IRIS
ROMEO, Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 7.539
EU - Europa 3.469
AS - Asia 3.321
SA - Sud America 614
AF - Africa 375
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 3
Totale 15.326
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Nazione #
US - Stati Uniti d'America 7.274
SG - Singapore 1.887
CN - Cina 983
IT - Italia 925
IE - Irlanda 690
BR - Brasile 554
UA - Ucraina 551
RU - Federazione Russa 360
DE - Germania 354
CI - Costa d'Avorio 272
CA - Canada 236
FI - Finlandia 175
VN - Vietnam 135
GB - Regno Unito 96
SE - Svezia 80
IN - India 74
FR - Francia 54
SN - Senegal 48
PL - Polonia 39
KR - Corea 37
JP - Giappone 33
ES - Italia 25
IQ - Iraq 24
UZ - Uzbekistan 24
BD - Bangladesh 23
CH - Svizzera 23
ZA - Sudafrica 23
AR - Argentina 22
NL - Olanda 22
TR - Turchia 21
MX - Messico 19
AT - Austria 16
IR - Iran 14
CZ - Repubblica Ceca 13
EC - Ecuador 13
HK - Hong Kong 13
ID - Indonesia 12
MA - Marocco 11
VE - Venezuela 11
GR - Grecia 10
BG - Bulgaria 8
LT - Lituania 7
EG - Egitto 6
PK - Pakistan 5
RO - Romania 5
TN - Tunisia 5
AE - Emirati Arabi Uniti 4
CL - Cile 4
EU - Europa 4
IL - Israele 4
JO - Giordania 4
KE - Kenya 4
LU - Lussemburgo 4
OM - Oman 4
PY - Paraguay 4
AU - Australia 3
CO - Colombia 3
DO - Repubblica Dominicana 3
LB - Libano 3
NG - Nigeria 3
NP - Nepal 3
AL - Albania 2
BE - Belgio 2
BY - Bielorussia 2
KZ - Kazakistan 2
LV - Lettonia 2
PH - Filippine 2
SA - Arabia Saudita 2
TT - Trinidad e Tobago 2
AZ - Azerbaigian 1
BH - Bahrain 1
BJ - Benin 1
DZ - Algeria 1
ET - Etiopia 1
GT - Guatemala 1
GY - Guiana 1
HN - Honduras 1
HU - Ungheria 1
JM - Giamaica 1
KG - Kirghizistan 1
KW - Kuwait 1
MD - Moldavia 1
MT - Malta 1
MY - Malesia 1
PA - Panama 1
PE - Perù 1
PS - Palestinian Territory 1
RS - Serbia 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
TW - Taiwan 1
UY - Uruguay 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 15.326
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Città #
Dallas 1.420
Singapore 1.016
Chandler 904
Dublin 688
Santa Clara 663
Jacksonville 588
Ashburn 345
Chicago 343
Boardman 309
Munich 289
Abidjan 272
Catania 250
Nanjing 202
Cambridge 191
Andover 190
Lawrence 190
Toronto 175
Beijing 154
Helsinki 133
Civitanova Marche 130
Houston 118
San Mateo 113
Moscow 104
Wilmington 95
Los Angeles 93
Des Moines 86
Hefei 80
Nanchang 67
Shenyang 58
São Paulo 56
Dakar 48
Hebei 46
Tianjin 43
Saint Petersburg 42
Jiaxing 40
Changsha 39
New York 39
The Dalles 39
Columbus 38
Dong Ket 37
Council Bluffs 36
Rome 36
Seoul 36
Buffalo 35
Ottawa 35
Ho Chi Minh City 33
Florence 32
Tokyo 32
Hanoi 28
Naples 28
Bremen 26
Brooklyn 26
Redmond 24
Turku 21
Belo Horizonte 19
Mumbai 19
Palermo 19
Phoenix 19
Washington 19
Pune 17
Seattle 17
Warsaw 17
Boydton 16
Johannesburg 16
Augusta 15
Falls Church 13
Jinan 13
Norwalk 13
Ardabil 12
Baghdad 12
Ningbo 12
Orem 12
Redondo Beach 12
Rio de Janeiro 12
Tashkent 12
Ann Arbor 11
Atlanta 11
Brasília 11
Curitiba 11
Hong Kong 11
Jakarta 11
Jyväskylä 11
Kunming 11
London 11
Messina 11
Milan 11
Montreal 11
Amsterdam 10
Chennai 10
Leawood 10
Manchester 10
Civitavecchia 9
Poplar 9
Porto Alegre 9
San Francisco 9
Boston 8
Den Haag 8
Guangzhou 8
Guarulhos 8
Liberty Lake 8
Totale 10.725
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Nome #
(E)-alpha-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 275
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 255
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 254
[1,2,4]Triazole derivatives as 5-HT1A serotonin receptor ligands 194
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 161
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 152
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 151
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 145
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 143
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 142
A focus on Heme Oxygenase-1 (HO-1) inhibitors 130
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 128
(E)-alfa-[[(5-Substituted)1H-indol- 3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 127
3-ARILPIPERAZINILALCHILPIRROLO[3,2-d]PIRIMIDIN-2,4-DIONE: UNA NUOVA CLASSE DI LIGANDI POTENTI ED ALTAMENTE SELETTIVI PER I RECETTORI a 1-ADRENERGICI 121
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 121
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 119
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 119
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 117
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 114
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 114
Synthesis and binding properties of novel selective 5-HT3 receptor ligands 112
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 112
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective a1-adrenoceptor ligands 112
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 111
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 110
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 109
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 109
5-HT7 receptor ligands: recent developments and potential therapeutic applications 109
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 108
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 108
An alpha1-adrenergic receptor ligand repurposed as a potent antiproliferative agent for head and neck squamous cell carcinoma 107
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 106
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 105
Synthesis of novel 4,5-diphenylthiazole derivatives as potential acylCoA:cholesterol O-acyltransferase inhibitors 104
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 104
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 104
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 104
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 103
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 102
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 102
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 102
In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles 101
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 101
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 100
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 99
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 97
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 96
[Synthesis and antifungal activity of new derivatives of 5-(4-halobenzoyl)-4-amino-3-(2-dialkylaminoethylthio)thieno [2,3-c] and [3,2-d] isothiazole]. 95
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 95
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 95
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 94
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 94
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 93
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 93
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 93
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 92
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 90
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 90
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 90
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 90
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 90
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 89
[11C]RN5: A new agent for the in vivo imaging of myocardial alpha1-adrenoceptors 89
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 89
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 88
Pyrimido[5,4-b] Indole derivatives. 1. A new class of potent and selective alpha-1 adrenoceptor ligands 87
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 87
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 87
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 86
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 86
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 85
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 85
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 84
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 84
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 83
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 83
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 82
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 81
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases 81
Development of [methoxy-11C]RN5 as a potential radioligand for the in vivo PET measurement of myocardial alpha1A-adrenoceptors 79
Synthesis and Binding Properties of New Endothelin Receptor Ligands 79
Synthesis and endothelin receptor binding affinity of a novel class of (E)-α-[[(5-phenylmethoxy)-1H-indol-3-yl]methylene]benzeneacetic acids 78
Synthesis of new thieno[2,3-d]pyrimidine-(1H,3H)2,4-diones with analgesic and antiinflammatory activities 77
ACIDI (E)-a-[(1H-INDOL-3-IL)METILENE]BENZENEACETICI: UNA NUOVA CLASSE DI LIGANDI PER I RECETTORI DELLE ENDOTELINE 77
SINTESI DI LIGANDI SELETTIVI PER I RECETTORI alfa1-ADRENERGICI 77
Curcumin I-SMA nanomicelles as promising therapeutic tool to tackle bacterial infections 76
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinolinecarboxylic acid derivatives 76
Heterocyclic systems containing the pyrimido-2,4-dione ring as selective ligands for the alpha1-adrenoceptors 76
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 76
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 75
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 75
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 75
[11C]RN5: un nuovo radiotracciante PET per l’imaging in vivo dei recettori alfa1-adrenergici miocardici 75
Design and synthesis of novel potential ligands for endothelin receptors 74
Sintesi di 1,2,4 Triazoli come Ligandi per i Recettori delle Endoteline 73
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 72
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as novel ligands for the 5-HT7 receptor 71
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinoline carboxylic acid derivatives 70
Synthesis and pharmacological activity of 6H-thiazolo[3’,2’:1,2]-5-oxopyrimido[5,4-b] Indole derivatives, a new heterocyclic ring system 70
Pyrazolothiazolopyrimidine derivatives as novel class of anti-inflammatory or antinociceptive agents: synthesis, structural characterization and pharmacological evaluation 69
Totale 10.319
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Categoria #
all - tutte 52.915
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 52.915
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021464 0 0 0 0 0 22 114 5 82 11 162 68
2021/20221.547 185 210 60 28 227 27 221 63 142 20 42 322
2022/20232.485 225 127 59 261 254 438 3 410 557 27 102 22
2023/20241.006 58 171 48 55 86 221 6 58 4 36 149 114
2024/20254.022 33 606 244 247 740 381 315 221 364 340 271 260
2025/20263.892 480 224 1.538 377 1.187 86 0 0 0 0 0 0
Totale 15.710