IRIS
ROMEO, Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 5.604
EU - Europa 3.209
AS - Asia 2.071
SA - Sud America 475
AF - Africa 266
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 3
Totale 11.632
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Nazione #
US - Stati Uniti d'America 5.369
SG - Singapore 1.112
IT - Italia 911
CN - Cina 705
IE - Irlanda 689
UA - Ucraina 549
BR - Brasile 444
DE - Germania 352
CA - Canada 222
RU - Federazione Russa 197
CI - Costa d'Avorio 184
FI - Finlandia 174
SE - Svezia 75
GB - Regno Unito 70
VN - Vietnam 56
IN - India 55
SN - Senegal 48
FR - Francia 47
PL - Polonia 26
CH - Svizzera 23
UZ - Uzbekistan 23
BD - Bangladesh 19
AT - Austria 16
ES - Italia 16
NL - Olanda 16
TR - Turchia 16
IQ - Iraq 15
CZ - Repubblica Ceca 13
IR - Iran 12
KR - Corea 12
ZA - Sudafrica 12
GR - Grecia 10
VE - Venezuela 10
AR - Argentina 8
BG - Bulgaria 8
JP - Giappone 8
MA - Marocco 8
EC - Ecuador 6
MX - Messico 6
PK - Pakistan 5
RO - Romania 5
TN - Tunisia 5
EU - Europa 4
LU - Lussemburgo 4
OM - Oman 4
AE - Emirati Arabi Uniti 3
AU - Australia 3
HK - Hong Kong 3
IL - Israele 3
JO - Giordania 3
KE - Kenya 3
LB - Libano 3
NG - Nigeria 3
BE - Belgio 2
CL - Cile 2
DO - Repubblica Dominicana 2
EG - Egitto 2
KZ - Kazakistan 2
NP - Nepal 2
PH - Filippine 2
PY - Paraguay 2
SA - Arabia Saudita 2
TT - Trinidad e Tobago 2
AZ - Azerbaigian 1
BY - Bielorussia 1
CO - Colombia 1
DZ - Algeria 1
GY - Guiana 1
HN - Honduras 1
HU - Ungheria 1
JM - Giamaica 1
KG - Kirghizistan 1
KW - Kuwait 1
LT - Lituania 1
LV - Lettonia 1
MD - Moldavia 1
MT - Malta 1
PE - Perù 1
PS - Palestinian Territory 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
TW - Taiwan 1
Totale 11.632
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Città #
Chandler 904
Dublin 687
Singapore 646
Santa Clara 644
Jacksonville 588
Chicago 337
Boardman 309
Munich 289
Catania 241
Ashburn 202
Nanjing 202
Cambridge 191
Andover 190
Lawrence 190
Abidjan 184
Toronto 172
Helsinki 133
Civitanova Marche 130
San Mateo 113
Houston 112
Wilmington 95
Des Moines 86
Nanchang 67
Shenyang 58
Dakar 48
Hebei 46
Saint Petersburg 42
Tianjin 42
Jiaxing 40
São Paulo 40
The Dalles 39
Changsha 38
Columbus 38
Dong Ket 37
Ottawa 35
Rome 35
Council Bluffs 34
Florence 32
Beijing 29
Naples 28
Bremen 26
Los Angeles 25
Hefei 24
Redmond 24
Turku 21
Moscow 20
Palermo 19
Washington 19
Belo Horizonte 18
Pune 17
Boydton 16
Augusta 15
Mumbai 14
New York 14
Falls Church 13
Jinan 13
Norwalk 13
Seattle 13
Ardabil 12
Brooklyn 12
Ningbo 12
Phoenix 12
Ann Arbor 11
Jyväskylä 11
Kunming 11
Messina 11
Seoul 11
Tashkent 11
Leawood 10
Rio de Janeiro 10
Civitavecchia 9
Hanoi 9
Den Haag 8
Johannesburg 8
Liberty Lake 8
London 8
Milan 8
Osio Sotto 8
Pozzallo 8
San Francisco 8
Barcelona 7
Brasília 7
Brno 7
Centro 7
Dallas 7
Dhaka 7
Guarulhos 7
Padova 7
Siracusa 7
Tokyo 7
Zhengzhou 7
Baghdad 6
Ferrara di Monte Baldo 6
Guangzhou 6
Hangzhou 6
Porto Alegre 6
Redwood City 6
Ribeirão Preto 6
Salerno 6
Turin 6
Totale 8.044
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Nome #
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 218
(E)-alpha-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 216
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 210
[1,2,4]Triazole derivatives as 5-HT1A serotonin receptor ligands 150
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 135
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 130
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 124
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 110
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 107
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 107
A focus on Heme Oxygenase-1 (HO-1) inhibitors 101
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 97
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 94
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 94
An alpha1-adrenergic receptor ligand repurposed as a potent antiproliferative agent for head and neck squamous cell carcinoma 92
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 91
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 90
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 87
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 87
Synthesis and binding properties of novel selective 5-HT3 receptor ligands 86
3-ARILPIPERAZINILALCHILPIRROLO[3,2-d]PIRIMIDIN-2,4-DIONE: UNA NUOVA CLASSE DI LIGANDI POTENTI ED ALTAMENTE SELETTIVI PER I RECETTORI a 1-ADRENERGICI 86
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 86
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 85
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 85
Synthesis of novel 4,5-diphenylthiazole derivatives as potential acylCoA:cholesterol O-acyltransferase inhibitors 83
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 83
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 83
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 82
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 81
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 79
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 79
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 78
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 78
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 77
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 76
