IRIS
MANZELLA, LIVIA
 Distribuzione geografica
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Continente #
NA - Nord America 5.546
EU - Europa 3.305
AS - Asia 2.809
SA - Sud America 554
AF - Africa 436
OC - Oceania 8
Continente sconosciuto - Info sul continente non disponibili 2
Totale 12.660
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Nazione #
US - Stati Uniti d'America 5.352
SG - Singapore 1.408
RU - Federazione Russa 1.107
IT - Italia 913
CN - Cina 645
BR - Brasile 479
IE - Irlanda 382
VN - Vietnam 253
UA - Ucraina 252
CI - Costa d'Avorio 232
IN - India 154
CA - Canada 150
DE - Germania 146
FR - Francia 128
GB - Regno Unito 84
SN - Senegal 71
BD - Bangladesh 64
NG - Nigeria 63
KR - Corea 62
FI - Finlandia 43
SE - Svezia 42
PL - Polonia 40
NL - Olanda 33
JP - Giappone 31
MX - Messico 31
AR - Argentina 28
ES - Italia 28
BE - Belgio 26
IQ - Iraq 26
HK - Hong Kong 24
UZ - Uzbekistan 24
TR - Turchia 22
ZA - Sudafrica 22
CZ - Repubblica Ceca 16
SA - Arabia Saudita 14
ID - Indonesia 13
MA - Marocco 13
AT - Austria 12
EC - Ecuador 12
IR - Iran 12
CO - Colombia 11
IL - Israele 9
AE - Emirati Arabi Uniti 8
AU - Australia 8
CH - Svizzera 8
KE - Kenya 8
PK - Pakistan 8
TN - Tunisia 8
EG - Egitto 7
GR - Grecia 7
LB - Libano 7
PY - Paraguay 7
RO - Romania 7
PE - Perù 6
HU - Ungheria 5
NO - Norvegia 5
VE - Venezuela 5
AZ - Azerbaigian 4
BJ - Benin 4
LT - Lituania 4
MY - Malesia 4
RS - Serbia 4
BG - Bulgaria 3
DO - Repubblica Dominicana 3
DZ - Algeria 3
JM - Giamaica 3
JO - Giordania 3
UY - Uruguay 3
AL - Albania 2
CL - Cile 2
ET - Etiopia 2
KG - Kirghizistan 2
KZ - Kazakistan 2
LU - Lussemburgo 2
LV - Lettonia 2
NI - Nicaragua 2
OM - Oman 2
PR - Porto Rico 2
AM - Armenia 1
BH - Bahrain 1
BO - Bolivia 1
CG - Congo 1
CR - Costa Rica 1
CY - Cipro 1
EU - Europa 1
GA - Gabon 1
GD - Grenada 1
HR - Croazia 1
KH - Cambogia 1
LY - Libia 1
MN - Mongolia 1
NP - Nepal 1
PH - Filippine 1
PT - Portogallo 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
TT - Trinidad e Tobago 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 12.660
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Città #
Singapore 869
Santa Clara 763
Dallas 745
Moscow 521
Chandler 453
San Jose 395
Dublin 382
Ashburn 312
Chicago 292
Jacksonville 250
Abidjan 232
Catania 223
Los Angeles 147
Boardman 144
Beijing 120
Cambridge 104
Lawrence 104
Lauterbourg 103
Nanjing 102
Andover 99
Kochi 89
Hefei 83
Toronto 82
New York 77
Ho Chi Minh City 72
Dakar 70
Grafing 68
Council Bluffs 63
Hanoi 61
Seoul 61
Civitanova Marche 58
Palermo 55
Wilmington 51
Buffalo 48
Des Moines 48
San Mateo 48
São Paulo 42
Milan 33
Montreal 32
Orem 32
Tokyo 30
Warsaw 30
Bari 29
Abuja 28
Lagos 28
Munich 28
Nanchang 28
Seattle 27
Brussels 25
Portland 24
The Dalles 24
Columbus 22
Rome 22
Saint Petersburg 22
Shenyang 22
Dong Ket 21
Belo Horizonte 19
Turku 19
Changsha 18
Hong Kong 18
Ottawa 18
Frankfurt am Main 17
San Giovanni la Punta 17
Santa Venerina 17
Chennai 16
Hebei 16
Johannesburg 16
Phoenix 16
Jiaxing 15
Messina 15
Tianjin 15
Bremen 14
Houston 14
Tashkent 14
Aci Catena 13
Brno 13
Brooklyn 13
Denver 13
Lappeenranta 13
Manchester 13
Rio de Janeiro 13
Boston 12
Da Nang 12
London 12
Stockholm 12
Baghdad 11
Brasília 11
Helsinki 11
Pune 11
San Francisco 11
Amsterdam 10
Falls Church 10
Haiphong 10
Mexico City 10
Poplar 10
Curitiba 9
Elk Grove Village 9
Atlanta 8
Jakarta 8
Leawood 8
Totale 8.523
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Nome #
A Custom DNA-Based NGS Panel for the Molecular Characterization of Patients With Diffuse Gliomas: Diagnostic and Therapeutic Applications 251
Clinical Implications of Discordant Early Molecular Responses in CML Patients Treated with Imatinib 228
An Optimized NGS Workflow Defines Genetically Based Prognostic Categories for Patients with Uveal Melanoma 208
