IRIS
ROMEO, Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 5.339
EU - Europa 3.107
AS - Asia 1.861
SA - Sud America 257
AF - Africa 251
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 3
Totale 10.822
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Nazione #
US - Stati Uniti d'America 5.125
SG - Singapore 1.029
IT - Italia 896
IE - Irlanda 688
CN - Cina 663
UA - Ucraina 546
DE - Germania 332
BR - Brasile 239
CA - Canada 208
RU - Federazione Russa 189
CI - Costa d'Avorio 184
FI - Finlandia 153
SE - Svezia 74
GB - Regno Unito 51
SN - Senegal 48
FR - Francia 45
VN - Vietnam 44
IN - India 37
CH - Svizzera 23
UZ - Uzbekistan 23
PL - Polonia 21
AT - Austria 15
NL - Olanda 15
ES - Italia 14
IR - Iran 12
CZ - Repubblica Ceca 11
TR - Turchia 11
GR - Grecia 10
BG - Bulgaria 8
IQ - Iraq 7
AR - Argentina 6
BD - Bangladesh 6
JP - Giappone 6
MA - Marocco 6
EC - Ecuador 5
RO - Romania 5
EU - Europa 4
LU - Lussemburgo 4
MX - Messico 4
PK - Pakistan 4
TN - Tunisia 4
VE - Venezuela 4
AU - Australia 3
OM - Oman 3
ZA - Sudafrica 3
BE - Belgio 2
CL - Cile 2
EG - Egitto 2
HK - Hong Kong 2
IL - Israele 2
LB - Libano 2
NG - Nigeria 2
PH - Filippine 2
AE - Emirati Arabi Uniti 1
BY - Bielorussia 1
CO - Colombia 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
HU - Ungheria 1
KE - Kenya 1
KG - Kirghizistan 1
KR - Corea 1
KZ - Kazakistan 1
LV - Lettonia 1
MD - Moldavia 1
MT - Malta 1
NP - Nepal 1
PS - Palestinian Territory 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
TW - Taiwan 1
Totale 10.822
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Città #
Chandler 904
Dublin 687
Santa Clara 641
Jacksonville 588
Singapore 563
Chicago 329
Boardman 309
Munich 271
Catania 239
Nanjing 202
Ashburn 196
Cambridge 191
Andover 190
Lawrence 190
Abidjan 184
Toronto 171
Helsinki 133
Civitanova Marche 130
San Mateo 113
Houston 111
Wilmington 95
Des Moines 86
Nanchang 67
Shenyang 58
Dakar 48
Hebei 46
Saint Petersburg 42
Tianjin 42
Jiaxing 40
Changsha 38
Dong Ket 37
Ottawa 35
Council Bluffs 34
Florence 32
Naples 28
Bremen 26
São Paulo 26
Redmond 24
Rome 23
Moscow 20
Palermo 18
Washington 18
Los Angeles 17
Boydton 16
Pune 16
Augusta 15
Falls Church 13
Jinan 13
Norwalk 13
Ardabil 12
Ningbo 12
Seattle 12
Ann Arbor 11
Beijing 11
Jyväskylä 11
Kunming 11
Messina 11
Tashkent 11
Leawood 10
Civitavecchia 9
Mumbai 9
Belo Horizonte 8
Den Haag 8
Liberty Lake 8
Milan 8
Osio Sotto 8
Phoenix 8
Pozzallo 8
Barcelona 7
Brno 7
Centro 7
Hanoi 7
Padova 7
Siracusa 7
Zhengzhou 7
Ferrara di Monte Baldo 6
Guangzhou 6
Hangzhou 6
Redwood City 6
Salerno 6
Turin 6
Edinburgh 5
Fairfield 5
Gela 5
Guarulhos 5
Latina 5
Madrid 5
Reggio Calabria 5
Shanghai 5
The Dalles 5
Tokyo 5
Aci Catena 4
Amsterdam 4
Castelvetrano 4
Cergy 4
Contagem 4
Frankfurt Am Main 4
Garbagnate Milanese 4
Istanbul 4
Lanzhou 4
Totale 7.685
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Nome #
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 212
(E)-alpha-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 210
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 200
[1,2,4]Triazole derivatives as 5-HT1A serotonin receptor ligands 141
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 131
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 127
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 114
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 104
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 99
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 97
A focus on Heme Oxygenase-1 (HO-1) inhibitors 94
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 91
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 90
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 89
An alpha1-adrenergic receptor ligand repurposed as a potent antiproliferative agent for head and neck squamous cell carcinoma 88
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 84
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 84
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 83
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 81
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 81
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 81
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 80
Synthesis and binding properties of novel selective 5-HT3 receptor ligands 79
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 79
3-ARILPIPERAZINILALCHILPIRROLO[3,2-d]PIRIMIDIN-2,4-DIONE: UNA NUOVA CLASSE DI LIGANDI POTENTI ED ALTAMENTE SELETTIVI PER I RECETTORI a 1-ADRENERGICI 78
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 77
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 77
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 77
Synthesis of novel 4,5-diphenylthiazole derivatives as potential acylCoA:cholesterol O-acyltransferase inhibitors 76
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 76
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 75
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 75
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 73
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 72
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 72
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 71
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 70
