IRIS
MODICA, Maria Nunziata
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 4.182
EU - Europa 2.413
AS - Asia 1.586
SA - Sud America 322
AF - Africa 189
Continente sconosciuto - Info sul continente non disponibili 2
OC - Oceania 2
Totale 8.696
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 4.007
SG - Singapore 835
IT - Italia 577
CN - Cina 561
IE - Irlanda 501
DE - Germania 404
UA - Ucraina 378
BR - Brasile 299
FI - Finlandia 225
CA - Canada 162
CI - Costa d'Avorio 126
RU - Federazione Russa 124
GB - Regno Unito 49
IN - India 42
SN - Senegal 40
SE - Svezia 31
FR - Francia 30
UZ - Uzbekistan 22
PL - Polonia 21
VN - Vietnam 21
BD - Bangladesh 18
ES - Italia 14
TR - Turchia 14
IQ - Iraq 12
NL - Olanda 12
KR - Corea 11
AT - Austria 10
ZA - Sudafrica 9
CH - Svizzera 8
CZ - Repubblica Ceca 8
IR - Iran 8
JP - Giappone 8
MX - Messico 8
MA - Marocco 6
PK - Pakistan 6
VE - Venezuela 6
AR - Argentina 5
BG - Bulgaria 5
EC - Ecuador 5
ID - Indonesia 5
AE - Emirati Arabi Uniti 4
PY - Paraguay 4
GR - Grecia 3
JO - Giordania 3
LU - Lussemburgo 3
TN - Tunisia 3
AU - Australia 2
AZ - Azerbaigian 2
EU - Europa 2
HK - Hong Kong 2
HN - Honduras 2
IL - Israele 2
KE - Kenya 2
LB - Libano 2
MD - Moldavia 2
OM - Oman 2
RO - Romania 2
TT - Trinidad e Tobago 2
AO - Angola 1
BE - Belgio 1
BN - Brunei Darussalam 1
CL - Cile 1
CO - Colombia 1
DK - Danimarca 1
EG - Egitto 1
GY - Guiana 1
HR - Croazia 1
KG - Kirghizistan 1
LT - Lituania 1
LV - Lettonia 1
NG - Nigeria 1
NP - Nepal 1
PH - Filippine 1
PS - Palestinian Territory 1
RS - Serbia 1
SA - Arabia Saudita 1
SV - El Salvador 1
Totale 8.696
Salva come PNG Salva come JPEG
Città #
Chandler 665
Singapore 514
Santa Clara 503
Dublin 501
Jacksonville 392
Munich 362
Chicago 282
Ashburn 227
Boardman 219
Helsinki 185
Catania 156
Cambridge 141
Nanjing 141
Andover 140
Lawrence 140
Abidjan 126
Toronto 123
Civitanova Marche 91
San Mateo 77
Beijing 72
Wilmington 65
Houston 56
Des Moines 53
Nanchang 45
Shenyang 42
Dakar 40
Changsha 37
Hebei 36
São Paulo 33
Jiaxing 30
Saint Petersburg 29
Council Bluffs 28
Los Angeles 28
Rome 28
Columbus 24
Ottawa 24
The Dalles 24
Tianjin 21
Hefei 19
Naples 19
Bremen 18
Redmond 18
Turku 18
Seattle 17
Washington 17
Brooklyn 16
Pune 15
Augusta 13
Belo Horizonte 13
Dong Ket 13
Jyväskylä 13
Moscow 13
New York 13
Norwalk 12
Seoul 11
Jinan 10
Mumbai 10
Boston 9
Dhaka 9
Falls Church 9
Leawood 9
London 9
San Francisco 9
Tashkent 9
Den Haag 8
Palermo 8
Phoenix 8
Zhengzhou 8
Ardabil 7
Centro 7
Johannesburg 7
Kunming 7
Ningbo 7
Rio de Janeiro 7
Siracusa 7
Tokyo 7
Warsaw 7
Baghdad 6
Barcelona 6
Florence 6
Osio Sotto 6
Atlanta 5
Fairfield 5
Fortaleza 5
Jakarta 5
Milan 5
Montreal 5
Redwood City 5
Turin 5
Ankara 4
Brno 4
Canoas 4
Changchun 4
Curitiba 4
Dallas 4
Edinburgh 4
Ferrara di Monte Baldo 4
Garbagnate Milanese 4
Goiânia 4
Hangzhou 4
Totale 6.244
Salva come PNG Salva come JPEG
Nome #
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 221
(E)-alpha-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 218
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 213
Application of PARM to constructing and comparing 5-HT1A and alfa1 receptor models 196
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 115
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 108
A focus on Heme Oxygenase-1 (HO-1) inhibitors 102
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 102
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 95
Solid lipid nanoparticles loading idebenone ester with pyroglutamic acid: In vitro antioxidant activity and in vivo topical efficacy 95
Development of Sigma Receptors Nitric Oxide Photodonor Ligands with Antiproliferative Activity 93
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 92
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 89
Attività dei carotenoidi Astaxantina Crocetina e Crocina sulla inibizione dei prodotti della glicazione avanzata. 89
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 88
