IRIS
GUCCIONE, Salvatore
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 5.208
AS - Asia 2.385
EU - Europa 1.999
SA - Sud America 439
AF - Africa 159
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 3
Totale 10.203
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 4.997
SG - Singapore 1.270
CN - Cina 770
IE - Irlanda 516
UA - Ucraina 472
BR - Brasile 363
IT - Italia 356
RU - Federazione Russa 206
CA - Canada 185
DE - Germania 125
VN - Vietnam 100
SE - Svezia 83
CI - Costa d'Avorio 75
FI - Finlandia 65
GB - Regno Unito 51
SN - Senegal 48
KR - Corea 44
IN - India 42
AR - Argentina 33
BD - Bangladesh 20
CH - Svizzera 19
NL - Olanda 19
UZ - Uzbekistan 19
FR - Francia 16
MX - Messico 16
PL - Polonia 16
EC - Ecuador 15
ID - Indonesia 15
TR - Turchia 15
IQ - Iraq 13
IR - Iran 13
ZA - Sudafrica 13
AT - Austria 12
BE - Belgio 12
HK - Hong Kong 12
JP - Giappone 12
EU - Europa 10
IL - Israele 8
PY - Paraguay 8
VE - Venezuela 8
BJ - Benin 7
CO - Colombia 5
ES - Italia 5
GR - Grecia 5
MA - Marocco 5
CZ - Repubblica Ceca 4
LB - Libano 4
PK - Pakistan 4
AE - Emirati Arabi Uniti 3
AU - Australia 3
BG - Bulgaria 3
CL - Cile 3
EG - Egitto 3
HN - Honduras 3
JO - Giordania 3
KE - Kenya 3
MD - Moldavia 3
NP - Nepal 3
PE - Perù 3
SA - Arabia Saudita 3
BA - Bosnia-Erzegovina 2
BN - Brunei Darussalam 2
DO - Repubblica Dominicana 2
KZ - Kazakistan 2
LT - Lituania 2
TN - Tunisia 2
AL - Albania 1
AO - Angola 1
AZ - Azerbaigian 1
BM - Bermuda 1
BY - Bielorussia 1
CR - Costa Rica 1
CU - Cuba 1
DK - Danimarca 1
ET - Etiopia 1
GT - Guatemala 1
HR - Croazia 1
HU - Ungheria 1
KG - Kirghizistan 1
KW - Kuwait 1
LU - Lussemburgo 1
MN - Mongolia 1
MR - Mauritania 1
MY - Malesia 1
OM - Oman 1
PH - Filippine 1
RO - Romania 1
TH - Thailandia 1
TT - Trinidad e Tobago 1
UY - Uruguay 1
Totale 10.203
Salva come PNG Salva come JPEG
Città #
Dallas 895
Santa Clara 661
Singapore 616
Chandler 521
Dublin 515
Jacksonville 502
Chicago 266
Boardman 231
Ashburn 164
Nanjing 158
Lawrence 146
Cambridge 145
Andover 142
Toronto 136
Hefei 112
Civitanova Marche 106
Catania 90
Munich 87
Beijing 84
San Mateo 80
Abidjan 75
Houston 72
Los Angeles 70
Des Moines 69
Moscow 59
Helsinki 58
Shenyang 55
Wilmington 53
Nanchang 49
Dakar 48
Hebei 43
Seoul 43
Ho Chi Minh City 40
Saint Petersburg 40
São Paulo 31
Tianjin 30
Ottawa 27
Buffalo 25
Jiaxing 25
Changsha 22
Council Bluffs 22
Hanoi 22
New York 16
Naples 15
Atlanta 14
Bremen 14
Brooklyn 14
Seattle 13
Brussels 12
The Dalles 12
Tokyo 12
Augusta 11
Bari 11
Belo Horizonte 11
Columbus 11
Hong Kong 11
Pune 11
Amsterdam 10
Denver 10
Montreal 10
Norwalk 10
Redondo Beach 10
Rio de Janeiro 10
Ardabil 9
Johannesburg 9
Warsaw 9
Baghdad 8
Barlassina 8
Curitiba 8
Leawood 8
Washington 8
Campinas 7
Cotonou 7
Kunming 7
Phoenix 7
Stockholm 7
Zhengzhou 7
Ankara 6
Ann Arbor 6
Asunción 6
Boston 6
Brasília 6
Chennai 6
Dong Ket 6
Frankfurt Am Main 6
Haiphong 6
Jinan 6
Liberty Lake 6
Ludwigshafen 6
Mexico City 6
Mumbai 6
Poplar 6
Quito 6
Rome 6
San Francisco 6
Tashkent 6
Den Haag 5
Guangzhou 5
Hangzhou 5
London 5
Totale 7.126
Salva come PNG Salva come JPEG
Nome #
Application of PARM to constructing and comparing 5-HT1A and alfa1 receptor models 213
Lipophilic conjugates of methotrexate with short-chain alkylamino acids as DHFR inhibitors. Synthesis, biological evaluation, and molecular modeling 134
Pharmacological properties and biochemical mechanisms of MOR ligands might be due to different binding poses. MD Studies 123
Correlating in Vitro Target-Oriented Screening and Docking: Inhibition of Matrix Metalloproteinases Activities by Flavonoids 112
A 3D QSAR study of Monoamino Oxidase B inhibitors, using the chemical function based pharmacophore generation approach 104
