IRIS
COPANI, Agata Graziella
 Distribuzione geografica
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Continente #
NA - Nord America 5.471
AS - Asia 2.300
EU - Europa 2.287
SA - Sud America 434
AF - Africa 128
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 7
Totale 10.634
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Nazione #
US - Stati Uniti d'America 5.206
SG - Singapore 1.080
CN - Cina 768
IE - Irlanda 661
UA - Ucraina 625
BR - Brasile 404
IT - Italia 325
CA - Canada 248
HK - Hong Kong 210
RU - Federazione Russa 187
DE - Germania 118
SE - Svezia 108
CI - Costa d'Avorio 68
GB - Regno Unito 67
IN - India 56
KR - Corea 35
SN - Senegal 35
FI - Finlandia 27
CH - Svizzera 26
FR - Francia 21
PL - Polonia 21
IR - Iran 19
VN - Vietnam 19
AT - Austria 17
NL - Olanda 17
UZ - Uzbekistan 17
PK - Pakistan 16
TR - Turchia 14
ZA - Sudafrica 14
CZ - Repubblica Ceca 13
ES - Italia 13
IQ - Iraq 11
JP - Giappone 11
BE - Belgio 10
BD - Bangladesh 9
GR - Grecia 9
MX - Messico 9
SA - Arabia Saudita 9
AR - Argentina 8
EU - Europa 7
AU - Australia 6
LB - Libano 6
BG - Bulgaria 5
VE - Venezuela 5
AZ - Azerbaigian 4
EC - Ecuador 4
IL - Israele 4
KE - Kenya 4
RO - Romania 4
UY - Uruguay 4
CO - Colombia 3
NG - Nigeria 3
CL - Cile 2
CR - Costa Rica 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
HU - Ungheria 2
JM - Giamaica 2
KZ - Kazakistan 2
NO - Norvegia 2
NP - Nepal 2
PE - Perù 2
TN - Tunisia 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
BA - Bosnia-Erzegovina 1
BO - Bolivia 1
BY - Bielorussia 1
EG - Egitto 1
ET - Etiopia 1
HN - Honduras 1
HR - Croazia 1
JO - Giordania 1
KH - Cambogia 1
KW - Kuwait 1
LT - Lituania 1
LU - Lussemburgo 1
MN - Mongolia 1
MY - Malesia 1
NZ - Nuova Zelanda 1
OM - Oman 1
PR - Porto Rico 1
PS - Palestinian Territory 1
PT - Portogallo 1
PY - Paraguay 1
Totale 10.634
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Città #
Santa Clara 875
Jacksonville 675
Singapore 663
Dublin 660
Chandler 656
Boardman 310
Chicago 249
Nanjing 210
Ashburn 196
Toronto 190
Cambridge 189
Andover 186
Lawrence 185
Catania 126
San Mateo 116
Wilmington 95
Des Moines 80
Hefei 77
Nanchang 76
Civitanova Marche 72
Abidjan 68
Hebei 64
Saint Petersburg 59
Houston 50
Shenyang 49
Changsha 47
Beijing 46
Jiaxing 45
Ottawa 43
Bremen 41
Los Angeles 37
Dakar 35
Seoul 35
Munich 31
São Paulo 30
The Dalles 29
Seattle 28
Tianjin 27
Council Bluffs 26
Columbus 25
Grafing 24
New York 20
Helsinki 18
Pune 18
San Francisco 18
Leawood 17
Moscow 17
Norwalk 17
Rio de Janeiro 15
Ann Arbor 14
Washington 14
Augusta 13
Brooklyn 13
Kunming 13
Mumbai 13
Falls Church 11
London 11
Ardabil 10
Belo Horizonte 10
Brussels 10
Jinan 10
Johannesburg 10
Phoenix 10
Tokyo 10
Warsaw 10
Dong Ket 9
Hangzhou 9
Liberty Lake 9
Turin 9
Atlanta 8
Guangzhou 8
Montreal 8
Brasília 7
Charlotte 7
Monmouth Junction 7
Naples 7
Porto Alegre 7
Amsterdam 6
Baghdad 6
Boston 6
Curitiba 6
Fairfield 6
Frankfurt Am Main 6
Karachi 6
Messina 6
Tashkent 6
Turku 6
Vercelli 6
Carapicuíba 5
Changchun 5
Dallas 5
Den Haag 5
Edinburgh 5
Fuzhou 5
Jeddah 5
Lahore 5
Milan 5
Santo André 5
Stockholm 5
Tappahannock 5
Totale 7.268
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Nome #
N-acetylcysteine causes analgesia by activating group II metabotropic glutamate receptors 280
A major role for astrocytes in the neuroprotective effect of estrogen 111
Role of DNA polymerase expression in beta-amyloyd-induced neuronal death 105
Hyperalgesic activity of kisspeptin in mice 92
β-amyloid-activated cell cycle in SH-SY5Y neuroblastoma cells: Correlation with the MAP kinase pathway 91
Ac-LPFFD-Th: A Trehalose-Conjugated Peptidomimetic as a Strong Suppressor of Amyloid- Oligomer Formation and Cytotoxicity 90
Increased heat pain tolerance but hyperalgesia to tonic inflammatory pain in the CRND8 mouse model of Alzheimer’s disease 89
Beta-amyloid monomers are neuroprotective 89
Neurobiological links between depression and AD: the role of TGF-β1 signaling as a new pharmacological target 89
Beta-Amyloid Monomer and Insulin/IGF-1 Signaling in Alzheimer's Disease 88
L-acetylcarnitine: a proposed therapeutic agent for painful peripheral neuropathies 88
Metabotropic glutamate receptors in glial cells: A New Potential Target for Neuroprotection? 88
A dual mechanism of neuroprotection by transforming growth factor-β1 against β-amyloid neurotoxicity 86
Acetyl-L-carnitine in neuropathic pain: experimental data 85
Activation of metabotropic glutamate receptor protects cultured neurons against apoptosis induced by beta-amyloid peptide 84
