IRIS
ROMEO, Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 9.233
EU - Europa 4.882
AS - Asia 4.111
SA - Sud America 745
AF - Africa 520
Continente sconosciuto - Info sul continente non disponibili 394
OC - Oceania 5
Totale 19.890
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Nazione #
US - Stati Uniti d'America 8.850
SG - Singapore 2.186
RU - Federazione Russa 1.322
CN - Cina 1.063
IT - Italia 1.026
IE - Irlanda 676
BR - Brasile 620
UA - Ucraina 540
DE - Germania 372
VN - Vietnam 290
CA - Canada 285
CI - Costa d'Avorio 272
FR - Francia 265
FI - Finlandia 184
SE - Svezia 126
GB - Regno Unito 123
KR - Corea 108
IN - India 103
NG - Nigeria 91
BD - Bangladesh 61
PL - Polonia 52
SN - Senegal 49
HK - Hong Kong 45
MX - Messico 42
ES - Italia 39
ZA - Sudafrica 39
AR - Argentina 36
IQ - Iraq 36
JP - Giappone 36
UZ - Uzbekistan 32
NL - Olanda 30
TR - Turchia 28
KE - Kenya 25
CH - Svizzera 22
VE - Venezuela 22
EC - Ecuador 21
CO - Colombia 20
MA - Marocco 18
AT - Austria 17
ID - Indonesia 17
PK - Pakistan 16
IR - Iran 15
JM - Giamaica 15
CZ - Repubblica Ceca 14
GR - Grecia 13
LT - Lituania 11
EG - Egitto 9
JO - Giordania 9
AE - Emirati Arabi Uniti 8
BG - Bulgaria 8
TN - Tunisia 8
CL - Cile 7
CR - Costa Rica 7
OM - Oman 7
PY - Paraguay 7
RO - Romania 7
AL - Albania 6
PH - Filippine 6
TT - Trinidad e Tobago 6
AU - Australia 5
IL - Israele 5
LB - Libano 5
MY - Malesia 5
NP - Nepal 5
SA - Arabia Saudita 5
BO - Bolivia 4
DO - Repubblica Dominicana 4
EU - Europa 4
GT - Guatemala 4
LU - Lussemburgo 4
LV - Lettonia 4
PA - Panama 4
UY - Uruguay 4
BY - Bielorussia 3
DZ - Algeria 3
ET - Etiopia 3
HN - Honduras 3
HU - Ungheria 3
PE - Perù 3
RS - Serbia 3
SV - El Salvador 3
XK - ???statistics.table.value.countryCode.XK??? 3
AZ - Azerbaigian 2
BE - Belgio 2
DK - Danimarca 2
DM - Dominica 2
GA - Gabon 2
KW - Kuwait 2
KZ - Kazakistan 2
MD - Moldavia 2
MT - Malta 2
NI - Nicaragua 2
PR - Porto Rico 2
PS - Palestinian Territory 2
SK - Slovacchia (Repubblica Slovacca) 2
SY - Repubblica araba siriana 2
BH - Bahrain 1
BJ - Benin 1
BS - Bahamas 1
BT - Bhutan 1
Totale 19.489
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Città #
Dallas 1.423
Singapore 1.252
Chandler 893
Santa Clara 711
San Jose 698
Dublin 674
Jacksonville 575
Moscow 538
Ashburn 521
Chicago 355
Boardman 300
Munich 289
Abidjan 272
Catania 261
Nanjing 196
Andover 189
Cambridge 188
Lawrence 187
Toronto 185
Lauterbourg 169
Beijing 167
Council Bluffs 157
Helsinki 141
Civitanova Marche 127
Los Angeles 124
San Mateo 109
Seoul 107
Houston 101
Wilmington 92
Des Moines 87
Ho Chi Minh City 84
New York 79
Hefei 78
São Paulo 72
Nanchang 67
Hanoi 58
Shenyang 58
Rome 50
Dakar 49
Buffalo 47
Hebei 45
Lagos 44
Florence 42
Tianjin 42
Saint Petersburg 41
Orem 40
Changsha 39
Columbus 39
Jiaxing 39
The Dalles 38
Dong Ket 37
Hong Kong 37
Ottawa 37
Abuja 36
Tokyo 35
Brooklyn 34
Phoenix 34
Naples 32
Warsaw 30
Johannesburg 29
Bremen 26
Atlanta 25
Redmond 24
Seattle 24
Belo Horizonte 23
Palermo 23
Montreal 22
Mumbai 22
Milan 21
Turku 21
Tashkent 19
Washington 19
Baghdad 18
Boydton 18
Denver 17
Pune 17
Rio de Janeiro 17
Amsterdam 16
Augusta 16
Dhaka 16
Manchester 16
London 15
San Francisco 15
Da Nang 14
Poplar 14
Boston 13
Brasília 13
Chennai 13
Curitiba 13
Falls Church 13
Frankfurt am Main 13
Jinan 13
Mexico City 13
Norwalk 13
Ardabil 12
Jakarta 12
Redondo Beach 12
Stockholm 12
Ann Arbor 11
Jyväskylä 11
Totale 13.145
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Nome #
(E)-alpha-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 319
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 301
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 298
[1,2,4]Triazole derivatives as 5-HT1A serotonin receptor ligands 235
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 204
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 197
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 196
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 194
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 188
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 184
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 182
(E)-alfa-[[(5-Substituted)1H-indol- 3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 171
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 171
A focus on Heme Oxygenase-1 (HO-1) inhibitors 168
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 166
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 162
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 161
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 160
3-ARILPIPERAZINILALCHILPIRROLO[3,2-d]PIRIMIDIN-2,4-DIONE: UNA NUOVA CLASSE DI LIGANDI POTENTI ED ALTAMENTE SELETTIVI PER I RECETTORI a 1-ADRENERGICI 159
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 158
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 152
5-HT7 receptor ligands: recent developments and potential therapeutic applications 152
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 151
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 149
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 147
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 147
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective a1-adrenoceptor ligands 145
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 144
[Synthesis and antifungal activity of new derivatives of 5-(4-halobenzoyl)-4-amino-3-(2-dialkylaminoethylthio)thieno [2,3-c] and [3,2-d] isothiazole]. 143
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 141