Quantum chemical and molecular dynamics studies of MUC-1 calix[4,8]arene scaffold based anti-cancer vaccine candidates 104
5-HT1A receptors mapping by conformational analysis (2D NOESY/MM) and "tree way modelling" (HASL, CoMFA, PARM) 103
4 Methyl-2-[N-(3,4-methylenedioxy-benzylidene)hydrazino]thiazole and its reduction product, 4-methyl-2-[N-(3,4-methylenedioxybenzylidene)-hydrazono]-4,5-dihydrothiazole 103
Drug delivery of synthetic antisense “Bioconjugates” for anticancer therapy DNA. 102
Molecular modeling and biological studies show that some μ-opioid receptor agonists might elicit analgesia acting as MMP-9 inhibitors 99
A new procedure for the synthesis of 4H-pyrazolo[1,5-c][1,3,5]thiadiazine-4-thiones 95
Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity 94
Sulfonilamidothiopyrimidone and thiopyrimidone derivatives as selective COX-2 inhibitors: Synthesis, biological evaluation, and docking studies 92
16. Towards a complete picture of chiral discrimination processes by C9 carbamate derivatives of dihydroquinine: interaction mechanisms of diastereoisomeric 9-O-[(S)- or (R)-1-(1-naphthyl)ethylcarbamate]dihydroquinine and the two enantiomers of N-(3,5-dinitrobenzoyl)alanine methyl ester 92
An efficient procedure for the synthesis of Pyrazolo[3,4-d] [1,3] Thiazin-4-ones 91
Spectroscopic Investigation and Molecular Modeling on Porphyrin/PAMAM Supramolecular Adduct 89
Alkylation of non-electron rich nitrogen heterocycles by alkyl orthoformates: quantum chemistry calculations 89
5HT1a Receptor Binding Affinities of a Series of Serotonin Transporter (SERT) Inhibitors and Related Thermodynamic Insights 89
In-silico design and biological investigations of Diabetic Neuropathy modulators: could MOR become a focal mediator for this pathology? 89
Potential of Aryl-urea-Benzofuranylthiazoles hybrids as multitasking agents in Alzheimer’s disease 88
Drug Delivery of Synthetic Antisense-DNA “bioconjugates” for Anticancer Therapy 88
Identification of a novel adiponectin receptor and opioid receptor dual acting agonist as a potential treatment for diabetic neuropathy 87
TCP-FA4: A derivative of tranylcypromine showing improved blood-brain permeability 87
Pyrimido[5,4-b] Indole derivatives. 1. A new class of potent and selective alpha-1 adrenoceptor ligands 87
Application of Parm to constructing and comparing 5-HT1A and alfa1 receptor models 87
In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase 87
3D-QSAR Using ”Multiconformer” Alignment: The Use of HASL in the Analysis of 5-HT1A Thienopyrimidinone Ligands 85
Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids. I. Synthesis and biological evaluation of lipophilic conjugates of tranylcypromine 84
Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids II. Experimental and computational evidence using biomembrane models 84
Binding of imidazline ligands to the active site of purified MAO A 84
The cell cycle molecules behind neurodegeneration in Alzheimer's disease: perspectives for drug development 83
DRUG DELIVERY OF SYNTHETIC ANTISENSE-DNA "BIOCONJUGATES" FOR ANTICANCER THERAPY 83
An Alternative Method for 3D-QSAR and the Alignment of Molecular Structures: BiS (Biological Substrate Search) 83
Stereoretentive Chlorination of Cyclic Alcohols Catalyzed by Titanium (IV) Tetrachloride: Evidence for a Front Side Attack Mechanism. 82
Preparation, characterisation and photosensitivity studies of solid dispersions of diflunisal and Eudragit RS100 (R) and RL100 (R) 82
Molecular modelling of a novel class of N5-methanesulfonamide dihydrothienopyrimidinoners as potential dual COX-2 inhibitor/ 81
How to choose the suitable template for homology modelling of GPCRs: 5-HT7 receptor as a test case 80
Homology-based modeling of rhodopsin-like family members in the inactive state: structural analysis and deduction of tips for modeling and optimization. 80