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 76
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 76
5-HT7 receptor ligands: recent developments and potential therapeutic applications 75
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 75
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 75
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 75
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 74
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 74
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 73
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective a1-adrenoceptor ligands 73
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 73
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 72
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 72
In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles 72
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 72
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 70
Development of [methoxy-11C]RN5 as a potential radioligand for the in vivo PET measurement of myocardial alpha1A-adrenoceptors 70
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 70
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 70
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 70
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 69
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases 69
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 69
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 69
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 68
ACIDI (E)-a-[(1H-INDOL-3-IL)METILENE]BENZENEACETICI: UNA NUOVA CLASSE DI LIGANDI PER I RECETTORI DELLE ENDOTELINE 67
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 67
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 67
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 66
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 66
[Synthesis and antifungal activity of new derivatives of 5-(4-halobenzoyl)-4-amino-3-(2-dialkylaminoethylthio)thieno [2,3-c] and [3,2-d] isothiazole]. 66
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 66
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 66
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 65
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 64
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 63
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 63
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 63
(E)-alfa-[[(5-Substituted)1H-indol- 3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 63
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 62
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 62
Synthesis of new thieno[2,3-d]pyrimidine-(1H,3H)2,4-diones with analgesic and antiinflammatory activities 62
Sintesi di 1,2,4 Triazoli come Ligandi per i Recettori delle Endoteline 62
SINTESI DI LIGANDI SELETTIVI PER I RECETTORI alfa1-ADRENERGICI 62
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 62
Synthesis and Binding Properties of New Endothelin Receptor Ligands 62
Heterocyclic systems containing the pyrimido-2,4-dione ring as selective ligands for the alpha1-adrenoceptors 61
Design and synthesis of novel potential ligands for endothelin receptors 61
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 61
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 61
[11C]RN5: A new agent for the in vivo imaging of myocardial alpha1-adrenoceptors 61
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 61
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 60
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 60
Arylpiperazinylalkylthio benzothiazole or benzoxazole derivatives as selective 5-HT1A serotonin receptor ligands 59
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 58
Synthesis and pharmacological activity of 6H-thiazolo[3’,2’:1,2]-5-oxopyrimido[5,4-b] Indole derivatives, a new heterocyclic ring system 58
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 57
Benzothieno[3,2-d]pyrimidine ligands with high affinity for human α1-adrenergic receptor subtypes 57
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as novel ligands for the 5-HT7 receptor 57
Pyrazolothiazolopyrimidine derivatives as novel class of anti-inflammatory or antinociceptive agents: synthesis, structural characterization and pharmacological evaluation 56
Pyrimido[5,4-b] Indole derivatives. 1. A new class of potent and selective alpha-1 adrenoceptor ligands 56
Synthesis and endothelin receptor binding affinity of a novel class of (E)-α-[[(5-phenylmethoxy)-1H-indol-3-yl]methylene]benzeneacetic acids 56
Synthesis and pharmacological evaluation of pyrazolopyrimidobenzoxazole and pyrazolopyrimidobenzothiazole derivatives 56
PROGRESS IN THE DEVELOPMENT OF SELECTIVE NITRIC OXIDE SYNTHASE (NOS) INHIBITORS 55
Totale 7.905
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Categoria #
all - tutte 43.296
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 43.296
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.036 7 102 132 25 306 22 114 5 82 11 162 68
2021/20221.547 185 210 60 28 227 27 221 63 142 20 42 322
2022/20232.485 225 127 59 261 254 438 3 410 557 27 102 22
2023/20241.006 58 171 48 55 86 221 6 58 4 36 149 114
2024/20254.022 33 606 244 247 740 381 315 221 364 340 271 260
2025/2026198 198 0 0 0 0 0 0 0 0 0 0 0
Totale 12.016