IRIS
ROMEO, Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 8.808
EU - Europa 4.813
AS - Asia 4.089
SA - Sud America 731
AF - Africa 519
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 5
Totale 18.972
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Nazione #
US - Stati Uniti d'America 8.464
SG - Singapore 2.191
RU - Federazione Russa 1.324
CN - Cina 1.069
IT - Italia 985
IE - Irlanda 680
BR - Brasile 622
UA - Ucraina 546
DE - Germania 372
VN - Vietnam 287
CI - Costa d'Avorio 272
CA - Canada 270
FR - Francia 263
FI - Finlandia 184
GB - Regno Unito 122
KR - Corea 108
IN - India 103
NG - Nigeria 91
SE - Svezia 91
PL - Polonia 52
SN - Senegal 49
BD - Bangladesh 46
HK - Hong Kong 41
MX - Messico 39
ZA - Sudafrica 39
ES - Italia 38
AR - Argentina 36
IQ - Iraq 36
JP - Giappone 36
UZ - Uzbekistan 32
NL - Olanda 31
TR - Turchia 28
KE - Kenya 25
CH - Svizzera 23
MA - Marocco 18
VE - Venezuela 18
AT - Austria 17
EC - Ecuador 17
ID - Indonesia 16
IR - Iran 15
CZ - Repubblica Ceca 14
CO - Colombia 13
GR - Grecia 13
PK - Pakistan 12
JM - Giamaica 11
LT - Lituania 11
AE - Emirati Arabi Uniti 8
BG - Bulgaria 8
EG - Egitto 8
JO - Giordania 8
TN - Tunisia 8
CL - Cile 7
OM - Oman 7
PY - Paraguay 7
RO - Romania 7
AL - Albania 5
AU - Australia 5
IL - Israele 5
LB - Libano 5
NP - Nepal 5
SA - Arabia Saudita 5
BO - Bolivia 4
EU - Europa 4
LU - Lussemburgo 4
LV - Lettonia 4
MY - Malesia 4
PA - Panama 4
PH - Filippine 4
TT - Trinidad e Tobago 4
UY - Uruguay 4
BY - Bielorussia 3
DO - Repubblica Dominicana 3
DZ - Algeria 3
ET - Etiopia 3
GT - Guatemala 3
HN - Honduras 3
HU - Ungheria 3
RS - Serbia 3
XK - ???statistics.table.value.countryCode.XK??? 3
AZ - Azerbaigian 2
BE - Belgio 2
DK - Danimarca 2
DM - Dominica 2
GA - Gabon 2
KW - Kuwait 2
KZ - Kazakistan 2
MT - Malta 2
NI - Nicaragua 2
PE - Perù 2
PS - Palestinian Territory 2
SK - Slovacchia (Repubblica Slovacca) 2
SY - Repubblica araba siriana 2
BH - Bahrain 1
BJ - Benin 1
BT - Bhutan 1
CR - Costa Rica 1
CY - Cipro 1
GY - Guiana 1
KG - Kirghizistan 1
LK - Sri Lanka 1
Totale 18.965
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Città #
Dallas 1.416
Singapore 1.254
Chandler 899
Santa Clara 691
Dublin 678
San Jose 677
Jacksonville 581
Moscow 538
Ashburn 510
Chicago 347
Boardman 303
Munich 289
Abidjan 272
Catania 259
Nanjing 198
Andover 189
Cambridge 189
Lawrence 188
Toronto 186
Lauterbourg 169
Beijing 165
Helsinki 141
Civitanova Marche 128
Los Angeles 114
San Mateo 110
Seoul 107
Houston 100
Wilmington 93
Des Moines 87
Ho Chi Minh City 83
Hefei 79
São Paulo 72
New York 71
Nanchang 67
Hanoi 59
Shenyang 58
Council Bluffs 49
Dakar 49
Hebei 46
Buffalo 45
Lagos 44
Rome 42
Tianjin 42
Florence 41
Orem 41
Saint Petersburg 41
Changsha 40
Jiaxing 39
The Dalles 38
Columbus 37
Dong Ket 37
Abuja 36
Ottawa 36
Tokyo 35
Hong Kong 33
Brooklyn 31
Warsaw 30
Johannesburg 29
Naples 29
Phoenix 29
Bremen 26
Redmond 24
Belo Horizonte 23
Palermo 23
Atlanta 22
Mumbai 22
Montreal 21
Turku 21
Tashkent 19
Washington 19
Baghdad 18
Boydton 17
Pune 17
Rio de Janeiro 17
Seattle 17
Amsterdam 16
Manchester 16
Augusta 15
London 15
Milan 15
Da Nang 14
Denver 14
Frankfurt am Main 14
Poplar 14
Chennai 13
Curitiba 13
Falls Church 13
Jinan 13
Mexico City 13
Norwalk 13
Ardabil 12
Brasília 12
Dhaka 12
Jakarta 12
Redondo Beach 12
San Francisco 12
Stockholm 12
Ann Arbor 11
Jyväskylä 11
Kunming 11
Totale 12.920
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Nome #
(E)-alpha-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 316
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 299
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 295
[1,2,4]Triazole derivatives as 5-HT1A serotonin receptor ligands 233
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 200
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 193
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 191
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 188
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 186
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 177
(E)-alfa-[[(5-Substituted)1H-indol- 3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 169
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 169
A focus on Heme Oxygenase-1 (HO-1) inhibitors 164
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 159
3-ARILPIPERAZINILALCHILPIRROLO[3,2-d]PIRIMIDIN-2,4-DIONE: UNA NUOVA CLASSE DI LIGANDI POTENTI ED ALTAMENTE SELETTIVI PER I RECETTORI a 1-ADRENERGICI 157
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 156
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 156
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 156
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 151
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 149
5-HT7 receptor ligands: recent developments and potential therapeutic applications 148
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 148
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 146
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 146
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective a1-adrenoceptor ligands 144
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 143
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 141
[Synthesis and antifungal activity of new derivatives of 5-(4-halobenzoyl)-4-amino-3-(2-dialkylaminoethylthio)thieno [2,3-c] and [3,2-d] isothiazole]. 140
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 138
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 138
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 135
