IRIS
INTAGLIATA, SEBASTIANO
 Distribuzione geografica
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Continente #
NA - Nord America 3.074
EU - Europa 2.128
AS - Asia 1.587
SA - Sud America 317
AF - Africa 232
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 1
Totale 7.343
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Nazione #
US - Stati Uniti d'America 3.000
IT - Italia 887
SG - Singapore 789
RU - Federazione Russa 640
CN - Cina 419
BR - Brasile 277
IE - Irlanda 196
VN - Vietnam 120
CI - Costa d'Avorio 102
FR - Francia 91
DE - Germania 78
KR - Corea 61
SN - Senegal 48
GB - Regno Unito 43
CA - Canada 42
UA - Ucraina 39
IN - India 35
NG - Nigeria 32
FI - Finlandia 28
BD - Bangladesh 24
JP - Giappone 24
IQ - Iraq 23
ES - Italia 22
MX - Messico 21
PL - Polonia 20
HK - Hong Kong 19
NL - Olanda 15
TR - Turchia 15
CZ - Repubblica Ceca 14
ZA - Sudafrica 14
AR - Argentina 13
SE - Svezia 13
KE - Kenya 10
EG - Egitto 8
PK - Pakistan 8
ID - Indonesia 7
LT - Lituania 7
BJ - Benin 6
CH - Svizzera 6
EC - Ecuador 6
UZ - Uzbekistan 6
AT - Austria 5
CL - Cile 5
CO - Colombia 5
GR - Grecia 5
VE - Venezuela 5
AU - Australia 4
AZ - Azerbaigian 4
IR - Iran 4
JO - Giordania 4
SA - Arabia Saudita 4
AE - Emirati Arabi Uniti 3
DO - Repubblica Dominicana 3
GT - Guatemala 3
JM - Giamaica 3
MA - Marocco 3
OM - Oman 3
RO - Romania 3
AL - Albania 2
BG - Bulgaria 2
BY - Bielorussia 2
CM - Camerun 2
ET - Etiopia 2
GY - Guiana 2
HU - Ungheria 2
IL - Israele 2
KG - Kirghizistan 2
LB - Libano 2
LU - Lussemburgo 2
MT - Malta 2
NP - Nepal 2
PH - Filippine 2
PY - Paraguay 2
TN - Tunisia 2
BE - Belgio 1
BO - Bolivia 1
BZ - Belize 1
CG - Congo 1
DM - Dominica 1
GA - Gabon 1
GH - Ghana 1
KZ - Kazakistan 1
LV - Lettonia 1
MY - Malesia 1
PE - Perù 1
PS - Palestinian Territory 1
PT - Portogallo 1
RS - Serbia 1
SY - Repubblica araba siriana 1
TW - Taiwan 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 7.343
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Città #
Dallas 637
Singapore 483
Moscow 296
Santa Clara 295
Chandler 276
San Jose 235
Catania 206
Dublin 192
Chicago 182
Ashburn 175
Beijing 108
Abidjan 102
Boardman 84
Hefei 79
Houston 69
Seoul 60
Los Angeles 59
Lauterbourg 58
Cambridge 51
Lawrence 49
Dakar 48
Andover 46
Rome 45
São Paulo 41
Naples 39
Ho Chi Minh City 38
Redmond 38
Palermo 37
Council Bluffs 36
Civitanova Marche 34
Jacksonville 31
New York 30
Hanoi 27
Munich 26
Tokyo 24
Buffalo 22
Des Moines 22
Milan 22
Nanjing 22
Wilmington 22
Boydton 18
The Dalles 18
Bremen 17
Columbus 17
Dong Ket 15
Lagos 15
Messina 15
Orem 15
Hong Kong 14
Toronto 14
Warsaw 14
Denver 13
Seattle 13
Baghdad 12
Montreal 12
Turku 12
Atlanta 11
London 11
Stockholm 11
Salerno 10
Abuja 9
Amsterdam 9
Civitavecchia 9
Florence 9
Mexico City 9
Poplar 9
Pozzallo 9
Viagrande 9
Brooklyn 8
Da Nang 8
Frankfurt am Main 8
Gravina di Catania 8
Hebei 8
Helsinki 8
Johannesburg 8
Lappeenranta 8
Port Harcourt 8
San Francisco 8
Aci Catena 7
Brno 7
Chennai 7
Fortaleza 7
Gela 7
Goiânia 7
Ottawa 7
Phoenix 7
Saint Petersburg 7
Siracusa 7
Turin 7
Barcelona 6
Cotonou 6
Ferrara di Monte Baldo 6
Foggia 6
Garbagnate Milanese 6
Mumbai 6
Reggio Calabria 6
Tashkent 6
Washington 6
Boston 5
Brasília 5
Totale 4.916
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Nome #
Haloperidol drug repurposing unveils ferroptosis involvement in breast cancer cells 294
Design, synthesis, and pharmacological evaluation of NO donor-sigma receptors hybrids for the treatment of cancer 199
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 192
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 188
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 186
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 186
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 155
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 151
Solid lipid nanoparticles loading idebenone ester with pyroglutamic acid: In vitro antioxidant activity and in vivo topical efficacy 148
Combination of heme oxygenase-1 inhibitors and temozolomide to improve the anticancer effect in glioblastoma 145
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 143
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells 138
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 137
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 137
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 136
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 135
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 133
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 132
New arylethanolimidazole derivatives as HO-1 inhibitors with cytotoxicity against MCF-7 breast cancer cells 132