Activation of the IGF axis in thyroid cancer: Implications for tumorigenesis and treatment 194
Activation of the s100a7/rage pathway by igf-1 contributes to angiogenesis in breast cancer 188
Mutational Analysis of BRCA1 and BRCA2 Genes in Breast Cancer Patients from Eastern Sicily 184
A novel system for semiautomatic sample processing in chronic myeloid leukaemia: Increasing throughput without impacting on molecular monitoring at time of sars-cov-2 pandemic 182
AKT Inhibitors: New Weapons in the Fight Against Breast Cancer? 177
High BCR-ABL/GUSISlevels at diagnosis of chronic phase CML are associated with unfavorable responses to standard-dose imatinib 170
BCR-ABL1 doubling-times and halving-times may predict CML response to tyrosine kinase inhibitors 169
Biomarkers and prognostic factors for malignant pleural mesothelioma 168
Additional Genetic Alterations and Clonal Evolution of MPNs with Double Mutations on the MPL Gene: Two Case Reports 167
Chk1 Inhibition Restores Inotuzumab Ozogamicin Citotoxicity in CD22-Positive Cells Expressing Mutant p53 164
Efficacy of Dasatinib in a Very Elderly CML Patient Expressing a Rare E13a3 Bcr-Abl1 Fusion Transcript: A Case Report 161
ABL1-Directed Inhibitors for CML: Efficacy, Resistance and Future Perspectives 161
Non ABL-directed inhibitors as alternative treatment strategies for chronic myeloid leukemia 160
Combined use of sonographic and elastosonographic parameters can improve the diagnostic accuracy in thyroid nodules at risk of malignancy at cytological examination 160
Impact of the Breakpoint Region on the Leukemogenic Potential and the TKI Responsiveness of Atypical BCR-ABL1 Transcripts 159
Colony-forming cell assay detecting the co-expression of JAK2 V617F and BCR-ABL1 in the same clone: A case report 158
B-ALL relapses after autologous stem cell transplantation associated with a shift from e1a2 to e14a2 BCR-ABL transcripts: A case report 156
Molecular Alterations in Thyroid Cancer: From Bench to Clinical Practice 154
Effect of combined epigenetic treatments and ectopic NIS expression on undifferentiated thyroid cancer cells 150
BCR-ABL TYROSINE KINASE ACTIVITY MODULATES THE PHOSPHORYLATION, LOCALIZATION AND FUNCTION OF INTERFERON REGULATORY FACTOR 5 (IRF-5) IN CHRONIC MYELOID LEUKEMIA CELLS 149
Impact of Different Cell Counting Methods in Molecular Monitoring of Chronic Myeloid Leukemia Patients. 147
Efficacy of Nilotinib in a CML Patient Expressing the Three-way Complex Variant Translocation t(2;9;22) 145
Altered expression of c-IAP1, survivin, and Smac contributes to chemotherapy resistance in thyroid cancer cells.Cancer Res 144
BCR-ABL Tyrosine Kinase Activity Modulates the Phosphorylation, Localization and Function of Interferon Regulatory Factor 5 (irf-5) in Chronic Myeloid Leukemia (CML) Cells 144
New insights in thyroid cancer and p53 family proteins 142
BCR-ABL tyrosine kinase activity modulates the phosphorylation and the localization of Interferon Regulatory Factor 5 (IRF-5)in Chronic Myeloid Leukemia cells 141
BCR-ABL residues interacting with ponatinib are critical to preserve the tumorigenic potential of the oncoprotein 140
Mechanistic Translation of Melanoma Genetic Landscape in Enriched Pathways and Oncogenic Protein-Protein Interactions 138
Next generation sequencing in a cohort of patients with rare sarcoma histotypes: A single institution experience 136
Opportunities and challenges of liquid biopsy in thyroid cancer 131
Optimal Response in a Patient With CML Expressing BCR-ABL1 E6A2 Fusion Transcript With Nilotinib Therapy: A Case Report 131
Molecular Analysis of Luminal Androgen Receptor Reveals Activated Pathways and Potential Therapeutic Targets in Breast Cancer 130
BCR-ABL TYROSINE KINASE ACTIVITY MODULATES THE PHOSPHORYLATION, LOCALIZATION AND BIOLOGICAL FUNCTION OF INTERFERON REGULATORY FACTOR 5 IN CHRONIC MYELOID LEUKEMIA CELLS 129
