IRIS
MANZELLA, LIVIA
 Distribuzione geografica
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Continente #
NA - Nord America 5.721
EU - Europa 3.398
AS - Asia 2.832
SA - Sud America 562
AF - Africa 437
Continente sconosciuto - Info sul continente non disponibili 225
OC - Oceania 8
Totale 13.183
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Nazione #
US - Stati Uniti d'America 5.511
SG - Singapore 1.408
RU - Federazione Russa 1.107
IT - Italia 953
CN - Cina 646
BR - Brasile 480
IE - Irlanda 382
VN - Vietnam 255
UA - Ucraina 252
CI - Costa d'Avorio 232
CA - Canada 154
IN - India 154
DE - Germania 146
FR - Francia 128
SE - Svezia 94
GB - Regno Unito 84
BD - Bangladesh 74
SN - Senegal 71
NG - Nigeria 63
KR - Corea 62
FI - Finlandia 43
PL - Polonia 40
NL - Olanda 34
MX - Messico 32
JP - Giappone 31
AR - Argentina 28
ES - Italia 28
BE - Belgio 26
IQ - Iraq 26
HK - Hong Kong 24
UZ - Uzbekistan 24
TR - Turchia 23
ZA - Sudafrica 22
CZ - Repubblica Ceca 16
CO - Colombia 15
IR - Iran 15
SA - Arabia Saudita 15
EC - Ecuador 14
ID - Indonesia 14
MA - Marocco 13
AT - Austria 12
IL - Israele 9
AE - Emirati Arabi Uniti 8
AU - Australia 8
CH - Svizzera 8
KE - Kenya 8
PK - Pakistan 8
TN - Tunisia 8
EG - Egitto 7
GR - Grecia 7
LB - Libano 7
PY - Paraguay 7
RO - Romania 7
PE - Perù 6
VE - Venezuela 6
HU - Ungheria 5
NO - Norvegia 5
TT - Trinidad e Tobago 5
AZ - Azerbaigian 4
BJ - Benin 4
DZ - Algeria 4
JM - Giamaica 4
LT - Lituania 4
MY - Malesia 4
PH - Filippine 4
RS - Serbia 4
BG - Bulgaria 3
CR - Costa Rica 3
DO - Repubblica Dominicana 3
JO - Giordania 3
SV - El Salvador 3
UY - Uruguay 3
AL - Albania 2
CL - Cile 2
ET - Etiopia 2
KG - Kirghizistan 2
KZ - Kazakistan 2
LU - Lussemburgo 2
LV - Lettonia 2
NI - Nicaragua 2
OM - Oman 2
PR - Porto Rico 2
TH - Thailandia 2
AM - Armenia 1
BH - Bahrain 1
BO - Bolivia 1
CG - Congo 1
CY - Cipro 1
EU - Europa 1
GA - Gabon 1
GD - Grenada 1
HR - Croazia 1
KH - Cambogia 1
LC - Santa Lucia 1
LY - Libia 1
MN - Mongolia 1
NP - Nepal 1
PT - Portogallo 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 12.959
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Città #
Singapore 869
Santa Clara 770
Dallas 747
Moscow 521
Chandler 453
San Jose 398
Dublin 382
Ashburn 317
Chicago 302
Jacksonville 250
Abidjan 232
Catania 229
Los Angeles 157
Boardman 144
Beijing 120
Cambridge 104
Lawrence 104
Lauterbourg 103
Nanjing 102
Andover 99
Council Bluffs 97
Kochi 89
Hefei 83
Toronto 83
New York 81
Ho Chi Minh City 73
Dakar 70
Grafing 68
Hanoi 62
Seoul 61
Palermo 60
Civitanova Marche 58
Wilmington 53
Buffalo 49
Des Moines 48
San Mateo 48
Milan 43
São Paulo 43
Montreal 32
Orem 32
Tokyo 30
Warsaw 30
Bari 29
Abuja 28
Lagos 28
Munich 28
Nanchang 28
Rome 28
Seattle 27
Brussels 25
Portland 24
The Dalles 24
Columbus 22
Saint Petersburg 22
Shenyang 22
Dong Ket 21
Belo Horizonte 19
Turku 19
Changsha 18
Hong Kong 18
Ottawa 18
Frankfurt am Main 17
San Giovanni la Punta 17
Santa Venerina 17
Chennai 16
Hebei 16
Johannesburg 16
Phoenix 16
Jiaxing 15
Messina 15
Tianjin 15
Bremen 14
Brooklyn 14
Houston 14
Tashkent 14
Aci Catena 13
Boston 13
Brno 13
Denver 13
Lappeenranta 13
Manchester 13
Rio de Janeiro 13
Da Nang 12
London 12
San Francisco 12
Stockholm 12
Baghdad 11
Brasília 11
Helsinki 11
Mexico City 11
Pune 11
Amsterdam 10
Falls Church 10
Haiphong 10
Poplar 10
Curitiba 9
Elk Grove Village 9
Tehran 9
Washington 9
Atlanta 8
Totale 8.638
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Nome #
A Custom DNA-Based NGS Panel for the Molecular Characterization of Patients With Diffuse Gliomas: Diagnostic and Therapeutic Applications 255
Clinical Implications of Discordant Early Molecular Responses in CML Patients Treated with Imatinib 229
An Optimized NGS Workflow Defines Genetically Based Prognostic Categories for Patients with Uveal Melanoma 213
