IRIS
ROMEO, Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 6.407
EU - Europa 3.250
AS - Asia 2.349
SA - Sud America 502
AF - Africa 270
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 3
Totale 12.785
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Nazione #
US - Stati Uniti d'America 6.160
SG - Singapore 1.164
IT - Italia 922
CN - Cina 870
IE - Irlanda 689
UA - Ucraina 550
BR - Brasile 465
DE - Germania 354
CA - Canada 230
RU - Federazione Russa 198
CI - Costa d'Avorio 184
FI - Finlandia 174
GB - Regno Unito 79
SE - Svezia 76
VN - Vietnam 64
IN - India 58
FR - Francia 51
SN - Senegal 48
KR - Corea 34
PL - Polonia 32
UZ - Uzbekistan 24
CH - Svizzera 23
BD - Bangladesh 20
TR - Turchia 20
IQ - Iraq 19
ES - Italia 18
JP - Giappone 17
NL - Olanda 17
AT - Austria 16
ZA - Sudafrica 15
CZ - Repubblica Ceca 13
IR - Iran 12
VE - Venezuela 11
AR - Argentina 10
GR - Grecia 10
EC - Ecuador 9
MX - Messico 9
BG - Bulgaria 8
MA - Marocco 8
HK - Hong Kong 7
ID - Indonesia 5
PK - Pakistan 5
RO - Romania 5
TN - Tunisia 5
EU - Europa 4
LT - Lituania 4
LU - Lussemburgo 4
OM - Oman 4
AE - Emirati Arabi Uniti 3
AU - Australia 3
IL - Israele 3
JO - Giordania 3
KE - Kenya 3
LB - Libano 3
NG - Nigeria 3
BE - Belgio 2
CL - Cile 2
DO - Repubblica Dominicana 2
EG - Egitto 2
KZ - Kazakistan 2
NP - Nepal 2
PH - Filippine 2
PY - Paraguay 2
SA - Arabia Saudita 2
TT - Trinidad e Tobago 2
AZ - Azerbaigian 1
BY - Bielorussia 1
CO - Colombia 1
DZ - Algeria 1
ET - Etiopia 1
GY - Guiana 1
HN - Honduras 1
HU - Ungheria 1
JM - Giamaica 1
KG - Kirghizistan 1
KW - Kuwait 1
LV - Lettonia 1
MD - Moldavia 1
MT - Malta 1
PA - Panama 1
PE - Perù 1
PS - Palestinian Territory 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
TW - Taiwan 1
Totale 12.785
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Città #
Chandler 904
Singapore 689
Dublin 687
Santa Clara 654
Dallas 649
Jacksonville 588
Chicago 342
Boardman 309
Munich 289
Catania 250
Ashburn 248
Nanjing 202
Cambridge 191
Andover 190
Lawrence 190
Abidjan 184
Toronto 174
Helsinki 133
Civitanova Marche 130
Beijing 116
San Mateo 113
Houston 112
Wilmington 95
Des Moines 86
Hefei 73
Nanchang 67
Shenyang 58
Dakar 48
Hebei 46
Los Angeles 44
São Paulo 44
Saint Petersburg 42
Tianjin 42
Jiaxing 40
The Dalles 39
Changsha 38
Columbus 38
Dong Ket 37
Council Bluffs 36
Rome 36
Ottawa 35
Seoul 33
Florence 32
Naples 28
Bremen 26
Redmond 24
Brooklyn 21
Turku 21
Moscow 20
Belo Horizonte 19
New York 19
Palermo 19
Washington 19
Pune 17
Boydton 16
Tokyo 16
Augusta 15
Seattle 15
Mumbai 14
Phoenix 14
Falls Church 13
Jinan 13
Norwalk 13
Ardabil 12
Ningbo 12
Tashkent 12
Warsaw 12
Ann Arbor 11
Jyväskylä 11
Kunming 11
Messina 11
Johannesburg 10
Leawood 10
London 10
Rio de Janeiro 10
Baghdad 9
Brasília 9
Civitavecchia 9
Hanoi 9
Milan 9
San Francisco 9
Curitiba 8
Den Haag 8
Guarulhos 8
Ho Chi Minh City 8
Liberty Lake 8
Osio Sotto 8
Porto Alegre 8
Pozzallo 8
Barcelona 7
Boston 7
Brno 7
Centro 7
Dhaka 7
Guangzhou 7
Padova 7
Siracusa 7
Zhengzhou 7
Atlanta 6
Ferrara di Monte Baldo 6
Totale 9.040
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Nome #
(E)-alpha-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 240
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 229
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 223
[1,2,4]Triazole derivatives as 5-HT1A serotonin receptor ligands 174
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 141
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 136
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 131
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 126
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 126
A focus on Heme Oxygenase-1 (HO-1) inhibitors 114
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 114
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 104
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 102
Synthesis and binding properties of novel selective 5-HT3 receptor ligands 101
3-ARILPIPERAZINILALCHILPIRROLO[3,2-d]PIRIMIDIN-2,4-DIONE: UNA NUOVA CLASSE DI LIGANDI POTENTI ED ALTAMENTE SELETTIVI PER I RECETTORI a 1-ADRENERGICI 99
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 99
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 98
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 98
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 97
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 97
An alpha1-adrenergic receptor ligand repurposed as a potent antiproliferative agent for head and neck squamous cell carcinoma 95
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 95
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 95
Synthesis of novel 4,5-diphenylthiazole derivatives as potential acylCoA:cholesterol O-acyltransferase inhibitors 93
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 93
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 91
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 91
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 91
(E)-alfa-[[(5-Substituted)1H-indol- 3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 90
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 90
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 88
5-HT7 receptor ligands: recent developments and potential therapeutic applications 88
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 87
