IRIS
INTAGLIATA, SEBASTIANO
 Distribuzione geografica
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Continente #
NA - Nord America 1.471
EU - Europa 1.056
AS - Asia 337
AF - Africa 130
SA - Sud America 15
OC - Oceania 2
Totale 3.011
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Nazione #
US - Stati Uniti d'America 1.449
IT - Italia 648
IE - Irlanda 191
SG - Singapore 187
CN - Cina 115
CI - Costa d'Avorio 78
DE - Germania 57
SN - Senegal 47
RU - Federazione Russa 43
UA - Ucraina 29
CA - Canada 22
FR - Francia 20
VN - Vietnam 17
BR - Brasile 14
GB - Regno Unito 13
CZ - Repubblica Ceca 9
FI - Finlandia 7
IN - India 7
CH - Svizzera 6
ES - Italia 6
PL - Polonia 6
NL - Olanda 5
GR - Grecia 3
JP - Giappone 3
RO - Romania 3
SE - Svezia 3
AU - Australia 2
CM - Camerun 2
HK - Hong Kong 2
LU - Lussemburgo 2
NG - Nigeria 2
AT - Austria 1
BE - Belgio 1
BG - Bulgaria 1
BY - Bielorussia 1
CL - Cile 1
EG - Egitto 1
HU - Ungheria 1
IQ - Iraq 1
IR - Iran 1
KR - Corea 1
LB - Libano 1
TR - Turchia 1
TW - Taiwan 1
Totale 3.011
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Città #
Chandler 276
Santa Clara 199
Dublin 187
Chicago 173
Catania 157
Singapore 129
Boardman 84
Abidjan 78
Ashburn 68
Houston 66
Cambridge 51
Lawrence 48
Dakar 47
Andover 46
Redmond 38
Civitanova Marche 34
Jacksonville 30
Rome 24
Des Moines 22
Wilmington 22
Nanjing 21
Palermo 20
Munich 19
Boydton 18
Bremen 17
Dong Ket 15
Milan 15
Toronto 14
Beijing 11
Seattle 11
Civitavecchia 9
Messina 9
Hebei 8
Brno 7
Gela 7
Ottawa 7
Saint Petersburg 7
Siracusa 7
Ferrara di Monte Baldo 6
Foggia 6
Moscow 6
Turin 6
Fairfield 5
Gravina di Catania 5
Nanchang 5
Padova 5
Raffadali 5
Reggio Calabria 5
Santa Maria di Licodia 5
Shenyang 5
Florence 4
Helsinki 4
Los Angeles 4
Madrid 4
Milazzo 4
Misterbianco 4
São Paulo 4
Vicenza 4
Washington 4
Bucharest 3
Changsha 3
Ferrara 3
Gunzenhausen 3
Lappeenranta 3
Latina 3
London 3
Lucca 3
Mascalucia 3
Modica 3
New Haven 3
Norwalk 3
Novara 3
Paris 3
Pune 3
Rimini 3
Roccalumera 3
San Mateo 3
Tokyo 3
Tremestieri Etneo 3
Villamagna 3
Abuja 2
Amsterdam 2
Cagliari 2
Cergy 2
Dallas 2
Esslingen am Neckar 2
Floridia 2
Froges 2
Giardini-Naxos 2
Hanoi 2
Jiaxing 2
Jinan 2
Jinzhong 2
Kraków 2
Manduria 2
Mumbai 2
Naples 2
New Orleans 2
New York 2
Phoenix 2
Totale 2.204
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Nome #
Design, synthesis, and pharmacological evaluation of NO donor-sigma receptors hybrids for the treatment of cancer 111
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 95
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 91
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 89
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 82
Solid lipid nanoparticles loading idebenone ester with pyroglutamic acid: In vitro antioxidant activity and in vivo topical efficacy 82
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 79
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 74
New arylethanolimidazole derivatives as HO-1 inhibitors with cytotoxicity against MCF-7 breast cancer cells 74
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 72
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 71
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 71
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 70
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 68
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 67
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 63
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 63
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 63
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 59
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 59
Novel mutual prodrug of 5-fluorouracil and heme oxygenase-1 inhibitor (5-FU/HO-1 hybrid): design and preliminary in vitro evaluation 57
Ginseng and heme oxygenase-1: The link between an old herb and a new protective system 57
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 57
