IRIS
INTAGLIATA, SEBASTIANO
 Distribuzione geografica
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Continente #
NA - Nord America 1.664
EU - Europa 1.265
AS - Asia 623
SA - Sud America 195
AF - Africa 136
OC - Oceania 2
Totale 3.885
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Nazione #
US - Stati Uniti d'America 1.634
IT - Italia 797
SG - Singapore 370
IE - Irlanda 191
BR - Brasile 182
CN - Cina 169
CI - Costa d'Avorio 78
DE - Germania 66
SN - Senegal 47
RU - Federazione Russa 45
UA - Ucraina 31
CA - Canada 23
FR - Francia 23
FI - Finlandia 20
VN - Vietnam 18
GB - Regno Unito 17
ES - Italia 14
KR - Corea 13
PL - Polonia 13
CZ - Repubblica Ceca 12
IN - India 12
BD - Bangladesh 6
CH - Svizzera 6
TR - Turchia 6
AR - Argentina 5
IQ - Iraq 5
NL - Olanda 5
AT - Austria 4
SE - Svezia 4
VE - Venezuela 4
GR - Grecia 3
HK - Hong Kong 3
JP - Giappone 3
KE - Kenya 3
RO - Romania 3
UZ - Uzbekistan 3
AL - Albania 2
AU - Australia 2
AZ - Azerbaigian 2
CM - Camerun 2
DO - Repubblica Dominicana 2
GT - Guatemala 2
KG - Kirghizistan 2
LT - Lituania 2
LU - Lussemburgo 2
MA - Marocco 2
MX - Messico 2
NG - Nigeria 2
OM - Oman 2
AE - Emirati Arabi Uniti 1
BE - Belgio 1
BG - Bulgaria 1
BY - Bielorussia 1
CL - Cile 1
CO - Colombia 1
EG - Egitto 1
GY - Guiana 1
HU - Ungheria 1
IR - Iran 1
JM - Giamaica 1
JO - Giordania 1
KZ - Kazakistan 1
LB - Libano 1
MT - Malta 1
NP - Nepal 1
PE - Perù 1
PK - Pakistan 1
PS - Palestinian Territory 1
TW - Taiwan 1
ZA - Sudafrica 1
Totale 3.885
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Città #
Santa Clara 277
Chandler 276
Singapore 213
Catania 197
Dublin 187
Chicago 174
Boardman 84
Abidjan 78
Ashburn 70
Houston 66
Cambridge 51
Lawrence 48
Dakar 47
Andover 46
Redmond 38
Naples 36
Rome 35
Civitanova Marche 34
Jacksonville 30
Munich 26
Hefei 25
São Paulo 25
Beijing 24
Des Moines 22
Wilmington 22
Nanjing 21
Palermo 21
Boydton 18
The Dalles 18
Bremen 17
Columbus 17
Milan 17
Dong Ket 15
Messina 15
Toronto 14
Council Bluffs 12
Seoul 12
Turku 12
Seattle 11
Salerno 10
Civitavecchia 9
Pozzallo 9
Viagrande 9
Hebei 8
Los Angeles 8
Aci Catena 7
Brno 7
Gela 7
New York 7
Ottawa 7
Saint Petersburg 7
Siracusa 7
Turin 7
Warsaw 7
Barcelona 6
Ferrara di Monte Baldo 6
Foggia 6
Fortaleza 6
Garbagnate Milanese 6
Goiânia 6
London 6
Moscow 6
Washington 6
Fairfield 5
Gravina di Catania 5
Nanchang 5
Padova 5
Raffadali 5
Reggio Calabria 5
San Francisco 5
Santa Maria di Licodia 5
Shenyang 5
Brasília 4
Brooklyn 4
Florence 4
Helsinki 4
Lappeenranta 4
Madrid 4
Milazzo 4
Misterbianco 4
Ribeirão Preto 4
Sumaré 4
Tremestieri Etneo 4
Vicenza 4
Bucharest 3
Changsha 3
Dallas 3
Dhaka 3
Ferrara 3
Gunzenhausen 3
Latina 3
Lucca 3
Maceió 3
Marseille 3
Mascalucia 3
Modica 3
New Haven 3
Norwalk 3
Novara 3
Olomouc 3
Totale 2.662
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Nome #
Design, synthesis, and pharmacological evaluation of NO donor-sigma receptors hybrids for the treatment of cancer 127
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 123
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 110
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 107
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 107
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 96
Solid lipid nanoparticles loading idebenone ester with pyroglutamic acid: In vitro antioxidant activity and in vivo topical efficacy 94
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 93
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 90
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 87
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 87
New arylethanolimidazole derivatives as HO-1 inhibitors with cytotoxicity against MCF-7 breast cancer cells 85
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 82
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 79
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 78
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 76
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 76
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 75
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 74
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 74
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 73
