IRIS
ROMEO, Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 5.851
EU - Europa 3.248
AS - Asia 2.323
SA - Sud America 489
AF - Africa 268
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 3
Totale 12.186
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Nazione #
US - Stati Uniti d'America 5.606
SG - Singapore 1.164
IT - Italia 921
CN - Cina 849
IE - Irlanda 689
UA - Ucraina 550
BR - Brasile 453
DE - Germania 354
CA - Canada 230
RU - Federazione Russa 198
CI - Costa d'Avorio 184
FI - Finlandia 174
GB - Regno Unito 78
SE - Svezia 76
VN - Vietnam 62
IN - India 57
FR - Francia 51
SN - Senegal 48
KR - Corea 34
PL - Polonia 32
UZ - Uzbekistan 24
CH - Svizzera 23
BD - Bangladesh 20
IQ - Iraq 19
TR - Turchia 19
ES - Italia 18
NL - Olanda 17
AT - Austria 16
JP - Giappone 16
ZA - Sudafrica 14
CZ - Repubblica Ceca 13
IR - Iran 12
VE - Venezuela 11
AR - Argentina 10
GR - Grecia 10
BG - Bulgaria 8
EC - Ecuador 8
MA - Marocco 8
MX - Messico 8
HK - Hong Kong 7
ID - Indonesia 5
PK - Pakistan 5
RO - Romania 5
TN - Tunisia 5
EU - Europa 4
LT - Lituania 4
LU - Lussemburgo 4
OM - Oman 4
AE - Emirati Arabi Uniti 3
AU - Australia 3
IL - Israele 3
JO - Giordania 3
KE - Kenya 3
LB - Libano 3
NG - Nigeria 3
BE - Belgio 2
CL - Cile 2
DO - Repubblica Dominicana 2
EG - Egitto 2
KZ - Kazakistan 2
NP - Nepal 2
PH - Filippine 2
PY - Paraguay 2
SA - Arabia Saudita 2
TT - Trinidad e Tobago 2
AZ - Azerbaigian 1
BY - Bielorussia 1
CO - Colombia 1
DZ - Algeria 1
GY - Guiana 1
HN - Honduras 1
HU - Ungheria 1
JM - Giamaica 1
KG - Kirghizistan 1
KW - Kuwait 1
LV - Lettonia 1
MD - Moldavia 1
MT - Malta 1
PE - Perù 1
PS - Palestinian Territory 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
TW - Taiwan 1
Totale 12.186
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Città #
Chandler 904
Singapore 689
Dublin 687
Santa Clara 654
Jacksonville 588
Chicago 342
Boardman 309
Munich 289
Catania 250
Ashburn 238
Nanjing 202
Cambridge 191
Andover 190
Lawrence 190
Abidjan 184
Toronto 174
Helsinki 133
Civitanova Marche 130
Beijing 116
San Mateo 113
Houston 112
Dallas 111
Wilmington 95
Des Moines 86
Hefei 73
Nanchang 67
Shenyang 58
Dakar 48
Hebei 46
Los Angeles 43
Saint Petersburg 42
São Paulo 42
Tianjin 42
Jiaxing 40
The Dalles 39
Changsha 38
Columbus 38
Dong Ket 37
Council Bluffs 36
Rome 36
Ottawa 35
Seoul 33
Florence 32
Naples 28
Bremen 26
Redmond 24
Brooklyn 21
Turku 21
Moscow 20
Palermo 19
Washington 19
Belo Horizonte 18
New York 18
Pune 17
Boydton 16
Augusta 15
Seattle 15
Tokyo 15
Mumbai 14
Phoenix 14
Falls Church 13
Jinan 13
Norwalk 13
Ardabil 12
Ningbo 12
Tashkent 12
Warsaw 12
Ann Arbor 11
Jyväskylä 11
Kunming 11
Messina 11
Johannesburg 10
Leawood 10
London 10
Rio de Janeiro 10
Baghdad 9
Brasília 9
Civitavecchia 9
Hanoi 9
San Francisco 9
Den Haag 8
Liberty Lake 8
Milan 8
Osio Sotto 8
Pozzallo 8
Barcelona 7
Boston 7
Brno 7
Centro 7
Curitiba 7
Dhaka 7
Guangzhou 7
Guarulhos 7
Ho Chi Minh City 7
Padova 7
Porto Alegre 7
Siracusa 7
Zhengzhou 7
Ferrara di Monte Baldo 6
Hangzhou 6
Totale 8.481
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Nome #
(E)-alpha-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 222
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 222
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 214
[1,2,4]Triazole derivatives as 5-HT1A serotonin receptor ligands 166
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 138
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 134
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 127
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 121
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 114
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 110
A focus on Heme Oxygenase-1 (HO-1) inhibitors 106
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 103
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 99
Synthesis and binding properties of novel selective 5-HT3 receptor ligands 96
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 96
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 95
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 94
An alpha1-adrenergic receptor ligand repurposed as a potent antiproliferative agent for head and neck squamous cell carcinoma 94
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 93
3-ARILPIPERAZINILALCHILPIRROLO[3,2-d]PIRIMIDIN-2,4-DIONE: UNA NUOVA CLASSE DI LIGANDI POTENTI ED ALTAMENTE SELETTIVI PER I RECETTORI a 1-ADRENERGICI 92
Synthesis of novel 4,5-diphenylthiazole derivatives as potential acylCoA:cholesterol O-acyltransferase inhibitors 91
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 90
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 90
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 89
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 88
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 87
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 87
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 85
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 85
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 84
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 83
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 83
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 82
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 81
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 81