Molecular modeling studies on mu opioid receptor of agonists and antagonists, endogenous and exogenous, ligands 80
Building a model of interaction at the NK-2 receptors: polycondensed heterocycles containing the pyrimidoindole skeleton 80
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases 79
Imidazole Derivatives as Heme Oxygenase-1 Inhibitors 79
Sensory Analysis on Red Wines: Discrimination by Adaptive Fuzzy Partition (AFP) 78
Exploring the biological activity of a library of 1,2,5-oxadiazole derivatives endowed with antiproliferative activity 77
5-HT1A receptor binding analysis of thienopyrimidinones partial agonists: a paradigm breaking study regarding the pharmacophoric leadership of the protonated piperazine ring in GPCR ligands 76
5-HT1A receptors mapping by conformational analysis (2D NOESY/MM) and ”three way modelling” (HASL, CoMFA, PARM) 76
Potential of alkyl orthoformates as alkylating agents of non-electron rich nitrogen heterocycles 75
Conformational analysis and pharmacophore identification of new serotonin 5-HT4 receptor ligands made by DISCO 75
Synthesis and pharmacological evaluation of benzothieno and [1]pyridothieno [2,3-d]triazole derivatives as antagonists at NK-1 receptors 75
A field-based disparity analysis of new 1,2,5- oxadiazole derivatives endowed with antiproliferative activity 75
Combining molecular modeling with experimental methodologies: mechanism of membrane permeation and accumulation of ofloxacin 75
Heterocyclic systems containing the pyrimido-2,4-dione ring as selective ligands for the alpha1-adrenoceptors 74
Application of PARM to constructing and comparing 5-HT1A and alpha1 receptor models 73
ML10302 73
Interaction of natural flavonoid eriocitrin with beta-cyclodextrin and hydroxypropyl-beta-cyclodextrin: an NMR and molecular dynamics investigation 73
Parameters for irreversible inactivation of monoamine oxidase 73
Interactions of imidazoline ligands with the active site of purified monoamine oxidase A 72
Theoretical calculations of the catalytic triad in short chain alcohol dehydrogenases/reductases 72
Structural data: the basis for molecular modelling 72
Molecular modelling and site-directed mutagenesis reveal essential residues for 5-HT7 receptor binding 72
Building a model of interaction at the NK-2 receptors: Polycondensed heterocycles containing the pyrimidoindole skeleton 72
Heme Oxygenase 1 and Heme Oxygenase 2 As Druggable Targets: Docking and Two Hybrid System To Identifying and Characterizing Protein-Proten Interactions. 71
A method for determination of form and sizes of pocket in "receptor-ligand" complexes 71
Substrate and inhibitor specificity of class 1 and class 2 histone deacetylases 70
Potential immunoregulatory role of heme oxygenase-1 in human milk: a combined biochemical and molecular modeling approach 70
Synthesis and pharmacological activity of 6H-thiazolo[3’,2’:1,2]-5-oxopyrimido[5,4-b] Indole derivatives, a new heterocyclic ring system 70
Pyrazolothiazolopyrimidine derivatives as novel class of anti-inflammatory or antinociceptive agents: synthesis, structural characterization and pharmacological evaluation 69
Crystallographic, NMR and ab initio calculation studies of tautomerism among substituted thiazol-2-yl-hydrazines 69
Synthesis and pharmacological evaluation of pyrazolopyrimidobenzoxazole and pyrazolopyrimidobenzothiazole derivatives 69
Molecular modelling of a novel class of N5-methanesulfonamide dihydrothienopyrimidinoners as as potential dual COX-2 inhibitor/nitric oxide anti-releasing agents 68
MULTIGEN: A NEW PARADIGM FOR “MULTICONFORMATIONAL” ALIGNMENT OF MOLECULAR STRUCTURES IN 3D-QSAR STUDIES 68
Peptidomimetics in Silico 68
