IRIS
MODICA, Maria Nunziata
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 3.955
EU - Europa 2.346
AS - Asia 1.351
SA - Sud America 230
AF - Africa 177
Continente sconosciuto - Info sul continente non disponibili 2
OC - Oceania 2
Totale 8.063
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 3.803
SG - Singapore 750
IT - Italia 565
IE - Irlanda 501
CN - Cina 483
DE - Germania 398
UA - Ucraina 375
BR - Brasile 216
FI - Finlandia 212
CA - Canada 150
CI - Costa d'Avorio 126
RU - Federazione Russa 122
SN - Senegal 40
GB - Regno Unito 34
SE - Svezia 30
IN - India 27
FR - Francia 26
UZ - Uzbekistan 21
PL - Polonia 15
VN - Vietnam 15
NL - Olanda 12
AT - Austria 10
ES - Italia 10
CH - Svizzera 8
IR - Iran 8
TR - Turchia 8
CZ - Repubblica Ceca 7
BD - Bangladesh 6
BG - Bulgaria 5
ID - Indonesia 5
JP - Giappone 5
PK - Pakistan 5
EC - Ecuador 4
IQ - Iraq 4
MA - Marocco 4
AR - Argentina 3
GR - Grecia 3
LU - Lussemburgo 3
VE - Venezuela 3
AE - Emirati Arabi Uniti 2
AU - Australia 2
EU - Europa 2
HK - Hong Kong 2
LB - Libano 2
MD - Moldavia 2
MX - Messico 2
OM - Oman 2
PY - Paraguay 2
RO - Romania 2
TN - Tunisia 2
ZA - Sudafrica 2
AO - Angola 1
BE - Belgio 1
BN - Brunei Darussalam 1
CL - Cile 1
CO - Colombia 1
DK - Danimarca 1
EG - Egitto 1
HR - Croazia 1
IL - Israele 1
JO - Giordania 1
KE - Kenya 1
KG - Kirghizistan 1
LT - Lituania 1
LV - Lettonia 1
PH - Filippine 1
PS - Palestinian Territory 1
RS - Serbia 1
Totale 8.063
Salva come PNG Salva come JPEG
Città #
Chandler 665
Dublin 501
Santa Clara 497
Singapore 429
Jacksonville 392
Munich 357
Chicago 278
Boardman 219
Ashburn 205
Helsinki 185
Catania 155
Cambridge 141
Nanjing 141
Andover 140
Lawrence 140
Abidjan 126
Toronto 123
Civitanova Marche 91
San Mateo 77
Wilmington 65
Houston 56
Des Moines 53
Nanchang 45
Shenyang 42
Dakar 40
Changsha 37
Hebei 36
Jiaxing 30
Saint Petersburg 29
São Paulo 25
Council Bluffs 24
Ottawa 24
The Dalles 24
Tianjin 21
Naples 19
Bremen 18
Redmond 18
Rome 17
Washington 17
Pune 15
Seattle 15
Augusta 13
Dong Ket 13
Jyväskylä 13
Los Angeles 13
Moscow 13
Norwalk 12
Jinan 10
Belo Horizonte 9
Falls Church 9
Leawood 9
Den Haag 8
Palermo 8
Tashkent 8
Zhengzhou 8
Ardabil 7
Beijing 7
Centro 7
Kunming 7
New York 7
Ningbo 7
Siracusa 7
Barcelona 6
Florence 6
Hefei 6
Osio Sotto 6
Rio de Janeiro 6
Fairfield 5
Jakarta 5
London 5
Milan 5
Mumbai 5
Phoenix 5
Redwood City 5
San Francisco 5
Turin 5
Turku 5
Brno 4
Changchun 4
Edinburgh 4
Ferrara di Monte Baldo 4
Fortaleza 4
Garbagnate Milanese 4
Hangzhou 4
Liberty Lake 4
Messina 4
Milazzo 4
Monmouth Junction 4
Paris 4
Reggio Calabria 4
Rescaldina 4
Salerno 4
Taizhou 4
Tokyo 4
Vicenza 4
Vienna 4
Ann Arbor 3
Civitavecchia 3
Contagem 3
Curitiba 3
Totale 5.895
Salva come PNG Salva come JPEG
Nome #
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 215
(E)-alpha-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 212
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 202
Application of PARM to constructing and comparing 5-HT1A and alfa1 receptor models 192
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 104
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 99
A focus on Heme Oxygenase-1 (HO-1) inhibitors 97
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 92
Solid lipid nanoparticles loading idebenone ester with pyroglutamic acid: In vitro antioxidant activity and in vivo topical efficacy 89
Development of Sigma Receptors Nitric Oxide Photodonor Ligands with Antiproliferative Activity 87
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 86
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 85
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 85
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 83
Synthesis and binding properties of novel selective 5-HT3 receptor ligands 82
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 82
Attività dei carotenoidi Astaxantina Crocetina e Crocina sulla inibizione dei prodotti della glicazione avanzata. 82
