IRIS
INTAGLIATA, SEBASTIANO
 Distribuzione geografica
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Continente #
NA - Nord America 1.728
EU - Europa 1.287
AS - Asia 826
SA - Sud America 207
AF - Africa 136
OC - Oceania 2
Totale 4.186
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Nazione #
US - Stati Uniti d'America 1.693
IT - Italia 802
SG - Singapore 426
CN - Cina 279
BR - Brasile 192
IE - Irlanda 191
CI - Costa d'Avorio 78
DE - Germania 69
SN - Senegal 47
RU - Federazione Russa 45
KR - Corea 37
UA - Ucraina 31
CA - Canada 27
FR - Francia 24
GB - Regno Unito 22
FI - Finlandia 20
VN - Vietnam 18
PL - Polonia 16
ES - Italia 15
CZ - Repubblica Ceca 12
IN - India 12
BD - Bangladesh 10
IQ - Iraq 8
TR - Turchia 7
CH - Svizzera 6
JP - Giappone 6
AR - Argentina 5
NL - Olanda 5
SE - Svezia 5
VE - Venezuela 5
AT - Austria 4
DO - Repubblica Dominicana 3
GR - Grecia 3
HK - Hong Kong 3
KE - Kenya 3
LT - Lituania 3
RO - Romania 3
UZ - Uzbekistan 3
AL - Albania 2
AU - Australia 2
AZ - Azerbaigian 2
BG - Bulgaria 2
BY - Bielorussia 2
CM - Camerun 2
GT - Guatemala 2
GY - Guiana 2
JO - Giordania 2
KG - Kirghizistan 2
LU - Lussemburgo 2
MA - Marocco 2
MX - Messico 2
NG - Nigeria 2
OM - Oman 2
AE - Emirati Arabi Uniti 1
BE - Belgio 1
CL - Cile 1
CO - Colombia 1
EG - Egitto 1
HU - Ungheria 1
IL - Israele 1
IR - Iran 1
JM - Giamaica 1
KZ - Kazakistan 1
LB - Libano 1
MT - Malta 1
NP - Nepal 1
PE - Perù 1
PK - Pakistan 1
PS - Palestinian Territory 1
TW - Taiwan 1
ZA - Sudafrica 1
Totale 4.186
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Città #
Santa Clara 281
Chandler 276
Singapore 257
Catania 200
Dublin 187
Chicago 177
Boardman 84
Ashburn 82
Abidjan 78
Beijing 75
Hefei 74
Houston 66
Cambridge 51
Lawrence 48
Dakar 47
Andover 46
Redmond 38
Naples 36
Seoul 36
Rome 35
Civitanova Marche 34
Jacksonville 30
São Paulo 28
Munich 26
Des Moines 22
Wilmington 22
Nanjing 21
Palermo 21
Milan 19
Boydton 18
The Dalles 18
Bremen 17
Columbus 17
Los Angeles 17
Dong Ket 15
Messina 15
Council Bluffs 14
Toronto 14
Seattle 12
Turku 12
Salerno 10
Warsaw 10
Civitavecchia 9
New York 9
Pozzallo 9
Viagrande 9
Dallas 8
Hebei 8
Aci Catena 7
Brno 7
Gela 7
Ottawa 7
Saint Petersburg 7
San Francisco 7
Siracusa 7
Turin 7
Barcelona 6
Brooklyn 6
Ferrara di Monte Baldo 6
Foggia 6
Fortaleza 6
Garbagnate Milanese 6
Goiânia 6
London 6
Moscow 6
Tokyo 6
Washington 6
Baghdad 5
Fairfield 5
Gravina di Catania 5
Nanchang 5
Padova 5
Raffadali 5
Reggio Calabria 5
Santa Maria di Licodia 5
Shenyang 5
Brasília 4
Florence 4
Helsinki 4
Lappeenranta 4
Madrid 4
Milazzo 4
Misterbianco 4
Ribeirão Preto 4
Sumaré 4
Tremestieri Etneo 4
Vicenza 4
Boston 3
Bucharest 3
Canoas 3
Changsha 3
Curitiba 3
Dhaka 3
Ferrara 3
Georgetown 3
Gunzenhausen 3
Latina 3
Lucca 3
Maceió 3
Marseille 3
Totale 2.888
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Nome #
Design, synthesis, and pharmacological evaluation of NO donor-sigma receptors hybrids for the treatment of cancer 130
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 126
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 121
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 112
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 110
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 102
Solid lipid nanoparticles loading idebenone ester with pyroglutamic acid: In vitro antioxidant activity and in vivo topical efficacy 97
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 97
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 94
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 92
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 89
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 89
New arylethanolimidazole derivatives as HO-1 inhibitors with cytotoxicity against MCF-7 breast cancer cells 88
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 86
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 81
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 80
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 79
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 79
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 78
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 77
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 77
