IRIS
ROMEO, Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 8.856
EU - Europa 4.809
AS - Asia 4.082
SA - Sud America 740
AF - Africa 519
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 5
Totale 19.018
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Nazione #
US - Stati Uniti d'America 8.501
SG - Singapore 2.184
RU - Federazione Russa 1.322
CN - Cina 1.060
IT - Italia 993
IE - Irlanda 676
BR - Brasile 619
UA - Ucraina 540
DE - Germania 372
VN - Vietnam 285
CI - Costa d'Avorio 272
CA - Canada 270
FR - Francia 265
FI - Finlandia 184
GB - Regno Unito 122
KR - Corea 108
IN - India 103
NG - Nigeria 91
SE - Svezia 90
BD - Bangladesh 52
PL - Polonia 52
SN - Senegal 49
HK - Hong Kong 41
MX - Messico 41
ZA - Sudafrica 39
ES - Italia 38
AR - Argentina 36
IQ - Iraq 36
JP - Giappone 36
UZ - Uzbekistan 32
NL - Olanda 30
TR - Turchia 28
KE - Kenya 25
CH - Svizzera 22
VE - Venezuela 22
EC - Ecuador 20
CO - Colombia 18
MA - Marocco 18
AT - Austria 17
ID - Indonesia 17
IR - Iran 15
CZ - Repubblica Ceca 14
GR - Grecia 13
JM - Giamaica 12
PK - Pakistan 12
LT - Lituania 11
AE - Emirati Arabi Uniti 8
BG - Bulgaria 8
EG - Egitto 8
JO - Giordania 8
TN - Tunisia 8
CL - Cile 7
OM - Oman 7
PY - Paraguay 7
RO - Romania 7
AL - Albania 6
PH - Filippine 6
AU - Australia 5
CR - Costa Rica 5
IL - Israele 5
LB - Libano 5
MY - Malesia 5
NP - Nepal 5
SA - Arabia Saudita 5
BO - Bolivia 4
EU - Europa 4
GT - Guatemala 4
LU - Lussemburgo 4
LV - Lettonia 4
PA - Panama 4
TT - Trinidad e Tobago 4
UY - Uruguay 4
BY - Bielorussia 3
DO - Repubblica Dominicana 3
DZ - Algeria 3
ET - Etiopia 3
HN - Honduras 3
HU - Ungheria 3
RS - Serbia 3
XK - ???statistics.table.value.countryCode.XK??? 3
AZ - Azerbaigian 2
BE - Belgio 2
DK - Danimarca 2
DM - Dominica 2
GA - Gabon 2
KW - Kuwait 2
KZ - Kazakistan 2
MT - Malta 2
NI - Nicaragua 2
PE - Perù 2
PR - Porto Rico 2
PS - Palestinian Territory 2
SK - Slovacchia (Repubblica Slovacca) 2
SY - Repubblica araba siriana 2
BH - Bahrain 1
BJ - Benin 1
BS - Bahamas 1
BT - Bhutan 1
CY - Cipro 1
GY - Guiana 1
Totale 19.008
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Città #
Dallas 1.413
Singapore 1.250
Chandler 893
Santa Clara 689
San Jose 675
Dublin 674
Jacksonville 575
Moscow 538
Ashburn 514
Chicago 345
Boardman 300
Munich 289
Abidjan 272
Catania 259
Nanjing 196
Andover 189
Cambridge 188
Lawrence 187
Toronto 185
Lauterbourg 169
Beijing 164
Helsinki 141
Civitanova Marche 127
Los Angeles 116
San Mateo 109
Seoul 107
Houston 101
Wilmington 92
Des Moines 87
Ho Chi Minh City 83
Hefei 78
São Paulo 72
New York 71
Nanchang 67
Shenyang 58
Hanoi 57
Council Bluffs 49
Dakar 49
Rome 47
Buffalo 45
Hebei 45
Lagos 44
Tianjin 42
Florence 41
Saint Petersburg 41
Orem 40
Changsha 39
Jiaxing 39
Columbus 38
The Dalles 38
Dong Ket 37
Abuja 36
Ottawa 36
Tokyo 35
Hong Kong 33
Brooklyn 32
Phoenix 31
Warsaw 30
Johannesburg 29
Naples 29
Bremen 26
Atlanta 24
Redmond 24
Belo Horizonte 23
Palermo 23
Mumbai 22
Montreal 21
Turku 21
Tashkent 19
Washington 19
Baghdad 18
Boydton 18
Pune 17
Rio de Janeiro 17
Seattle 17
Amsterdam 16
Denver 16
Manchester 16
Milan 16
Augusta 15
London 15
Da Nang 14
Dhaka 14
Poplar 14
Chennai 13
Curitiba 13
Falls Church 13
Frankfurt am Main 13
Jinan 13
Mexico City 13
Norwalk 13
Ardabil 12
Brasília 12
Jakarta 12
Redondo Beach 12
San Francisco 12
Stockholm 12
Ann Arbor 11
Jyväskylä 11
Kunming 11
Totale 12.896
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Nome #
(E)-alpha-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 317
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 299
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 296
[1,2,4]Triazole derivatives as 5-HT1A serotonin receptor ligands 233
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 202
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 195
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 192
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 188
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 187
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 178
(E)-alfa-[[(5-Substituted)1H-indol- 3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 169
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 169
A focus on Heme Oxygenase-1 (HO-1) inhibitors 164
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 159
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 158
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 157
3-ARILPIPERAZINILALCHILPIRROLO[3,2-d]PIRIMIDIN-2,4-DIONE: UNA NUOVA CLASSE DI LIGANDI POTENTI ED ALTAMENTE SELETTIVI PER I RECETTORI a 1-ADRENERGICI 157
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 157
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 152
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 150
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 149
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 148
5-HT7 receptor ligands: recent developments and potential therapeutic applications 148
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 146
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective a1-adrenoceptor ligands 144
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 143
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 142
[Synthesis and antifungal activity of new derivatives of 5-(4-halobenzoyl)-4-amino-3-(2-dialkylaminoethylthio)thieno [2,3-c] and [3,2-d] isothiazole]. 140
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 139
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 139
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 137