Activation of the IGF axis in thyroid cancer: Implications for tumorigenesis and treatment 196
Activation of the s100a7/rage pathway by igf-1 contributes to angiogenesis in breast cancer 190
Mutational Analysis of BRCA1 and BRCA2 Genes in Breast Cancer Patients from Eastern Sicily 185
A novel system for semiautomatic sample processing in chronic myeloid leukaemia: Increasing throughput without impacting on molecular monitoring at time of sars-cov-2 pandemic 183
AKT Inhibitors: New Weapons in the Fight Against Breast Cancer? 180
BCR-ABL1 doubling-times and halving-times may predict CML response to tyrosine kinase inhibitors 173
High BCR-ABL/GUSISlevels at diagnosis of chronic phase CML are associated with unfavorable responses to standard-dose imatinib 172
Biomarkers and prognostic factors for malignant pleural mesothelioma 171
Additional Genetic Alterations and Clonal Evolution of MPNs with Double Mutations on the MPL Gene: Two Case Reports 170
Chk1 Inhibition Restores Inotuzumab Ozogamicin Citotoxicity in CD22-Positive Cells Expressing Mutant p53 166
ABL1-Directed Inhibitors for CML: Efficacy, Resistance and Future Perspectives 166
Non ABL-directed inhibitors as alternative treatment strategies for chronic myeloid leukemia 164
Efficacy of Dasatinib in a Very Elderly CML Patient Expressing a Rare E13a3 Bcr-Abl1 Fusion Transcript: A Case Report 164
Combined use of sonographic and elastosonographic parameters can improve the diagnostic accuracy in thyroid nodules at risk of malignancy at cytological examination 162
Impact of the Breakpoint Region on the Leukemogenic Potential and the TKI Responsiveness of Atypical BCR-ABL1 Transcripts 161
Colony-forming cell assay detecting the co-expression of JAK2 V617F and BCR-ABL1 in the same clone: A case report 159
Molecular Alterations in Thyroid Cancer: From Bench to Clinical Practice 158
B-ALL relapses after autologous stem cell transplantation associated with a shift from e1a2 to e14a2 BCR-ABL transcripts: A case report 157
BCR-ABL TYROSINE KINASE ACTIVITY MODULATES THE PHOSPHORYLATION, LOCALIZATION AND FUNCTION OF INTERFERON REGULATORY FACTOR 5 (IRF-5) IN CHRONIC MYELOID LEUKEMIA CELLS 152
Effect of combined epigenetic treatments and ectopic NIS expression on undifferentiated thyroid cancer cells 151
Efficacy of Nilotinib in a CML Patient Expressing the Three-way Complex Variant Translocation t(2;9;22) 151
Impact of Different Cell Counting Methods in Molecular Monitoring of Chronic Myeloid Leukemia Patients. 150
BCR-ABL Tyrosine Kinase Activity Modulates the Phosphorylation, Localization and Function of Interferon Regulatory Factor 5 (irf-5) in Chronic Myeloid Leukemia (CML) Cells 147
BCR-ABL tyrosine kinase activity modulates the phosphorylation and the localization of Interferon Regulatory Factor 5 (IRF-5)in Chronic Myeloid Leukemia cells 145
Altered expression of c-IAP1, survivin, and Smac contributes to chemotherapy resistance in thyroid cancer cells.Cancer Res 145
BCR-ABL residues interacting with ponatinib are critical to preserve the tumorigenic potential of the oncoprotein 144
New insights in thyroid cancer and p53 family proteins 143
Glucose-dependent effect of insulin receptor isoforms on tamoxifen antitumor activity in estrogen receptor-positive breast cancer cells 140
Next generation sequencing in a cohort of patients with rare sarcoma histotypes: A single institution experience 139
Mechanistic Translation of Melanoma Genetic Landscape in Enriched Pathways and Oncogenic Protein-Protein Interactions 139
Opportunities and challenges of liquid biopsy in thyroid cancer 133
Optimal Response in a Patient With CML Expressing BCR-ABL1 E6A2 Fusion Transcript With Nilotinib Therapy: A Case Report 133
Detection and clinical implications of a novel BCR-ABL1 E12A2 insertion/deletion in a CML patient expressing the E13A2 isoform 133