New synthetic approaches to bridgehead nitrogen heterocycles derived from 3-amino-2,3-dihydro-5,6-dimethyl-2-thioxo-thieno[2,3-d]pyrimidin-4(1H)-one and its salts 81
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 78
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 77
Design, sinthesis and binding properties of novel and selective 5-HT3 receptor ligands 76
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 76
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 75
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 74
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 74
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 73
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 72
5-HT7 receptor ligands: recent developments and potential therapeutic applications 72
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 71
5-HT1A receptors mapping by conformational analysis (2D NOESY/MM) and "tree way modelling" (HASL, CoMFA, PARM) 69
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 69
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 69
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 69
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 69
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 68
In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles 68
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 66
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 66
Synthesis and experimental validation of new designed heterocyclic compounds with antiproliferative activity versus breast cancer cell lines MCF-7 and MDA-MB-231 66
Antiproliferative Effect of Plant-Derived Bioactive Compounds Endowed with Antioxidant Activity on Breast Cancer Cells 65
Synthesis of new thienotriazolopyrimidine and thienopyrimidotetrazine derivatives from bifuctional intermediates 65
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 64
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 64
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 64
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 64
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 64
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 63
[[(Arylpiperazinyl)alkylthio]thieno[2,3-d]pyrimidinone derivatives as high-affinity, selective 5-HT1A receptor ligands 63
Conformational analysis and pharmacophore identification of new serotonin 5-HT4 receptor ligands made by DISCO 63
Application of Parm to constructing and comparing 5-HT1A and alfa1 receptor models 63
Building a model of interaction at the NK-2 receptors: polycondensed heterocycles containing the pyrimidoindole skeleton 63
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 62
Synthesis and pharmacological screening of 1,3,4-thiadiazino[2,3-b]quinazoline derivatives 62
Targeting the hydrophobic heme oxygenase-1 western region for the identification of novel and selective azole-based inhibitors. 62
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 61
Design and synthesis of novel potential ligands for endothelin receptors 60
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 59
Derivatives of thieno[2,3-d]pyrimidine and evaluation of their biological activity 59
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 59
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 59
(E)-alfa-[[(5-Substituted)1H-indol- 3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 59
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 59
In vitro antioxidant and anti-glycation activity of resveratrol and its novel triester with trolox 59
Arylpiperazinylalkylthio benzothiazole or benzoxazole derivatives as selective 5-HT1A serotonin receptor ligands 58
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 58
High potent and selective arylpiperazine derivatives as ligands for the 5-HT1A receptor 58
Synthesis of 2,3-dihydro-3-amino-6-phenyl-2-thioxothieno[2,3-d]pyrimidin-4(1H)-one and of potential antiinflammatory agents 2-aryl-7-phenyl-3H,9H-pyrimido[2,1-b]thieno[2',3':4,5][1,3,4]thiadiazin-9-ones 58
