IRIS
GUCCIONE, Salvatore
 Distribuzione geografica
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Continente #
NA - Nord America 5.952
AS - Asia 3.144
EU - Europa 2.959
SA - Sud America 517
AF - Africa 258
Continente sconosciuto - Info sul continente non disponibili 233
OC - Oceania 4
Totale 13.067
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Nazione #
US - Stati Uniti d'America 5.692
SG - Singapore 1.660
RU - Federazione Russa 906
CN - Cina 822
IE - Irlanda 509
UA - Ucraina 469
IT - Italia 426
BR - Brasile 404
VN - Vietnam 226
CA - Canada 197
FR - Francia 161
DE - Germania 134
KR - Corea 86
SE - Svezia 84
CI - Costa d'Avorio 75
NG - Nigeria 68
FI - Finlandia 66
GB - Regno Unito 66
IN - India 58
SN - Senegal 49
BD - Bangladesh 48
AR - Argentina 45
MX - Messico 35
IQ - Iraq 32
HK - Hong Kong 31
TR - Turchia 22
NL - Olanda 21
UZ - Uzbekistan 21
PL - Polonia 20
EC - Ecuador 19
JP - Giappone 19
CH - Svizzera 18
ID - Indonesia 18
ZA - Sudafrica 18
PK - Pakistan 15
VE - Venezuela 14
ES - Italia 13
IR - Iran 13
AT - Austria 12
BE - Belgio 12
CO - Colombia 12
EU - Europa 10
MA - Marocco 10
IL - Israele 8
AE - Emirati Arabi Uniti 7
CL - Cile 7
EG - Egitto 7
HN - Honduras 7
KE - Kenya 7
PY - Paraguay 7
BJ - Benin 6
CZ - Repubblica Ceca 6
JO - Giordania 6
NP - Nepal 6
GR - Grecia 5
KZ - Kazakistan 5
LB - Libano 5
LT - Lituania 5
PH - Filippine 5
SA - Arabia Saudita 5
AU - Australia 4
BG - Bulgaria 4
DZ - Algeria 4
ET - Etiopia 4
KG - Kirghizistan 4
MD - Moldavia 4
MY - Malesia 4
PE - Perù 4
TN - Tunisia 4
AL - Albania 3
AZ - Azerbaigian 3
BY - Bielorussia 3
CR - Costa Rica 3
HU - Ungheria 3
JM - Giamaica 3
UY - Uruguay 3
AO - Angola 2
BA - Bosnia-Erzegovina 2
BN - Brunei Darussalam 2
BO - Bolivia 2
DO - Repubblica Dominicana 2
GT - Guatemala 2
KW - Kuwait 2
NI - Nicaragua 2
OM - Oman 2
PS - Palestinian Territory 2
QA - Qatar 2
TH - Thailandia 2
AG - Antigua e Barbuda 1
AI - Anguilla 1
BB - Barbados 1
BH - Bahrain 1
BM - Bermuda 1
CU - Cuba 1
DK - Danimarca 1
GD - Grenada 1
HR - Croazia 1
LU - Lussemburgo 1
LV - Lettonia 1
LY - Libia 1
Totale 12.833
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Città #
Singapore 930
Dallas 894
Santa Clara 670
Chandler 514
Dublin 508
Jacksonville 494
San Jose 402
Moscow 341
Ashburn 264
Chicago 264
Boardman 225
Nanjing 156
Lawrence 144
Cambridge 143
Andover 141
Toronto 137
Lauterbourg 131
Civitanova Marche 105
Hefei 102
Catania 95
Beijing 93
Los Angeles 88
Munich 87
Seoul 85
Ho Chi Minh City 84
Houston 79
San Mateo 79
Abidjan 75
Des Moines 69
Helsinki 59
Shenyang 55
Wilmington 52
Hanoi 51
Dakar 49
Nanchang 49
Hebei 42
Saint Petersburg 40
São Paulo 36
Council Bluffs 34
Abuja 33
Lagos 30
Tianjin 30
New York 29
Buffalo 27
Hong Kong 27
Ottawa 27
Jiaxing 25
Changsha 21
Orem 19
Brooklyn 18
Montreal 18
Atlanta 17
Tokyo 17
Naples 16
Denver 15
Rio de Janeiro 15
Bremen 14
Da Nang 14
Johannesburg 14
Rome 14
Baghdad 13
Seattle 13
Amsterdam 12
Brussels 12
Phoenix 12
Pune 12
Warsaw 12
Augusta 11
Bari 11
Belo Horizonte 11
Columbus 11
Haiphong 11
Mexico City 10
Norwalk 10
Redondo Beach 10
The Dalles 10
Ardabil 9
Curitiba 9
Mumbai 9
Poplar 9
Stockholm 9
Washington 9
Barlassina 8
Leawood 8
London 8
Tashkent 8
Ankara 7
Boston 7
Brasília 7
Campinas 7
Charlotte 7
Chennai 7
Frankfurt am Main 7
Kunming 7
Mascalucia 7
Quito 7
San Francisco 7
Zhengzhou 7
Ann Arbor 6
Asunción 6
Totale 8.669
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Nome #
Application of PARM to constructing and comparing 5-HT1A and alfa1 receptor models 237
Pharmacological properties and biochemical mechanisms of MOR ligands might be due to different binding poses. MD Studies 156
Lipophilic conjugates of methotrexate with short-chain alkylamino acids as DHFR inhibitors. Synthesis, biological evaluation, and molecular modeling 154