An alpha1-adrenergic receptor ligand repurposed as a potent antiproliferative agent for head and neck squamous cell carcinoma 136
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 136
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 135
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 135
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 134
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 133
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 132
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 128
In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles 128
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 128
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 126
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 126
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 125
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 125
Synthesis and binding properties of novel selective 5-HT3 receptor ligands 124
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 123
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 122
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 122
[11C]RN5: A new agent for the in vivo imaging of myocardial alpha1-adrenoceptors 122
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 120
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 118
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 118
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 118
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 118
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 117
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 116
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 116
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 116
Synthesis of novel 4,5-diphenylthiazole derivatives as potential acylCoA:cholesterol O-acyltransferase inhibitors 115
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 115
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 114
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 112
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 111
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 111
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 111
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 108
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 108
Curcumin I-SMA nanomicelles as promising therapeutic tool to tackle bacterial infections 107
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 106
Synthesis and Binding Properties of New Endothelin Receptor Ligands 105
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 103
Pyrimido[5,4-b] Indole derivatives. 1. A new class of potent and selective alpha-1 adrenoceptor ligands 102
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 102
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 102
[11C]RN5: un nuovo radiotracciante PET per l’imaging in vivo dei recettori alfa1-adrenergici miocardici 102
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 101
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 99
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinolinecarboxylic acid derivatives 98
Design and synthesis of novel potential ligands for endothelin receptors 97
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 95
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases 95
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 95
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 95
Synthesis and endothelin receptor binding affinity of a novel class of (E)-α-[[(5-phenylmethoxy)-1H-indol-3-yl]methylene]benzeneacetic acids 94
Synthesis of new thieno[2,3-d]pyrimidine-(1H,3H)2,4-diones with analgesic and antiinflammatory activities 93
ACIDI (E)-a-[(1H-INDOL-3-IL)METILENE]BENZENEACETICI: UNA NUOVA CLASSE DI LIGANDI PER I RECETTORI DELLE ENDOTELINE 93
Heterocyclic systems containing the pyrimido-2,4-dione ring as selective ligands for the alpha1-adrenoceptors 93
Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for alpha1-adrenoceptor subtypes. 93
Sintesi di 1,2,4 Triazoli come Ligandi per i Recettori delle Endoteline 91
SINTESI DI LIGANDI SELETTIVI PER I RECETTORI alfa1-ADRENERGICI 91
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 91
Development of [methoxy-11C]RN5 as a potential radioligand for the in vivo PET measurement of myocardial alpha1A-adrenoceptors 89
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinoline carboxylic acid derivatives 89
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as novel ligands for the 5-HT7 receptor 89
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 89
Synthesis and pharmacological activity of 6H-thiazolo[3’,2’:1,2]-5-oxopyrimido[5,4-b] Indole derivatives, a new heterocyclic ring system 89
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 88
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 87
Design and Synthesis of Novel Potential Ligands for Endothelin Receptors 85
Totale 13.004
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Categoria #
all - tutte 63.319
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 63.319
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.525 182 207 60 28 222 27 220 61 139 20 41 318
2022/20232.449 222 127 59 258 247 432 3 402 550 26 101 22
2023/2024995 57 169 46 53 86 221 6 58 4 36 147 112
2024/20253.965 33 597 240 244 728 375 315 218 360 334 266 255
2025/20267.618 475 222 1.518 376 1.170 1.471 951 156 420 461 229 169
2026/2027168 168 0 0 0 0 0 0 0 0 0 0 0
Totale 19.405