Detection and clinical implications of a novel BCR-ABL1 E12A2 insertion/deletion in a CML patient expressing the E13A2 isoform 129
BCR-Abl tyrosine kinase activity modulates the expression of Interferon Regulatory Factor-5 in CML cells 128
Combined inhibition of bcl2 and bcr-abl1 exercises anti-leukemia activity but does not eradicate the primitive leukemic cells 128
Glucose-dependent effect of insulin receptor isoforms on tamoxifen antitumor activity in estrogen receptor-positive breast cancer cells 128
Short-term adverse effects of anticancer drugs in patients with type 2 diabetes 127
In Silico Prediction of BRCA1 and BRCA2 Variants with Conflicting Clinical Interpretation in a Cohort of Breast Cancer Patients 121
High BCR::ABL1 Expression Defines CD34+ Cells with Significant Alterations in Signal Transduction, Short-Proliferative Potential and Self-Renewal Ability 120
Potential Therapeutic Targets for Luminal Androgen Receptor Breast Cancer: What We Know so Far 120
BCR-ABL tyrosine kinase activity modulates survivin expression via PI3K/AKT 120
Successful management of a pregnant patient with chronic myeloid leukemia receiving standard dose imatinib 119
Rapid decline of philadelphia-positive metaphases after nilotinib treatment in a CML patient expressing a rare e14a3 BCR-ABL1 fusion transcript: A case report 118
Pyrrolidinedithiocarbamate induces apoptosis in human acute myelogenous leukemic cells affecting NF-kappaB activity 117
Microenvironmental Determinants of Breast Cancer Metastasis: Focus on the Crucial Interplay Between Estrogen and Insulin/Insulin-Like Growth Factor Signaling 115
No Benefit from Hydroxyurea Pre-Treatment in Frontline Chronic Myeloid Leukemia Therapy and Evidence of Quantitative Changes in the BCR::ABL1 Transcript Level 114
Prognostic and Therapeutic Roles of the Insulin Growth Factor System in Glioblastoma 114
Computational and Experimental Characterization of Two Nuclear Localization Signals and a Nuclear Export Signal that modulate BCR intracellular localization 113
Suppression of survivin induced by BCR-ABL/JAK2/STAT3 pathway sensitizes imatinib-resistant CML cells to different cytotoxic drugs 112
BCR-ABL tyrosine kinase activity modulates Survivin expression in CML cells 112
Molecular pathogenesis and treatment perspectives for hypereosinophilia and hypereosinophilic syndromes 110
Possible role of the transcription factor interferon regulatory factor 1 (IRF-1) in the regulation of ornithine decarboxylase (ODC) gene expression during IFN gamma macrophage activation 109
c-IAP1, Survivin and Smac contribute to chemotherapy resistance in undifferentiated thyroid cancer cells 109
Targeting BCL-2 as a therapeutic strategy for primary p210BCR-ABL1-positive B-ALL cells 108
Implications of antidepressants use in breast cancer: A brief review 107
Multiple primary malignances managed with surgical excision: a case report with next generation sequencing analysis 105
Apoptosi mediata da Fas in cellule monocitiche umane 104
Single-Cell Analysis in the Omics Era: Technologies and Applications in Cancer 98
The PU.1 transcription factor induces cyclin D2 expression in U937 cells 97
SELECTIVE INHIHBITION OF LEUKEMIA CELL PROLIFERATION BY BCR-ABL ANTISENSE OLIGODEOXYNUCLEOTIDES SCIENCE 95
IRF5 is a target of BCR-ABL kinase activity and reduces CML cell proliferation. 95
Diagnosis of Chronic Myeloid Leukemia Early in Pregnancy 90
HER2-Low Expression in Male Breast Cancer: Results from a Multicenter Series in Italy 89
UNA INSERZIONE NEL DOMINIO TIROSIN-CHINASICO DI BCR-ABL POTREBBE CONTRIBUIRE ALLA RESISTENZA AD IMATINIB MESILATO DI PAZIENTI AFFETTI DA LEUCEMIA MIELOIDE CRONICA 89
The Insulin/IGF System in Colorectal Cancer Development and Resistance to Therapy 89
Silencing of survivin induced by BCR-ABL/JAK2/STAT3 pathway kills CML cells and sensitizes IM-resistant clones to hydroxyurea 88
