IRIS
INTAGLIATA, SEBASTIANO
 Distribuzione geografica
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Continente #
NA - Nord America 2.526
EU - Europa 1.340
AS - Asia 1.157
SA - Sud America 275
AF - Africa 176
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5.477
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Nazione #
US - Stati Uniti d'America 2.482
IT - Italia 823
SG - Singapore 587
CN - Cina 357
BR - Brasile 247
IE - Irlanda 193
CI - Costa d'Avorio 101
DE - Germania 69
VN - Vietnam 62
RU - Federazione Russa 48
SN - Senegal 47
KR - Corea 40
UA - Ucraina 35
CA - Canada 31
GB - Regno Unito 27
FR - Francia 26
FI - Finlandia 23
JP - Giappone 20
ES - Italia 17
PL - Polonia 17
IN - India 16
BD - Bangladesh 12
CZ - Repubblica Ceca 12
IQ - Iraq 12
AR - Argentina 10
NL - Olanda 9
SE - Svezia 9
TR - Turchia 9
ZA - Sudafrica 8
HK - Hong Kong 7
MX - Messico 7
BJ - Benin 6
CH - Svizzera 6
ID - Indonesia 6
LT - Lituania 5
VE - Venezuela 5
AT - Austria 4
EC - Ecuador 4
EG - Egitto 4
IR - Iran 4
UZ - Uzbekistan 4
AZ - Azerbaigian 3
CL - Cile 3
DO - Repubblica Dominicana 3
GR - Grecia 3
KE - Kenya 3
RO - Romania 3
AE - Emirati Arabi Uniti 2
AL - Albania 2
AU - Australia 2
BG - Bulgaria 2
BY - Bielorussia 2
CM - Camerun 2
CO - Colombia 2
GT - Guatemala 2
GY - Guiana 2
JO - Giordania 2
KG - Kirghizistan 2
LU - Lussemburgo 2
MA - Marocco 2
NG - Nigeria 2
NP - Nepal 2
OM - Oman 2
PK - Pakistan 2
BE - Belgio 1
HU - Ungheria 1
IL - Israele 1
JM - Giamaica 1
KZ - Kazakistan 1
LB - Libano 1
MT - Malta 1
PE - Perù 1
PS - Palestinian Territory 1
PY - Paraguay 1
SA - Arabia Saudita 1
TN - Tunisia 1
TW - Taiwan 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 5.477
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Città #
Dallas 634
Singapore 295
Santa Clara 285
Chandler 276
Catania 204
Dublin 189
Chicago 178
Ashburn 124
Abidjan 101
Beijing 100
Boardman 84
Hefei 79
Houston 68
Cambridge 51
Lawrence 48
Dakar 47
Andover 46
Seoul 39
Redmond 38
Naples 37
Los Angeles 36
Rome 35
Civitanova Marche 34
São Paulo 33
Jacksonville 30
Munich 26
Palermo 23
Des Moines 22
Wilmington 22
Nanjing 21
Milan 20
Tokyo 20
New York 19
Boydton 18
Buffalo 18
Ho Chi Minh City 18
The Dalles 18
Bremen 17
Columbus 17
Hanoi 16
Dong Ket 15
Messina 15
Council Bluffs 14
Toronto 14
Seattle 12
Turku 12
Warsaw 11
Salerno 10
Civitavecchia 9
Pozzallo 9
Viagrande 9
Brooklyn 8
Gravina di Catania 8
Hebei 8
Aci Catena 7
Baghdad 7
Brno 7
Gela 7
Lappeenranta 7
London 7
Moscow 7
Ottawa 7
Saint Petersburg 7
San Francisco 7
Siracusa 7
Stockholm 7
Turin 7
Barcelona 6
Cotonou 6
Denver 6
Ferrara di Monte Baldo 6
Foggia 6
Fortaleza 6
Garbagnate Milanese 6
Goiânia 6
Johannesburg 6
Washington 6
Amsterdam 5
Atlanta 5
Brasília 5
Curitiba 5
Fairfield 5
Hong Kong 5
Jakarta 5
Nanchang 5
Padova 5
Poplar 5
Raffadali 5
Reggio Calabria 5
Santa Maria di Licodia 5
Shenyang 5
Tremestieri Etneo 5
Ankara 4
Chennai 4
Florence 4
Helsinki 4
Maceió 4
Madrid 4
Mexico City 4
Milazzo 4
Totale 3.798
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Nome #
Haloperidol drug repurposing unveils ferroptosis involvement in breast cancer cells 227
Design, synthesis, and pharmacological evaluation of NO donor-sigma receptors hybrids for the treatment of cancer 155
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 149
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 142
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 141
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 140
Solid lipid nanoparticles loading idebenone ester with pyroglutamic acid: In vitro antioxidant activity and in vivo topical efficacy 115
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 115
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 114
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 110
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 109
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 107
New arylethanolimidazole derivatives as HO-1 inhibitors with cytotoxicity against MCF-7 breast cancer cells 106
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 104
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells 102
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 102
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 101
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 101
Combination of heme oxygenase-1 inhibitors and temozolomide to improve the anticancer effect in glioblastoma 100
