IRIS
INTAGLIATA, SEBASTIANO
 Distribuzione geografica
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Continente #
NA - Nord America 948
EU - Europa 901
AF - Africa 129
AS - Asia 113
OC - Oceania 2
SA - Sud America 1
Totale 2.094
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Nazione #
US - Stati Uniti d'America 926
IT - Italia 533
IE - Irlanda 190
CI - Costa d'Avorio 77
CN - Cina 76
SN - Senegal 47
RU - Federazione Russa 42
DE - Germania 38
UA - Ucraina 29
CA - Canada 22
FR - Francia 19
VN - Vietnam 17
GB - Regno Unito 11
SG - Singapore 7
CH - Svizzera 6
IN - India 6
PL - Polonia 6
ES - Italia 5
GR - Grecia 3
RO - Romania 3
SE - Svezia 3
AU - Australia 2
CM - Camerun 2
CZ - Repubblica Ceca 2
FI - Finlandia 2
HK - Hong Kong 2
LU - Lussemburgo 2
NG - Nigeria 2
NL - Olanda 2
AT - Austria 1
BE - Belgio 1
BG - Bulgaria 1
BY - Bielorussia 1
CL - Cile 1
EG - Egitto 1
HU - Ungheria 1
IQ - Iraq 1
IR - Iran 1
KR - Corea 1
LB - Libano 1
TW - Taiwan 1
Totale 2.094
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Città #
Chandler 276
Dublin 186
Catania 121
Abidjan 77
Ashburn 67
Houston 66
Cambridge 51
Lawrence 48
Dakar 47
Andover 46
Redmond 38
Jacksonville 30
Rome 24
Des Moines 22
Wilmington 22
Nanjing 20
Palermo 20
Boydton 18
Bremen 17
Dong Ket 15
Toronto 14
Boardman 11
Seattle 11
Milan 10
Beijing 9
Civitavecchia 9
Messina 9
Hebei 8
Gela 7
Ottawa 7
Saint Petersburg 7
Siracusa 7
Ferrara di Monte Baldo 6
Foggia 6
Moscow 6
Fairfield 5
Nanchang 5
Padova 5
Raffadali 5
Reggio Calabria 5
Shenyang 5
Milazzo 4
Vicenza 4
Washington 4
Bucharest 3
Changsha 3
Ferrara 3
Gravina di Catania 3
Gunzenhausen 3
Latina 3
Los Angeles 3
Lucca 3
Madrid 3
Mascalucia 3
Modica 3
New Haven 3
Norwalk 3
Novara 3
Paris 3
Pune 3
Rimini 3
Roccalumera 3
San Mateo 3
Turin 3
Villamagna 3
Abuja 2
Cagliari 2
Cergy 2
Dallas 2
Esslingen am Neckar 2
Floridia 2
Froges 2
Giardini-Naxos 2
Hanoi 2
Jiaxing 2
Jinan 2
Kraków 2
Manduria 2
Naples 2
New Orleans 2
New York 2
Phoenix 2
Providence 2
Salerno 2
San Francisco 2
Tianjin 2
Torregrotta 2
Tusa 2
Valencia 2
Woodbridge 2
Wroclaw 2
Aci Castello 1
Aci Catena 1
Acireale 1
Agropoli 1
Alcamo 1
Ann Arbor 1
Ardabil 1
Atripalda 1
Bronte 1
Totale 1.504
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Nome #
Design, synthesis, and pharmacological evaluation of NO donor-sigma receptors hybrids for the treatment of cancer 92
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 80
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 74
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 66
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 64
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 62
Solid lipid nanoparticles loading idebenone ester with pyroglutamic acid: In vitro antioxidant activity and in vivo topical efficacy 61
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 61
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 60
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 57
New arylethanolimidazole derivatives as HO-1 inhibitors with cytotoxicity against MCF-7 breast cancer cells 57
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 53
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 52
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 50
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 47
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 47
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 47
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 46
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 45
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 44
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 42
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 41
Novel mutual prodrug of 5-fluorouracil and heme oxygenase-1 inhibitor (5-FU/HO-1 hybrid): design and preliminary in vitro evaluation 40
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 39
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 38
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 38
Ginseng and heme oxygenase-1: The link between an old herb and a new protective system 38
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 37
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 37
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 37
Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats 36
The analgesic potential of glycosides derived from medicinal plants 36
Exploring 1-adamantanamine as an alternative amine moiety for metabolically labile azepane ring in newly synthesized benzo[d]thiazol-2(3H)one σ receptor ligands 36
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 35
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 33
Characterization of sigma 1 receptor antagonist CM-304 and its analog, AZ-66: Novel therapeutics against allodynia and induced pain 32
Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In Vivo 32
Divergent cytotoxic and metabolically stimulative functions of sigma-2 receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives 30
In vitro antioxidant and anti-glycation activity of resveratrol and its novel triester with trolox 30
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 29
Benzimidazolone-based selective σ2 receptor ligands: Synthesis and pharmacological evaluation 28
Bioanalytical method development and pharmacokinetics of MCI-92, a sigma-1 receptor ligand 27
New thienopyrimidine and quinazoline derivatives as potential 5-HT7 receptor ligands. 26
Novel selective ligands for the serotonergic 5-HT7 receptor: tricyclic derivatives Bearing the pyrimido-4(3H)-one ring 26
Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT1A and 5-HT7 receptor ligands 26
Strategies to improve resveratrol systemic and topical bioavailability: An update 25
New homo and hetero bis-arylpiperazine and bis-benzylpiperazine derivatives as 5-HT7R selective ligands: design and synthesis 24
Discovery of 3-(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligands 21
Laboratory-Scale Semipreparative Enantioresolution of Phenylethanolic-Azole Heme Oxygenase-1 Inhibitors 20
New 5-Ht7 Receptor Ligands As Potential Antidepressant Agents. 18
New alkylpiperazines as 5-HT7R ligands 17
Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain 15
Thieno[3,2-d]pyrimidine as a scaffold for 5-HT7 receptor ligands 15
UPLC-MS/MS method for the quantification of MCI-77, a novel sigma-1 receptor ligand, and its application to pharmacokinetic studies 14
In vitro and in silico analysis of imatinib analogues as anti- Trypanosoma cruzi drug candidates 12
Novel benzothiazolones and benzoxazolones-based σ receptor ligands: synthesis and preliminary pharmacological evaluation against allodynia 11
New alkylpiperazines as 5-HT7R ligands 4
The Inhibition of Neuropathic Pain Incited by Nerve Injury and Accompanying Mood Disorders by New Heme Oxygenase-1 Inducers: Mechanisms Implicated 3
Correction to Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 3
Totale 2.216
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Categoria #
all - tutte 7.538
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 7.538
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20197 0 0 0 0 0 0 0 0 0 0 1 6
2019/2020246 47 28 22 9 26 10 22 2 8 39 14 19
2020/2021204 6 9 41 12 54 6 14 4 6 10 23 19
2021/2022507 36 57 59 16 67 17 69 33 17 27 11 98
2022/2023857 69 74 38 116 67 126 3 141 147 15 52 9
2023/2024325 20 52 21 22 48 110 5 28 1 18 0 0
Totale 2.216