DSC investigation of the effect ofthe new sigma ligand PPCC on DMPC lipid membrane 63
Mangifera indica l. Leaf extract induces adiponectin and regulates adipogenesis 63
In vitro evaluation of new benzomorphan-based ligands 62
Natural flavones and flavonols: relationships among antioxidant activity, glycation and metalloproteinase inhibition 62
Synthesis and pharmacological evaluation of novel series of (+)-MR-200 derivatives 60
Totale 9.733
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Categoria #
all - tutte 41.288
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 41.288
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021528 0 0 0 16 201 11 63 3 72 6 99 57
2021/2022933 110 136 3 9 139 17 136 24 93 5 34 227
2022/20231.839 141 96 37 221 155 309 14 302 434 22 78 30
2023/2024981 61 159 41 55 32 195 17 62 16 13 187 143
2024/20253.233 53 561 171 245 639 346 167 139 203 279 236 194
2025/20263.190 418 354 2.115 303 0 0 0 0 0 0 0 0
Totale 12.003