IRIS
PREZZAVENTO, Orazio
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 7.506
EU - Europa 3.725
AS - Asia 3.344
SA - Sud America 599
AF - Africa 568
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 3
Totale 15.756
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 7.225
SG - Singapore 1.670
RU - Federazione Russa 1.156
CN - Cina 884
IT - Italia 766
IE - Irlanda 538
BR - Brasile 486
CI - Costa d'Avorio 340
UA - Ucraina 338
VN - Vietnam 321
DE - Germania 272
CA - Canada 218
FR - Francia 184
GB - Regno Unito 119
SN - Senegal 83
KR - Corea 76
NG - Nigeria 72
FI - Finlandia 67
IN - India 67
SE - Svezia 63
JP - Giappone 54
BD - Bangladesh 45
AR - Argentina 44
PL - Polonia 40
MX - Messico 38
ES - Italia 37
ID - Indonesia 36
HK - Hong Kong 32
IQ - Iraq 31
NL - Olanda 30
TR - Turchia 28
UZ - Uzbekistan 24
CH - Svizzera 22
ZA - Sudafrica 19
AT - Austria 18
EC - Ecuador 18
GR - Grecia 14
MA - Marocco 13
VE - Venezuela 13
BE - Belgio 12
CO - Colombia 12
CZ - Repubblica Ceca 12
KE - Kenya 12
CL - Cile 9
LB - Libano 9
TN - Tunisia 9
AU - Australia 8
EG - Egitto 8
IR - Iran 8
PK - Pakistan 8
HU - Ungheria 7
ET - Etiopia 6
JM - Giamaica 6
NP - Nepal 6
PY - Paraguay 6
AL - Albania 5
LT - Lituania 5
RS - Serbia 5
SA - Arabia Saudita 5
UY - Uruguay 5
DO - Repubblica Dominicana 4
JO - Giordania 4
KG - Kirghizistan 4
KZ - Kazakistan 4
AE - Emirati Arabi Uniti 3
AZ - Azerbaigian 3
BO - Bolivia 3
CR - Costa Rica 3
HR - Croazia 3
IL - Israele 3
MY - Malesia 3
OM - Oman 3
PH - Filippine 3
TH - Thailandia 3
BB - Barbados 2
BG - Bulgaria 2
DZ - Algeria 2
EU - Europa 2
NZ - Nuova Zelanda 2
PE - Perù 2
RO - Romania 2
SV - El Salvador 2
SY - Repubblica araba siriana 2
AG - Antigua e Barbuda 1
AO - Angola 1
BY - Bielorussia 1
BZ - Belize 1
DK - Danimarca 1
DM - Dominica 1
GA - Gabon 1
GE - Georgia 1
GH - Ghana 1
GT - Guatemala 1
GY - Guiana 1
HN - Honduras 1
KH - Cambogia 1
LK - Sri Lanka 1
LV - Lettonia 1
MD - Moldavia 1
ME - Montenegro 1
Totale 15.745
Salva come PNG Salva come JPEG
Città #
Dallas 1.209
Singapore 997
Chandler 780
Santa Clara 740
Dublin 537
Moscow 512
San Jose 423
Jacksonville 417
Chicago 401
Ashburn 376
Abidjan 340
Boardman 212
Catania 187
Houston 183
Nanjing 177
Beijing 151
Andover 149
Cambridge 149
Lawrence 149
Toronto 140
Civitanova Marche 136
Lauterbourg 133
Los Angeles 129
Munich 113
Dakar 83
Des Moines 83
Ho Chi Minh City 83
Dong Ket 82
Seoul 76
Wilmington 71
New York 66
San Mateo 61
Council Bluffs 60
Grafing 60
Bremen 56
The Dalles 53
Nanchang 52
São Paulo 51
Tokyo 51
Hanoi 50
Shenyang 50
Helsinki 49
Columbus 46
Buffalo 44
Hefei 38
Saint Petersburg 37
Jiaxing 36
Changsha 35
Lagos 33
Warsaw 33
Ottawa 32
Tianjin 31
Hong Kong 29
Hebei 28
Abuja 26
Orem 26
Rio de Janeiro 26
Jakarta 24
Atlanta 23
Falls Church 21
London 20
Montreal 19
Phoenix 19
Denver 18
Mexico City 18
Brooklyn 17
Leawood 16
Milan 16
Belo Horizonte 15
Madrid 15
Naples 15
Rome 15
Washington 15
Da Nang 14
San Francisco 14
Seattle 14
Baghdad 13
Norwalk 13
Port Harcourt 13
Pune 13
Centro 12
Dhaka 12
Stockholm 12
Tashkent 12
Brussels 11
Chennai 11
Frankfurt am Main 11
Jinan 11
Johannesburg 11
Ningbo 11
Palermo 11
Amsterdam 10
Guangzhou 10
Kunming 9
Manchester 9
Poplar 9
Quito 9
Zhengzhou 9
Ardabil 8
Augusta 8
Totale 10.963
Salva come PNG Salva come JPEG
Nome #
((2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist 320
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 295
Antioxidant properties and pharmacokinetic studies of new selective σ1 bifunctional ligands 205
(+)-Pentazocine attenuates SH-SY5Y cell death, oxidative stress and microglial migration induced by conditioned medium from activated microglia 204
1-Phenyl-3azabicyclo[3.1.0]hexane derivatives as new ligands for sigma receptors 203
(+)-Pentazocine reduces oxidative stress and apoptosis in microglia following hypoxia/reoxygenation injury 201
Antiproliferative activity of phenylbutyrate ester of haloperidol metabolite II [(±)-MRJF4] in prostate cancer cells 197
Design, synthesis, and pharmacological evaluation of NO donor-sigma receptors hybrids for the treatment of cancer 197
4-Nitro-2,1,3-benzoxadiazole derivatives as potential fluorescent sigma receptor probes 196
(+)-and (−)-Phenazocine enantiomers: evaluation of their dual opioid agonist/σ1 antagonist properties and antinociceptive effects 185
1,3-Diossolani e analoghi aperti come nuovi ligandi per il recettore Sigma 178
