IRIS
INTAGLIATA, SEBASTIANO
 Distribuzione geografica
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Continente #
NA - Nord America 1.567
EU - Europa 1.207
AS - Asia 539
SA - Sud America 154
AF - Africa 134
OC - Oceania 2
Totale 3.603
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Nazione #
US - Stati Uniti d'America 1.542
IT - Italia 780
SG - Singapore 350
IE - Irlanda 191
BR - Brasile 146
CN - Cina 132
CI - Costa d'Avorio 78
DE - Germania 58
SN - Senegal 47
RU - Federazione Russa 45
UA - Ucraina 31
CA - Canada 22
FR - Francia 22
VN - Vietnam 17
GB - Regno Unito 13
ES - Italia 12
CZ - Repubblica Ceca 9
FI - Finlandia 8
IN - India 7
CH - Svizzera 6
PL - Polonia 6
TR - Turchia 6
NL - Olanda 5
AR - Argentina 4
AT - Austria 3
GR - Grecia 3
HK - Hong Kong 3
IQ - Iraq 3
JP - Giappone 3
RO - Romania 3
SE - Svezia 3
UZ - Uzbekistan 3
VE - Venezuela 3
AL - Albania 2
AU - Australia 2
BD - Bangladesh 2
CM - Camerun 2
KE - Kenya 2
KG - Kirghizistan 2
LU - Lussemburgo 2
MA - Marocco 2
NG - Nigeria 2
OM - Oman 2
AZ - Azerbaigian 1
BE - Belgio 1
BG - Bulgaria 1
BY - Bielorussia 1
CL - Cile 1
DO - Repubblica Dominicana 1
EG - Egitto 1
HU - Ungheria 1
IR - Iran 1
JM - Giamaica 1
KR - Corea 1
KZ - Kazakistan 1
LB - Libano 1
MT - Malta 1
MX - Messico 1
NP - Nepal 1
PK - Pakistan 1
PS - Palestinian Territory 1
TW - Taiwan 1
Totale 3.603
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Città #
Chandler 276
Santa Clara 275
Singapore 193
Catania 192
Dublin 187
Chicago 173
Boardman 84
Abidjan 78
Ashburn 68
Houston 66
Cambridge 51
Lawrence 48
Dakar 47
Andover 46
Redmond 38
Naples 36
Civitanova Marche 34
Jacksonville 30
Rome 26
Des Moines 22
Wilmington 22
Nanjing 21
Palermo 21
São Paulo 20
Munich 19
Boydton 18
Bremen 17
Milan 17
Dong Ket 15
Messina 15
Toronto 14
Beijing 13
Council Bluffs 12
Seattle 11
Salerno 10
Civitavecchia 9
Pozzallo 9
Viagrande 9
Hebei 8
Aci Catena 7
Brno 7
Gela 7
Ottawa 7
Saint Petersburg 7
Siracusa 7
Turin 7
Barcelona 6
Ferrara di Monte Baldo 6
Foggia 6
Garbagnate Milanese 6
Moscow 6
Fairfield 5
Gravina di Catania 5
Nanchang 5
Padova 5
Raffadali 5
Reggio Calabria 5
Santa Maria di Licodia 5
Shenyang 5
Florence 4
Fortaleza 4
Goiânia 4
Helsinki 4
Lappeenranta 4
Los Angeles 4
Madrid 4
Milazzo 4
Misterbianco 4
Ribeirão Preto 4
Tremestieri Etneo 4
Vicenza 4
Washington 4
Brasília 3
Bucharest 3
Changsha 3
Ferrara 3
Gunzenhausen 3
Latina 3
London 3
Lucca 3
Maceió 3
Marseille 3
Mascalucia 3
Modica 3
New Haven 3
Norwalk 3
Novara 3
Paris 3
Phoenix 3
Pune 3
Rimini 3
Roccalumera 3
San Mateo 3
Tashkent 3
The Dalles 3
Tokyo 3
Venice 3
Villamagna 3
Abuja 2
Amsterdam 2
Totale 2.503
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Nome #
Design, synthesis, and pharmacological evaluation of NO donor-sigma receptors hybrids for the treatment of cancer 122
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 115
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity 104
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 101
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 97
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 90
Solid lipid nanoparticles loading idebenone ester with pyroglutamic acid: In vitro antioxidant activity and in vivo topical efficacy 88
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 85
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 84
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 84
New arylethanolimidazole derivatives as HO-1 inhibitors with cytotoxicity against MCF-7 breast cancer cells 81
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 80
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 77
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 76
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 75
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 73
Examination of the Novel Sigma‐1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti‐Allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use 73
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 73
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 70
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 70
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 69
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 69