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 135
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 134
An alpha1-adrenergic receptor ligand repurposed as a potent antiproliferative agent for head and neck squamous cell carcinoma 134
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 134
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 133
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 132
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 132
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 128
In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles 128
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 126
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 126
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 126
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 125
Synthesis and binding properties of novel selective 5-HT3 receptor ligands 124
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 123
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 122
[11C]RN5: A new agent for the in vivo imaging of myocardial alpha1-adrenoceptors 122
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 120
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 120
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 120
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 118
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 118
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 117
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 117
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 116
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 115
Synthesis of novel 4,5-diphenylthiazole derivatives as potential acylCoA:cholesterol O-acyltransferase inhibitors 115
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 115
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 114
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 113
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 112
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 111
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 111
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 110
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 108
Curcumin I-SMA nanomicelles as promising therapeutic tool to tackle bacterial infections 107
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 107
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 106
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 105
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 103
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 102
Synthesis and Binding Properties of New Endothelin Receptor Ligands 102
[11C]RN5: un nuovo radiotracciante PET per l’imaging in vivo dei recettori alfa1-adrenergici miocardici 102
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 101
Pyrimido[5,4-b] Indole derivatives. 1. A new class of potent and selective alpha-1 adrenoceptor ligands 101
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 101
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinolinecarboxylic acid derivatives 98
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 98
Design and synthesis of novel potential ligands for endothelin receptors 96
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 95
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 95
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 95
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases 94
Synthesis and endothelin receptor binding affinity of a novel class of (E)-α-[[(5-phenylmethoxy)-1H-indol-3-yl]methylene]benzeneacetic acids 94
Heterocyclic systems containing the pyrimido-2,4-dione ring as selective ligands for the alpha1-adrenoceptors 93
Synthesis of new thieno[2,3-d]pyrimidine-(1H,3H)2,4-diones with analgesic and antiinflammatory activities 92
ACIDI (E)-a-[(1H-INDOL-3-IL)METILENE]BENZENEACETICI: UNA NUOVA CLASSE DI LIGANDI PER I RECETTORI DELLE ENDOTELINE 92
Sintesi di 1,2,4 Triazoli come Ligandi per i Recettori delle Endoteline 91
SINTESI DI LIGANDI SELETTIVI PER I RECETTORI alfa1-ADRENERGICI 91
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 91
Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for alpha1-adrenoceptor subtypes. 91
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as novel ligands for the 5-HT7 receptor 89
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 88
Synthesis and pharmacological activity of 6H-thiazolo[3’,2’:1,2]-5-oxopyrimido[5,4-b] Indole derivatives, a new heterocyclic ring system 88
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 87
Development of [methoxy-11C]RN5 as a potential radioligand for the in vivo PET measurement of myocardial alpha1A-adrenoceptors 87
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinoline carboxylic acid derivatives 86
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 86
Benzothieno[3,2-d]pyrimidine ligands with high affinity for human α1-adrenergic receptor subtypes 84
Totale 12.923
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Categoria #
all - tutte 62.626
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 62.626
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.532 183 208 60 28 224 27 220 61 140 20 42 319
2022/20232.462 223 127 59 259 250 434 3 405 552 27 101 22
2023/2024998 57 169 47 54 86 221 6 58 4 36 148 112
2024/20253.981 33 601 240 245 731 377 315 219 360 336 268 256
2025/20267.642 476 223 1.521 376 1.178 1.475 954 157 422 462 229 169
2026/202742 42 0 0 0 0 0 0 0 0 0 0 0
Totale 19.359