IRIS
GUCCIONE, Salvatore
 Distribuzione geografica
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Continente #
NA - Nord America 3.908
EU - Europa 1.881
AS - Asia 1.438
SA - Sud America 209
AF - Africa 107
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 3
Totale 7.556
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Nazione #
US - Stati Uniti d'America 3.730
SG - Singapore 805
CN - Cina 524
IE - Irlanda 515
UA - Ucraina 468
IT - Italia 352
BR - Brasile 187
CA - Canada 169
RU - Federazione Russa 144
DE - Germania 125
SE - Svezia 78
FI - Finlandia 64
SN - Senegal 48
CI - Costa d'Avorio 47
GB - Regno Unito 30
IN - India 25
CH - Svizzera 19
FR - Francia 16
UZ - Uzbekistan 16
AT - Austria 12
BE - Belgio 12
IR - Iran 11
NL - Olanda 11
EU - Europa 10
PL - Polonia 9
AR - Argentina 8
VN - Vietnam 8
IL - Israele 7
BD - Bangladesh 6
IQ - Iraq 6
GR - Grecia 5
HK - Hong Kong 5
TR - Turchia 5
CZ - Repubblica Ceca 4
EC - Ecuador 4
PY - Paraguay 4
ZA - Sudafrica 4
AU - Australia 3
BG - Bulgaria 3
EG - Egitto 3
ES - Italia 3
HN - Honduras 3
JP - Giappone 3
LB - Libano 3
MA - Marocco 3
MD - Moldavia 3
MX - Messico 3
PK - Pakistan 3
BN - Brunei Darussalam 2
CO - Colombia 2
SA - Arabia Saudita 2
VE - Venezuela 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BM - Bermuda 1
CL - Cile 1
CR - Costa Rica 1
DK - Danimarca 1
HR - Croazia 1
HU - Ungheria 1
JO - Giordania 1
KG - Kirghizistan 1
KZ - Kazakistan 1
LT - Lituania 1
LU - Lussemburgo 1
MN - Mongolia 1
NP - Nepal 1
OM - Oman 1
RO - Romania 1
TN - Tunisia 1
TT - Trinidad e Tobago 1
UY - Uruguay 1
Totale 7.556
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Città #
Santa Clara 653
Chandler 521
Dublin 515
Jacksonville 502
Singapore 480
Chicago 265
Boardman 231
Nanjing 158
Lawrence 146
Cambridge 145
Andover 142
Toronto 135
Civitanova Marche 106
Catania 90
Munich 87
San Mateo 80
Ashburn 76
Des Moines 69
Houston 69
Helsinki 58
Shenyang 55
Wilmington 53
Nanchang 49
Dakar 48
Abidjan 47
Hebei 43
Saint Petersburg 40
Hefei 36
Tianjin 30
Los Angeles 27
Ottawa 27
Jiaxing 25
Changsha 22
Beijing 14
Bremen 14
Council Bluffs 14
Naples 14
Brussels 12
The Dalles 12
Augusta 11
Bari 11
Moscow 11
Pune 11
Seattle 11
São Paulo 11
Norwalk 10
Ardabil 9
Barlassina 8
Leawood 8
Washington 8
Belo Horizonte 7
Zhengzhou 7
Ann Arbor 6
Dong Ket 6
Frankfurt Am Main 6
Jinan 6
Kunming 6
Liberty Lake 6
Ludwigshafen 6
Rome 6
Atlanta 5
Den Haag 5
Guangzhou 5
Hangzhou 5
Modica 5
Ningbo 5
Phoenix 5
Rio de Janeiro 5
Syracuse 5
Agrigento 4
Brooklyn 4
Dallas 4
Hong Kong 4
Mumbai 4
New York 4
Ragusa 4
Amsterdam 3
Asunción 3
Baghdad 3
Brasília 3
Campinas 3
Changchun 3
Curitiba 3
Edinburgh 3
Fuzhou 3
Lesignano de' Bagni 3
Londrina 3
Melbourne 3
San Gregorio di Catania 3
Santo André 3
Sorocaba 3
Tashkent 3
Tokyo 3
Acireale 2
Ankara 2
Araruama 2
Araucária 2
Bandar Seri Begawan 2
Basra 2
Betim 2
Totale 5.419
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Nome #
Application of PARM to constructing and comparing 5-HT1A and alfa1 receptor models 193
Lipophilic conjugates of methotrexate with short-chain alkylamino acids as DHFR inhibitors. Synthesis, biological evaluation, and molecular modeling 117
Pharmacological properties and biochemical mechanisms of MOR ligands might be due to different binding poses. MD Studies 91
Quantum chemical and molecular dynamics studies of MUC-1 calix[4,8]arene scaffold based anti-cancer vaccine candidates 80
4 Methyl-2-[N-(3,4-methylenedioxy-benzylidene)hydrazino]thiazole and its reduction product, 4-methyl-2-[N-(3,4-methylenedioxybenzylidene)-hydrazono]-4,5-dihydrothiazole 78
A new procedure for the synthesis of 4H-pyrazolo[1,5-c][1,3,5]thiadiazine-4-thiones 76
Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity 75
Correlating in Vitro Target-Oriented Screening and Docking: Inhibition of Matrix Metalloproteinases Activities by Flavonoids 74
Drug delivery of synthetic antisense “Bioconjugates” for anticancer therapy DNA. 74
Alkylation of non-electron rich nitrogen heterocycles by alkyl orthoformates: quantum chemistry calculations 72
A 3D QSAR study of Monoamino Oxidase B inhibitors, using the chemical function based pharmacophore generation approach 72
In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase 72
Molecular modeling and biological studies show that some μ-opioid receptor agonists might elicit analgesia acting as MMP-9 inhibitors 72
Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids II. Experimental and computational evidence using biomembrane models 71
An efficient procedure for the synthesis of Pyrazolo[3,4-d] [1,3] Thiazin-4-ones 70
Preparation, characterisation and photosensitivity studies of solid dispersions of diflunisal and Eudragit RS100 (R) and RL100 (R) 70
5-HT1A receptors mapping by conformational analysis (2D NOESY/MM) and "tree way modelling" (HASL, CoMFA, PARM) 70
16. Towards a complete picture of chiral discrimination processes by C9 carbamate derivatives of dihydroquinine: interaction mechanisms of diastereoisomeric 9-O-[(S)- or (R)-1-(1-naphthyl)ethylcarbamate]dihydroquinine and the two enantiomers of N-(3,5-dinitrobenzoyl)alanine methyl ester 70
Spectroscopic Investigation and Molecular Modeling on Porphyrin/PAMAM Supramolecular Adduct 69
The cell cycle molecules behind neurodegeneration in Alzheimer's disease: perspectives for drug development 69
Potential of Aryl-urea-Benzofuranylthiazoles hybrids as multitasking agents in Alzheimer’s disease 69
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases 69
5HT1a Receptor Binding Affinities of a Series of Serotonin Transporter (SERT) Inhibitors and Related Thermodynamic Insights 69
TCP-FA4: A derivative of tranylcypromine showing improved blood-brain permeability 68
DRUG DELIVERY OF SYNTHETIC ANTISENSE-DNA "BIOCONJUGATES" FOR ANTICANCER THERAPY 68
How to choose the suitable template for homology modelling of GPCRs: 5-HT7 receptor as a test case 67
3D-QSAR Using ”Multiconformer” Alignment: The Use of HASL in the Analysis of 5-HT1A Thienopyrimidinone Ligands 67
Stereoretentive Chlorination of Cyclic Alcohols Catalyzed by Titanium (IV) Tetrachloride: Evidence for a Front Side Attack Mechanism. 66
Sensory Analysis on Red Wines: Discrimination by Adaptive Fuzzy Partition (AFP) 65
Homology-based modeling of rhodopsin-like family members in the inactive state: structural analysis and deduction of tips for modeling and optimization. 65
Structural data: the basis for molecular modelling 65
Application of Parm to constructing and comparing 5-HT1A and alfa1 receptor models 65
Building a model of interaction at the NK-2 receptors: polycondensed heterocycles containing the pyrimidoindole skeleton 65
Conformational analysis and pharmacophore identification of new serotonin 5-HT4 receptor ligands made by DISCO 64
Drug Delivery of Synthetic Antisense-DNA “bioconjugates” for Anticancer Therapy 63
Combining molecular modeling with experimental methodologies: mechanism of membrane permeation and accumulation of ofloxacin 61
In-silico design and biological investigations of Diabetic Neuropathy modulators: could MOR become a focal mediator for this pathology? 61
Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids. I. Synthesis and biological evaluation of lipophilic conjugates of tranylcypromine 60
Theoretical calculations of the catalytic triad in short chain alcohol dehydrogenases/reductases 60