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 69
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 68
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 68
Novel mutual prodrug of 5-fluorouracil and heme oxygenase-1 inhibitor (5-FU/HO-1 hybrid): design and preliminary in vitro evaluation 64
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 64
Ginseng and heme oxygenase-1: The link between an old herb and a new protective system 63
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 62
Lipid nanoparticles traverse non-corneal path to reach the posterior eye segment: In vivo evidence 61
Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In Vivo 60
In vitro antioxidant and anti-glycation activity of resveratrol and its novel triester with trolox 59
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells 58
Divergent cytotoxic and metabolically stimulative functions of sigma-2 receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives 58
Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats 58
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 57
The analgesic potential of glycosides derived from medicinal plants 57
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 56
Benzimidazolone-based selective σ2 receptor ligands: Synthesis and pharmacological evaluation 53
Characterization of sigma 1 receptor antagonist CM-304 and its analog, AZ-66: Novel therapeutics against allodynia and induced pain 52
Bioanalytical method development and pharmacokinetics of MCI-92, a sigma-1 receptor ligand 51
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 49
Exploring 1-adamantanamine as an alternative amine moiety for metabolically labile azepane ring in newly synthesized benzo[d]thiazol-2(3H)one σ receptor ligands 49
Discovery of 3-(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligands 47
Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain 46
Combination of heme oxygenase-1 inhibitors and temozolomide to improve the anticancer effect in glioblastoma 41
Novel selective ligands for the serotonergic 5-HT7 receptor: tricyclic derivatives Bearing the pyrimido-4(3H)-one ring 41
Strategies to improve resveratrol systemic and topical bioavailability: An update 41
New homo and hetero bis-arylpiperazine and bis-benzylpiperazine derivatives as 5-HT7R selective ligands: design and synthesis 40
New thienopyrimidine and quinazoline derivatives as potential 5-HT7 receptor ligands. 39
Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT1A and 5-HT7 receptor ligands 37
Correction to Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 34
Laboratory-Scale Semipreparative Enantioresolution of Phenylethanolic-Azole Heme Oxygenase-1 Inhibitors 31
New 5-Ht7 Receptor Ligands As Potential Antidepressant Agents. 30
Synthesis and in Vitro Evaluation of CAPE Derivatives as Ferroptosis Inducers in Triple Negative Breast Cancer 29
New alkylpiperazines as 5-HT7R ligands 29
In vitro and in silico analysis of imatinib analogues as anti- Trypanosoma cruzi drug candidates 28
UPLC-MS/MS method for the quantification of MCI-77, a novel sigma-1 receptor ligand, and its application to pharmacokinetic studies 28
Thieno[3,2-d]pyrimidine as a scaffold for 5-HT7 receptor ligands 26
Novel benzothiazolones and benzoxazolones-based σ receptor ligands: synthesis and preliminary pharmacological evaluation against allodynia 25
Lauric acid-based thermosensitive delivery system for the treatment of head and neck squamous cell carcinoma 22
The Inhibition of Neuropathic Pain Incited by Nerve Injury and Accompanying Mood Disorders by New Heme Oxygenase-1 Inducers: Mechanisms Implicated 22
New alkylpiperazines as 5-HT7R ligands 19
Totale 3.747
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Categoria #
all - tutte 14.055
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 14.055
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202033 0 0 0 0 0 0 0 0 0 0 14 19
2020/2021204 6 9 41 12 54 6 14 4 6 10 23 19
2021/2022507 36 57 59 16 67 17 69 33 17 27 11 98
2022/2023857 69 74 38 116 67 126 3 141 147 15 52 9
2023/2024439 20 52 21 22 48 110 5 28 1 18 65 49
2024/20251.417 24 255 67 134 294 150 168 51 126 144 4 0
Totale 3.747