IRIS
RONSISVALLE, SIMONE
 Distribuzione geografica
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Continente #
NA - Nord America 7.848
EU - Europa 3.901
AS - Asia 3.401
SA - Sud America 647
AF - Africa 530
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 2
Totale 16.336
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Nazione #
US - Stati Uniti d'America 7.584
SG - Singapore 1.642
RU - Federazione Russa 1.357
IT - Italia 965
CN - Cina 911
BR - Brasile 524
IE - Irlanda 488
UA - Ucraina 367
VN - Vietnam 299
CI - Costa d'Avorio 278
CA - Canada 196
FR - Francia 172
DE - Germania 134
KR - Corea 128
GB - Regno Unito 104
IN - India 91
NG - Nigeria 75
SN - Senegal 73
SE - Svezia 59
JP - Giappone 55
AR - Argentina 51
PL - Polonia 47
BD - Bangladesh 44
MX - Messico 43
FI - Finlandia 38
ZA - Sudafrica 38
HK - Hong Kong 37
NL - Olanda 32
TR - Turchia 29
IQ - Iraq 27
ES - Italia 25
ID - Indonesia 23
UZ - Uzbekistan 22
EC - Ecuador 18
BE - Belgio 16
CH - Svizzera 16
AT - Austria 15
PK - Pakistan 15
CO - Colombia 14
MA - Marocco 14
GR - Grecia 12
VE - Venezuela 12
DZ - Algeria 11
CZ - Repubblica Ceca 10
EG - Egitto 10
IR - Iran 9
KE - Kenya 9
LT - Lituania 9
PE - Perù 9
TN - Tunisia 9
AU - Australia 7
BJ - Benin 7
CL - Cile 7
LB - Libano 7
CR - Costa Rica 6
IL - Israele 6
JM - Giamaica 6
MY - Malesia 6
AE - Emirati Arabi Uniti 5
HR - Croazia 5
PY - Paraguay 5
RS - Serbia 5
TH - Thailandia 5
AZ - Azerbaigian 4
BO - Bolivia 4
NP - Nepal 4
PT - Portogallo 4
AL - Albania 3
BG - Bulgaria 3
BH - Bahrain 3
BY - Bielorussia 3
DK - Danimarca 3
ET - Etiopia 3
JO - Giordania 3
KW - Kuwait 3
KZ - Kazakistan 3
MD - Moldavia 3
PH - Filippine 3
SY - Repubblica araba siriana 3
UY - Uruguay 3
BA - Bosnia-Erzegovina 2
CU - Cuba 2
CY - Cipro 2
DO - Repubblica Dominicana 2
EU - Europa 2
HU - Ungheria 2
NI - Nicaragua 2
PA - Panama 2
SA - Arabia Saudita 2
SV - El Salvador 2
TW - Taiwan 2
AM - Armenia 1
BB - Barbados 1
GE - Georgia 1
GH - Ghana 1
GT - Guatemala 1
HN - Honduras 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
Totale 16.329
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Città #
Dallas 1.959
Singapore 997
Santa Clara 742
Moscow 630
Chandler 597
Dublin 487
San Jose 442
Ashburn 407
Jacksonville 386
Chicago 360
Abidjan 278
Catania 221
Boardman 210
Houston 158
Los Angeles 153
Hefei 142
Beijing 133
Nanjing 130
Seoul 128
Lawrence 126
Andover 125
Cambridge 125
Lauterbourg 123
Toronto 115
Civitanova Marche 92
Ho Chi Minh City 92
New York 78
Dakar 73
Naples 71
San Mateo 67
Hanoi 62
Wilmington 62
Des Moines 61
Bremen 59
Council Bluffs 54
Tokyo 54
São Paulo 53
Buffalo 50
Nanchang 49
Palermo 41
Shenyang 41
Warsaw 41
Rome 39
The Dalles 37
Orem 36
Dong Ket 35
Columbus 34
Ottawa 33
Saint Petersburg 33
Lagos 32
Abuja 31
Hong Kong 30
Tianjin 30
Denver 29
Montreal 29
Brooklyn 26
Munich 26
Changsha 25
Johannesburg 25
Seattle 25
Milan 24
Hebei 23
Jiaxing 21
Falls Church 19
Mascalucia 19
Atlanta 17
Amsterdam 16
Boston 16
Brussels 16
Grafing 16
Stockholm 16
Chennai 15
Frankfurt am Main 15
London 15
Pune 15
Shanghai 15
Belo Horizonte 14
Kochi 14
Lappeenranta 14
Mexico City 14
Phoenix 14
Norwalk 12
Poplar 12
Port Harcourt 12
Rio de Janeiro 12
Bari 11
Helsinki 11
Istanbul 11
Jakarta 11
Syracuse 11
Tashkent 11
Turku 11
Da Nang 10
Haiphong 10
Manchester 10
Messina 10
Ragusa 10
San Francisco 10
Dearborn 9
Hangzhou 9
Totale 11.380
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Nome #
Expanding genotype-phenotype correlation of Kenny-Caffey syndrome type 1 443
From SARS to MERS and SARS-CoV-2: Comparative Spike Protein Remodeling and Ligand-Binding Hot-Spots Revealed by Multiscale Simulations 378
(+)Alpha-Lipoic Acid Regulates Lipid Metabolism Gene Expression and Lipidic Profile in a Cellular Model of Fatty Acid Overload 277