Activation of metabotropic glutamate receptors prevents neuronal apoptosis in culture 81
The antineoplastic drug flavopiridol reverses memory impairment induced by Amyloid-ß1-42 oligomers in mice 81
A ratiometric naphthalimide sensor for live cell imaging of copper(I) 81
Acrivation of cell cycle-associated proteins in neuronal death: a mandatory or dispensable path? 80
Alzheimer's disease: brain expression of a metabolic disorder? 80
Molecular connections between DNA replication and cell death in beta-amyloid-treated neurons 79
Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity 78
Alzheimer's disease research enters a "new cycle": how significant? 76
Anabolic-androgenic steroid effects on cultured cortical neurons 76
The monomer state of beta-amyloid: where the Alzheimer's disease protein meets physiology 75
Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration 75
A new function for ß-amyloid monomers 75
Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells 74
Effect of nitric oxide synthase induction on the expression of mitochondrial respiratory chain enzyme subunits in mixed cortical and astroglial cell cultures 74
A NANOPLATFORM BASED ON SILICA CORE-SHELL NANOPARTICLES AND CHEMOSENSORS FOR MONITORING INTRACELLULAR DYNAMICS OF COPPER TRAFFICKING 74
Novel neuronal targets for the acetylcholinesterase inhibitor donepezil 73
A role for estrogen in early differentiation: characterization in neurospheres 73
Erratic expression of DNA polymerases by beta-amyloid causes neuronal death 72
Abeta(25-35) and its C- and/or N-blocked derivatives: Copper driven structural features and neurotoxicity 72
A dual mechanism of neuroprotection by transforming growth factor-β1 against β-amyloid neurotoxicity 71
The nature of the cell cycle in neurons: Focus on a "non-canonical" pathway of DNA replication causally related to death 71
The cell cycle molecules behind neurodegeneration in Alzheimer's disease: perspectives for drug development 70
beta-Amyloid neurotoxicity: a discussion of in vitro findings 70
TGFbeta1 pathway as a new target for neuroprotection in Alzheimer's disease 69
PHARMACOLOGICAL EVALUATION OF POTENT SIGMA LIGANDS IN β-AMYLOID INDUCED NEURODEGENERATION 69
Pituitary adenylate cyclase activating polypeptide prevents apoptosis in cultured cerebellar granule neurons 69
Metabotropic glutamate receptors in neurodegeneration/neuroprotection: Still a hot topic? 68
Fluoxetine prevents Aβ1-42-induced toxicity via a paracrine signaling mediated by transforming-growth-factor-β1 68
A New Ratiometric Lysosomal Copper(II) Fluorescent Probe To Map a Dynamic Metallome in Live Cells 68
The CC genotype of transforming growth factor-β1 increases the risk of late-onset Alzheimer's disease and is associated with AD-related depression 67
Depression and Alzheimer's disease: neurobiological links and common pharmacological targets 67
The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders 66
Glia mediates the neuroprotective action of estradiol on {beta}-amyloid-induced neuronal death 66
Repeated injections of piracetam improve spatial learning and increase the stimulation of inositol phospholipid hydrolysis by excitatory amino acids in aged rats 65
From cell cycle activation to inhibition of the Wnt pathway: a linking bridge between beta-amyloid and neruodegenration in Alzheimer's disease 65
Biomolecule And Cell Interactions Studied By Surface Plasmon Resonance Imaging 65
A novel rat gene encoding a Humanin-like peptide endowed with broad neuroprotective activity 65
Neuroprotective effects of sigma-1 receptor agonists against beta-amyloid-induced toxicity 65
L-acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors 64
Progenitor cells from the adult mouse brain acquire a neuronal phenotype in response to beta-amyloid 64
Alzheimer's disease 63
Neurotoxic properties of the anabolic androgenic steroids nandrolone and methandrostenolone in primary neuronal cultures 63
Amyloid Beta monomers regulate cyclic adenosine monophosphate response element binding protein functions by activating type-1 insulin-like growth factor receptors in neuronal cells 63
DNA polymerase-beta is expressed early in neurons of Alzheimer's disease brain and is loaded into DNA replication forks in neurons challenged with beta-amyloid 62
Two sides of the same coin: Wnt signaling in neurodegeneration and neuro-oncology 62
DIFFERENTIATING EFFECTS OF B-AMYLOID IN CULTURED NEUROSPHERES 62