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 140
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 139
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 139
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 139
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 139
An alpha1-adrenergic receptor ligand repurposed as a potent antiproliferative agent for head and neck squamous cell carcinoma 137
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 136
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 134
In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles 132
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 132
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 131
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 129
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 129
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 129
Synthesis and binding properties of novel selective 5-HT3 receptor ligands 127
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 127
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 127
[11C]RN5: A new agent for the in vivo imaging of myocardial alpha1-adrenoceptors 127
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 126
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 126
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 123
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 123
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 122
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 121
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 120
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 120
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 120
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 119
Synthesis of novel 4,5-diphenylthiazole derivatives as potential acylCoA:cholesterol O-acyltransferase inhibitors 118
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 118
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 118
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 118
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 117
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 115
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 114
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 113
Curcumin I-SMA nanomicelles as promising therapeutic tool to tackle bacterial infections 111
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 111
Synthesis and Binding Properties of New Endothelin Receptor Ligands 111
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 110
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 110
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 109
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 106
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 106
[11C]RN5: un nuovo radiotracciante PET per l’imaging in vivo dei recettori alfa1-adrenergici miocardici 105
Pyrimido[5,4-b] Indole derivatives. 1. A new class of potent and selective alpha-1 adrenoceptor ligands 104
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 104
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinolinecarboxylic acid derivatives 101
Design and synthesis of novel potential ligands for endothelin receptors 100
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 100
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 99
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases 97
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 97
Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for alpha1-adrenoceptor subtypes. 96
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 96
ACIDI (E)-a-[(1H-INDOL-3-IL)METILENE]BENZENEACETICI: UNA NUOVA CLASSE DI LIGANDI PER I RECETTORI DELLE ENDOTELINE 95
Synthesis and endothelin receptor binding affinity of a novel class of (E)-α-[[(5-phenylmethoxy)-1H-indol-3-yl]methylene]benzeneacetic acids 95
Heterocyclic systems containing the pyrimido-2,4-dione ring as selective ligands for the alpha1-adrenoceptors 95
Synthesis of new thieno[2,3-d]pyrimidine-(1H,3H)2,4-diones with analgesic and antiinflammatory activities 94
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 94
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 94
Development of [methoxy-11C]RN5 as a potential radioligand for the in vivo PET measurement of myocardial alpha1A-adrenoceptors 93
Sintesi di 1,2,4 Triazoli come Ligandi per i Recettori delle Endoteline 92
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinoline carboxylic acid derivatives 92
SINTESI DI LIGANDI SELETTIVI PER I RECETTORI alfa1-ADRENERGICI 92
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as novel ligands for the 5-HT7 receptor 92
Synthesis and pharmacological activity of 6H-thiazolo[3’,2’:1,2]-5-oxopyrimido[5,4-b] Indole derivatives, a new heterocyclic ring system 91
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 90
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 89
Design and Synthesis of Novel Potential Ligands for Endothelin Receptors 87
Totale 13.347
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Categoria #
all - tutte 67.159
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 67.159
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.136 0 0 60 28 222 27 220 61 139 20 41 318
2022/20232.449 222 127 59 258 247 432 3 402 550 26 101 22
2023/2024995 57 169 46 53 86 221 6 58 4 36 147 112
2024/20253.965 33 597 240 244 728 375 315 218 360 334 266 255
2025/20267.618 475 222 1.518 376 1.170 1.471 951 156 420 461 229 169
2026/2027653 231 354 68 0 0 0 0 0 0 0 0 0
Totale 19.890