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 87
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 87
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 87
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 86
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective a1-adrenoceptor ligands 86
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 84
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 84
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 83
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 83
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 82
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 82
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 81
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 81
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 81
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 80
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 80
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 80
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 79
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 79
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 77
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 77
In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles 77
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 77
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 77
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 76
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 76
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 76
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 75
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 75
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 75
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 74
[Synthesis and antifungal activity of new derivatives of 5-(4-halobenzoyl)-4-amino-3-(2-dialkylaminoethylthio)thieno [2,3-c] and [3,2-d] isothiazole]. 74
Development of [methoxy-11C]RN5 as a potential radioligand for the in vivo PET measurement of myocardial alpha1A-adrenoceptors 73
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 73
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases 72
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 72
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 71
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 71
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 71
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 71
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 71
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 70
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 69
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 69
Synthesis of new thieno[2,3-d]pyrimidine-(1H,3H)2,4-diones with analgesic and antiinflammatory activities 68
ACIDI (E)-a-[(1H-INDOL-3-IL)METILENE]BENZENEACETICI: UNA NUOVA CLASSE DI LIGANDI PER I RECETTORI DELLE ENDOTELINE 68
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 67
SINTESI DI LIGANDI SELETTIVI PER I RECETTORI alfa1-ADRENERGICI 67
Heterocyclic systems containing the pyrimido-2,4-dione ring as selective ligands for the alpha1-adrenoceptors 67
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 67
[11C]RN5: A new agent for the in vivo imaging of myocardial alpha1-adrenoceptors 67
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 67
Sintesi di 1,2,4 Triazoli come Ligandi per i Recettori delle Endoteline 66
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 66
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 66
Synthesis and Binding Properties of New Endothelin Receptor Ligands 66
Curcumin I-SMA nanomicelles as promising therapeutic tool to tackle bacterial infections 64
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinoline carboxylic acid derivatives 64
Synthesis and endothelin receptor binding affinity of a novel class of (E)-α-[[(5-phenylmethoxy)-1H-indol-3-yl]methylene]benzeneacetic acids 64
Design and synthesis of novel potential ligands for endothelin receptors 64
Synthesis and pharmacological activity of 6H-thiazolo[3’,2’:1,2]-5-oxopyrimido[5,4-b] Indole derivatives, a new heterocyclic ring system 64
Pyrimido[5,4-b] Indole derivatives. 1. A new class of potent and selective alpha-1 adrenoceptor ligands 63
Benzothieno[3,2-d]pyrimidine ligands with high affinity for human α1-adrenergic receptor subtypes 62
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as novel ligands for the 5-HT7 receptor 62
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 62
Pyrazolothiazolopyrimidine derivatives as novel class of anti-inflammatory or antinociceptive agents: synthesis, structural characterization and pharmacological evaluation 60
Arylpiperazinylalkylthio benzothiazole or benzoxazole derivatives as selective 5-HT1A serotonin receptor ligands 60
Totale 8.738
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Categoria #
all - tutte 47.515
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 47.515
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021927 0 0 132 25 306 22 114 5 82 11 162 68
2021/20221.547 185 210 60 28 227 27 221 63 142 20 42 322
2022/20232.485 225 127 59 261 254 438 3 410 557 27 102 22
2023/20241.006 58 171 48 55 86 221 6 58 4 36 149 114
2024/20254.022 33 606 244 247 740 381 315 221 364 340 271 260
2025/20261.351 480 224 647 0 0 0 0 0 0 0 0 0
Totale 13.169