Ruolo del transcription factor interferon regulatory factor 1 (IRF-1) nella regolazione dell’espressione del gene della ornitina decarbossilasi durante l’attivazione di macrofagi umani mediata da IFN-gamma 88
High BCR-ABL/GUS(IS) Levels at Diagnosis Are Associated with Unfavorable Responses to Standard Dose Imatinib 86
Roles of Interferon Regulatory Factors in Chronic Myeloid Leukemia 86
PI3K inhibition in breast cancer: Identifying and overcoming different flavors of resistance 86
Ruolo delle IAPs e di Smac/DIABLO nella resistenza ai farmaci antiblastici di cellule di carcinoma indifferenziato della tiroide 86
Espressione e funzione di OMI/HTRA2 in tumori solidi ed ematologici 85
ROLE OF INTERFERON REGULATORY FACTOR-1 (IRF-1) IN MONOCYTE FAS EXPRESSION AND FAS-MEDIATED APOPTOSIS 83
Long-acting insulin analogs and cancer 83
Delayed use of eribulin in a heavily pretreated liposarcoma patient, previously misdiagnosed as leiomyosarcoma 83
High BCR-ABL expression levels at diagnosis may predict unfavorable CML responses to Imatinib therapy 81
POSITIVE AUTOREGULATION OF C-MYB BINDING SITES IN THE 5’ FLANKING REGION OF THE HUMAN C-MYB GENE 80
Role of NFkB in cytokine expression in normal Bone Marrow Cells 77
Computational and biological characterization of nuclear import/export signals of the human BCR protein 77
Experimental and Computational Characterization of Amino Acidic Residues in the BCR-ABL kinase domain contributing to TKI resistance in patients with Chronic Myeloid Leukemia 76
L’attività tirosin-chinasica di BCR/Abl modula l’espressione di IRF-5 76
Molecular dynamics simulations reveal the role of five BCR-ABL kinase domain critical residues in TKIS binding 76
High BCR-ABL/GUSIS Levels At Diagnosis Are Associated With Unfavorable Responses To Imatinib 75
High BCR-ABLIS expression at diagnosis and after 3 and 6 months of treatment are associated with unfavourable responses to Imatinib 73
HIGH BCR-ABL LEVELS AT DIAGNOSIS ARE ASSOCIATED WITH UNFAVORABLE RESPONS- ES TO IMATINIB 73
Modelling of the ABL and ARG proteins predicts two functionally critical regions that are natively unfolded 73
Hyperdiploidy associated with a high BCR-ABL transcript level may identify patients at risk of progression in chronic myeloid leukemia 72
Ruolo funzionale dell’Interferon Regulatory Factor 1 (IRF-1) nell’attivazione di macrofagi umani mediata dal IFN 72
Computational and experimental characterization of critical amino acidic residues in the BCR-ABL kinase domain explaining TKIs resistance in patients with chronic myeloid leukemia 71
The other side of the coin: dissecting molecular mechanisms behind hereditary breast cancer in search of therapeutic opportunities 71
ROLE OF INTERFERON REGULATORY FACTOR 1 IN MONOCYTE/MACROPHAGE DIFFERENTIATION 69
Role of Interferon Regulatory Factor-5 in Chronic Myeloid Leucemia 69
Transcriptional control of apoptosis related genes in Acute Myeloid Leukemia (AML) cells 68
Role of Interferon Regulatory Factor-5 (IRF-5) in solid and haematological malignancies 67
The catalytic activity of BCR-ABL modulates survivin expression in chronic myelogenous leukemia cell lines 66
Silencing of survivin induced by BCR/ABL/JAK2/STAT3 pathway killes CML cells and sensitizes IM-resistant clones to hydroxyurea 66
Totale 11.847
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Categoria #
all - tutte 42.277
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 42.277
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022765 70 113 18 11 126 7 115 26 64 10 33 172
2022/20231.478 118 101 53 180 89 231 19 261 323 21 51 31
2023/2024785 64 106 36 36 34 189 7 59 5 25 155 69
2024/20252.943 47 447 126 147 599 384 178 82 191 240 309 193
2025/20265.550 331 286 819 374 853 1.244 619 109 296 316 176 127
2026/202783 83 0 0 0 0 0 0 0 0 0 0 0
Totale 12.882