IRIS
ROMEO, Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 7.489
EU - Europa 3.300
AS - Asia 2.952
SA - Sud America 609
AF - Africa 374
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 3
Totale 14.732
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Nazione #
US - Stati Uniti d'America 7.225
SG - Singapore 1.534
CN - Cina 972
IT - Italia 925
IE - Irlanda 690
BR - Brasile 552
UA - Ucraina 551
DE - Germania 354
CI - Costa d'Avorio 272
CA - Canada 236
RU - Federazione Russa 200
FI - Finlandia 175
VN - Vietnam 135
GB - Regno Unito 93
SE - Svezia 79
IN - India 71
FR - Francia 52
SN - Senegal 48
PL - Polonia 38
KR - Corea 37
JP - Giappone 33
ES - Italia 24
UZ - Uzbekistan 24
CH - Svizzera 23
IQ - Iraq 23
BD - Bangladesh 22
ZA - Sudafrica 22
NL - Olanda 21
TR - Turchia 21
AR - Argentina 20
MX - Messico 18
AT - Austria 16
IR - Iran 14
CZ - Repubblica Ceca 13
EC - Ecuador 13
HK - Hong Kong 13
ID - Indonesia 12
MA - Marocco 11
VE - Venezuela 11
GR - Grecia 10
BG - Bulgaria 8
LT - Lituania 7
EG - Egitto 6
PK - Pakistan 5
RO - Romania 5
TN - Tunisia 5
AE - Emirati Arabi Uniti 4
EU - Europa 4
IL - Israele 4
JO - Giordania 4
KE - Kenya 4
LU - Lussemburgo 4
OM - Oman 4
PY - Paraguay 4
AU - Australia 3
CL - Cile 3
CO - Colombia 3
DO - Repubblica Dominicana 3
LB - Libano 3
NG - Nigeria 3
NP - Nepal 3
AL - Albania 2
BE - Belgio 2
BY - Bielorussia 2
KZ - Kazakistan 2
LV - Lettonia 2
PH - Filippine 2
SA - Arabia Saudita 2
TT - Trinidad e Tobago 2
AZ - Azerbaigian 1
BH - Bahrain 1
BJ - Benin 1
DZ - Algeria 1
ET - Etiopia 1
GT - Guatemala 1
GY - Guiana 1
HN - Honduras 1
HU - Ungheria 1
JM - Giamaica 1
KG - Kirghizistan 1
KW - Kuwait 1
MD - Moldavia 1
MT - Malta 1
MY - Malesia 1
PA - Panama 1
PE - Perù 1
PS - Palestinian Territory 1
RS - Serbia 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
TW - Taiwan 1
UY - Uruguay 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 14.732
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Città #
Dallas 1.419
Chandler 904
Singapore 701
Dublin 688
Santa Clara 663
Jacksonville 588
Chicago 343
Ashburn 329
Boardman 309
Munich 289
Abidjan 272
Catania 250
Nanjing 202
Cambridge 191
Andover 190
Lawrence 190
Toronto 175
Beijing 153
Helsinki 133
Civitanova Marche 130
Houston 118
San Mateo 113
Wilmington 95
Des Moines 86
Los Angeles 84
Hefei 80
Nanchang 67
Shenyang 58
São Paulo 56
Dakar 48
Hebei 46
Saint Petersburg 42
Tianjin 42
Jiaxing 40
The Dalles 39
Changsha 38
Columbus 38
Dong Ket 37
Council Bluffs 36
Rome 36
Seoul 36
Ottawa 35
New York 34
Ho Chi Minh City 33
Florence 32
Tokyo 32
Hanoi 28
Naples 28
Bremen 26
Buffalo 26
Brooklyn 25
Redmond 24
Turku 21
Moscow 20
Belo Horizonte 19
Palermo 19
Phoenix 19
Washington 19
Mumbai 18
Pune 17
Seattle 17
Boydton 16
Warsaw 16
Augusta 15
Johannesburg 15
Falls Church 13
Jinan 13
Norwalk 13
Ardabil 12
Ningbo 12
Redondo Beach 12
Rio de Janeiro 12
Tashkent 12
Ann Arbor 11
Atlanta 11
Baghdad 11
Brasília 11
Curitiba 11
Hong Kong 11
Jakarta 11
Jyväskylä 11
Kunming 11
London 11
Messina 11
Milan 11
Montreal 11
Leawood 10
Manchester 10
Amsterdam 9
Chennai 9
Civitavecchia 9
Orem 9
Porto Alegre 9
San Francisco 9
Boston 8
Den Haag 8
Guarulhos 8
Liberty Lake 8
Osio Sotto 8
Pozzallo 8
Totale 10.272
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Nome #
(E)-alpha-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 269
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 250
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 249
[1,2,4]Triazole derivatives as 5-HT1A serotonin receptor ligands 190
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 155
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 148
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 145
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 140
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 139
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 137
A focus on Heme Oxygenase-1 (HO-1) inhibitors 124
(E)-alfa-[[(5-Substituted)1H-indol- 3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 123
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 123
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 118
3-ARILPIPERAZINILALCHILPIRROLO[3,2-d]PIRIMIDIN-2,4-DIONE: UNA NUOVA CLASSE DI LIGANDI POTENTI ED ALTAMENTE SELETTIVI PER I RECETTORI a 1-ADRENERGICI 117
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 113
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 112
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 112
Synthesis and binding properties of novel selective 5-HT3 receptor ligands 110
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 110
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 109
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 109
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 109
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective a1-adrenoceptor ligands 108
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 107
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 106
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 106
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 105
5-HT7 receptor ligands: recent developments and potential therapeutic applications 104
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 104
An alpha1-adrenergic receptor ligand repurposed as a potent antiproliferative agent for head and neck squamous cell carcinoma 102
Synthesis of novel 4,5-diphenylthiazole derivatives as potential acylCoA:cholesterol O-acyltransferase inhibitors 101