An Alternative Method for 3D-QSAR and the Alignment of Molecular Structures: BiS (Biological Substrate Search) 60
Potential of alkyl orthoformates as alkylating agents of non-electron rich nitrogen heterocycles 59
Heme Oxygenase 1 and Heme Oxygenase 2 As Druggable Targets: Docking and Two Hybrid System To Identifying and Characterizing Protein-Proten Interactions. 59
Molecular modelling of a novel class of N5-methanesulfonamide dihydrothienopyrimidinoners as potential dual COX-2 inhibitor/ 59
Molecular modelling and site-directed mutagenesis reveal essential residues for 5-HT7 receptor binding 59
5-HT1A receptors mapping by conformational analysis (2D NOESY/MM) and ”three way modelling” (HASL, CoMFA, PARM) 59
Molecular modeling studies on mu opioid receptor of agonists and antagonists, endogenous and exogenous, ligands 59
Heterocyclic systems containing the pyrimido-2,4-dione ring as selective ligands for the alpha1-adrenoceptors 58
Binding of imidazline ligands to the active site of purified MAO A 58
Imidazole Derivatives as Heme Oxygenase-1 Inhibitors 58
Sulfonilamidothiopyrimidone and thiopyrimidone derivatives as selective COX-2 inhibitors: Synthesis, biological evaluation, and docking studies 58
Potential immunoregulatory role of heme oxygenase-1 in human milk: a combined biochemical and molecular modeling approach 58
Multi-conformational method of analysis of biological activity of molecular structures 58
Synthesis and pharmacological activity of 6H-thiazolo[3’,2’:1,2]-5-oxopyrimido[5,4-b] Indole derivatives, a new heterocyclic ring system 58
Design, synthesis and docking study of novel coumarin ligands as potential selective acetylcholinesterase inhibitors 57
Pyrazolothiazolopyrimidine derivatives as novel class of anti-inflammatory or antinociceptive agents: synthesis, structural characterization and pharmacological evaluation 56
Pyrimido[5,4-b] Indole derivatives. 1. A new class of potent and selective alpha-1 adrenoceptor ligands 56
DESIGN AND SYNTHESIS OF MULTIPLE LIGANS: NEW ARYLAMINES AND THEIR BINDING AFFINITY TOWARD 5-HT TRANSPORTER (SERT) AND 5-HT7- RECEPTORS 55
Carbohydrate-Ligand Complex Binding: EMPIRICAL FREE ENERGY MODELING 55
ML10302 55
Crystallographic, NMR and ab initio calculation studies of tautomerism among substituted thiazol-2-yl-hydrazines 55
Application of PARM to constructing and comparing 5-HT1A and alpha1 receptor models 54
Synthesis and pharmacological evaluation of benzothieno and [1]pyridothieno [2,3-d]triazole derivatives as antagonists at NK-1 receptors 54
Synthesis and pharmacological evaluation of pyrazolopyrimidobenzoxazole and pyrazolopyrimidobenzothiazole derivatives 54
Study on new neurokinin antagonists: polycondensed heterocycles containing the indole skeleton 54
A field-based disparity analysis of new 1,2,5- oxadiazole derivatives endowed with antiproliferative activity 54
Sequential application of ligand and structure based modeling approaches to index chemicals for their hH4R antagonism 54
Hydrophobic molecular similarity from MST fractional contributions to the octanol/water partition coefficient 52
Synthesis and pharmacological properties of pyrazolotriazolopyrimidine derivatives 52
Identification of essential residues for binding and activation in the human 5-HT7(a) serotonin receptor by molecular modeling and site-directed mutagenesis 52
MULTIGEN: A NEW PARADIGM FOR “MULTICONFORMATIONAL” ALIGNMENT OF MOLECULAR STRUCTURES IN 3D-QSAR STUDIES 52
Synthesis of 1-phenyl-6-arilsubstituted pyrazolopyrimidothiazole as antagonists at the NK-2 receptors 52
Combined NMR-crystallographic and modelling investigation of the inclusion of molsidomine into alpha-, beta - and gamma -cyclodextrins 52
