IRIS
TURNATURI, RITA
 Distribuzione geografica
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Continente #
NA - Nord America 1.853
EU - Europa 1.180
AF - Africa 257
AS - Asia 251
OC - Oceania 5
SA - Sud America 4
Continente sconosciuto - Info sul continente non disponibili 1
Totale 3.551
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Nazione #
US - Stati Uniti d'America 1.806
IT - Italia 538
IE - Irlanda 236
CN - Cina 189
CI - Costa d'Avorio 172
UA - Ucraina 106
DE - Germania 95
SN - Senegal 80
RU - Federazione Russa 61
CA - Canada 47
FR - Francia 40
BE - Belgio 17
GB - Regno Unito 17
SE - Svezia 16
VN - Vietnam 15
ES - Italia 14
SG - Singapore 14
IN - India 11
AT - Austria 7
JP - Giappone 7
AU - Australia 5
FI - Finlandia 5
GR - Grecia 5
HU - Ungheria 5
NL - Olanda 5
PL - Polonia 5
EG - Egitto 3
PK - Pakistan 3
UZ - Uzbekistan 3
BG - Bulgaria 2
CL - Cile 2
HK - Hong Kong 2
IL - Israele 2
LB - Libano 2
NG - Nigeria 2
TR - Turchia 2
CH - Svizzera 1
CO - Colombia 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
EU - Europa 1
KZ - Kazakistan 1
NO - Norvegia 1
PE - Perù 1
PT - Portogallo 1
SI - Slovenia 1
Totale 3.551
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Città #
Houston 486
Chandler 466
Dublin 234
Abidjan 172
Catania 149
Ashburn 98
Jacksonville 84
Dakar 80
Bremen 64
Andover 63
Cambridge 62
Lawrence 62
Nanjing 58
Boardman 35
Des Moines 34
Toronto 34
Rome 30
Wilmington 29
Brussels 16
Shenyang 16
Messina 15
Saint Petersburg 15
Dong Ket 13
Jiaxing 13
Beijing 12
Changsha 11
Nanchang 11
San Mateo 11
Falls Church 10
Moscow 10
Ottawa 10
Pune 9
Tianjin 9
Grafing 8
Madrid 8
Jinan 7
Milan 7
Siracusa 7
Washington 7
Fukuoka 6
Hebei 6
Lentini 6
Ningbo 6
Rimini 6
San Giovanni la Punta 6
San Gregorio di Catania 6
Vittoria 6
Bologna 5
Budapest 5
Dearborn 5
Froges 5
Heidelberg 5
Marseille 5
Naples 5
Norwalk 5
Seattle 5
Aci Catena 4
Civitavecchia 4
Fremont 4
Groningen 4
Los Angeles 4
Melbourne 4
Misterbianco 4
New York 4
Paris 4
Pozzo Di Gotto 4
San Francisco 4
Tappahannock 4
Augusta 3
Bari 3
Benevento 3
Cagliari 3
Camerino 3
Casagiove 3
Chioggia 3
Gravina di Catania 3
Hanover 3
Helsinki 3
Kunming 3
Lahore 3
Modica 3
Pace 3
Providence 3
Randazzo 3
Reggio Calabria 3
Riposto 3
Scicli 3
Terrassa 3
Trieste 3
Valencia 3
Villamagna 3
Zhengzhou 3
Abuja 2
Agrate Brianza 2
Ann Arbor 2
Belpasso 2
Cairo 2
Central 2
Cergy 2
Edinburgh 2
Totale 2.694
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Nome #
Simultaneous targeting of MOR/DOR: A useful strategy for inflammatory pain modulation 353
((2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist 172
Neuroprotective effects of Rosmarinus officinalis L. extract in oxygen glucose deprivation (OGD)-injured human neural-like cells 99
Influenza del N-sostituente della (–)-cis-N-Normetazocina nella modulazione del profilo funzionale al MOR, DOR e KOR: da agonista ad antagonista attraverso ligandi misti agonisti/antagonisti 98
Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application 87
Exploiting the Power of Stereochemistry in Drug Action: 3-[(2S,6S,11S)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide as Potent Sigma-1 Receptor Antagonist 78
Design, synthesis, in vitro evaluation, and molecular modeling studies of N-substituted benzomorphans, analogs of LP2, as novel MOR ligands 73
LP2 e 2S-LP2: agonisti biased dual target MOR/DOR nel trattamento del dolore cronico 72
R- ed S-LP2: sintesi, molecular docking e valutazione farmacologica 67
Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists 65
In Vitro Antioxidant Activity and In Vivo Topical Efficacy of Lipid Nanoparticles Co-Loading Idebenone and Tocopheryl Acetate 64
Intercellular communication and ion channels in neuropathic pain chronicization 61
Development of novel LP1-based analogues with enhanced delta opioid receptor profile 60
Benzomorphan skeleton, a versatile scaffold for different targets: A comprehensive review 60