Molecular Analysis of Luminal Androgen Receptor Reveals Activated Pathways and Potential Therapeutic Targets in Breast Cancer 132
BCR-ABL TYROSINE KINASE ACTIVITY MODULATES THE PHOSPHORYLATION, LOCALIZATION AND BIOLOGICAL FUNCTION OF INTERFERON REGULATORY FACTOR 5 IN CHRONIC MYELOID LEUKEMIA CELLS 132
BCR-Abl tyrosine kinase activity modulates the expression of Interferon Regulatory Factor-5 in CML cells 130
Combined inhibition of bcl2 and bcr-abl1 exercises anti-leukemia activity but does not eradicate the primitive leukemic cells 130
Short-term adverse effects of anticancer drugs in patients with type 2 diabetes 128
In Silico Prediction of BRCA1 and BRCA2 Variants with Conflicting Clinical Interpretation in a Cohort of Breast Cancer Patients 126
Successful management of a pregnant patient with chronic myeloid leukemia receiving standard dose imatinib 122
High BCR::ABL1 Expression Defines CD34+ Cells with Significant Alterations in Signal Transduction, Short-Proliferative Potential and Self-Renewal Ability 121
Potential Therapeutic Targets for Luminal Androgen Receptor Breast Cancer: What We Know so Far 121
BCR-ABL tyrosine kinase activity modulates survivin expression via PI3K/AKT 121
No Benefit from Hydroxyurea Pre-Treatment in Frontline Chronic Myeloid Leukemia Therapy and Evidence of Quantitative Changes in the BCR::ABL1 Transcript Level 120
Rapid decline of philadelphia-positive metaphases after nilotinib treatment in a CML patient expressing a rare e14a3 BCR-ABL1 fusion transcript: A case report 119
Microenvironmental Determinants of Breast Cancer Metastasis: Focus on the Crucial Interplay Between Estrogen and Insulin/Insulin-Like Growth Factor Signaling 119
Pyrrolidinedithiocarbamate induces apoptosis in human acute myelogenous leukemic cells affecting NF-kappaB activity 118
Suppression of survivin induced by BCR-ABL/JAK2/STAT3 pathway sensitizes imatinib-resistant CML cells to different cytotoxic drugs 118
Computational and experimental characterization of critical amino acidic residues in the BCR-ABL kinase domain explaining TKIs resistance in patients with chronic myeloid leukemia 118
Prognostic and Therapeutic Roles of the Insulin Growth Factor System in Glioblastoma 116
BCR-ABL tyrosine kinase activity modulates Survivin expression in CML cells 115
Computational and Experimental Characterization of Two Nuclear Localization Signals and a Nuclear Export Signal that modulate BCR intracellular localization 114
Molecular pathogenesis and treatment perspectives for hypereosinophilia and hypereosinophilic syndromes 113
c-IAP1, Survivin and Smac contribute to chemotherapy resistance in undifferentiated thyroid cancer cells 111
Targeting BCL-2 as a therapeutic strategy for primary p210BCR-ABL1-positive B-ALL cells 110
Possible role of the transcription factor interferon regulatory factor 1 (IRF-1) in the regulation of ornithine decarboxylase (ODC) gene expression during IFN gamma macrophage activation 109
Implications of antidepressants use in breast cancer: A brief review 108
Multiple primary malignances managed with surgical excision: a case report with next generation sequencing analysis 108
Apoptosi mediata da Fas in cellule monocitiche umane 106
Single-Cell Analysis in the Omics Era: Technologies and Applications in Cancer 101
The PU.1 transcription factor induces cyclin D2 expression in U937 cells 99
IRF5 is a target of BCR-ABL kinase activity and reduces CML cell proliferation. 96
SELECTIVE INHIHBITION OF LEUKEMIA CELL PROLIFERATION BY BCR-ABL ANTISENSE OLIGODEOXYNUCLEOTIDES SCIENCE 95
Silencing of survivin induced by BCR-ABL/JAK2/STAT3 pathway kills CML cells and sensitizes IM-resistant clones to hydroxyurea 92
Diagnosis of Chronic Myeloid Leukemia Early in Pregnancy 92
HER2-Low Expression in Male Breast Cancer: Results from a Multicenter Series in Italy 90