In vitro evaluation of biological activities of Orobanche crenata Forssk. leaves extract 265
Biological properties of Cakile maritima Scop. (Brassicaceae) extracts 240
Analysis of common methodological flaws in the highest cited e-cigarette epidemiology research 219
Correction to: Analysis of common methodological flaws in the highest cited e-cigarette epidemiology research (Internal and Emergency Medicine, (2022), 17, 3, (887-909), 10.1007/s11739-022-02967-1) 209
Involvement of sigma 2 receptor on motor disorder 206
Critical appraisal of the European Union Scientific Committee on Health, Environmental, and Emergency Risks (SCHEER) Preliminary Opinion on electronic cigarettes 204
Antimicrobial, antioxidant, and cytotoxic activities of Juglans regia L. pellicle extract 200
Antiproliferative activity of phenylbutyrate ester of haloperidol metabolite II [(±)-MRJF4] in prostate cancer cells 197
Antibacterial and anti-biofilm activities of walnut pellicle extract (Juglans regia L.) against coagulase-negative staphylococci 192
Clinical appraisal of the European Union Scientific Committee on Health, Environmental and Emerging Risks (SCHEER) Preliminary Opinion on electric cigarettes 190
A novel adamantane derivative attenuates retinal ischemia-reperfusion damage in the rat retina through sigma1 receptors 188
Anti-candidal activity of the parasitic plant orobanche crenata forssk 186
Caspase-3 activation in human melanoma A375 cell line by a novel selective sigma-2 agonist 175
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 175
A new sigma ligand, (+/-)-PPCC, antagonizes kappa opioid receptor-mediated antinociceptive effect 173
5-Arylidene-4-Thiazolidinone Derivatives Active as Antidegenerative Agents on Human Chondrocyte Cultures 171
Antibacterial, Antitumor (Lung Cancer Cell H292) and Antioxidant Properties of Sicilian Prickly Pear Cactus (Opuntia Ficus-Indica) Cladode Extracts 154
Chemical, Antioxidant and Biological Studies of Brassica incana subsp. raimondoi (Brassicaceae) Leaf Extract 150
Antinociceptive profile of LP1, a non-peptide multitarget opioid ligand. 150
Pharmacological properties and biochemical mechanisms of MOR ligands might be due to different binding poses. MD Studies 149
Orobanche crenata Forssk. Extract Affects Human Breast Cancer Cell MCF-7 Survival and Viral Replication 147
Competitive Formation of beta-Enaminones and 3-Amino-2(5H)-furanones from the Isoxazolidine System: A Combined Synthetic and Quantum Chemical Study 147
Antioxidant and antimicrobial properties of Casteanea sativa Miller chestnut honey produced on Mount Etna (Sicily) 147
(+)-MR200 derivatives as potential new selective sigma ligands 144
"In vitro" differences among (R) and (S) enantiomers of profens in their activities related to articular pathophysiology. 143
Anti-amnesic properties of (+/-)-PPCC, a novel sigma receptor ligand, on cognitive dysfunction induced by selective cholinergic lesion in rats 143
(+)-Mr200 derivatives: modifications on the amino moiety. In vitro and in vivo pharmacological evaluation 139
(+)-MR200 derivatives as potenzial new selective ligands 138
Anti-amnesic and neuroprotective actions of the sigma-1 receptor agonist (-)-MR22 in rats with selective cholinergic lesion and amyloid infusion 136
Heteroarylimino-4-thiazolidinones as inhibitors of cartilage degradation 135
2-Phenylimino-5-arylidene-4-thiazolidinediones. Synthesis and pharmacological evaluation on IL-1-induced alteration in certilage metabolism 134
A New LP1 analogue is used to better understand MOR ligand Binding Domain and its mechanisms of activation 133
Quantum chemical and molecular dynamics studies of MUC-1 calix[4,8]arene scaffold based anti-cancer vaccine candidates 131
