IRIS
MODICA, Maria Nunziata
 Distribuzione geografica
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Continente #
NA - Nord America 6.459
EU - Europa 3.606
AS - Asia 3.017
SA - Sud America 559
AF - Africa 359
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 3
Totale 14.006
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Nazione #
US - Stati Uniti d'America 6.208
SG - Singapore 1.591
RU - Federazione Russa 984
CN - Cina 787
IT - Italia 612
IE - Irlanda 505
BR - Brasile 471
DE - Germania 417
UA - Ucraina 387
FI - Finlandia 234
VN - Vietnam 214
CA - Canada 198
CI - Costa d'Avorio 195
FR - Francia 188
KR - Corea 92
GB - Regno Unito 83
IN - India 79
NG - Nigeria 56
SE - Svezia 45
BD - Bangladesh 40
SN - Senegal 40
PL - Polonia 37
HK - Hong Kong 32
AR - Argentina 31
UZ - Uzbekistan 29
ES - Italia 27
MX - Messico 26
IQ - Iraq 25
JP - Giappone 25
ZA - Sudafrica 24
TR - Turchia 21
NL - Olanda 19
EC - Ecuador 16
KE - Kenya 16
AT - Austria 14
PK - Pakistan 13
VE - Venezuela 13
ID - Indonesia 12
MA - Marocco 11
IR - Iran 9
CH - Svizzera 8
CO - Colombia 8
CZ - Repubblica Ceca 8
JM - Giamaica 8
JO - Giordania 8
PY - Paraguay 8
GR - Grecia 7
AE - Emirati Arabi Uniti 6
EG - Egitto 6
BG - Bulgaria 5
CL - Cile 5
PH - Filippine 5
TN - Tunisia 5
IL - Israele 4
LB - Libano 4
LT - Lituania 4
MY - Malesia 4
TT - Trinidad e Tobago 4
AL - Albania 3
AU - Australia 3
AZ - Azerbaigian 3
BO - Bolivia 3
HN - Honduras 3
LU - Lussemburgo 3
LV - Lettonia 3
NI - Nicaragua 3
RO - Romania 3
SA - Arabia Saudita 3
UY - Uruguay 3
DK - Danimarca 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
EU - Europa 2
GT - Guatemala 2
KW - Kuwait 2
MD - Moldavia 2
NP - Nepal 2
OM - Oman 2
AO - Angola 1
BE - Belgio 1
BJ - Benin 1
BN - Brunei Darussalam 1
BT - Bhutan 1
CR - Costa Rica 1
CU - Cuba 1
ET - Etiopia 1
GY - Guiana 1
HR - Croazia 1
HU - Ungheria 1
KG - Kirghizistan 1
PA - Panama 1
PS - Palestinian Territory 1
PT - Portogallo 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
SV - El Salvador 1
TG - Togo 1
TH - Thailandia 1
VG - Isole Vergini Britanniche 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 14.006
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Città #
Dallas 1.013
Singapore 915
Chandler 665
Santa Clara 545
Dublin 505
San Jose 445
Ashburn 429
Moscow 404
Jacksonville 393
Munich 362
Chicago 289
Boardman 219
Abidjan 195
Helsinki 191
Catania 158
Nanjing 142
Cambridge 141
Andover 140
Lawrence 140
Toronto 132
Lauterbourg 131
Beijing 124
Los Angeles 98
Seoul 92
Civitanova Marche 91
San Mateo 77
Ho Chi Minh City 73
Wilmington 66
Houston 65
São Paulo 58
Hefei 54
Des Moines 53
New York 50
Council Bluffs 45
Nanchang 45
Hanoi 43
Shenyang 42
Dakar 40
Changsha 39
Hebei 36
Rome 32
Jiaxing 30
Saint Petersburg 29
Buffalo 28
Hong Kong 28
Orem 28
Lagos 25
Ottawa 25
Abuja 24
Brooklyn 24
Columbus 24
The Dalles 24
Tokyo 23
Tianjin 22
Montreal 21
Phoenix 21
Belo Horizonte 20
Naples 20
Warsaw 20
Atlanta 19
Bremen 18
Johannesburg 18
Redmond 18
Seattle 18
Turku 18
Washington 17
Mumbai 16
Pune 16
London 15
Tashkent 15
Augusta 13
Da Nang 13
Dong Ket 13
Jyväskylä 13
Rio de Janeiro 13
Baghdad 12
Manchester 12
Norwalk 12
Dhaka 11
Palermo 11
San Francisco 11
Boston 10
Jinan 10
Redondo Beach 10
Stockholm 10
Chennai 9
Denver 9
Falls Church 9
Jakarta 9
Leawood 9
Mexico City 9
Curitiba 8
Den Haag 8
Istanbul 8
Quito 8
Zhengzhou 8
Amman 7
Amsterdam 7
Ardabil 7
Centro 7
Totale 9.697
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Nome #
(E)-alpha-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 316
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 299
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 295
Application of PARM to constructing and comparing 5-HT1A and alfa1 receptor models 237
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 191
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 186
(E)-alfa-[[(5-Substituted)1H-indol- 3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 169
A focus on Heme Oxygenase-1 (HO-1) inhibitors 164
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 159
Attività dei carotenoidi Astaxantina Crocetina e Crocina sulla inibizione dei prodotti della glicazione avanzata. 158