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 81
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 81
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 80
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 79
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 78
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective a1-adrenoceptor ligands 78
5-HT7 receptor ligands: recent developments and potential therapeutic applications 78
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 78
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 77
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 77
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 77
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 76
In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles 76
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 76
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 75
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 75
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 74
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 73
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 73
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 73
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 72
Development of [methoxy-11C]RN5 as a potential radioligand for the in vivo PET measurement of myocardial alpha1A-adrenoceptors 72
[Synthesis and antifungal activity of new derivatives of 5-(4-halobenzoyl)-4-amino-3-(2-dialkylaminoethylthio)thieno [2,3-c] and [3,2-d] isothiazole]. 72
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 72
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 72
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 71
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 71
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 71
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 70
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 70
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases 70
(E)-alfa-[[(5-Substituted)1H-indol- 3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 70
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 69
ACIDI (E)-a-[(1H-INDOL-3-IL)METILENE]BENZENEACETICI: UNA NUOVA CLASSE DI LIGANDI PER I RECETTORI DELLE ENDOTELINE 68
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 68
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 68
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 68
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 67
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 67
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 67
SINTESI DI LIGANDI SELETTIVI PER I RECETTORI alfa1-ADRENERGICI 66
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 66
Sintesi di 1,2,4 Triazoli come Ligandi per i Recettori delle Endoteline 65
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 65
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 65
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 64
Synthesis of new thieno[2,3-d]pyrimidine-(1H,3H)2,4-diones with analgesic and antiinflammatory activities 64
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 64
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 64
Synthesis and Binding Properties of New Endothelin Receptor Ligands 64
[11C]RN5: A new agent for the in vivo imaging of myocardial alpha1-adrenoceptors 64
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 64
Heterocyclic systems containing the pyrimido-2,4-dione ring as selective ligands for the alpha1-adrenoceptors 63
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 63
Design and synthesis of novel potential ligands for endothelin receptors 62
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 62
Curcumin I-SMA nanomicelles as promising therapeutic tool to tackle bacterial infections 60
Benzothieno[3,2-d]pyrimidine ligands with high affinity for human α1-adrenergic receptor subtypes 59
Arylpiperazinylalkylthio benzothiazole or benzoxazole derivatives as selective 5-HT1A serotonin receptor ligands 59
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as novel ligands for the 5-HT7 receptor 59
Synthesis and pharmacological activity of 6H-thiazolo[3’,2’:1,2]-5-oxopyrimido[5,4-b] Indole derivatives, a new heterocyclic ring system 59
Pyrazolothiazolopyrimidine derivatives as novel class of anti-inflammatory or antinociceptive agents: synthesis, structural characterization and pharmacological evaluation 58
Pyrimido[5,4-b] Indole derivatives. 1. A new class of potent and selective alpha-1 adrenoceptor ligands 58
Synthesis and endothelin receptor binding affinity of a novel class of (E)-α-[[(5-phenylmethoxy)-1H-indol-3-yl]methylene]benzeneacetic acids 58
Synthesis and pharmacological evaluation of pyrazolopyrimidobenzoxazole and pyrazolopyrimidobenzothiazole derivatives 58
Totale 8.305
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Categoria #
all - tutte 46.178
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.178
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021927 0 0 132 25 306 22 114 5 82 11 162 68
2021/20221.547 185 210 60 28 227 27 221 63 142 20 42 322
2022/20232.485 225 127 59 261 254 438 3 410 557 27 102 22
2023/20241.006 58 171 48 55 86 221 6 58 4 36 149 114
2024/20254.022 33 606 244 247 740 381 315 221 364 340 271 260
2025/2026752 480 224 48 0 0 0 0 0 0 0 0 0
Totale 12.570