Synthesis and binding properties of novel selective 5-HT3 receptor ligands 87
New synthetic approaches to bridgehead nitrogen heterocycles derived from 3-amino-2,3-dihydro-5,6-dimethyl-2-thioxo-thieno[2,3-d]pyrimidin-4(1H)-one and its salts 86
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 85
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 83
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 81
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 80
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 80
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 79
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 79
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 78
Design, sinthesis and binding properties of novel and selective 5-HT3 receptor ligands 77
5-HT7 receptor ligands: recent developments and potential therapeutic applications 77
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 77
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 76
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 76
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 76
5-HT1A receptors mapping by conformational analysis (2D NOESY/MM) and "tree way modelling" (HASL, CoMFA, PARM) 75
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 75
In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles 75
Antiproliferative Effect of Plant-Derived Bioactive Compounds Endowed with Antioxidant Activity on Breast Cancer Cells 73
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 73
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 72
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 72
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 71
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 71
Synthesis of new thienotriazolopyrimidine and thienopyrimidotetrazine derivatives from bifuctional intermediates 70
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 70
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 70
Synthesis and experimental validation of new designed heterocyclic compounds with antiproliferative activity versus breast cancer cell lines MCF-7 and MDA-MB-231 70
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 70
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 69
[[(Arylpiperazinyl)alkylthio]thieno[2,3-d]pyrimidinone derivatives as high-affinity, selective 5-HT1A receptor ligands 69
Application of Parm to constructing and comparing 5-HT1A and alfa1 receptor models 69
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 68
Targeting the hydrophobic heme oxygenase-1 western region for the identification of novel and selective azole-based inhibitors. 68
Building a model of interaction at the NK-2 receptors: polycondensed heterocycles containing the pyrimidoindole skeleton 67
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 67
Synthesis and pharmacological screening of 1,3,4-thiadiazino[2,3-b]quinazoline derivatives 67
Conformational analysis and pharmacophore identification of new serotonin 5-HT4 receptor ligands made by DISCO 65
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 65
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 65
(E)-alfa-[[(5-Substituted)1H-indol- 3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 65
Derivatives of thieno[2,3-d]pyrimidine and evaluation of their biological activity 64
Synthesis and Binding Properties of New Endothelin Receptor Ligands 64
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 64
In vitro antioxidant and anti-glycation activity of resveratrol and its novel triester with trolox 64
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 63
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 63
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 63
5-HT1A receptors mapping by conformational analysis (2D NOESY/MM) and ”three way modelling” (HASL, CoMFA, PARM) 63
Design and synthesis of novel potential ligands for endothelin receptors 62