Antiproliferative Effect of Plant-Derived Bioactive Compounds Endowed with Antioxidant Activity on Breast Cancer Cells 156
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 156
Development of Sigma Receptors Nitric Oxide Photodonor Ligands with Antiproliferative Activity 153
Solid lipid nanoparticles loading idebenone ester with pyroglutamic acid: In vitro antioxidant activity and in vivo topical efficacy 150
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 149
5-HT7 receptor ligands: recent developments and potential therapeutic applications 148
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 148
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 146
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 146
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 143
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 135
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 135
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 134
5-HT1A receptors mapping by conformational analysis (2D NOESY/MM) and "tree way modelling" (HASL, CoMFA, PARM) 134
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 134
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 133
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 132
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 132
In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles 128
New synthetic approaches to bridgehead nitrogen heterocycles derived from 3-amino-2,3-dihydro-5,6-dimethyl-2-thioxo-thieno[2,3-d]pyrimidin-4(1H)-one and its salts 127
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 126
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 125
Synthesis and binding properties of novel selective 5-HT3 receptor ligands 124
In vitro antioxidant and anti-glycation activity of resveratrol and its novel triester with trolox 121
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 120
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 120
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 118
High potent and selective arylpiperazine derivatives as ligands for the 5-HT1A receptor 117
Targeting the hydrophobic heme oxygenase-1 western region for the identification of novel and selective azole-based inhibitors. 117
[[(Arylpiperazinyl)alkylthio]thieno[2,3-d]pyrimidinone derivatives as high-affinity, selective 5-HT1A receptor ligands 116
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 115
Application of Parm to constructing and comparing 5-HT1A and alfa1 receptor models 115
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 114
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 112
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 111
5-HT1A receptor binding analysis of thienopyrimidinones partial agonists: a paradigm breaking study regarding the pharmacophoric leadership of the protonated piperazine ring in GPCR ligands 111
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 111
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 110
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 108
5-HT1A receptors mapping by conformational analysis (2D NOESY/MM) and ”three way modelling” (HASL, CoMFA, PARM) 108
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 107
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 105
Synthesis and pharmacological screening of 1,3,4-thiadiazino[2,3-b]quinazoline derivatives 105
Synthesis of new thienotriazolopyrimidine and thienopyrimidotetrazine derivatives from bifuctional intermediates 103
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 103
Building a model of interaction at the NK-2 receptors: polycondensed heterocycles containing the pyrimidoindole skeleton 103
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 102
Synthesis and Binding Properties of New Endothelin Receptor Ligands 102
A new heterocyclic ring system: synthesis of pyrazolo[3',4':4,5]pyrimido-[2,1-a]phthalazine derivatives 102
Synthesis and experimental validation of new designed heterocyclic compounds with antiproliferative activity versus breast cancer cell lines MCF-7 and MDA-MB-231 102
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 101
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinolinecarboxylic acid derivatives 98
