IRIS
INTAGLIATA, SEBASTIANO
 Distribuzione geografica
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Continente #
NA - Nord America 2.537
EU - Europa 1.400
AS - Asia 1.244
SA - Sud America 275
AF - Africa 176
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5.635
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Nazione #
US - Stati Uniti d'America 2.493
IT - Italia 823
SG - Singapore 668
CN - Cina 357
BR - Brasile 247
IE - Irlanda 193
RU - Federazione Russa 105
CI - Costa d'Avorio 101
DE - Germania 70
VN - Vietnam 62
SN - Senegal 47
KR - Corea 40
UA - Ucraina 35
CA - Canada 31
GB - Regno Unito 28
FR - Francia 26
FI - Finlandia 23
JP - Giappone 21
ES - Italia 18
IN - India 17
PL - Polonia 17
BD - Bangladesh 14
IQ - Iraq 13
CZ - Repubblica Ceca 12
AR - Argentina 10
NL - Olanda 9
SE - Svezia 9
TR - Turchia 9
ZA - Sudafrica 8
HK - Hong Kong 7
MX - Messico 7
BJ - Benin 6
CH - Svizzera 6
ID - Indonesia 6
LT - Lituania 5
VE - Venezuela 5
AT - Austria 4
EC - Ecuador 4
EG - Egitto 4
IR - Iran 4
UZ - Uzbekistan 4
AZ - Azerbaigian 3
CL - Cile 3
DO - Repubblica Dominicana 3
GR - Grecia 3
JO - Giordania 3
KE - Kenya 3
RO - Romania 3
AE - Emirati Arabi Uniti 2
AL - Albania 2
AU - Australia 2
BG - Bulgaria 2
BY - Bielorussia 2
CM - Camerun 2
CO - Colombia 2
GT - Guatemala 2
GY - Guiana 2
KG - Kirghizistan 2
LU - Lussemburgo 2
MA - Marocco 2
NG - Nigeria 2
NP - Nepal 2
OM - Oman 2
PK - Pakistan 2
BE - Belgio 1
HU - Ungheria 1
IL - Israele 1
JM - Giamaica 1
KZ - Kazakistan 1
LB - Libano 1
MT - Malta 1
PE - Perù 1
PS - Palestinian Territory 1
PY - Paraguay 1
SA - Arabia Saudita 1
TN - Tunisia 1
TW - Taiwan 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 5.635
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Città #
Dallas 634
Singapore 376
Santa Clara 285
Chandler 276
Catania 204
Dublin 189
Chicago 178
Ashburn 126
Abidjan 101
Beijing 100
Boardman 84
Hefei 79
Houston 68
Cambridge 51
Lawrence 48
Dakar 47
Andover 46
Los Angeles 39
Seoul 39
Redmond 38
Naples 37
Rome 35
Civitanova Marche 34
São Paulo 33
Jacksonville 30
Moscow 30
Munich 26
Palermo 23
Des Moines 22
Wilmington 22
Nanjing 21
Tokyo 21
Milan 20
New York 19
Boydton 18
Buffalo 18
Ho Chi Minh City 18
The Dalles 18
Bremen 17
Columbus 17
Hanoi 16
Dong Ket 15
Messina 15
Council Bluffs 14
Toronto 14
Seattle 12
Turku 12
Warsaw 11
Salerno 10
Civitavecchia 9
Pozzallo 9
Viagrande 9
Baghdad 8
Brooklyn 8
Gravina di Catania 8
Hebei 8
Aci Catena 7
Brno 7
Denver 7
Gela 7
Lappeenranta 7
London 7
Ottawa 7
Saint Petersburg 7
San Francisco 7
Siracusa 7
Stockholm 7
Turin 7
Barcelona 6
Cotonou 6
Ferrara di Monte Baldo 6
Foggia 6
Fortaleza 6
Garbagnate Milanese 6
Goiânia 6
Johannesburg 6
Poplar 6
Washington 6
Amsterdam 5
Atlanta 5
Brasília 5
Curitiba 5
Fairfield 5
Hong Kong 5
Jakarta 5
Nanchang 5
Orem 5
Padova 5
Raffadali 5
Reggio Calabria 5
Santa Maria di Licodia 5
Shenyang 5
Tremestieri Etneo 5
Ankara 4
Boston 4
Chennai 4
Florence 4
Helsinki 4
Maceió 4
Madrid 4
Totale 3.912
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Nome #
Haloperidol drug repurposing unveils ferroptosis involvement in breast cancer cells 228
Design, synthesis, and pharmacological evaluation of NO donor-sigma receptors hybrids for the treatment of cancer 157
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 151
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 146
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 144
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 142
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 119
Solid lipid nanoparticles loading idebenone ester with pyroglutamic acid: In vitro antioxidant activity and in vivo topical efficacy 119
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 117
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 114
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 112
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 109
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 108
New arylethanolimidazole derivatives as HO-1 inhibitors with cytotoxicity against MCF-7 breast cancer cells 107
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 105
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 104
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells 103
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 102
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 102