Correlating in Vitro Target-Oriented Screening and Docking: Inhibition of Matrix Metalloproteinases Activities by Flavonoids 148
A 3D QSAR study of Monoamino Oxidase B inhibitors, using the chemical function based pharmacophore generation approach 145
5-HT1A receptors mapping by conformational analysis (2D NOESY/MM) and "tree way modelling" (HASL, CoMFA, PARM) 135
Drug delivery of synthetic antisense “Bioconjugates” for anticancer therapy DNA. 135
4 Methyl-2-[N-(3,4-methylenedioxy-benzylidene)hydrazino]thiazole and its reduction product, 4-methyl-2-[N-(3,4-methylenedioxybenzylidene)-hydrazono]-4,5-dihydrothiazole 133
Quantum chemical and molecular dynamics studies of MUC-1 calix[4,8]arene scaffold based anti-cancer vaccine candidates 133
Molecular modeling and biological studies show that some μ-opioid receptor agonists might elicit analgesia acting as MMP-9 inhibitors 131
Identification of a novel adiponectin receptor and opioid receptor dual acting agonist as a potential treatment for diabetic neuropathy 126
A new procedure for the synthesis of 4H-pyrazolo[1,5-c][1,3,5]thiadiazine-4-thiones 124
An efficient procedure for the synthesis of Pyrazolo[3,4-d] [1,3] Thiazin-4-ones 120
Drug Delivery of Synthetic Antisense-DNA “bioconjugates” for Anticancer Therapy 120
16. Towards a complete picture of chiral discrimination processes by C9 carbamate derivatives of dihydroquinine: interaction mechanisms of diastereoisomeric 9-O-[(S)- or (R)-1-(1-naphthyl)ethylcarbamate]dihydroquinine and the two enantiomers of N-(3,5-dinitrobenzoyl)alanine methyl ester 120
In-silico design and biological investigations of Diabetic Neuropathy modulators: could MOR become a focal mediator for this pathology? 120
Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity 119
Alkylation of non-electron rich nitrogen heterocycles by alkyl orthoformates: quantum chemistry calculations 117
Application of Parm to constructing and comparing 5-HT1A and alfa1 receptor models 115
5HT1a Receptor Binding Affinities of a Series of Serotonin Transporter (SERT) Inhibitors and Related Thermodynamic Insights 113
3D-QSAR Using ”Multiconformer” Alignment: The Use of HASL in the Analysis of 5-HT1A Thienopyrimidinone Ligands 113
Molecular modeling studies on mu opioid receptor of agonists and antagonists, endogenous and exogenous, ligands 113
Sulfonilamidothiopyrimidone and thiopyrimidone derivatives as selective COX-2 inhibitors: Synthesis, biological evaluation, and docking studies 111
5-HT1A receptor binding analysis of thienopyrimidinones partial agonists: a paradigm breaking study regarding the pharmacophoric leadership of the protonated piperazine ring in GPCR ligands 111
5-HT1A receptors mapping by conformational analysis (2D NOESY/MM) and ”three way modelling” (HASL, CoMFA, PARM) 111
Binding of imidazline ligands to the active site of purified MAO A 109
In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase 109
An Alternative Method for 3D-QSAR and the Alignment of Molecular Structures: BiS (Biological Substrate Search) 108
TCP-FA4: A derivative of tranylcypromine showing improved blood-brain permeability 107
A field-based disparity analysis of new 1,2,5- oxadiazole derivatives endowed with antiproliferative activity 106
Imidazole Derivatives as Heme Oxygenase-1 Inhibitors 105
Exploring the biological activity of a library of 1,2,5-oxadiazole derivatives endowed with antiproliferative activity 105
Building a model of interaction at the NK-2 receptors: polycondensed heterocycles containing the pyrimidoindole skeleton 104
Potential of Aryl-urea-Benzofuranylthiazoles hybrids as multitasking agents in Alzheimer’s disease 103
Synthesis and pharmacological evaluation of benzothieno and [1]pyridothieno [2,3-d]triazole derivatives as antagonists at NK-1 receptors 103
Spectroscopic Investigation and Molecular Modeling on Porphyrin/PAMAM Supramolecular Adduct 102
Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids. I. Synthesis and biological evaluation of lipophilic conjugates of tranylcypromine 102
Pyrimido[5,4-b] Indole derivatives. 1. A new class of potent and selective alpha-1 adrenoceptor ligands 102
Molecular modelling of a novel class of N5-methanesulfonamide dihydrothienopyrimidinoners as potential dual COX-2 inhibitor/ 102
ML10302 102
Interaction of natural flavonoid eriocitrin with beta-cyclodextrin and hydroxypropyl-beta-cyclodextrin: an NMR and molecular dynamics investigation 100
Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids II. Experimental and computational evidence using biomembrane models 99
Application of PARM to constructing and comparing 5-HT1A and alpha1 receptor models 99
Parameters for irreversible inactivation of monoamine oxidase 99
Sensory Analysis on Red Wines: Discrimination by Adaptive Fuzzy Partition (AFP) 97
Homology-based modeling of rhodopsin-like family members in the inactive state: structural analysis and deduction of tips for modeling and optimization. 97
Preparation, characterisation and photosensitivity studies of solid dispersions of diflunisal and Eudragit RS100 (R) and RL100 (R) 97
DRUG DELIVERY OF SYNTHETIC ANTISENSE-DNA "BIOCONJUGATES" FOR ANTICANCER THERAPY 97
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases 95
A method for determination of form and sizes of pocket in "receptor-ligand" complexes 95
Stereoretentive Chlorination of Cyclic Alcohols Catalyzed by Titanium (IV) Tetrachloride: Evidence for a Front Side Attack Mechanism. 94
The cell cycle molecules behind neurodegeneration in Alzheimer's disease: perspectives for drug development 93
Heterocyclic systems containing the pyrimido-2,4-dione ring as selective ligands for the alpha1-adrenoceptors 93
Combining molecular modeling with experimental methodologies: mechanism of membrane permeation and accumulation of ofloxacin 93
How to choose the suitable template for homology modelling of GPCRs: 5-HT7 receptor as a test case 90
Building a model of interaction at the NK-2 receptors: Polycondensed heterocycles containing the pyrimidoindole skeleton 90
Potential of alkyl orthoformates as alkylating agents of non-electron rich nitrogen heterocycles 89
Conformational analysis and pharmacophore identification of new serotonin 5-HT4 receptor ligands made by DISCO 89
Synthesis and pharmacological activity of 6H-thiazolo[3’,2’:1,2]-5-oxopyrimido[5,4-b] Indole derivatives, a new heterocyclic ring system 89
Structural data: the basis for molecular modelling 88
Heme Oxygenase 1 and Heme Oxygenase 2 As Druggable Targets: Docking and Two Hybrid System To Identifying and Characterizing Protein-Proten Interactions. 88
Recent Applications of In Silico Approaches for Studying Receptor Mutations Associated with Human Pathologies 87
Molecular modelling and site-directed mutagenesis reveal essential residues for 5-HT7 receptor binding 87
Peptidomimetics in Silico 87
Theoretical calculations of the catalytic triad in short chain alcohol dehydrogenases/reductases 86
Potential immunoregulatory role of heme oxygenase-1 in human milk: a combined biochemical and molecular modeling approach 86
Thiazole derivatives as inhibitors of purified bovine liver mitochondrial monoamine oxidase-B: structure-activity relationships and theoretical study 86
Carbohydrate-Ligand Complex Binding: EMPIRICAL FREE ENERGY MODELING 84
Synthesis and pharmacological evaluation of pyrazolopyrimidobenzoxazole and pyrazolopyrimidobenzothiazole derivatives 83
Interactions of imidazoline ligands with the active site of purified monoamine oxidase A 82
COMBINING NMR AND MOLECULAR MODELLING IN A DRUG DELIVERY CONTEXT: investigation of the multi-mode inclusion of a new NPY-5 antagonist bromobenzenesulfonamide into beta-cyclodextrin 82