Antiangiogenic Effect of (±)-Haloperidol Metabolite II Valproate Ester [(±)-MRJF22] in Human Microvascular Retinal Endothelial Cells 175
Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis 174
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 173
A new sigma ligand, (+/-)-PPCC, antagonizes kappa opioid receptor-mediated antinociceptive effect 173
Antioxidant activity of (+)-Pentazocine on activated microglia 172
(+)-cis-N-ethyleneamino-N-normetazocine derivatives. Novel and selective sigma ligands with antagonist properties 164
(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties 164
Benzomorphan-based opioid ligands with mixed m agonist/d antagonist activity 159
A novel and selective σ1/2 receptor ligand (PO680C): binding properties and expression of tissue transglutaminase 157
R- ed S-LP2: sintesi, molecular docking e valutazione farmacologica 157
Haloperidol Metabolite II Valproate Ester (S)-(-)-MRJF22: Preliminary Studies as a Potential Multifunctional Agent Against Uveal Melanoma 155
Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review 154
Exploiting the Power of Stereochemistry in Drug Action: 3-[(2S,6S,11S)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide as Potent Sigma-1 Receptor Antagonist 152
Antinociceptive profile of LP1, a non-peptide multitarget opioid ligand. 151
Sigma-1 and Sigma-2 receptor ligands induce apoptosis and autophagy but have opposite effect on cell proliferation in uveal melanoma 149
Development of Sigma Receptors Nitric Oxide Photodonor Ligands with Antiproliferative Activity 148
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 147
Dual MOR/DOR agonist benzomorphan-based compounds for pain relief 145
(+)-Mr200 derivatives: modifications on the amino moiety. In vitro and in vivo pharmacological evaluation 143
Development of novel LP1-based analogues with enhanced delta opioid receptor profile 143
Anti-amnesic properties of (+/-)-PPCC, a novel sigma receptor ligand, on cognitive dysfunction induced by selective cholinergic lesion in rats 143
Nanoencapsulation strategies for the delivery of novel bifunctional antioxidant/σ1 selective ligands. 139
Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists 139
(+)-MR200 derivatives as potenzial new selective ligands 138
Anti-amnesic and neuroprotective actions of the sigma-1 receptor agonist (-)-MR22 in rats with selective cholinergic lesion and amyloid infusion 138
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 134
Synthesis and Structure-Activity Relationships of LP1 Derivatives: N-Methyl-N-phenylethylamino Analogues as Novel MOR Agonists 131
New selective Sigma-1/HDACi prodrugs for neurodegenerative disorders 130
Development of NO-releasing sigma receptor hybrids as anticancer agents 127
Tumor Targeting Sigma Receptor Ligands: Development of New Molecular Hybrids as Anticancer Therapeutics 126
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 126
Neuroprotective effect of the new sigma receptor ligands cis-(+) and cis-(–)-PPCC 124
Sigma-2 receptor ligands QSAR model dataset 123
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 122
Novel Sigma-1 receptor antagonists: From opioids to small molecules: What is new? 121
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 119
Molecular modeling studies of pseudouridine isoxazolidinyl nucleoside analogues as potential inhibitors of the pseudouridine 5'-monophosphate glycosidase 117
Morphing of ibogaine: A successful attempt into the search for sigma-2 receptor ligands 116
Novel Sigma Receptors Ligands-Nitric Oxide Photodonor: Molecular Hybrids for Double-Targeted Antiproliferative Effect 115
Synthesis and pharmacological evaluation of MRJF4 as new potential anticancer tool 114
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 114
The benzomorphan-based LP1 ligand is a suitable MOR/DOR agonist for chronic pain treatment 113
Synthesis of (+)-(1'R,2'S) and (1'S,2'R)-6,11 -dimethyl-1,2,3,4,5,6-hexahydro-3-[[2'-(alkoxycarbonyl)-2'- phenylcycloprophy]methyl]-2,6-methano-3-benzazocin-8-ol. Comparison of the affinities for sigma(1) and opioid receptors with in the diastereoisomeric MPCB and CCB 111
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 110
CCB, a novel specific kappa opioid agonist, which discriminates between opioid and sigma 1 recognition sites 110
Structure-Activity Relationships within a Series of σ1 and σ2 Receptor Ligands: Identification of a σ2 Receptor Agonist (BS148) with Selective Toxicity against Metastatic Melanoma 109
