IRIS
ROMEO, Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 7.725
EU - Europa 4.471
AS - Asia 3.465
SA - Sud America 618
AF - Africa 394
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 3
Totale 16.681
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Nazione #
US - Stati Uniti d'America 7.448
SG - Singapore 2.001
RU - Federazione Russa 1.330
CN - Cina 994
IT - Italia 925
IE - Irlanda 690
BR - Brasile 557
UA - Ucraina 551
DE - Germania 356
CI - Costa d'Avorio 272
CA - Canada 245
FI - Finlandia 175
VN - Vietnam 139
GB - Regno Unito 103
SE - Svezia 85
IN - India 79
FR - Francia 54
SN - Senegal 48
PL - Polonia 47
JP - Giappone 37
KR - Corea 37
ES - Italia 31
ZA - Sudafrica 28
BD - Bangladesh 25
IQ - Iraq 24
NL - Olanda 24
UZ - Uzbekistan 24
AR - Argentina 23
CH - Svizzera 23
MX - Messico 21
TR - Turchia 21
KE - Kenya 18
HK - Hong Kong 17
AT - Austria 16
IR - Iran 14
CZ - Repubblica Ceca 13
EC - Ecuador 13
ID - Indonesia 12
MA - Marocco 11
VE - Venezuela 11
GR - Grecia 10
LT - Lituania 9
BG - Bulgaria 8
EG - Egitto 6
PK - Pakistan 5
RO - Romania 5
TN - Tunisia 5
AE - Emirati Arabi Uniti 4
CL - Cile 4
EU - Europa 4
IL - Israele 4
JO - Giordania 4
LU - Lussemburgo 4
OM - Oman 4
PY - Paraguay 4
AU - Australia 3
CO - Colombia 3
DO - Repubblica Dominicana 3
LB - Libano 3
NG - Nigeria 3
NP - Nepal 3
AL - Albania 2
BE - Belgio 2
BY - Bielorussia 2
KZ - Kazakistan 2
LV - Lettonia 2
PH - Filippine 2
SA - Arabia Saudita 2
TT - Trinidad e Tobago 2
AZ - Azerbaigian 1
BH - Bahrain 1
BJ - Benin 1
DM - Dominica 1
DZ - Algeria 1
ET - Etiopia 1
GT - Guatemala 1
GY - Guiana 1
HN - Honduras 1
HU - Ungheria 1
JM - Giamaica 1
KG - Kirghizistan 1
KW - Kuwait 1
MD - Moldavia 1
MT - Malta 1
MY - Malesia 1
PA - Panama 1
PE - Perù 1
PS - Palestinian Territory 1
RS - Serbia 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
TW - Taiwan 1
UY - Uruguay 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 16.681
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Città #
Dallas 1.423
Singapore 1.128
Chandler 904
Dublin 688
Santa Clara 664
Jacksonville 588
Moscow 540
Ashburn 392
Chicago 344
Boardman 309
Munich 289
Abidjan 272
Catania 250
Nanjing 202
Cambridge 191
Andover 190
Lawrence 190
Toronto 180
Beijing 154
Helsinki 133
Civitanova Marche 130
Houston 120
San Mateo 113
Los Angeles 101
Wilmington 95
Des Moines 86
Hefei 80
Nanchang 67
Shenyang 58
São Paulo 57
New York 53
Dakar 48
Hebei 46
Tianjin 43
Saint Petersburg 42
Jiaxing 40
Changsha 39
The Dalles 39
Columbus 38
Dong Ket 37
Council Bluffs 36
Rome 36
Seoul 36
Tokyo 36
Buffalo 35
Ottawa 35
Ho Chi Minh City 34
Florence 32
Brooklyn 31
Hanoi 30
Naples 28
Bremen 26
San Jose 25
Warsaw 25
Phoenix 24
Redmond 24
Johannesburg 21
Turku 21
Mumbai 20
Belo Horizonte 19
Orem 19
Palermo 19
Washington 19
Pune 17
Seattle 17
Boydton 16
Atlanta 15
Augusta 15
Hong Kong 15
Montreal 14
Falls Church 13
Jinan 13
London 13
Norwalk 13
Ardabil 12
Baghdad 12
Denver 12
Manchester 12
Ningbo 12
Poplar 12
Redondo Beach 12
Rio de Janeiro 12
Tashkent 12
Amsterdam 11
Ann Arbor 11
Brasília 11
Chennai 11
Curitiba 11
Jakarta 11
Jyväskylä 11
Kunming 11
Messina 11
Milan 11
Stockholm 11
Leawood 10
Civitavecchia 9
New Delhi 9
Porto Alegre 9
San Francisco 9
Boston 8
Totale 11.438
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Nome #
(E)-alpha-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 294
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 279
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 273
[1,2,4]Triazole derivatives as 5-HT1A serotonin receptor ligands 213
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 180
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 171
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 168
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 163
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 160
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 157
(E)-alfa-[[(5-Substituted)1H-indol- 3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 150
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 149
A focus on Heme Oxygenase-1 (HO-1) inhibitors 144
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 141
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 137
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 136
3-ARILPIPERAZINILALCHILPIRROLO[3,2-d]PIRIMIDIN-2,4-DIONE: UNA NUOVA CLASSE DI LIGANDI POTENTI ED ALTAMENTE SELETTIVI PER I RECETTORI a 1-ADRENERGICI 135
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 134
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 133
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 131
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 130
5-HT7 receptor ligands: recent developments and potential therapeutic applications 128
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective a1-adrenoceptor ligands 127
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 126
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 126
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 124
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 122
An alpha1-adrenergic receptor ligand repurposed as a potent antiproliferative agent for head and neck squamous cell carcinoma 122
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 121
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 120
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 120
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 118
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 117