2-Benzisothiazolylimino-5-benzylidene-4-thiazolidinones as protective agents against cartilage destruction 130
(5-Arylidene-2-thioxo-4-oxothiazolidin-3-yl)acetic acids endowed with chondroprotective and matrix metalloproteinase inhibitory activities 130
An LP1 analogue, selective MOR agonist with a peculiar pharmacological profile, used to scrutiny the ligand binding domain 130
Effects of Mangiferin on LPS-Induced Inflammation and SARS-CoV-2 Viral Adsorption in Human Lung Cells 129
The antagonistic effect of the sigma 1 receptor ligand (+)-MR200 on persistent pain induced by inflammation. 129
Antimicrobial activity of Juglans regia L. pellicle extract 129
Formulation of germinated brown rice fermented products functionalized by probiotics 128
Evaluation of Crocin Content and In Vitro Antioxidant and Anti-Glycation Activity of Different Saffron Extracts 128
Design and synthesis of trans-decahydroisoquinoline derivatives as new tramadol-like ligands 128
Blockade of the nociceptin/orphanin FQ/NOP receptor system in the rat ventrolateral periaqueductal gray potentiates DAMGO analgesia 127
Molecular modeling and biological studies show that some μ-opioid receptor agonists might elicit analgesia acting as MMP-9 inhibitors 127
Identification of a novel adiponectin receptor and opioid receptor dual acting agonist as a potential treatment for diabetic neuropathy 123
Neuroprotective effect of the new sigma receptor ligands cis-(+) and cis-(–)-PPCC 123
ANTIALLODYNIC AND ANTIHYPERALGESIC EFFECTS OF INTRAPLANTAR NOCISTATIN AND (±)-J 113397 IN INFLAMMATORY PAIN 121
Benzisothiazolyliminothiazolidin-4-ones with Chondroprotective Properties: Searching for Potent and Selective Inhibitors of MMP-13 119
COMPARATIVE STUDY ON CHIRAL SEPARATION OF 3,4-DIHYDROISOQUINOLINE-2(1H)-SULFONAMIDE DERIVATIVES AS POTENT CARBONIC ANYDRASE INHIBITORS 118
In-silico design and biological investigations of Diabetic Neuropathy modulators: could MOR become a focal mediator for this pathology? 115
Effects of intraplantar Nocistatin and (±)-J 113397 injections on nociceptive behavior in a rat model of inflammation 114
Molecular Dynamic Simulations to Determine Individualized Therapy: Tetrabenazine for the GNAO1 Encephalopathy E246K Variant 113
Synthesis and pharmacological evaluation of MRJF4 as new potential anticancer tool 113
Antiallodynic and antihyperalgesic effects of intraplantar nocistatin and (+/-)-J113397 in inflammatory pain 113
The benzomorphan-based LP1 ligand is a suitable MOR/DOR agonist for chronic pain treatment 111
Anti-malarial drugs are not created equal for sars-cov-2 treatment: A computational analysis evidence 111
Molecular modeling studies on mu opioid receptor of agonists and antagonists, endogenous and exogenous, ligands 110
Structure-Activity Relationships within a Series of σ1 and σ2 Receptor Ligands: Identification of a σ2 Receptor Agonist (BS148) with Selective Toxicity against Metastatic Melanoma 109
The benzomorphan-based compound LP1 is a central acting MOR agonist/DOR antagonist suitable for chronic pain treatment 108
Effects of a Selective Sigma 1 Antagonist Compound on Inflammatory Pain 108
In-vitro evaluation of a new benzomorphan-based ligand 107
EVALUATION OF THE ROLE OF INSTRUMENTAL PARAMETERS DURING THE PREPARATION OF SLN BY ULTRASONIC METHOD 106
Evaluation of N-substituent structural variations in opioid receptor profile of LP1. 106
Synthesis and in vitro evaluation of 5-arylidene-3-hydroxyalkyl-2-phenylimino-4-thiazolidinones with antidegenerative activity on human chondrocyte cultures 106
Novel Sigma Receptor Ligands: Synthesis and Biological Profile 103
Evaluation of N-substitution in 6,7-benzomorphan compounds 102
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives 102