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 60
The benzomorphan-based LP1 ligand is a suitable MOR/DOR agonist for chronic pain treatment 58
Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: Design, synthesis, and pharmacological evaluation 57
Antinociceptive profile of LP1, a non-peptide multitarget opioid ligand. 54
(+)-and (−)-Phenazocine enantiomers: evaluation of their dual opioid agonist/σ1 antagonist properties and antinociceptive effects 53
MOR/DOR targeting: an useful strategy in pain management 53
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 52
Design and synthesis of trans-decahydroisoquinoline derivatives as new tramadol-like ligands 51
Dual MOR/DOR agonist benzomorphan-based compounds for pain relief 51
Haloperidol Metabolite II Valproate Ester (S)-(-)-MRJF22: Preliminary Studies as a Potential Multifunctional Agent Against Uveal Melanoma 51
Repeated activation of delta opiod receptors counteracts nerve injury-induced TNF-α up-regulation in the sciatic nerve of rats with neuropathic pain: A possible correlation with delta opiod receptors-mediated antiallodinic effect. 50
Evaluation of N-substituent structural variations in opioid receptor profile of LP1. 50
THE BENZOMORPHAN-BASED COMPOUND LP1 AS A MULTITARGET OPIOID LIGAND FOR CHRONIC PAIN TREATMENT 49
Multitarget opioid ligands in pain relief: New players in an old game 48
ANTIALLODINIC AND ANTIHYPERALGESIC EFFECTS OF LP1, AN OPIOID MULTITARGET LIGAND, IN INFLAMMATORY AND NEUROPATHIC PAIN STATES 48
Multitarget Opioid/Non-opioid Ligands: A Potential Approach in Pain Management 48
The Benzomorphan-Based Compound LP1 as Suitable Candidate for Pain Management 48
Differential scanning calorimetry approach to investigate the transfer of the multitarget opioid analgesic LP1 to biomembrane model 48
A structure-and ligand-based virtual screening of a database of “small” marine natural products for the identification of “blue” sigma-2 receptor ligands 48
Antiproliferative and Antioxidant Activity of Glycoconjugates of Dithiocarbamates and Their Copper(II) and Zinc(II) Complexes 47
Biotin-8-hydroxyquinoline conjugates and their metal complexes: Exploring the chemical properties and the antioxidant activity 47
Synthesis and Structure-Activity Relationships of LP1 Derivatives: N-Methyl-N-phenylethylamino Analogues as Novel MOR Agonists 47
From agonist to antagonist profile in LP1 analogues through the introduction of different N-substituents in benzomorphan-based ligands 46
The Multimodal MOPr/DOPr Agonist LP2 Reduces Allodynia in Chronic Constriction Injured Rats by Rescue of TGF-β1 Signalling 46
New selective Sigma-1/HDACi prodrugs for neurodegenerative disorders 45
Rosemary Essential Oil-Loaded Lipid Nanoparticles: In Vivo Topical Activity from Gel Vehicles 44
Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review 44
MOR/DOR targeting: an useful strategy in pain management 44
Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain 44
The multitarget opioid ligand LP1's effects in persistent pain and in primary cell neuronal cultures 41
Progress in the development of more effective and safer analgesics for pain management 41
Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation 41
Modulation of opioid receptor profile of LP1 analogues through the introduction of different N-substituents 39
A new Sigma-1 Receptor antagonist in Chronic Pain Treatment: (+)-2R/S-LP2 effects in inflammatory and neuropathic pain 38
Synthesis and structure-activity relationships of (–)-cis-N-normetazocine-based LP1 derivatives 37
Resveratrol-loaded lipid nanocarriers: Correlation between in vitro occlusion factor and in vivo skin hydrating effect 36
From plant to bench: natural products as source for analgesic drug development. 36
Simultaneous activation of mu and delta opioid receptors reduces allodynia and astrocytic connexin 43 in an animal model of neuropathic pain 36