[Synthesis and antifungal activity of new derivatives of 5-(4-halobenzoyl)-4-amino-3-(2-dialkylaminoethylthio)thieno [2,3-c] and [3,2-d] isothiazole]. 117
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 117
Synthesis and binding properties of novel selective 5-HT3 receptor ligands 115
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 115
In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles 114
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 114
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 113
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 113
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 112
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 112
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 111
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 110
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 109
Synthesis of novel 4,5-diphenylthiazole derivatives as potential acylCoA:cholesterol O-acyltransferase inhibitors 108
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 108
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 107
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 107
[11C]RN5: A new agent for the in vivo imaging of myocardial alpha1-adrenoceptors 106
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 105
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 104
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 104
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 102
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 101
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 100
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 100
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 99
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 99
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 98
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 97
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 97
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 96
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 96
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 95
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 94
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 92
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 92
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 92
Pyrimido[5,4-b] Indole derivatives. 1. A new class of potent and selective alpha-1 adrenoceptor ligands 91
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 91
Curcumin I-SMA nanomicelles as promising therapeutic tool to tackle bacterial infections 90
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 89
[11C]RN5: un nuovo radiotracciante PET per l’imaging in vivo dei recettori alfa1-adrenergici miocardici 89
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 88
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 88
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinolinecarboxylic acid derivatives 86
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 86
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 86
Synthesis and Binding Properties of New Endothelin Receptor Ligands 85
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 84
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases 83
Synthesis of new thieno[2,3-d]pyrimidine-(1H,3H)2,4-diones with analgesic and antiinflammatory activities 81
Synthesis and endothelin receptor binding affinity of a novel class of (E)-α-[[(5-phenylmethoxy)-1H-indol-3-yl]methylene]benzeneacetic acids 81
Development of [methoxy-11C]RN5 as a potential radioligand for the in vivo PET measurement of myocardial alpha1A-adrenoceptors 80
SINTESI DI LIGANDI SELETTIVI PER I RECETTORI alfa1-ADRENERGICI 80
ACIDI (E)-a-[(1H-INDOL-3-IL)METILENE]BENZENEACETICI: UNA NUOVA CLASSE DI LIGANDI PER I RECETTORI DELLE ENDOTELINE 79
Heterocyclic systems containing the pyrimido-2,4-dione ring as selective ligands for the alpha1-adrenoceptors 79
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 79
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 78
Sintesi di 1,2,4 Triazoli come Ligandi per i Recettori delle Endoteline 78
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 78
Design and synthesis of novel potential ligands for endothelin receptors 77
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 77
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 75
Synthesis and pharmacological activity of 6H-thiazolo[3’,2’:1,2]-5-oxopyrimido[5,4-b] Indole derivatives, a new heterocyclic ring system 75
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as novel ligands for the 5-HT7 receptor 74
Pyrazolothiazolopyrimidine derivatives as novel class of anti-inflammatory or antinociceptive agents: synthesis, structural characterization and pharmacological evaluation 73
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinoline carboxylic acid derivatives 73
Totale 11.373
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Categoria #
all - tutte 55.406
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 55.406
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021464 0 0 0 0 0 22 114 5 82 11 162 68
2021/20221.547 185 210 60 28 227 27 221 63 142 20 42 322
2022/20232.485 225 127 59 261 254 438 3 410 557 27 102 22
2023/20241.006 58 171 48 55 86 221 6 58 4 36 149 114
2024/20254.022 33 606 244 247 740 381 315 221 364 340 271 260
2025/20265.247 480 224 1.538 377 1.187 1.441 0 0 0 0 0 0
Totale 17.065