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells 76
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 76
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 73
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 72
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 72
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 71
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 70
Ginseng and heme oxygenase-1: The link between an old herb and a new protective system 70
Combination of heme oxygenase-1 inhibitors and temozolomide to improve the anticancer effect in glioblastoma 68
Novel mutual prodrug of 5-fluorouracil and heme oxygenase-1 inhibitor (5-FU/HO-1 hybrid): design and preliminary in vitro evaluation 68
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 68
Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In Vivo 68
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 67
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 67
In vitro antioxidant and anti-glycation activity of resveratrol and its novel triester with trolox 66
Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats 64
Benzimidazolone-based selective σ2 receptor ligands: Synthesis and pharmacological evaluation 64
The analgesic potential of glycosides derived from medicinal plants 64
Divergent cytotoxic and metabolically stimulative functions of sigma-2 receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives 63
Characterization of sigma 1 receptor antagonist CM-304 and its analog, AZ-66: Novel therapeutics against allodynia and induced pain 63
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 62
Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain 57
Bioanalytical method development and pharmacokinetics of MCI-92, a sigma-1 receptor ligand 57
Exploring 1-adamantanamine as an alternative amine moiety for metabolically labile azepane ring in newly synthesized benzo[d]thiazol-2(3H)one σ receptor ligands 55
Correction to Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 52
Discovery of 3-(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligands 52
In vitro and in silico analysis of imatinib analogues as anti- Trypanosoma cruzi drug candidates 48
Synthesis and in Vitro Evaluation of CAPE Derivatives as Ferroptosis Inducers in Triple Negative Breast Cancer 47
Strategies to improve resveratrol systemic and topical bioavailability: An update 47
New homo and hetero bis-arylpiperazine and bis-benzylpiperazine derivatives as 5-HT7R selective ligands: design and synthesis 46
Novel selective ligands for the serotonergic 5-HT7 receptor: tricyclic derivatives Bearing the pyrimido-4(3H)-one ring 45
Lauric acid-based thermosensitive delivery system for the treatment of head and neck squamous cell carcinoma 43
The Inhibition of Neuropathic Pain Incited by Nerve Injury and Accompanying Mood Disorders by New Heme Oxygenase-1 Inducers: Mechanisms Implicated 43
New thienopyrimidine and quinazoline derivatives as potential 5-HT7 receptor ligands. 43
Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT1A and 5-HT7 receptor ligands 42
New alkylpiperazines as 5-HT7R ligands 38
New 5-Ht7 Receptor Ligands As Potential Antidepressant Agents. 37
UPLC-MS/MS method for the quantification of MCI-77, a novel sigma-1 receptor ligand, and its application to pharmacokinetic studies 35
New alkylpiperazines as 5-HT7R ligands 33
Laboratory-Scale Semipreparative Enantioresolution of Phenylethanolic-Azole Heme Oxygenase-1 Inhibitors 33
Thieno[3,2-d]pyrimidine as a scaffold for 5-HT7 receptor ligands 32
Novel benzothiazolones and benzoxazolones-based σ receptor ligands: synthesis and preliminary pharmacological evaluation against allodynia 29
Totale 4.330
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Categoria #
all - tutte 16.378
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 16.378
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021198 0 9 41 12 54 6 14 4 6 10 23 19
2021/2022507 36 57 59 16 67 17 69 33 17 27 11 98
2022/2023857 69 74 38 116 67 126 3 141 147 15 52 9
2023/2024439 20 52 21 22 48 110 5 28 1 18 65 49
2024/20251.659 24 255 67 134 294 150 168 51 126 144 138 108
2025/2026341 216 125 0 0 0 0 0 0 0 0 0 0
Totale 4.330