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 70
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 69
5-HT7 receptor ligands: recent developments and potential therapeutic applications 69
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 69
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 68
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective a1-adrenoceptor ligands 68
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 68
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 68
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 68
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 68
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 67
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 67
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 67
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 67
Development of [methoxy-11C]RN5 as a potential radioligand for the in vivo PET measurement of myocardial alpha1A-adrenoceptors 65
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases 65
In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles 65
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 65
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 65
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 64
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 64
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 64
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 62
ACIDI (E)-a-[(1H-INDOL-3-IL)METILENE]BENZENEACETICI: UNA NUOVA CLASSE DI LIGANDI PER I RECETTORI DELLE ENDOTELINE 62
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 62
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 62
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 61
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 61
[Synthesis and antifungal activity of new derivatives of 5-(4-halobenzoyl)-4-amino-3-(2-dialkylaminoethylthio)thieno [2,3-c] and [3,2-d] isothiazole]. 61
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 61
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 61
Design and synthesis of novel potential ligands for endothelin receptors 60
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 60
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 60
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 59
Sintesi di 1,2,4 Triazoli come Ligandi per i Recettori delle Endoteline 59
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 59
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 59
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 58
Arylpiperazinylalkylthio benzothiazole or benzoxazole derivatives as selective 5-HT1A serotonin receptor ligands 58
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 58
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 58
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 58
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 58
SINTESI DI LIGANDI SELETTIVI PER I RECETTORI alfa1-ADRENERGICI 57
(E)-alfa-[[(5-Substituted)1H-indol- 3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 57
[11C]RN5: A new agent for the in vivo imaging of myocardial alpha1-adrenoceptors 57
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 57
Benzothieno[3,2-d]pyrimidine ligands with high affinity for human α1-adrenergic receptor subtypes 56
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 56
Synthesis and Binding Properties of New Endothelin Receptor Ligands 56
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 56
Synthesis of new thieno[2,3-d]pyrimidine-(1H,3H)2,4-diones with analgesic and antiinflammatory activities 55
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as novel ligands for the 5-HT7 receptor 55
Synthesis and pharmacological activity of 6H-thiazolo[3’,2’:1,2]-5-oxopyrimido[5,4-b] Indole derivatives, a new heterocyclic ring system 55
Pyrimido[5,4-b] Indole derivatives. 1. A new class of potent and selective alpha-1 adrenoceptor ligands 54
Heterocyclic systems containing the pyrimido-2,4-dione ring as selective ligands for the alpha1-adrenoceptors 54
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 54
Synthesis and endothelin receptor binding affinity of a novel class of (E)-α-[[(5-phenylmethoxy)-1H-indol-3-yl]methylene]benzeneacetic acids 53
Caffeic Acid Phenethyl Ester (CAPE) derivatives as novel heme oxygenase-1 inducers. 53
PROGRESS IN THE DEVELOPMENT OF SELECTIVE NITRIC OXIDE SYNTHASE (NOS) INHIBITORS 53
Pyrazolothiazolopyrimidine derivatives as novel class of anti-inflammatory or antinociceptive agents: synthesis, structural characterization and pharmacological evaluation 52
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinoline carboxylic acid derivatives 52
Totale 7.417
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Categoria #
all - tutte 39.273
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.273
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020202 0 0 0 0 0 0 0 0 0 44 117 41
2020/20211.036 7 102 132 25 306 22 114 5 82 11 162 68
2021/20221.547 185 210 60 28 227 27 221 63 142 20 42 322
2022/20232.485 225 127 59 261 254 438 3 410 557 27 102 22
2023/20241.006 58 171 48 55 86 221 6 58 4 36 149 114
2024/20253.410 33 606 244 247 740 381 315 221 364 259 0 0
Totale 11.206