Design, synthesis and biological evaluation of novel aminopropylcarboxamide derivatives as sigma ligands 35
The benzomorphan-based compound LP1 is a central acting MOR agonist/DOR antagonist suitable for chronic pain treatment 35
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 35
Synthesis and structure-activity relationships of (-)-cis-N-Normetazocine-based LP1 derivatives. MOR/DOR targeting mediates neuropathic pain amelioration in chronic constriction injured rats. 35
MOR/DOR targeting mediates neuropathic pain amelioration in chronic constriction injured rats. 35
Idebenone: Novel strategies to improve its systemic and local efficacy 34
Mu and Delta Opioid Receptor Targeting Reduces Connexin 43-Based Heterocellular Coupling during Neuropathic Pain 31
In Vitro Evaluation of Sunscreen Safety: Effects of the Vehicle and Repeated Applications on Skin Permeation from Topical Formulations 31
Design, synthesis, and biological evaluation of new hybrid MOR agonist/HDACi compounds: an innovative approach for persistent pain management 29
THE BENZOMORPHAN-BASED LP1 IS A CENTRAL-ACTING MULTITARGET OPIOID LIGAND FOR CHRONIC PAIN TREATMENT 28
Multitarget MOR/DOR antinociceptive ligands as useful profile in pain management: synthesis and pharmacological studies of 6,7-benzomorphan-based LP2 and its isomers 28
Sigma-1 Receptor Inhibition Reduces Mechanical Allodynia and Modulate Neuroinflammation in Chronic Neuropathic Pain 27
Tuning Properties for Blood-Brain Barrier Permeation: A Statistics-Based Analysis 26
IDEBENONE LOADED LIPID NANOPARTICLES: EVALUATION OF IN VITRO ANTIOXIDANT ACTIVITY AND IN VIVO TOPICAL EFFECTS 24
Solid lipid nanoparticles as carriers for the synthetic opioid lp2: Characterization and in vitro release 24
Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain 23
Hybrid MOR agonist/HDACi molecules as potential antinociceptive multi-target drugs: design, synthesis, and biological evaluation 21
NEW BENZOMORPHAN-BASED LP1 LIGAND AS SUITABLE MIXED MOP/DOP RECEPTORS AGONIST FOR CHRONIC PAIN TREATMENT 18
Design, Synthesis and biological evaluation of hybrid MOR agonist/ HDACi molecules as potential therapeutic agents for chronic pain treatment 17
Design, synthesis and biological evaluation of MOR agonist/HDACi hybrid compounds: a new potential therapeutic strategy for persistent pain management 16
MOR/DOR Dual-Target Approach: 2S-LP2 Effects in Inflammatory and Neuropathic Pain 16
Hybrid MOR agonist/HDACi molecules as potential new drugs for persistant pain management: design, synthesis and biological evaluation 12
New Insights into the Opioid Analgesic Profile of cis-(-)-N-Normetazocine-derived Ligands 9
From Plant to Chemistry: Sources of Antinociceptive Non-Opioid Active Principles for Medicinal Chemistry and Drug Design 8
From Plant to Chemistry: Sources of Active Opioid Antinociceptive Principles for Medicinal Chemistry and Drug Design 6
CO2-derived non-isocyanate polyurethanes (NIPUs) and their potential applications 5
NEW PLAYERS IN AN OLD GAME: Pharmacological Evaluation of the Benzomorphan-Based Compound LP1. Design and Synthesis of Conformationally Constrained Compounds as New Tramadol-like Candidates. 5
Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics for Pain Treatment 4
Correction to Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 3
Discovery of a novel series of potent carbonic anhydrase inhibitors with selective affinity for μ Opioid receptor for Safer and long-lasting analgesia 2
Totale 3.807
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Categoria #
all - tutte 10.835
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 10.835
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019167 0 0 0 0 0 0 0 0 0 5 27 135
2019/2020666 139 61 102 94 99 18 27 14 16 47 33 16
2020/2021362 13 17 36 21 95 13 42 6 36 12 40 31
2021/2022559 43 61 11 17 84 10 75 25 42 24 20 147
2022/20231.277 92 81 33 197 101 170 7 256 225 30 53 32
2023/2024585 34 108 43 32 55 197 37 55 2 22 0 0
Totale 3.807