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 101
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 101
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 100
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 100
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 100
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 99
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 99
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 99
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 97
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 97
In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles 96
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 96
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 95
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 94
[Synthesis and antifungal activity of new derivatives of 5-(4-halobenzoyl)-4-amino-3-(2-dialkylaminoethylthio)thieno [2,3-c] and [3,2-d] isothiazole]. 93
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 93
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 92
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 91
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 91
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 90
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 90
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 89
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 88
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 88
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 87
[11C]RN5: A new agent for the in vivo imaging of myocardial alpha1-adrenoceptors 87
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 87
Pyrimido[5,4-b] Indole derivatives. 1. A new class of potent and selective alpha-1 adrenoceptor ligands 86
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 86
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 85
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 85
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 85
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 84
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 83
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 83
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 82
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 82
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 82
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 81
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 81
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 81
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 81
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 81
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 80
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 79
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases 79
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 78
Development of [methoxy-11C]RN5 as a potential radioligand for the in vivo PET measurement of myocardial alpha1A-adrenoceptors 76
Synthesis of new thieno[2,3-d]pyrimidine-(1H,3H)2,4-diones with analgesic and antiinflammatory activities 76
Synthesis and Binding Properties of New Endothelin Receptor Ligands 76
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 75
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinolinecarboxylic acid derivatives 74
ACIDI (E)-a-[(1H-INDOL-3-IL)METILENE]BENZENEACETICI: UNA NUOVA CLASSE DI LIGANDI PER I RECETTORI DELLE ENDOTELINE 74
Synthesis and endothelin receptor binding affinity of a novel class of (E)-α-[[(5-phenylmethoxy)-1H-indol-3-yl]methylene]benzeneacetic acids 74
SINTESI DI LIGANDI SELETTIVI PER I RECETTORI alfa1-ADRENERGICI 74
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 74
Heterocyclic systems containing the pyrimido-2,4-dione ring as selective ligands for the alpha1-adrenoceptors 73
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 73
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 73
[11C]RN5: un nuovo radiotracciante PET per l’imaging in vivo dei recettori alfa1-adrenergici miocardici 73
Curcumin I-SMA nanomicelles as promising therapeutic tool to tackle bacterial infections 72
Sintesi di 1,2,4 Triazoli come Ligandi per i Recettori delle Endoteline 71
Design and synthesis of novel potential ligands for endothelin receptors 70
Synthesis and pharmacological activity of 6H-thiazolo[3’,2’:1,2]-5-oxopyrimido[5,4-b] Indole derivatives, a new heterocyclic ring system 70
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as novel ligands for the 5-HT7 receptor 69
Pyrazolothiazolopyrimidine derivatives as novel class of anti-inflammatory or antinociceptive agents: synthesis, structural characterization and pharmacological evaluation 68
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinoline carboxylic acid derivatives 68
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 68
Totale 9.959
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Categoria #
all - tutte 51.985
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 51.985
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021770 0 0 0 0 306 22 114 5 82 11 162 68
2021/20221.547 185 210 60 28 227 27 221 63 142 20 42 322
2022/20232.485 225 127 59 261 254 438 3 410 557 27 102 22
2023/20241.006 58 171 48 55 86 221 6 58 4 36 149 114
2024/20254.022 33 606 244 247 740 381 315 221 364 340 271 260
2025/20263.298 480 224 1.538 377 679 0 0 0 0 0 0 0
Totale 15.116