IRIS
INTAGLIATA, SEBASTIANO
 Distribuzione geografica
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Continente #
NA - Nord America 2.402
EU - Europa 1.318
AS - Asia 918
SA - Sud America 257
AF - Africa 164
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5.062
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Nazione #
US - Stati Uniti d'America 2.363
IT - Italia 819
SG - Singapore 431
CN - Cina 319
BR - Brasile 231
IE - Irlanda 193
CI - Costa d'Avorio 101
DE - Germania 69
SN - Senegal 47
RU - Federazione Russa 46
KR - Corea 40
UA - Ucraina 34
VN - Vietnam 34
CA - Canada 28
FR - Francia 25
FI - Finlandia 23
GB - Regno Unito 23
JP - Giappone 18
ES - Italia 16
PL - Polonia 16
IN - India 14
CZ - Repubblica Ceca 12
BD - Bangladesh 11
IQ - Iraq 10
AR - Argentina 9
HK - Hong Kong 7
TR - Turchia 7
CH - Svizzera 6
NL - Olanda 6
SE - Svezia 6
ID - Indonesia 5
MX - Messico 5
VE - Venezuela 5
AT - Austria 4
EC - Ecuador 4
EG - Egitto 4
UZ - Uzbekistan 4
DO - Repubblica Dominicana 3
GR - Grecia 3
KE - Kenya 3
LT - Lituania 3
RO - Romania 3
ZA - Sudafrica 3
AL - Albania 2
AU - Australia 2
AZ - Azerbaigian 2
BG - Bulgaria 2
BY - Bielorussia 2
CL - Cile 2
CM - Camerun 2
CO - Colombia 2
GT - Guatemala 2
GY - Guiana 2
JO - Giordania 2
KG - Kirghizistan 2
LU - Lussemburgo 2
MA - Marocco 2
NG - Nigeria 2
OM - Oman 2
AE - Emirati Arabi Uniti 1
BE - Belgio 1
HU - Ungheria 1
IL - Israele 1
IR - Iran 1
JM - Giamaica 1
KZ - Kazakistan 1
LB - Libano 1
MT - Malta 1
NP - Nepal 1
PE - Perù 1
PK - Pakistan 1
PS - Palestinian Territory 1
PY - Paraguay 1
SA - Arabia Saudita 1
TW - Taiwan 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 5.062
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Città #
Dallas 634
Santa Clara 284
Chandler 276
Singapore 259
Catania 204
Dublin 189
Chicago 177
Abidjan 101
Ashburn 97
Beijing 86
Boardman 84
Hefei 79
Houston 67
Cambridge 51
Lawrence 48
Dakar 47
Andover 46
Seoul 39
Redmond 38
Naples 37
Rome 35
Civitanova Marche 34
São Paulo 31
Jacksonville 30
Munich 26
Des Moines 22
Wilmington 22
Nanjing 21
Palermo 21
Milan 20
Boydton 18
Los Angeles 18
The Dalles 18
Tokyo 18
Bremen 17
Columbus 17
Dong Ket 15
Messina 15
Council Bluffs 14
Toronto 14
Seattle 12
Turku 12
New York 11
Salerno 10
Warsaw 10
Civitavecchia 9
Pozzallo 9
Viagrande 9
Gravina di Catania 8
Hebei 8
Aci Catena 7
Brno 7
Brooklyn 7
Gela 7
Ho Chi Minh City 7
Lappeenranta 7
Ottawa 7
Saint Petersburg 7
San Francisco 7
Siracusa 7
Turin 7
Baghdad 6
Barcelona 6
Ferrara di Monte Baldo 6
Foggia 6
Fortaleza 6
Garbagnate Milanese 6
Goiânia 6
London 6
Moscow 6
Washington 6
Brasília 5
Curitiba 5
Fairfield 5
Hanoi 5
Hong Kong 5
Jakarta 5
Nanchang 5
Padova 5
Raffadali 5
Reggio Calabria 5
Santa Maria di Licodia 5
Shenyang 5
Tremestieri Etneo 5
Florence 4
Helsinki 4
Maceió 4
Madrid 4
Milazzo 4
Misterbianco 4
Ribeirão Preto 4
Stockholm 4
Sumaré 4
Tashkent 4
Vicenza 4
Atlanta 3
Boston 3
Bucharest 3
Canoas 3
Changsha 3
Totale 3.628
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Nome #
Haloperidol drug repurposing unveils ferroptosis involvement in breast cancer cells 219
Design, synthesis, and pharmacological evaluation of NO donor-sigma receptors hybrids for the treatment of cancer 143
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 140
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 138
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 134
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 125
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 109
Solid lipid nanoparticles loading idebenone ester with pyroglutamic acid: In vitro antioxidant activity and in vivo topical efficacy 108
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 108
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 107
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 102
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 102
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 99
New arylethanolimidazole derivatives as HO-1 inhibitors with cytotoxicity against MCF-7 breast cancer cells 99
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 98
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells 97
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 96
Combination of heme oxygenase-1 inhibitors and temozolomide to improve the anticancer effect in glioblastoma 92