Correction to Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 128
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 128
Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In Vivo 127
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 124
Ginseng and heme oxygenase-1: The link between an old herb and a new protective system 124
Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain 122
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 120
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 120
In vitro antioxidant and anti-glycation activity of resveratrol and its novel triester with trolox 120
The analgesic potential of glycosides derived from medicinal plants 119
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 119
Novel mutual prodrug of 5-fluorouracil and heme oxygenase-1 inhibitor (5-FU/HO-1 hybrid): design and preliminary in vitro evaluation 118
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 117
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 117
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 115
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 114
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 114
Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats 111
Characterization of sigma 1 receptor antagonist CM-304 and its analog, AZ-66: Novel therapeutics against allodynia and induced pain 111
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 109
Divergent cytotoxic and metabolically stimulative functions of sigma-2 receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives 107
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 106
Discovery of 3-(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligands 106
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 102
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 101
Benzimidazolone-based selective σ2 receptor ligands: Synthesis and pharmacological evaluation 100
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 98
Bioanalytical method development and pharmacokinetics of MCI-92, a sigma-1 receptor ligand 97
Synthesis and in Vitro Evaluation of CAPE Derivatives as Ferroptosis Inducers in Triple Negative Breast Cancer 92
Lauric acid-based thermosensitive delivery system for the treatment of head and neck squamous cell carcinoma 79
The Inhibition of Neuropathic Pain Incited by Nerve Injury and Accompanying Mood Disorders by New Heme Oxygenase-1 Inducers: Mechanisms Implicated 78
New alkylpiperazines as 5-HT7R ligands 77
Exploring 1-adamantanamine as an alternative amine moiety for metabolically labile azepane ring in newly synthesized benzo[d]thiazol-2(3H)one σ receptor ligands 77
In vitro and in silico analysis of imatinib analogues as anti- Trypanosoma cruzi drug candidates 75
Strategies to improve resveratrol systemic and topical bioavailability: An update 75
Novel selective ligands for the serotonergic 5-HT7 receptor: tricyclic derivatives Bearing the pyrimido-4(3H)-one ring 71
Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT1A and 5-HT7 receptor ligands 68
New thienopyrimidine and quinazoline derivatives as potential 5-HT7 receptor ligands. 67
New alkylpiperazines as 5-HT7R ligands 67
New homo and hetero bis-arylpiperazine and bis-benzylpiperazine derivatives as 5-HT7R selective ligands: design and synthesis 67
UPLC-MS/MS method for the quantification of MCI-77, a novel sigma-1 receptor ligand, and its application to pharmacokinetic studies 65
New 5-Ht7 Receptor Ligands As Potential Antidepressant Agents. 64
Thieno[3,2-d]pyrimidine as a scaffold for 5-HT7 receptor ligands 61
Laboratory-Scale Semipreparative Enantioresolution of Phenylethanolic-Azole Heme Oxygenase-1 Inhibitors 57
Novel benzothiazolones and benzoxazolones-based σ receptor ligands: synthesis and preliminary pharmacological evaluation against allodynia 49
Semi-Synthetic H2S Releasing Compounds with Antioxidant and Vasorelaxant Properties 29
The Sigma1 receptor antagonist CM304 potentiates the antinociceptive effects of the cannabinoid receptor agonist delta9-tetrahydrocannabinol in rats and mice 11
Development of 5-fluorouracil and heme oxygenase 1 inhibitor mutual prodrugs as an innovative anticancer strategy 1
Totale 7.491
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Categoria #
all - tutte 23.206
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 23.206
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202119 0 0 0 0 0 0 0 0 0 0 0 19
2021/2022507 36 57 59 16 67 17 69 33 17 27 11 98
2022/2023857 69 74 38 116 67 126 3 141 147 15 52 9
2023/2024439 20 52 21 22 48 110 5 28 1 18 65 49
2024/20251.659 24 255 67 134 294 150 168 51 126 144 138 108
2025/20263.502 216 150 733 190 475 710 302 94 251 197 157 27
Totale 7.491