UNA INSERZIONE NEL DOMINIO TIROSIN-CHINASICO DI BCR-ABL POTREBBE CONTRIBUIRE ALLA RESISTENZA AD IMATINIB MESILATO DI PAZIENTI AFFETTI DA LEUCEMIA MIELOIDE CRONICA 90
Ruolo del transcription factor interferon regulatory factor 1 (IRF-1) nella regolazione dell’espressione del gene della ornitina decarbossilasi durante l’attivazione di macrofagi umani mediata da IFN-gamma 90
High BCR-ABL/GUS(IS) Levels at Diagnosis Are Associated with Unfavorable Responses to Standard Dose Imatinib 89
The Insulin/IGF System in Colorectal Cancer Development and Resistance to Therapy 89
PI3K inhibition in breast cancer: Identifying and overcoming different flavors of resistance 89
Roles of Interferon Regulatory Factors in Chronic Myeloid Leukemia 87
Espressione e funzione di OMI/HTRA2 in tumori solidi ed ematologici 87
Ruolo delle IAPs e di Smac/DIABLO nella resistenza ai farmaci antiblastici di cellule di carcinoma indifferenziato della tiroide 87
Long-acting insulin analogs and cancer 86
ROLE OF INTERFERON REGULATORY FACTOR-1 (IRF-1) IN MONOCYTE FAS EXPRESSION AND FAS-MEDIATED APOPTOSIS 84
Delayed use of eribulin in a heavily pretreated liposarcoma patient, previously misdiagnosed as leiomyosarcoma 84
High BCR-ABL expression levels at diagnosis may predict unfavorable CML responses to Imatinib therapy 82
POSITIVE AUTOREGULATION OF C-MYB BINDING SITES IN THE 5’ FLANKING REGION OF THE HUMAN C-MYB GENE 81
Experimental and Computational Characterization of Amino Acidic Residues in the BCR-ABL kinase domain contributing to TKI resistance in patients with Chronic Myeloid Leukemia 78
Role of NFkB in cytokine expression in normal Bone Marrow Cells 78
L’attività tirosin-chinasica di BCR/Abl modula l’espressione di IRF-5 78
Computational and biological characterization of nuclear import/export signals of the human BCR protein 78
High BCR-ABL/GUSIS Levels At Diagnosis Are Associated With Unfavorable Responses To Imatinib 78
Molecular dynamics simulations reveal the role of five BCR-ABL kinase domain critical residues in TKIS binding 76
Hyperdiploidy associated with a high BCR-ABL transcript level may identify patients at risk of progression in chronic myeloid leukemia 75
High BCR-ABLIS expression at diagnosis and after 3 and 6 months of treatment are associated with unfavourable responses to Imatinib 75
Modelling of the ABL and ARG proteins predicts two functionally critical regions that are natively unfolded 75
HIGH BCR-ABL LEVELS AT DIAGNOSIS ARE ASSOCIATED WITH UNFAVORABLE RESPONS- ES TO IMATINIB 74
Ruolo funzionale dell’Interferon Regulatory Factor 1 (IRF-1) nell’attivazione di macrofagi umani mediata dal IFN 73
ROLE OF INTERFERON REGULATORY FACTOR 1 IN MONOCYTE/MACROPHAGE DIFFERENTIATION 71
The other side of the coin: dissecting molecular mechanisms behind hereditary breast cancer in search of therapeutic opportunities 71
Role of Interferon Regulatory Factor-5 in Chronic Myeloid Leucemia 69
Role of Interferon Regulatory Factor-5 (IRF-5) in solid and haematological malignancies 69
Transcriptional control of apoptosis related genes in Acute Myeloid Leukemia (AML) cells 68
IRF5 promotes the proliferation of human thyroid cancer cells. 68
Silencing of survivin induced by BCR/ABL/JAK2/STAT3 pathway killes CML cells and sensitizes IM-resistant clones to hydroxyurea 67
Totale 12.115
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Categoria #
all - tutte 44.177
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 44.177
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022695 0 113 18 11 126 7 115 26 64 10 33 172
2022/20231.478 118 101 53 180 89 231 19 261 323 21 51 31
2023/2024785 64 106 36 36 34 189 7 59 5 25 155 69
2024/20252.943 47 447 126 147 599 384 178 82 191 240 309 193
2025/20265.550 331 286 819 374 853 1.244 619 109 296 316 176 127
2026/2027384 226 158 0 0 0 0 0 0 0 0 0 0
Totale 13.183