The Wnt pathway, cell-cycle activation and beta-amyloid: novel therapeutic strategies in Alzheimer's disease? 62
Beta-amyloid increases neuronal susceptibility to injury by glucose deprivation 61
Specific binding sites for inositolhexakisphosphate in brain and anterior pituitary 61
Expression and coupling to polyphosphoinositide hydrolysis of group I metabotropic glutamate receptors in early postnatal and adult rat brain 61
L-Acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors 61
Group-I metabotropic glutamate receptors: hypotheses to explain their dual role in neurotoxicity and neuroprotection. Neuropharmacology 61
Multiple transducing pathways participate to the induction of a mitotic cell cycle by b-amyloid peptide in differentiated neuroblastoma cells 61
Metabotropic glutamate receptor subtypes influence neuronal degeneration through different mechanisms 61
Differentiating effects of ß-amyloid on neural progenitors cells 61
mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists 60
Stress enhances the expression of the Wnt antagonist, Dickkopf-1, in the mouse hippocampus: A key protein of stress-induced neurodegeneration? 59
Epigenetic control of chronic pain mechanism 59
TGF-ß1 protects against Aß-neurotoxicity via the phosphatidylinositol-3-kinase pathway 59
Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain 59
Metabotropic receptors as target for drugs of potential use in the treatment of neuropathic pain 59
An enhanced expression of the immediate early gene, Egr-1, is associated with neuronal apoptosis in culture 58
Plasticity of metabotropic glutamate receptors in physiological and pathological conditions (cap 10) 58
Effect of no synthase induction in astroglial and neuronal cell cultures on the expression of mitochondrial respiratory chain enzyme subunits 58
NMDA and Metabotropic receptors prevent apoptosis by trophic deprivation in cerebellar granule cells developing in primary culture 58
Astrocyte-like cells as a main target for estrogen action during neuronal differentiation 58
An activity-dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors 58
Metabotropic glutamate receptor agonists stimulate polyphosphoinositide hydrolysis in primary cultures of rat hepatocytes 58
Neuroprotective activity of chemokines against N-methyl-D-aspartate or beta-amyloid-induced toxicity in culture 58
β-amyloid monomers drive up neuronal aerobic glycolysis in response to energy stressors 58
Protective action of idebenone against excitotoxic degeneration in cultured cortical neurons 57
Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders? 57
Distinct role of mGlu1 and mGlu5 receptor activation in the development of the cerebellar cortex 57
Metabotropic glutamate receptors and neurodegeneration 56
Mitotic signaling by beta-amyloid causes neuronal death 56
TGF-beta1 targets the GSK-3beta/beta-catenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts 56
Nicergoline, a drug used for age-dependent cognitive impairment, protects cultured neurons against beta-amyloid toxicity 56
Red-Light-Photosensitized Tyrosine 10 Nitration of β-Amyloid1-42 Diverts the Protein from Forming Toxic Aggregates. 54
DNA polymerase-β mediates the neurogenic effect of β-amyloid protein in cultured subventricular zone neurospheres 54
Nootropic drugs positively modulate alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-sensitive glutamate receptors in neuronal cultures 54
Enhanced expression of ERalpha in astrocytes modifies the response of cortical neurons to beta-amyloid toxicity 54
The CDC2 I-G-T haplotype associated with the APOE varepsilon4 allele increases the risk of sporadic Alzheimer's disease in Sicily 54
From cell cycle activation to the inhibition of the Wnt pathway: a hypothesis of how neurons die in response to ß-amyloid 54
METABOTROPIC GLUTAMMATE RECEPTORS AND NEURONAL TOXICITY 54
Evidence for an activity-dependent switch in the regulation of excitotoxic neurodegeneration by group-I mGlu receptors 53
Totale 7.044
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Categoria #
all - tutte 42.834
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 42.834
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.090 16 95 125 6 301 30 126 5 96 1 240 49
2021/20221.362 184 189 4 22 212 8 196 41 125 7 67 307
2022/20232.334 197 61 20 204 227 406 6 557 548 13 70 25
2023/2024818 54 107 33 60 43 146 39 74 5 30 148 79
2024/20253.447 32 539 203 143 742 410 93 161 257 329 240 298
2025/2026398 398 0 0 0 0 0 0 0 0 0 0 0
Totale 10.910