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 98
Design and synthesis of novel potential ligands for endothelin receptors 96
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 95
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 95
Derivatives of thieno[2,3-d]pyrimidine and evaluation of their biological activity 94
Design, sinthesis and binding properties of novel and selective 5-HT3 receptor ligands 91
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 91
Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for alpha1-adrenoceptor subtypes. 91
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as novel ligands for the 5-HT7 receptor 89
Conformational analysis and pharmacophore identification of new serotonin 5-HT4 receptor ligands made by DISCO 89
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 87
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 86
Design and Synthesis of Novel Potential Ligands for Endothelin Receptors 83
Synthesis of 2,3-dihydro-3-amino-6-phenyl-2-thioxothieno[2,3-d]pyrimidin-4(1H)-one and of potential antiinflammatory agents 2-aryl-7-phenyl-3H,9H-pyrimido[2,1-b]thieno[2',3':4,5][1,3,4]thiadiazin-9-ones 83
Arylpiperazinylalkylthio benzothiazole or benzoxazole derivatives as selective 5-HT1A serotonin receptor ligands 80
Evaluation of Imidazole-Based Compounds as Heme Oxygenase-1 Inhibitors 80
Design and Synthesis of New 3-Aryl-5-oxoprolines as Potential Ligands for Human Cloned Endothelin Receptors 79
Novel arylpiperazine ligands with high affinity for alpha1-adrenergic receptor subtypes 79
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 79
Targeting Heme Oxygenase-1 to Overcome Imatinib Resistance in Chronic Myeloid Leukemia 79
New compounds controlling NO overproduction 78
New benzoxazole and benzothiazole derivatives as potential 5-HT7 receptor ligands 78
Synthesis and endothelin receptor binding affinity of a novel class of (E)-alpha-[[(5-phenylmethoxy)-1H-indol-3-yl]methylene]benzeneacetic acids 78
Caffeic Acid Phenethyl Ester (CAPE) derivatives as novel heme oxygenase-1 inducers. 78
New Pyrimido[5,4-b]indoles and [1]Benzothieno[3,2-d]pyrimidines. High Affinity Ligands for the a 1 - Adrenoceptor Subtypes 78
Caffeic acid phenetyl ester (CAPE) derivatives as novel heme oxygenase-1 inducers 76
Strategies to improve resveratrol systemic and topical bioavailability: An update 76
Synthesis of 2,3,5,6,7,8-hexahydro-3-amino-thioxo[1]benzothieno[2,3-d]-pyrimidin-4(1H)-one and derivatives of the new heterocyclic system 7,8,9,10-tetrahydro-3H,11H-[1]benzothieno[2',3':4,5]pyrimido[2,1-b][1,3,4]-thiadiazin-11-one 75
Potential of indole skeleton containing heterocycles as antagonists at the neurokinin (NK) receptor system 75
Receptor modeling using " Multiconformer" alignment: comparison of HASL and CoMFA in the analysis of 5-HT1A thienopyrimidinone ligands 74
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as Heme Oxygenase-1 inhibitors and their antitumor properties 73
New Piperidin-2,6-dione Derivatives as Ligands for the alpha1-Adrenoceptor Subtypes 73
Design and synthesis of new high-affinity, selective 5-HT3 and 5-HT4 receptors ligands 73
Novel inhibitors of nitric oxide synthase with antioxidant properties 73
Novel (E)-alpha-[(1H-indol-3-yl)methylene]benzeneacetic Acids as Endothelin Receptor Ligands. 72
New Synthetic approaches to fused heterocycloquinazolines 72
Novel selective ligands for the serotonergic 5-HT7 receptor: tricyclic derivatives Bearing the pyrimido-4(3H)-one ring 72
Synthesis of 1-phenyl-6-arilsubstituted pyrazolopyrimidothiazole as antagonists at the NK-2 receptors 71
Totale 11.634
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Categoria #
all - tutte 46.344
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.344
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.043 130 145 21 10 150 16 149 42 92 7 49 232
2022/20231.801 166 101 39 196 190 314 1 295 392 23 64 20
2023/2024792 39 107 38 33 68 218 5 50 2 20 132 80
2024/20253.187 24 478 165 173 539 345 317 223 323 220 192 188
2025/20265.606 329 184 1.114 311 908 1.098 653 106 292 318 178 115
2026/202736 36 0 0 0 0 0 0 0 0 0 0 0
Totale 14.307