Hydrophobic molecular similarity from MST fractional contributions to the octanol/water partition coefficient 67
Carbohydrate-Ligand Complex Binding: EMPIRICAL FREE ENERGY MODELING 67
Multi-conformational method of analysis of biological activity of molecular structures 67
Thiazole derivatives as inhibitors of purified bovine liver mitochondrial monoamine oxidase-B: structure-activity relationships and theoretical study 67
Design, synthesis and docking study of novel coumarin ligands as potential selective acetylcholinesterase inhibitors 66
Identification of essential residues for binding and activation in the human 5-HT7(a) serotonin receptor by molecular modeling and site-directed mutagenesis 66
Evaluation of Imidazole-Based Compounds as Heme Oxygenase-1 Inhibitors 66
Comparing Log P Calculations by the Ghose-Crippen and Villar Methods 65
Potential of indole skeleton containing heterocycles as antagonists at the neurokinin (NK) receptor system 65
DESIGN AND SYNTHESIS OF MULTIPLE LIGANS: NEW ARYLAMINES AND THEIR BINDING AFFINITY TOWARD 5-HT TRANSPORTER (SERT) AND 5-HT7- RECEPTORS 64
Study on new neurokinin antagonists: polycondensed heterocycles containing the indole skeleton 64
Sequential application of ligand and structure based modeling approaches to index chemicals for their hH4R antagonism 63
COMBINING NMR AND MOLECULAR MODELLING IN A DRUG DELIVERY CONTEXT: investigation of the multi-mode inclusion of a new NPY-5 antagonist bromobenzenesulfonamide into beta-cyclodextrin 63
Combined NMR-crystallographic and modelling investigation of the inclusion of molsidomine into alpha-, beta - and gamma -cyclodextrins 63
Identification of an impurity in the synthesis of pharmacologically active pyrazolotriazolopyrimidines by a combined spectrometric approach 62
Synthesis of 1-phenyl-6-arilsubstituted pyrazolopyrimidothiazole as antagonists at the NK-2 receptors 62
Potential of Pyrazolooxadiazinone Derivatives as Serine Protease Inhibitors 62
New heterocyclic ring systems. Synthesis and pharmacological activity of 6H-1,3,4-thiadiazolo [3’,2’: 1,2]-5-oxopyrimido[5,4-b]indole derivatives and of 1-phenyl-6H-1,2,4-Triazolo [1’,5’: 1,2]-5-oxopyrimido [5,4-b]Indole 62
Synthesis and pharmacological properties of pyrazolotriazolopyrimidine derivatives 61
Receptor modeling using " Multiconformer" alignment: comparison of HASL and CoMFA in the analysis of 5-HT1A thienopyrimidinone ligands 60
Docking simulation of complex between 2,5-xilidine and Rigidoporus lignosus laccase 60
Emerging antifungal azoles and effects on Magnaporthe grisea 59
STUDY OF STRUCTURAL AND DYNAMIC BEHAVIOUR OF IBUPROFEN AND ITS COMPLEXES WITH EUDRAGIT® RL100 BY NERANS OF SOLID STATE 58
PARM mapping of rat and human serotonin 1A (5-HT1A) receptor 57
How does binding of imidazole-based inhibitors to heme oxygenase-1 influence their conformation? Insights combining crystal structures and molecular modelling 57
Recent Applications of In Silico Approaches for Studying Receptor Mutations Associated with Human Pathologies 56
Computational Comparison of Imidazoline Association with the I2 Binding Site in Human Monoamine Oxidases 56
Identification of 5-Methoxyflavone as a Novel DNA Polymerase-Beta Inhibitor and Neuroprotective Agent against Beta-Amyloid Toxicity. 56
Totale 7.849
Salva come PNG Salva come JPEG
Categoria #
all - tutte 36.594
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 36.594
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021617 0 0 0 0 243 26 80 3 73 4 148 40
2021/2022996 134 148 0 15 156 5 143 25 101 0 37 232
2022/20231.593 150 55 34 120 179 291 0 305 377 6 54 22
2023/2024517 39 68 23 39 25 81 4 12 2 16 136 72
2024/20252.721 14 472 134 157 501 351 104 132 244 270 143 199
2025/20262.624 292 201 991 379 761 0 0 0 0 0 0 0
Totale 10.422