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 100
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 99
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 94
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 94
The analgesic potential of glycosides derived from medicinal plants 92
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 92
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 91
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 90
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 90
In vitro antioxidant and anti-glycation activity of resveratrol and its novel triester with trolox 89
Correction to Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 87
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 87
Ginseng and heme oxygenase-1: The link between an old herb and a new protective system 87
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 87
Novel mutual prodrug of 5-fluorouracil and heme oxygenase-1 inhibitor (5-FU/HO-1 hybrid): design and preliminary in vitro evaluation 86
Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In Vivo 86
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 84
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 82
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 81
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 81
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 81
Characterization of sigma 1 receptor antagonist CM-304 and its analog, AZ-66: Novel therapeutics against allodynia and induced pain 80
Discovery of 3-(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligands 77
Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats 76
Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain 73
Benzimidazolone-based selective σ2 receptor ligands: Synthesis and pharmacological evaluation 73
Divergent cytotoxic and metabolically stimulative functions of sigma-2 receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives 71
Bioanalytical method development and pharmacokinetics of MCI-92, a sigma-1 receptor ligand 70
Exploring 1-adamantanamine as an alternative amine moiety for metabolically labile azepane ring in newly synthesized benzo[d]thiazol-2(3H)one σ receptor ligands 64
Synthesis and in Vitro Evaluation of CAPE Derivatives as Ferroptosis Inducers in Triple Negative Breast Cancer 63
In vitro and in silico analysis of imatinib analogues as anti- Trypanosoma cruzi drug candidates 60
Strategies to improve resveratrol systemic and topical bioavailability: An update 60
Lauric acid-based thermosensitive delivery system for the treatment of head and neck squamous cell carcinoma 57
New alkylpiperazines as 5-HT7R ligands 56
New thienopyrimidine and quinazoline derivatives as potential 5-HT7 receptor ligands. 56
The Inhibition of Neuropathic Pain Incited by Nerve Injury and Accompanying Mood Disorders by New Heme Oxygenase-1 Inducers: Mechanisms Implicated 55
New 5-Ht7 Receptor Ligands As Potential Antidepressant Agents. 55
Novel selective ligands for the serotonergic 5-HT7 receptor: tricyclic derivatives Bearing the pyrimido-4(3H)-one ring 52
New homo and hetero bis-arylpiperazine and bis-benzylpiperazine derivatives as 5-HT7R selective ligands: design and synthesis 51
New alkylpiperazines as 5-HT7R ligands 50
Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT1A and 5-HT7 receptor ligands 49
Thieno[3,2-d]pyrimidine as a scaffold for 5-HT7 receptor ligands 48
UPLC-MS/MS method for the quantification of MCI-77, a novel sigma-1 receptor ligand, and its application to pharmacokinetic studies 46
Laboratory-Scale Semipreparative Enantioresolution of Phenylethanolic-Azole Heme Oxygenase-1 Inhibitors 43
Novel benzothiazolones and benzoxazolones-based σ receptor ligands: synthesis and preliminary pharmacological evaluation against allodynia 37
Totale 5.622
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Categoria #
all - tutte 19.184
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 19.184
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021136 0 0 0 0 54 6 14 4 6 10 23 19
2021/2022507 36 57 59 16 67 17 69 33 17 27 11 98
2022/2023857 69 74 38 116 67 126 3 141 147 15 52 9
2023/2024439 20 52 21 22 48 110 5 28 1 18 65 49
2024/20251.659 24 255 67 134 294 150 168 51 126 144 138 108
2025/20261.633 216 150 733 190 344 0 0 0 0 0 0 0
Totale 5.622