Synthesis and in vitro opioid receptor studies on benzomorphan-based compounds: LP1, a potent and long-acting antinociceptive 101
Different In Silico Approaches Using Heterocyclic Derivatives against the Binding between Different Lineages of SARS-CoV-2 and ACE2 100
Evaluation of (–)-MR22 a novel sigma-1 receptor ligand on lesion-induced memory dysfunctions in the rat 100
Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1Areceptor agonists 100
Pain management: new long-acting opioid ligands 99
Synthesis and biological characterization of 3-substituted-1H-indoles as ligands of GluN2B-containing N-methyl-D-aspartate receptors. 98
The multitarget opioid ligand LP1's effects in persistent pain and in primary cell neuronal cultures 97
Differential scanning calorimetry approach to investigate the transfer of the multitarget opioid analgesic LP1 to biomembrane model 97
Steered molecular dynamics simulations for studying protein-ligand interaction in cyclin-dependent kinase 5 95
From agonist to antagonist profile in LP1 analogues through the introduction of different N-substituents in benzomorphan-based ligands 95
Synthesis and molecular dynamic studies on 2-(benzisothiazolyl)-N-(4-oxo-2-aryl-thiazolidinyl)-propanamides as potent inhibitors of metalloproteinases 95
Natural flavones and flavonols: relationships among antioxidant activity, glycation and metalloproteinase inhibition 92
Molecular Dynamics as a Precision Therapy: A Perspective on Epileptic Encephalopathies 91
Involvement of the Nociceptin/Orphanin FQ-NOP receptor system in the ventrolateral periaqueductal gray following mechanical allodynia in chronic pain 91
Effect of a new sigma ligand, (±)PPCC, on KOP receptor mediated analgesia 90
DISCOVERY OF NEW SIGMA-2 RECEPTOR AGONIST ENDOWED WITH ANTIPROLIFERATIVE ACTIVITY 89
Synthesis of MRJF4 enentiomers and evaluation of proapoptotic and cytotoxic effects in cancer cell lines 89
Identification of a Potent and Selective 5-HT1AReceptor Agonist with in Vitro and in Vivo Antinociceptive Activity 89
Synthesis of 5-alkynyl isoxazolidinyl nucleosides 88
Effect of hyaluronic acid and polysaccharides from Opuntiaficus indica (L.) cladodes on the metabolism of human chondrocyte cultures 88
In vitro evaluation of new benzomorphan-based ligands 88
New benzomorphan derivatives of MPCB as MOP and KOP receptor ligands 88
Modulation of opioid receptor profile of LP1 analogues through the introduction of different N-substituents 87
Role of iron chelation and protease inhibition of natural products on covid‐19 infection 86
Aerosol Emissions from Heated Tobacco Products: A Review Focusing on Carbonyls, Analytical Methods, and Experimental Quality 86
Cancer vaccines based on tetrameric cluster of Tn antigen glycomimetic and P3CS immunoadjuvant assembled by a rigid calix[4]arene scaffold 85
Recent Applications of In Silico Approaches for Studying Receptor Mutations Associated with Human Pathologies 83
Benzo [d]isothiazol-3-yl-benzamidines: a Class of Protective Agents on Cultures of Human Cartilage and Chondrocytes Stimulated By IL-1 beta 82
Synthesis and pharmacological evaluation of novel series of (+)-MR-200 derivatives 81
Novel potent and selective σ ligands: evaluation of their agonist and antagonist properties 81
Totale 13.415
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Categoria #
all - tutte 49.044
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 49.044
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021162 0 0 0 0 0 0 0 0 0 6 99 57
2021/2022933 110 136 3 9 139 17 136 24 93 5 34 227
2022/20231.839 141 96 37 221 155 309 14 302 434 22 78 30
2023/2024981 61 159 41 55 32 195 17 62 16 13 187 143
2024/20253.233 53 561 171 245 639 346 167 139 203 279 236 194
2025/20267.752 418 354 2.115 547 1.110 1.500 750 118 385 455 0 0
Totale 16.565