High potent and selective arylpiperazine derivatives as ligands for the 5-HT1A receptor 62
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 62
Synthesis of 2,3-dihydro-3-amino-6-phenyl-2-thioxothieno[2,3-d]pyrimidin-4(1H)-one and of potential antiinflammatory agents 2-aryl-7-phenyl-3H,9H-pyrimido[2,1-b]thieno[2',3':4,5][1,3,4]thiadiazin-9-ones 61
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 59
Arylpiperazinylalkylthio benzothiazole or benzoxazole derivatives as selective 5-HT1A serotonin receptor ligands 59
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as novel ligands for the 5-HT7 receptor 59
A new heterocyclic ring system: synthesis of pyrazolo[3',4':4,5]pyrimido-[2,1-a]phthalazine derivatives 56
Novel arylpiperazine ligands with high affinity for alpha1-adrenergic receptor subtypes 55
New Piperidin-2,6-dione Derivatives as Ligands for the alpha1-Adrenoceptor Subtypes 55
Design and Synthesis of New 3-Aryl-5-oxoprolines as Potential Ligands for Human Cloned Endothelin Receptors 54
Caffeic Acid Phenethyl Ester (CAPE) derivatives as novel heme oxygenase-1 inducers. 54
Design and Synthesis of Novel Potential Ligands for Endothelin Receptors 53
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 53
Synthesis of 2,3,5,6,7,8-hexahydro-3-amino-thioxo[1]benzothieno[2,3-d]-pyrimidin-4(1H)-one and derivatives of the new heterocyclic system 7,8,9,10-tetrahydro-3H,11H-[1]benzothieno[2',3':4,5]pyrimido[2,1-b][1,3,4]-thiadiazin-11-one 53
Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for alpha1-adrenoceptor subtypes. 53
New benzoxazole and benzothiazole derivatives as potential 5-HT7 receptor ligands 52
Synthesis of 1-phenyl-6-arilsubstituted pyrazolopyrimidothiazole as antagonists at the NK-2 receptors 52
5-HT1A receptor binding analysis of thienopyrimidinones partial agonists: a paradigm breaking study regarding the pharmacophoric leadership of the protonated piperazine ring in GPCR ligands 52
Caffeic acid phenetyl ester (CAPE) derivatives as novel heme oxygenase-1 inducers 52
Receptor modeling using " Multiconformer" alignment: comparison of HASL and CoMFA in the analysis of 5-HT1A thienopyrimidinone ligands 51
Synthesis and endothelin receptor binding affinity of a novel class of (E)-alpha-[[(5-phenylmethoxy)-1H-indol-3-yl]methylene]benzeneacetic acids 50
New Pyrimido[5,4-b]indoles and [1]Benzothieno[3,2-d]pyrimidines. High Affinity Ligands for the a 1 - Adrenoceptor Subtypes 50
Potential of indole skeleton containing heterocycles as antagonists at the neurokinin (NK) receptor system 50
Novel (E)-alpha-[(1H-indol-3-yl)methylene]benzeneacetic Acids as Endothelin Receptor Ligands. 49
PARM mapping of rat and human serotonin 1A (5-HT1A) receptor 49
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as Heme Oxygenase-1 inhibitors and their antitumor properties 48
Design and synthesis of new high-affinity, selective 5-HT3 and 5-HT4 receptors ligands 48
Novel inhibitors of nitric oxide synthase with antioxidant properties 48
Targeting Heme Oxygenase-1 to Overcome Imatinib Resistance in Chronic Myeloid Leukemia 48
New Synthetic approaches to fused heterocycloquinazolines 47
Synthesis of piperazinyl-alkylthiothieno[2,3-d]pyrimidine derivatives and serotonergic activity avaluation 47
Evaluation of Imidazole-Based Compounds as Heme Oxygenase-1 Inhibitors 47
Strategies to improve resveratrol systemic and topical bioavailability: An update 47
New compounds controlling NO overproduction 46
Totale 7.355
Salva come PNG Salva come JPEG
Categoria #
all - tutte 32.499
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 32.499
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021689 0 68 82 13 218 11 72 4 49 9 132 31
2021/20221.043 130 145 21 10 150 16 149 42 92 7 49 232
2022/20231.801 166 101 39 196 190 314 1 295 392 23 64 20
2023/2024792 39 107 38 33 68 218 5 50 2 20 132 80
2024/20253.187 24 478 165 173 539 345 317 223 323 220 192 188
2025/2026329 329 0 0 0 0 0 0 0 0 0 0 0
Totale 8.994