A method for determination of form and sizes of pocket in "receptor-ligand" complexes 52
Thiazole derivatives as inhibitors of purified bovine liver mitochondrial monoamine oxidase-B: structure-activity relationships and theoretical study 51
Exploring the biological activity of a library of 1,2,5-oxadiazole derivatives endowed with antiproliferative activity 51
Parameters for irreversible inactivation of monoamine oxidase 51
Interactions of imidazoline ligands with the active site of purified monoamine oxidase A 50
Substrate and inhibitor specificity of class 1 and class 2 histone deacetylases 50
Building a model of interaction at the NK-2 receptors: Polycondensed heterocycles containing the pyrimidoindole skeleton 50
Interaction of natural flavonoid eriocitrin with beta-cyclodextrin and hydroxypropyl-beta-cyclodextrin: an NMR and molecular dynamics investigation 50
Receptor modeling using " Multiconformer" alignment: comparison of HASL and CoMFA in the analysis of 5-HT1A thienopyrimidinone ligands 49
PARM mapping of rat and human serotonin 1A (5-HT1A) receptor 49
5-HT1A receptor binding analysis of thienopyrimidinones partial agonists: a paradigm breaking study regarding the pharmacophoric leadership of the protonated piperazine ring in GPCR ligands 49
Docking simulation of complex between 2,5-xilidine and Rigidoporus lignosus laccase 49
Emerging antifungal azoles and effects on Magnaporthe grisea 49
Peptidomimetics in Silico 49
Identification of an impurity in the synthesis of pharmacologically active pyrazolotriazolopyrimidines by a combined spectrometric approach 48
COMBINING NMR AND MOLECULAR MODELLING IN A DRUG DELIVERY CONTEXT: investigation of the multi-mode inclusion of a new NPY-5 antagonist bromobenzenesulfonamide into beta-cyclodextrin 48
Potential of indole skeleton containing heterocycles as antagonists at the neurokinin (NK) receptor system 48
Computational Comparison of Imidazoline Association with the I2 Binding Site in Human Monoamine Oxidases 47
Comparing Log P Calculations by the Ghose-Crippen and Villar Methods 47
Evaluation of Imidazole-Based Compounds as Heme Oxygenase-1 Inhibitors 47
Potential of Pyrazolooxadiazinone Derivatives as Serine Protease Inhibitors 47
New heterocyclic ring systems. Synthesis and pharmacological activity of 6H-1,3,4-thiadiazolo [3’,2’: 1,2]-5-oxopyrimido[5,4-b]indole derivatives and of 1-phenyl-6H-1,2,4-Triazolo [1’,5’: 1,2]-5-oxopyrimido [5,4-b]Indole 47
Study of structural and dynamic behaviour of ibuprofen and its complexes with Eudragit® RL100 by means of solid state NMR 47
Molecular modelling of a novel class of N5-methanesulfonamide dihydrothienopyrimidinoners as as potential dual COX-2 inhibitor/nitric oxide anti-releasing agents 46
Heme oxygenase-1 and Heme oxygenase-2 as druggable targets: Docking and two-hybrid system to identify and characterize protein-protein interaction 46
Synthesis and COMFA study of new heterocyclic compounds as potential AcylCoA: cholesterol O-acyltransferase inhibitors 46
STUDY OF STRUCTURAL AND DYNAMIC BEHAVIOUR OF IBUPROFEN AND ITS COMPLEXES WITH EUDRAGIT® RL100 BY NERANS OF SOLID STATE 46
Molecular Modelling of endothelin ETA and ETB 45
Totale 6.071
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Categoria #
all - tutte 28.869
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.869
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202030 0 0 0 0 0 0 0 0 0 0 0 30
2020/2021846 3 73 131 22 243 26 80 3 73 4 148 40
2021/2022996 134 148 0 15 156 5 143 25 101 0 37 232
2022/20231.593 150 55 34 120 179 291 0 305 377 6 54 22
2023/2024517 39 68 23 39 25 81 4 12 2 16 136 72
2024/20252.697 14 472 134 157 501 351 104 132 244 270 143 175
Totale 7.774