Combination of heme oxygenase-1 inhibitors and temozolomide to improve the anticancer effect in glioblastoma 101
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 101
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 96
The analgesic potential of glycosides derived from medicinal plants 95
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 95
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 95
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 94
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 93
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 93
Correction to Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 92
Ginseng and heme oxygenase-1: The link between an old herb and a new protective system 91
In vitro antioxidant and anti-glycation activity of resveratrol and its novel triester with trolox 91
Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In Vivo 90
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 90
Novel mutual prodrug of 5-fluorouracil and heme oxygenase-1 inhibitor (5-FU/HO-1 hybrid): design and preliminary in vitro evaluation 89
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 89
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 87
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 85
Characterization of sigma 1 receptor antagonist CM-304 and its analog, AZ-66: Novel therapeutics against allodynia and induced pain 84
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 83
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 83
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 83
Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats 81
Discovery of 3-(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligands 79
Benzimidazolone-based selective σ2 receptor ligands: Synthesis and pharmacological evaluation 75
Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain 74
Divergent cytotoxic and metabolically stimulative functions of sigma-2 receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives 73
Bioanalytical method development and pharmacokinetics of MCI-92, a sigma-1 receptor ligand 72
Exploring 1-adamantanamine as an alternative amine moiety for metabolically labile azepane ring in newly synthesized benzo[d]thiazol-2(3H)one σ receptor ligands 67
Synthesis and in Vitro Evaluation of CAPE Derivatives as Ferroptosis Inducers in Triple Negative Breast Cancer 65
In vitro and in silico analysis of imatinib analogues as anti- Trypanosoma cruzi drug candidates 62
Strategies to improve resveratrol systemic and topical bioavailability: An update 61
Lauric acid-based thermosensitive delivery system for the treatment of head and neck squamous cell carcinoma 59
New alkylpiperazines as 5-HT7R ligands 58
The Inhibition of Neuropathic Pain Incited by Nerve Injury and Accompanying Mood Disorders by New Heme Oxygenase-1 Inducers: Mechanisms Implicated 58
New thienopyrimidine and quinazoline derivatives as potential 5-HT7 receptor ligands. 58
New 5-Ht7 Receptor Ligands As Potential Antidepressant Agents. 56
Novel selective ligands for the serotonergic 5-HT7 receptor: tricyclic derivatives Bearing the pyrimido-4(3H)-one ring 55
New homo and hetero bis-arylpiperazine and bis-benzylpiperazine derivatives as 5-HT7R selective ligands: design and synthesis 54
Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT1A and 5-HT7 receptor ligands 52
New alkylpiperazines as 5-HT7R ligands 51
Thieno[3,2-d]pyrimidine as a scaffold for 5-HT7 receptor ligands 50
UPLC-MS/MS method for the quantification of MCI-77, a novel sigma-1 receptor ligand, and its application to pharmacokinetic studies 47
Laboratory-Scale Semipreparative Enantioresolution of Phenylethanolic-Azole Heme Oxygenase-1 Inhibitors 45
Novel benzothiazolones and benzoxazolones-based σ receptor ligands: synthesis and preliminary pharmacological evaluation against allodynia 39
Totale 5.780
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Categoria #
all - tutte 19.455
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 19.455
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202182 0 0 0 0 0 6 14 4 6 10 23 19
2021/2022507 36 57 59 16 67 17 69 33 17 27 11 98
2022/2023857 69 74 38 116 67 126 3 141 147 15 52 9
2023/2024439 20 52 21 22 48 110 5 28 1 18 65 49
2024/20251.659 24 255 67 134 294 150 168 51 126 144 138 108
2025/20261.791 216 150 733 190 475 27 0 0 0 0 0 0
Totale 5.780