IRIS
TURNATURI, RITA
 Distribuzione geografica
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Continente #
NA - Nord America 4.146
EU - Europa 1.616
AS - Asia 1.327
AF - Africa 336
SA - Sud America 279
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 1
Totale 7.710
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Nazione #
US - Stati Uniti d'America 4.072
IT - Italia 872
SG - Singapore 587
CN - Cina 500
BR - Brasile 247
CI - Costa d'Avorio 233
IE - Irlanda 232
DE - Germania 122
UA - Ucraina 113
SN - Senegal 79
KR - Corea 73
RU - Federazione Russa 67
CA - Canada 61
FR - Francia 40
GB - Regno Unito 31
JP - Giappone 29
ES - Italia 24
VN - Vietnam 23
FI - Finlandia 21
IN - India 19
SE - Svezia 17
BE - Belgio 15
PL - Polonia 14
HK - Hong Kong 13
ID - Indonesia 13
TR - Turchia 12
IQ - Iraq 11
BD - Bangladesh 10
MX - Messico 10
NL - Olanda 10
AR - Argentina 9
CZ - Repubblica Ceca 9
AT - Austria 8
UZ - Uzbekistan 8
PK - Pakistan 7
EC - Ecuador 6
ZA - Sudafrica 6
AU - Australia 5
GR - Grecia 5
HU - Ungheria 5
TN - Tunisia 5
VE - Venezuela 5
AE - Emirati Arabi Uniti 4
CO - Colombia 4
EG - Egitto 4
LB - Libano 4
LT - Lituania 4
MA - Marocco 4
BG - Bulgaria 3
IL - Israele 3
PY - Paraguay 3
SA - Arabia Saudita 3
CL - Cile 2
DO - Repubblica Dominicana 2
KE - Kenya 2
KZ - Kazakistan 2
NG - Nigeria 2
UY - Uruguay 2
AZ - Azerbaigian 1
BB - Barbados 1
CH - Svizzera 1
DK - