IRIS
ROMEO, Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 3.783
EU - Europa 2.393
AS - Asia 737
AF - Africa 235
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 3
SA - Sud America 2
Totale 7.157
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Nazione #
US - Stati Uniti d'America 3.575
IE - Irlanda 688
IT - Italia 637
CN - Cina 601
UA - Ucraina 544
CA - Canada 208
CI - Costa d'Avorio 184
RU - Federazione Russa 183
SE - Svezia 74
DE - Germania 60
GB - Regno Unito 49
SN - Senegal 48
VN - Vietnam 44
FR - Francia 43
IN - India 36
CH - Svizzera 23
PL - Polonia 21
SG - Singapore 15
NL - Olanda 14
AT - Austria 13
IR - Iran 12
UZ - Uzbekistan 12
GR - Grecia 10
BG - Bulgaria 8
ES - Italia 6
CZ - Repubblica Ceca 5
RO - Romania 5
EU - Europa 4
LU - Lussemburgo 4
AU - Australia 3
FI - Finlandia 3
JP - Giappone 3
TR - Turchia 3
BE - Belgio 2
CL - Cile 2
HK - Hong Kong 2
LB - Libano 2
NG - Nigeria 2
PH - Filippine 2
BD - Bangladesh 1
BY - Bielorussia 1
EG - Egitto 1
IL - Israele 1
IQ - Iraq 1
KR - Corea 1
TW - Taiwan 1
Totale 7.157
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Città #
Chandler 904
Dublin 687
Jacksonville 588
Catania 207
Nanjing 202
Cambridge 191
Andover 190
Lawrence 190
Abidjan 184
Ashburn 184
Toronto 171
San Mateo 113
Houston 111
Wilmington 95
Boardman 87
Des Moines 86
Nanchang 67
Shenyang 58
Dakar 48
Hebei 46
Saint Petersburg 42
Tianjin 42
Jiaxing 40
Changsha 38
Dong Ket 37
Ottawa 35
Florence 28
Bremen 26
Redmond 24
Rome 23
Moscow 19
Palermo 18
Washington 18
Boydton 16
Pune 16
Augusta 15
Falls Church 13
Jinan 13
Norwalk 13
Ardabil 12
Ningbo 12
Seattle 12
Ann Arbor 11
Beijing 11
Kunming 11
Leawood 10
Civitavecchia 9
Messina 9
Den Haag 8
Liberty Lake 8
Mumbai 8
Naples 8
Centro 7
Hanoi 7
Los Angeles 7
Padova 7
Siracusa 7
Ferrara di Monte Baldo 6
Hangzhou 6
Redwood City 6
Zhengzhou 6
Edinburgh 5
Fairfield 5
Gela 5
Guangzhou 5
Latina 5
Reggio Calabria 5
Castelvetrano 4
Cergy 4
Frankfurt Am Main 4
Lanzhou 4
Ludwigshafen 4
Madrid 4
Mountain View 4
New Delhi 4
Paris 4
Sofia 4
Taizhou 4
Tappahannock 4
Vicenza 4
Amsterdam 3
Bucharest 3
Changchun 3
Ferrara 3
Frankfurt am Main 3
Grafing 3
Gravina di Catania 3
Gunzenhausen 3
Lappeenranta 3
Lucca 3
Luxembourg 3
Mascalucia 3
Milan 3
Monmouth Junction 3
New Haven 3
New York 3
Novara 3
Orlando 3
Philadelphia 3
Rimini 3
Totale 5.215
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Nome #
[1,2,4]Triazole derivatives as 5-HT1A serotonin receptor ligands 116
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 105
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 80
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 80
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 74
Synthesis and binding properties of novel selective 5-HT3 receptor ligands 67
An alpha1-adrenergic receptor ligand repurposed as a potent antiproliferative agent for head and neck squamous cell carcinoma 66
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 66
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 64
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 63
Synthesis of novel 4,5-diphenylthiazole derivatives as potential acylCoA:cholesterol O-acyltransferase inhibitors 62
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 62
3-ARILPIPERAZINILALCHILPIRROLO[3,2-d]PIRIMIDIN-2,4-DIONE: UNA NUOVA CLASSE DI LIGANDI POTENTI ED ALTAMENTE SELETTIVI PER I RECETTORI a 1-ADRENERGICI 61
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 61
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 61
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 60
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 60
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 58
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 57
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 56
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 56
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 54
Development of [methoxy-11C]RN5 as a potential radioligand for the in vivo PET measurement of myocardial alpha1A-adrenoceptors 53
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 53
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 53
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 53
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 52
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 52
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases 51
(E)-alpha-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 50
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 50
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 50
5-HT7 receptor ligands: recent developments and potential therapeutic applications 49
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 49
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 49
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 48
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 48
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 48
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective a1-adrenoceptor ligands 48
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 48
A focus on Heme Oxygenase-1 (HO-1) inhibitors 47
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 47
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 47
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 47
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 46
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 46
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 45
ACIDI (E)-a-[(1H-INDOL-3-IL)METILENE]BENZENEACETICI: UNA NUOVA CLASSE DI LIGANDI PER I RECETTORI DELLE ENDOTELINE 45
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 45
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 45
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 45
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 44
Sintesi di 1,2,4 Triazoli come Ligandi per i Recettori delle Endoteline 44
Design and synthesis of novel potential ligands for endothelin receptors 44
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 44
Synthesis of new thieno[2,3-d]pyrimidine-(1H,3H)2,4-diones with analgesic and antiinflammatory activities 43
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 43
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 43
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 43
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 42
SINTESI DI LIGANDI SELETTIVI PER I RECETTORI alfa1-ADRENERGICI 42
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 42
In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles 42
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 42
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 42
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 41
[Synthesis and antifungal activity of new derivatives of 5-(4-halobenzoyl)-4-amino-3-(2-dialkylaminoethylthio)thieno [2,3-c] and [3,2-d] isothiazole]. 41
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 41
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 41
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 41
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 41
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinoline carboxylic acid derivatives 40
Design and Synthesis of New 3-Aryl-5-oxoprolines as Potential Ligands for Human Cloned Endothelin Receptors 40
Arylpiperazinylalkylthio benzothiazole or benzoxazole derivatives as selective 5-HT1A serotonin receptor ligands 40
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 40
Synthesis and pharmacological activity of 6H-thiazolo[3’,2’:1,2]-5-oxopyrimido[5,4-b] Indole derivatives, a new heterocyclic ring system 40
Pyrazolothiazolopyrimidine derivatives as novel class of anti-inflammatory or antinociceptive agents: synthesis, structural characterization and pharmacological evaluation 39
Synthesis and endothelin receptor binding affinity of a novel class of (E)-α-[[(5-phenylmethoxy)-1H-indol-3-yl]methylene]benzeneacetic acids 39
Benzothieno[3,2-d]pyrimidine ligands with high affinity for human α1-adrenergic receptor subtypes 39
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as novel ligands for the 5-HT7 receptor 39
Synthesis and Binding Properties of New Endothelin Receptor Ligands 39
[11C]RN5: A new agent for the in vivo imaging of myocardial alpha1-adrenoceptors 39
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 39
Pyrimido[5,4-b] Indole derivatives. 1. A new class of potent and selective alpha-1 adrenoceptor ligands 38
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 38
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 38
PROGRESS IN THE DEVELOPMENT OF SELECTIVE NITRIC OXIDE SYNTHASE (NOS) INHIBITORS 38
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 38
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 38
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 37
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 37
Design and Synthesis of Novel Potential Ligands for Endothelin Receptors 37
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 37
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 37
Heterocyclic systems containing the pyrimido-2,4-dione ring as selective ligands for the alpha1-adrenoceptors 36
Acidi (E)-[(1H-Indol-3-il)metilene]benzeneacetici: una Nuova Classe di Ligandi per i Recettori delle Endoteline 36
Novel arylpiperazine ligands with high affinity for alpha1-adrenergic receptor subtypes 36
New Piperidin-2,6-dione Derivatives as Ligands for the alpha1-Adrenoceptor Subtypes 36
Thieno[3,2-d]pyrimidine as a scaffold for 5-HT7 receptor ligands 36
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 36
Totale 4.846
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Categoria #
all - tutte 23.599
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 23.599
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201927 0 0 0 0 0 0 0 0 0 0 1 26
2019/20201.129 409 90 90 25 98 31 73 2 109 44 117 41
2020/20211.036 7 102 132 25 306 22 114 5 82 11 162 68
2021/20221.547 185 210 60 28 227 27 221 63 142 20 42 322
2022/20232.485 225 127 59 261 254 438 3 410 557 27 102 22
2023/2024743 58 171 48 55 86 221 6 58 4 36 0 0
Totale 7.533