IRIS
ROMEO, Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 7.600
EU - Europa 4.455
AS - Asia 3.419
SA - Sud America 617
AF - Africa 375
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 3
Totale 16.474
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Nazione #
US - Stati Uniti d'America 7.329
SG - Singapore 1.970
RU - Federazione Russa 1.330
CN - Cina 987
IT - Italia 925
IE - Irlanda 690
BR - Brasile 556
UA - Ucraina 551
DE - Germania 356
CI - Costa d'Avorio 272
CA - Canada 240
FI - Finlandia 175
VN - Vietnam 139
GB - Regno Unito 98
SE - Svezia 82
IN - India 74
FR - Francia 54
SN - Senegal 48
PL - Polonia 43
KR - Corea 37
JP - Giappone 35
ES - Italia 28
BD - Bangladesh 24
IQ - Iraq 24
NL - Olanda 24
UZ - Uzbekistan 24
AR - Argentina 23
CH - Svizzera 23
ZA - Sudafrica 23
MX - Messico 21
TR - Turchia 21
HK - Hong Kong 17
AT - Austria 16
IR - Iran 14
CZ - Repubblica Ceca 13
EC - Ecuador 13
ID - Indonesia 12
MA - Marocco 11
VE - Venezuela 11
GR - Grecia 10
BG - Bulgaria 8
LT - Lituania 8
EG - Egitto 6
PK - Pakistan 5
RO - Romania 5
TN - Tunisia 5
AE - Emirati Arabi Uniti 4
CL - Cile 4
EU - Europa 4
IL - Israele 4
JO - Giordania 4
KE - Kenya 4
LU - Lussemburgo 4
OM - Oman 4
PY - Paraguay 4
AU - Australia 3
CO - Colombia 3
DO - Repubblica Dominicana 3
LB - Libano 3
NG - Nigeria 3
NP - Nepal 3
AL - Albania 2
BE - Belgio 2
BY - Bielorussia 2
KZ - Kazakistan 2
LV - Lettonia 2
PH - Filippine 2
SA - Arabia Saudita 2
TT - Trinidad e Tobago 2
AZ - Azerbaigian 1
BH - Bahrain 1
BJ - Benin 1
DZ - Algeria 1
ET - Etiopia 1
GT - Guatemala 1
GY - Guiana 1
HN - Honduras 1
HU - Ungheria 1
JM - Giamaica 1
KG - Kirghizistan 1
KW - Kuwait 1
MD - Moldavia 1
MT - Malta 1
MY - Malesia 1
PA - Panama 1
PE - Perù 1
PS - Palestinian Territory 1
RS - Serbia 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
TW - Taiwan 1
UY - Uruguay 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 16.474
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Città #
Dallas 1.421
Singapore 1.097
Chandler 904
Dublin 688
Santa Clara 664
Jacksonville 588
Moscow 540
Ashburn 353
Chicago 343
Boardman 309
Munich 289
Abidjan 272
Catania 250
Nanjing 202
Cambridge 191
Andover 190
Lawrence 190
Toronto 178
Beijing 154
Helsinki 133
Civitanova Marche 130
Houston 118
San Mateo 113
Los Angeles 95
Wilmington 95
Des Moines 86
Hefei 80
Nanchang 67
Shenyang 58
São Paulo 56
Dakar 48
Hebei 46
Tianjin 43
New York 42
Saint Petersburg 42
Jiaxing 40
Changsha 39
The Dalles 39
Columbus 38
Dong Ket 37
Council Bluffs 36
Rome 36
Seoul 36
Buffalo 35
Ottawa 35
Ho Chi Minh City 34
Tokyo 34
Florence 32
Hanoi 30
Naples 28
Brooklyn 27
Bremen 26
Redmond 24
San Jose 23
Turku 21
Warsaw 21
Belo Horizonte 19
Mumbai 19
Palermo 19
Phoenix 19
Washington 19
Pune 17
Seattle 17
Boydton 16
Johannesburg 16
Orem 16
Augusta 15
Hong Kong 15
Atlanta 13
Falls Church 13
Jinan 13
Norwalk 13
Ardabil 12
Baghdad 12
Montreal 12
Ningbo 12
Redondo Beach 12
Rio de Janeiro 12
Tashkent 12
Amsterdam 11
Ann Arbor 11
Brasília 11
Curitiba 11
Jakarta 11
Jyväskylä 11
Kunming 11
London 11
Messina 11
Milan 11
Poplar 11
Chennai 10
Leawood 10
Manchester 10
Civitavecchia 9
Porto Alegre 9
San Francisco 9
Boston 8
Den Haag 8
Denver 8
Dhaka 8
Totale 11.299
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Nome #
(E)-alpha-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 293
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 278
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 272
[1,2,4]Triazole derivatives as 5-HT1A serotonin receptor ligands 211
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 179
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 170
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 166
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 162
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 159
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 155
(E)-alfa-[[(5-Substituted)1H-indol- 3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 149
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 147
A focus on Heme Oxygenase-1 (HO-1) inhibitors 142
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 140
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 136
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 134
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 133
3-ARILPIPERAZINILALCHILPIRROLO[3,2-d]PIRIMIDIN-2,4-DIONE: UNA NUOVA CLASSE DI LIGANDI POTENTI ED ALTAMENTE SELETTIVI PER I RECETTORI a 1-ADRENERGICI 133
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 132
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 129
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 128
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective a1-adrenoceptor ligands 126
5-HT7 receptor ligands: recent developments and potential therapeutic applications 126
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 125
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 124
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 123
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 121
An alpha1-adrenergic receptor ligand repurposed as a potent antiproliferative agent for head and neck squamous cell carcinoma 121
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 120
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 119
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 118
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 117
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 116
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 116
Synthesis and binding properties of novel selective 5-HT3 receptor ligands 115
[Synthesis and antifungal activity of new derivatives of 5-(4-halobenzoyl)-4-amino-3-(2-dialkylaminoethylthio)thieno [2,3-c] and [3,2-d] isothiazole]. 114
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 114
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 112
In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles 112
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 112
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 112
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 111
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 111
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 110
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 108
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 108
Synthesis of novel 4,5-diphenylthiazole derivatives as potential acylCoA:cholesterol O-acyltransferase inhibitors 107
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 106
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 106
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 106
[11C]RN5: A new agent for the in vivo imaging of myocardial alpha1-adrenoceptors 105
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 104
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 103
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 103
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 101
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 100
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 99
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 99
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 98
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 97
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 97
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 96
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 95
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 95
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 95
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 94
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 93
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 91
Pyrimido[5,4-b] Indole derivatives. 1. A new class of potent and selective alpha-1 adrenoceptor ligands 91
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 91
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 90
Curcumin I-SMA nanomicelles as promising therapeutic tool to tackle bacterial infections 89
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 88
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 88
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 88
[11C]RN5: un nuovo radiotracciante PET per l’imaging in vivo dei recettori alfa1-adrenergici miocardici 88
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 86
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 86
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinolinecarboxylic acid derivatives 85
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 85
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 84
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases 83
Synthesis and Binding Properties of New Endothelin Receptor Ligands 83
Development of [methoxy-11C]RN5 as a potential radioligand for the in vivo PET measurement of myocardial alpha1A-adrenoceptors 80
Synthesis of new thieno[2,3-d]pyrimidine-(1H,3H)2,4-diones with analgesic and antiinflammatory activities 80
Synthesis and endothelin receptor binding affinity of a novel class of (E)-α-[[(5-phenylmethoxy)-1H-indol-3-yl]methylene]benzeneacetic acids 80
SINTESI DI LIGANDI SELETTIVI PER I RECETTORI alfa1-ADRENERGICI 79
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 78
ACIDI (E)-a-[(1H-INDOL-3-IL)METILENE]BENZENEACETICI: UNA NUOVA CLASSE DI LIGANDI PER I RECETTORI DELLE ENDOTELINE 78
Heterocyclic systems containing the pyrimido-2,4-dione ring as selective ligands for the alpha1-adrenoceptors 78
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 78
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 77
Sintesi di 1,2,4 Triazoli come Ligandi per i Recettori delle Endoteline 76
Design and synthesis of novel potential ligands for endothelin receptors 76
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 76
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as novel ligands for the 5-HT7 receptor 73
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 73
Synthesis and pharmacological activity of 6H-thiazolo[3’,2’:1,2]-5-oxopyrimido[5,4-b] Indole derivatives, a new heterocyclic ring system 73
Pyrazolothiazolopyrimidine derivatives as novel class of anti-inflammatory or antinociceptive agents: synthesis, structural characterization and pharmacological evaluation 72
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinoline carboxylic acid derivatives 72
Totale 11.253
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Categoria #
all - tutte 54.782
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 54.782
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021464 0 0 0 0 0 22 114 5 82 11 162 68
2021/20221.547 185 210 60 28 227 27 221 63 142 20 42 322
2022/20232.485 225 127 59 261 254 438 3 410 557 27 102 22
2023/20241.006 58 171 48 55 86 221 6 58 4 36 149 114
2024/20254.022 33 606 244 247 740 381 315 221 364 340 271 260
2025/20265.040 480 224 1.538 377 1.187 1.234 0 0 0 0 0 0
Totale 16.858