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 91
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 90
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 88
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 87
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 87
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 87
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 86
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 85
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 83
In vitro antioxidant and anti-glycation activity of resveratrol and its novel triester with trolox 82
Ginseng and heme oxygenase-1: The link between an old herb and a new protective system 81
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 80
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 79
Novel mutual prodrug of 5-fluorouracil and heme oxygenase-1 inhibitor (5-FU/HO-1 hybrid): design and preliminary in vitro evaluation 78
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 78
Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In Vivo 78
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 77
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 77
The analgesic potential of glycosides derived from medicinal plants 76
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 75
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 74
Characterization of sigma 1 receptor antagonist CM-304 and its analog, AZ-66: Novel therapeutics against allodynia and induced pain 74
Correction to Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 73
Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats 72
Benzimidazolone-based selective σ2 receptor ligands: Synthesis and pharmacological evaluation 67
Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain 66
Divergent cytotoxic and metabolically stimulative functions of sigma-2 receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives 65
Bioanalytical method development and pharmacokinetics of MCI-92, a sigma-1 receptor ligand 64
Discovery of 3-(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligands 62
Exploring 1-adamantanamine as an alternative amine moiety for metabolically labile azepane ring in newly synthesized benzo[d]thiazol-2(3H)one σ receptor ligands 60
Synthesis and in Vitro Evaluation of CAPE Derivatives as Ferroptosis Inducers in Triple Negative Breast Cancer 56
Strategies to improve resveratrol systemic and topical bioavailability: An update 56
In vitro and in silico analysis of imatinib analogues as anti- Trypanosoma cruzi drug candidates 55
Lauric acid-based thermosensitive delivery system for the treatment of head and neck squamous cell carcinoma 53
New thienopyrimidine and quinazoline derivatives as potential 5-HT7 receptor ligands. 53
The Inhibition of Neuropathic Pain Incited by Nerve Injury and Accompanying Mood Disorders by New Heme Oxygenase-1 Inducers: Mechanisms Implicated 51
New alkylpiperazines as 5-HT7R ligands 49
Novel selective ligands for the serotonergic 5-HT7 receptor: tricyclic derivatives Bearing the pyrimido-4(3H)-one ring 49
New 5-Ht7 Receptor Ligands As Potential Antidepressant Agents. 49
New homo and hetero bis-arylpiperazine and bis-benzylpiperazine derivatives as 5-HT7R selective ligands: design and synthesis 47
New alkylpiperazines as 5-HT7R ligands 46
Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT1A and 5-HT7 receptor ligands 46
Thieno[3,2-d]pyrimidine as a scaffold for 5-HT7 receptor ligands 44
UPLC-MS/MS method for the quantification of MCI-77, a novel sigma-1 receptor ligand, and its application to pharmacokinetic studies 43
Laboratory-Scale Semipreparative Enantioresolution of Phenylethanolic-Azole Heme Oxygenase-1 Inhibitors 38
Novel benzothiazolones and benzoxazolones-based σ receptor ligands: synthesis and preliminary pharmacological evaluation against allodynia 34
Totale 5.207
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Categoria #
all - tutte 18.383
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 18.383
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021148 0 0 0 12 54 6 14 4 6 10 23 19
2021/2022507 36 57 59 16 67 17 69 33 17 27 11 98
2022/2023857 69 74 38 116 67 126 3 141 147 15 52 9
2023/2024439 20 52 21 22 48 110 5 28 1 18 65 49
2024/20251.659 24 255 67 134 294 150 168 51 126 144 138 108
2025/20261.218 216 150 733 119 0 0 0 0 0 0 0 0
Totale 5.207