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 73
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 72
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 70
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 69
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 68
Ginseng and heme oxygenase-1: The link between an old herb and a new protective system 68
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells 67
Novel mutual prodrug of 5-fluorouracil and heme oxygenase-1 inhibitor (5-FU/HO-1 hybrid): design and preliminary in vitro evaluation 66
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 66
Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In Vivo 66
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 64
In vitro antioxidant and anti-glycation activity of resveratrol and its novel triester with trolox 62
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 61
Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats 61
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 60
Benzimidazolone-based selective σ2 receptor ligands: Synthesis and pharmacological evaluation 60
The analgesic potential of glycosides derived from medicinal plants 60
Divergent cytotoxic and metabolically stimulative functions of sigma-2 receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives 59
Characterization of sigma 1 receptor antagonist CM-304 and its analog, AZ-66: Novel therapeutics against allodynia and induced pain 58
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 57
Bioanalytical method development and pharmacokinetics of MCI-92, a sigma-1 receptor ligand 53
Exploring 1-adamantanamine as an alternative amine moiety for metabolically labile azepane ring in newly synthesized benzo[d]thiazol-2(3H)one σ receptor ligands 52
Combination of heme oxygenase-1 inhibitors and temozolomide to improve the anticancer effect in glioblastoma 50
Discovery of 3-(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligands 49
Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain 48
Strategies to improve resveratrol systemic and topical bioavailability: An update 45
Novel selective ligands for the serotonergic 5-HT7 receptor: tricyclic derivatives Bearing the pyrimido-4(3H)-one ring 44
New homo and hetero bis-arylpiperazine and bis-benzylpiperazine derivatives as 5-HT7R selective ligands: design and synthesis 44
Correction to Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 41
New thienopyrimidine and quinazoline derivatives as potential 5-HT7 receptor ligands. 41
Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT1A and 5-HT7 receptor ligands 39
Synthesis and in Vitro Evaluation of CAPE Derivatives as Ferroptosis Inducers in Triple Negative Breast Cancer 36
In vitro and in silico analysis of imatinib analogues as anti- Trypanosoma cruzi drug candidates 35
New 5-Ht7 Receptor Ligands As Potential Antidepressant Agents. 34
UPLC-MS/MS method for the quantification of MCI-77, a novel sigma-1 receptor ligand, and its application to pharmacokinetic studies 33
Laboratory-Scale Semipreparative Enantioresolution of Phenylethanolic-Azole Heme Oxygenase-1 Inhibitors 32
New alkylpiperazines as 5-HT7R ligands 31
Lauric acid-based thermosensitive delivery system for the treatment of head and neck squamous cell carcinoma 30
The Inhibition of Neuropathic Pain Incited by Nerve Injury and Accompanying Mood Disorders by New Heme Oxygenase-1 Inducers: Mechanisms Implicated 30
Thieno[3,2-d]pyrimidine as a scaffold for 5-HT7 receptor ligands 30
Novel benzothiazolones and benzoxazolones-based σ receptor ligands: synthesis and preliminary pharmacological evaluation against allodynia 27
New alkylpiperazines as 5-HT7R ligands 25
Totale 4.029
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Categoria #
all - tutte 15.304
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 15.304
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021204 6 9 41 12 54 6 14 4 6 10 23 19
2021/2022507 36 57 59 16 67 17 69 33 17 27 11 98
2022/2023857 69 74 38 116 67 126 3 141 147 15 52 9
2023/2024439 20 52 21 22 48 110 5 28 1 18 65 49
2024/20251.659 24 255 67 134 294 150 168 51 126 144 138 108
2025/202640 40 0 0 0 0 0 0 0 0 0 0 0
Totale 4.029