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 109
Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands 109
Substituted 1-phenyl-2-cyclopropylmethylamines with high affinity and selectivity for sigma sites 109
Effects of a Selective Sigma 1 Antagonist Compound on Inflammatory Pain 108
In-vitro evaluation of a new benzomorphan-based ligand 107
Intrastriatal administration of sigma ligands inhibits basal dopamine release in vivo 106
A NOVEL MIMETIC OF OPIOID TYRAMINE ACTIVE CONFORMATION 104
Novel Sigma Receptor Ligands: Synthesis and Biological Profile 103
Evaluation of N-substitution in 6,7-benzomorphan compounds 102
CCB - A novel analog of MPCB with high binding affinity and specific kappa opioid receptor agonist 102
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives 102
Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation 102
Synthesis and in vitro opioid receptor studies on benzomorphan-based compounds: LP1, a potent and long-acting antinociceptive 101
Nonpeptide Analogues of Dynorphin A(1-8): Design, Synthesis, and Pharmacological Evaluation of k-Selective Agonists 100
Evaluation of (–)-MR22 a novel sigma-1 receptor ligand on lesion-induced memory dysfunctions in the rat 100
Synthesis and biological characterization of 3-substituted-1H-indoles as ligands of GluN2B-containing N-methyl-D-aspartate receptors. 99
Pain management: new long-acting opioid ligands 99
Synthesis and spasmolytic action of 2-substituted thienopyrimidin-4-one derivatives 98
The multitarget opioid ligand LP1's effects in persistent pain and in primary cell neuronal cultures 98
New developments in opioid receptors ligands 97
From agonist to antagonist profile in LP1 analogues through the introduction of different N-substituents in benzomorphan-based ligands 96
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 94
Specific κ opioid receptor agonists 93
Synthesis of (+) and (−)-cis-2-[(1-adamantylamino)-methyl]-1-phenylcyclopropane derivatives as probe for sigma-1 and sigma-2 binding sites 92
DISCOVERY OF NEW SIGMA-2 RECEPTOR AGONIST ENDOWED WITH ANTIPROLIFERATIVE ACTIVITY 90
NOVEL 1-PHENYL-2-{[(2,6,6-TRIMETHYLBICYCLO[3.1.1]HEPT-3-YL)AMINO]METHYL}CYCLOPROPANECARBOXYLATE DIASTEREOISOMERS AS POTENT AND ENANTIOSELECTIVE SIGMA-1 AND SIGMA-2 LIGANDS 89
Synthesis of MRJF4 enentiomers and evaluation of proapoptotic and cytotoxic effects in cancer cell lines 89
Synthesis of (+)- and (-)-cis-2-[(1-adamantylamino)-methyl]-1-phenylcyclopropane derivatives as high affinity probes for sigma1 and sigma2 binding sites 89
Opioid and sigma receptor studies. New developments in the design of selective sigma ligands 88
New benzomorphan derivatives of MPCB as MOP and KOP receptor ligands 88
Modulation of opioid receptor profile of LP1 analogues through the introduction of different N-substituents 87
Benzyl-tropanyl esters and ethers of phenoxypropionic acid as novel sigma receptor ligands 86
Opioid multiple ligands 86
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 86
Role of the Nrf2/HO-1 axis in bronchopulmonary dysplasia and hyperoxic lung injuries 86
Synthesis and pharmacological evaluation of potent and enantioselective sigma-1 and sigma-2 ligands 86
Sigma receptor binding profile of a series of analgesic tropane derivatives 86
Recent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents 85
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 85
Effect of sigma ligands, (+)-MR200 anf (-)-MRV3, on DMPC biomembrane model: DSC study 85
Multitarget MOR/DOR antinociceptive ligands as useful profile in pain management: synthesis and pharmacological studies of 6,7-benzomorphan-based LP2 and its isomers 85
Novel methyl-2-[4-[(4-hydroxy-4-phenylpiperidin-1-yl)methyl]-1-phenylcyclopropane-carboxylate derivatives as sigma-1 and sigma-2 receptor ligands 82
New bifunctional antioxidant/σ1 agonist ligands: preliminary chemico-physical and biological evaluation 81
Totale 12.814
Salva come PNG Salva come JPEG
Categoria #
all - tutte 51.570
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 51.570
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021234 0 0 0 0 0 0 0 0 0 0 120 114
2021/20221.161 141 154 22 17 182 17 178 34 89 13 30 284
2022/20232.096 185 138 24 274 190 351 0 351 483 16 60 24
2023/2024963 51 199 32 29 41 247 15 65 0 22 180 82
2024/20253.276 34 618 163 237 638 337 203 159 233 250 195 209
2025/20266.219 406 197 1.307 390 989 1.269 711 112 378 367 93 0
Totale 16.162