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 56
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 55
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 55
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 54
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 54
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 54
The analgesic potential of glycosides derived from medicinal plants 52
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 51
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 51
Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats 51
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 51
In vitro antioxidant and anti-glycation activity of resveratrol and its novel triester with trolox 46
Divergent cytotoxic and metabolically stimulative functions of sigma-2 receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives 44
Characterization of sigma 1 receptor antagonist CM-304 and its analog, AZ-66: Novel therapeutics against allodynia and induced pain 44
Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In Vivo 44
Exploring 1-adamantanamine as an alternative amine moiety for metabolically labile azepane ring in newly synthesized benzo[d]thiazol-2(3H)one σ receptor ligands 44
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 43
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells 42
Bioanalytical method development and pharmacokinetics of MCI-92, a sigma-1 receptor ligand 40
Benzimidazolone-based selective σ2 receptor ligands: Synthesis and pharmacological evaluation 39
Discovery of 3-(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligands 37
Novel selective ligands for the serotonergic 5-HT7 receptor: tricyclic derivatives Bearing the pyrimido-4(3H)-one ring 36
Strategies to improve resveratrol systemic and topical bioavailability: An update 36
New thienopyrimidine and quinazoline derivatives as potential 5-HT7 receptor ligands. 34
Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT1A and 5-HT7 receptor ligands 33
New homo and hetero bis-arylpiperazine and bis-benzylpiperazine derivatives as 5-HT7R selective ligands: design and synthesis 32
Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain 28
Laboratory-Scale Semipreparative Enantioresolution of Phenylethanolic-Azole Heme Oxygenase-1 Inhibitors 28
New alkylpiperazines as 5-HT7R ligands 25
New 5-Ht7 Receptor Ligands As Potential Antidepressant Agents. 25
Correction to Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 23
Thieno[3,2-d]pyrimidine as a scaffold for 5-HT7 receptor ligands 22
UPLC-MS/MS method for the quantification of MCI-77, a novel sigma-1 receptor ligand, and its application to pharmacokinetic studies 22
Synthesis and in Vitro Evaluation of CAPE Derivatives as Ferroptosis Inducers in Triple Negative Breast Cancer 21
In vitro and in silico analysis of imatinib analogues as anti- Trypanosoma cruzi drug candidates 20
Novel benzothiazolones and benzoxazolones-based σ receptor ligands: synthesis and preliminary pharmacological evaluation against allodynia 20
The Inhibition of Neuropathic Pain Incited by Nerve Injury and Accompanying Mood Disorders by New Heme Oxygenase-1 Inducers: Mechanisms Implicated 14
Combination of heme oxygenase-1 inhibitors and temozolomide to improve the anticancer effect in glioblastoma 14
New alkylpiperazines as 5-HT7R ligands 12
Lauric acid-based thermosensitive delivery system for the treatment of head and neck squamous cell carcinoma 12
Totale 3.138
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Categoria #
all - tutte 11.488
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 11.488
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020114 0 0 0 0 0 10 22 2 8 39 14 19
2020/2021204 6 9 41 12 54 6 14 4 6 10 23 19
2021/2022507 36 57 59 16 67 17 69 33 17 27 11 98
2022/2023857 69 74 38 116 67 126 3 141 147 15 52 9
2023/2024439 20 52 21 22 48 110 5 28 1 18 65 49
2024/2025808 24 255 67 134 294 34 0 0 0 0 0 0
Totale 3.138