IRIS
ROMEO, Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 7.575
EU - Europa 4.031
AS - Asia 3.381
SA - Sud America 615
AF - Africa 375
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 3
Totale 15.985
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Nazione #
US - Stati Uniti d'America 7.306
SG - Singapore 1.943
CN - Cina 984
IT - Italia 925
RU - Federazione Russa 911
IE - Irlanda 690
BR - Brasile 555
UA - Ucraina 551
DE - Germania 355
CI - Costa d'Avorio 272
CA - Canada 238
FI - Finlandia 175
VN - Vietnam 135
GB - Regno Unito 97
SE - Svezia 81
IN - India 74
FR - Francia 54
SN - Senegal 48
PL - Polonia 43
KR - Corea 37
JP - Giappone 34
ES - Italia 27
IQ - Iraq 24
NL - Olanda 24
UZ - Uzbekistan 24
BD - Bangladesh 23
CH - Svizzera 23
ZA - Sudafrica 23
AR - Argentina 22
MX - Messico 21
TR - Turchia 21
AT - Austria 16
HK - Hong Kong 15
IR - Iran 14
CZ - Repubblica Ceca 13
EC - Ecuador 13
ID - Indonesia 12
MA - Marocco 11
VE - Venezuela 11
GR - Grecia 10
BG - Bulgaria 8
LT - Lituania 7
EG - Egitto 6
PK - Pakistan 5
RO - Romania 5
TN - Tunisia 5
AE - Emirati Arabi Uniti 4
CL - Cile 4
EU - Europa 4
IL - Israele 4
JO - Giordania 4
KE - Kenya 4
LU - Lussemburgo 4
OM - Oman 4
PY - Paraguay 4
AU - Australia 3
CO - Colombia 3
DO - Repubblica Dominicana 3
LB - Libano 3
NG - Nigeria 3
NP - Nepal 3
AL - Albania 2
BE - Belgio 2
BY - Bielorussia 2
KZ - Kazakistan 2
LV - Lettonia 2
PH - Filippine 2
SA - Arabia Saudita 2
TT - Trinidad e Tobago 2
AZ - Azerbaigian 1
BH - Bahrain 1
BJ - Benin 1
DZ - Algeria 1
ET - Etiopia 1
GT - Guatemala 1
GY - Guiana 1
HN - Honduras 1
HU - Ungheria 1
JM - Giamaica 1
KG - Kirghizistan 1
KW - Kuwait 1
MD - Moldavia 1
MT - Malta 1
MY - Malesia 1
PA - Panama 1
PE - Perù 1
PS - Palestinian Territory 1
RS - Serbia 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
TW - Taiwan 1
UY - Uruguay 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 15.985
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Città #
Dallas 1.421
Singapore 1.070
Chandler 904
Dublin 688
Santa Clara 664
Jacksonville 588
Moscow 395
Ashburn 351
Chicago 343
Boardman 309
Munich 289
Abidjan 272
Catania 250
Nanjing 202
Cambridge 191
Andover 190
Lawrence 190
Toronto 176
Beijing 154
Helsinki 133
Civitanova Marche 130
Houston 118
San Mateo 113
Wilmington 95
Los Angeles 94
Des Moines 86
Hefei 80
Nanchang 67
Shenyang 58
São Paulo 56
Dakar 48
Hebei 46
Tianjin 43
New York 42
Saint Petersburg 42
Jiaxing 40
Changsha 39
The Dalles 39
Columbus 38
Dong Ket 37
Council Bluffs 36
Rome 36
Seoul 36
Buffalo 35
Ottawa 35
Ho Chi Minh City 33
Tokyo 33
Florence 32
Hanoi 28
Naples 28
Brooklyn 27
Bremen 26
Redmond 24
Turku 21
Warsaw 21
Belo Horizonte 19
Mumbai 19
Palermo 19
Phoenix 19
Washington 19
Pune 17
Seattle 17
Boydton 16
Johannesburg 16
Augusta 15
Orem 15
Atlanta 13
Falls Church 13
Hong Kong 13
Jinan 13
Norwalk 13
Ardabil 12
Baghdad 12
Montreal 12
Ningbo 12
Redondo Beach 12
Rio de Janeiro 12
Tashkent 12
Amsterdam 11
Ann Arbor 11
Brasília 11
Curitiba 11
Jakarta 11
Jyväskylä 11
Kunming 11
London 11
Messina 11
Milan 11
Chennai 10
Leawood 10
Manchester 10
Poplar 10
Civitavecchia 9
Porto Alegre 9
San Francisco 9
Boston 8
Den Haag 8
Guangzhou 8
Guarulhos 8
Liberty Lake 8
Totale 11.099
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Nome #
(E)-alpha-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 288
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 272
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 267
[1,2,4]Triazole derivatives as 5-HT1A serotonin receptor ligands 207
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 175
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 165
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 162
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 158
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 154
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 153
(E)-alfa-[[(5-Substituted)1H-indol- 3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 144
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 142
A focus on Heme Oxygenase-1 (HO-1) inhibitors 141
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 136
3-ARILPIPERAZINILALCHILPIRROLO[3,2-d]PIRIMIDIN-2,4-DIONE: UNA NUOVA CLASSE DI LIGANDI POTENTI ED ALTAMENTE SELETTIVI PER I RECETTORI a 1-ADRENERGICI 130
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 130
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 130
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 128
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 126
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 125
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 124
5-HT7 receptor ligands: recent developments and potential therapeutic applications 123
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective a1-adrenoceptor ligands 122
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 119
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 119
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 118
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 118
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 116
An alpha1-adrenergic receptor ligand repurposed as a potent antiproliferative agent for head and neck squamous cell carcinoma 116
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 116
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 115
Synthesis and binding properties of novel selective 5-HT3 receptor ligands 113
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 113