Hydrophobic molecular similarity from MST fractional contributions to the octanol/water partition coefficient 81
MULTIGEN: A NEW PARADIGM FOR “MULTICONFORMATIONAL” ALIGNMENT OF MOLECULAR STRUCTURES IN 3D-QSAR STUDIES 81
Evaluation of Imidazole-Based Compounds as Heme Oxygenase-1 Inhibitors 81
Crystallographic, NMR and ab initio calculation studies of tautomerism among substituted thiazol-2-yl-hydrazines 81
Multi-conformational method of analysis of biological activity of molecular structures 81
Design, synthesis and docking study of novel coumarin ligands as potential selective acetylcholinesterase inhibitors 80
Identification of an impurity in the synthesis of pharmacologically active pyrazolotriazolopyrimidines by a combined spectrometric approach 80
Identification of essential residues for binding and activation in the human 5-HT7(a) serotonin receptor by molecular modeling and site-directed mutagenesis 80
Docking simulation of complex between 2,5-xilidine and Rigidoporus lignosus laccase 80
Substrate and inhibitor specificity of class 1 and class 2 histone deacetylases 79
Molecular modelling of a novel class of N5-methanesulfonamide dihydrothienopyrimidinoners as as potential dual COX-2 inhibitor/nitric oxide anti-releasing agents 79
DESIGN AND SYNTHESIS OF MULTIPLE LIGANS: NEW ARYLAMINES AND THEIR BINDING AFFINITY TOWARD 5-HT TRANSPORTER (SERT) AND 5-HT7- RECEPTORS 79
Potential of Pyrazolooxadiazinone Derivatives as Serine Protease Inhibitors 79
Combined NMR-crystallographic and modelling investigation of the inclusion of molsidomine into alpha-, beta - and gamma -cyclodextrins 79
Sequential application of ligand and structure based modeling approaches to index chemicals for their hH4R antagonism 77
Potential of indole skeleton containing heterocycles as antagonists at the neurokinin (NK) receptor system 76
How does binding of imidazole-based inhibitors to heme oxygenase-1 influence their conformation? Insights combining crystal structures and molecular modelling 75
Study on new neurokinin antagonists: polycondensed heterocycles containing the indole skeleton 75
STUDY OF STRUCTURAL AND DYNAMIC BEHAVIOUR OF IBUPROFEN AND ITS COMPLEXES WITH EUDRAGIT® RL100 BY NERANS OF SOLID STATE 75
Modelling-filtered drug repurposing and first-in-protein SPR validation of histone deacetylase 4 inhibitors for Ataxia-telangiectasia 74
Synthesis and pharmacological properties of pyrazolotriazolopyrimidine derivatives 74
Comparing Log P Calculations by the Ghose-Crippen and Villar Methods 74
Receptor modeling using " Multiconformer" alignment: comparison of HASL and CoMFA in the analysis of 5-HT1A thienopyrimidinone ligands 74
Emerging antifungal azoles and effects on Magnaporthe grisea 74
New heterocyclic ring systems. Synthesis and pharmacological activity of 6H-1,3,4-thiadiazolo [3’,2’: 1,2]-5-oxopyrimido[5,4-b]indole derivatives and of 1-phenyl-6H-1,2,4-Triazolo [1’,5’: 1,2]-5-oxopyrimido [5,4-b]Indole 74
Synthesis of 1-phenyl-6-arilsubstituted pyrazolopyrimidothiazole as antagonists at the NK-2 receptors 72
Synthesis and COMFA study of new heterocyclic compounds as potential AcylCoA: cholesterol O-acyltransferase inhibitors 72
Rescuing Abandoned Molecules as Nav1.7 and PCSK9 Inhibitors 72
PARM mapping of rat and human serotonin 1A (5-HT1A) receptor 70
Totale 9.878
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Categoria #
all - tutte 44.509
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 44.509
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022983 132 146 0 15 153 5 142 25 100 0 36 229
2022/20231.570 148 55 34 119 175 287 0 300 372 5 53 22
2023/2024508 39 67 22 38 25 81 3 12 2 15 133 71
2024/20252.677 14 464 133 155 492 349 104 128 241 264 138 195
2025/20265.287 286 189 977 377 877 987 709 108 238 311 129 99
2026/202795 95 0 0 0 0 0 0 0 0 0 0 0
Totale 13.067