5-HT1A receptors mapping by conformational analysis (2D NOESY/MM) and ”three way modelling” (HASL, CoMFA, PARM) 57
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 57
Synthesis and Binding Properties of New Endothelin Receptor Ligands 56
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as novel ligands for the 5-HT7 receptor 55
Caffeic Acid Phenethyl Ester (CAPE) derivatives as novel heme oxygenase-1 inducers. 53
A new heterocyclic ring system: synthesis of pyrazolo[3',4':4,5]pyrimido-[2,1-a]phthalazine derivatives 53
Design and Synthesis of New 3-Aryl-5-oxoprolines as Potential Ligands for Human Cloned Endothelin Receptors 52
Novel arylpiperazine ligands with high affinity for alpha1-adrenergic receptor subtypes 51
New Piperidin-2,6-dione Derivatives as Ligands for the alpha1-Adrenoceptor Subtypes 51
Synthesis of 1-phenyl-6-arilsubstituted pyrazolopyrimidothiazole as antagonists at the NK-2 receptors 51
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 50
Design and Synthesis of Novel Potential Ligands for Endothelin Receptors 50
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 50
Caffeic acid phenetyl ester (CAPE) derivatives as novel heme oxygenase-1 inducers 50
Synthesis of 2,3,5,6,7,8-hexahydro-3-amino-thioxo[1]benzothieno[2,3-d]-pyrimidin-4(1H)-one and derivatives of the new heterocyclic system 7,8,9,10-tetrahydro-3H,11H-[1]benzothieno[2',3':4,5]pyrimido[2,1-b][1,3,4]-thiadiazin-11-one 50
Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for alpha1-adrenoceptor subtypes. 50
Synthesis and endothelin receptor binding affinity of a novel class of (E)-alpha-[[(5-phenylmethoxy)-1H-indol-3-yl]methylene]benzeneacetic acids 49
PARM mapping of rat and human serotonin 1A (5-HT1A) receptor 48
5-HT1A receptor binding analysis of thienopyrimidinones partial agonists: a paradigm breaking study regarding the pharmacophoric leadership of the protonated piperazine ring in GPCR ligands 48
Receptor modeling using " Multiconformer" alignment: comparison of HASL and CoMFA in the analysis of 5-HT1A thienopyrimidinone ligands 47
Evaluation of Imidazole-Based Compounds as Heme Oxygenase-1 Inhibitors 47
New Pyrimido[5,4-b]indoles and [1]Benzothieno[3,2-d]pyrimidines. High Affinity Ligands for the a 1 - Adrenoceptor Subtypes 47
New benzoxazole and benzothiazole derivatives as potential 5-HT7 receptor ligands 46
Synthesis of piperazinyl-alkylthiothieno[2,3-d]pyrimidine derivatives and serotonergic activity avaluation 46
Potential of indole skeleton containing heterocycles as antagonists at the neurokinin (NK) receptor system 46
Novel (E)-alpha-[(1H-indol-3-yl)methylene]benzeneacetic Acids as Endothelin Receptor Ligands. 45
New Synthetic approaches to fused heterocycloquinazolines 45
New compounds controlling NO overproduction 45
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as Heme Oxygenase-1 inhibitors and their antitumor properties 44
Ligandi per le sottoclassi del recettore alfa1-adrenergico. Nuovi derivati benzotieno[3,2-d]pirimidin-(1H,3H)2,4-dionici-8-sostituiti 44
Design and synthesis of new high-affinity, selective 5-HT3 and 5-HT4 receptors ligands 44
Synthesis of new [1,3,4]thiadiazolo[3,2-a]thieno[2,3-d]pyrimidinone derivatives with antiinflammatory activity 44
Sintesi di nuovi derivati 4-fenilpiperidin-2,6-dionici come potenziali liganti per le sottoclassi del recettore alfa1-adrenergico 43
Totale 6.883
Salva come PNG Salva come JPEG
Categoria #
all - tutte 29.797
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 29.797
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020111 0 0 0 0 0 0 0 0 0 0 76 35
2020/2021695 6 68 82 13 218 11 72 4 49 9 132 31
2021/20221.043 130 145 21 10 150 16 149 42 92 7 49 232
2022/20231.801 166 101 39 196 190 314 1 295 392 23 64 20
2023/2024792 39 107 38 33 68 218 5 50 2 20 132 80
2024/20252.883 24 478 165 173 539 345 317 223 323 220 76 0
Totale 8.361