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 113
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 113
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 110
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 109
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 109
[Synthesis and antifungal activity of new derivatives of 5-(4-halobenzoyl)-4-amino-3-(2-dialkylaminoethylthio)thieno [2,3-c] and [3,2-d] isothiazole]. 108
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 108
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 108
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 108
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 108
In vitro antioxidant activity of idebenone derivative-loaded solid lipid nanoparticles 107
Synthesis of novel 4,5-diphenylthiazole derivatives as potential acylCoA:cholesterol O-acyltransferase inhibitors 105
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 105
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 105
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 104
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 104
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 104
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 102
[11C]RN5: A new agent for the in vivo imaging of myocardial alpha1-adrenoceptors 101
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 99
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 98
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 98
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 96
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 95
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 95
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 95
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 95
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 94
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 93
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 93
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 92
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 92
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 92
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 91
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 90
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 90
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 89
Pyrimido[5,4-b] Indole derivatives. 1. A new class of potent and selective alpha-1 adrenoceptor ligands 89
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 87
Curcumin I-SMA nanomicelles as promising therapeutic tool to tackle bacterial infections 86
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 86
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 85
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 84
[11C]RN5: un nuovo radiotracciante PET per l’imaging in vivo dei recettori alfa1-adrenergici miocardici 84
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 84
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinolinecarboxylic acid derivatives 83
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 83
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 81
Synthesis of new thiazinoindole derivatives and their evaluation as inhibitors of human leukocyte elastase and other related serine proteases 81
Synthesis and Binding Properties of New Endothelin Receptor Ligands 81
Development of [methoxy-11C]RN5 as a potential radioligand for the in vivo PET measurement of myocardial alpha1A-adrenoceptors 79
Synthesis of new thieno[2,3-d]pyrimidine-(1H,3H)2,4-diones with analgesic and antiinflammatory activities 78
Synthesis and endothelin receptor binding affinity of a novel class of (E)-α-[[(5-phenylmethoxy)-1H-indol-3-yl]methylene]benzeneacetic acids 78
ACIDI (E)-a-[(1H-INDOL-3-IL)METILENE]BENZENEACETICI: UNA NUOVA CLASSE DI LIGANDI PER I RECETTORI DELLE ENDOTELINE 77
SINTESI DI LIGANDI SELETTIVI PER I RECETTORI alfa1-ADRENERGICI 77
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 76
Heterocyclic systems containing the pyrimido-2,4-dione ring as selective ligands for the alpha1-adrenoceptors 76
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 76
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 75
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 75
Sintesi di 1,2,4 Triazoli come Ligandi per i Recettori delle Endoteline 74
Design and synthesis of novel potential ligands for endothelin receptors 74
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 72
Pyrazolothiazolopyrimidine derivatives as novel class of anti-inflammatory or antinociceptive agents: synthesis, structural characterization and pharmacological evaluation 71
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as novel ligands for the 5-HT7 receptor 71
Synthesis and pharmacological activity of 6H-thiazolo[3’,2’:1,2]-5-oxopyrimido[5,4-b] Indole derivatives, a new heterocyclic ring system 71
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinoline carboxylic acid derivatives 70
Totale 10.947
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Categoria #
all - tutte 53.821
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 53.821
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021464 0 0 0 0 0 22 114 5 82 11 162 68
2021/20221.547 185 210 60 28 227 27 221 63 142 20 42 322
2022/20232.485 225 127 59 261 254 438 3 410 557 27 102 22
2023/20241.006 58 171 48 55 86 221 6 58 4 36 149 114
2024/20254.022 33 606 244 247 740 381 315 221 364 340 271 260
2025/20264.551 480 224 1.538 377 1.187 745 0 0 0 0 0 0
Totale 16.369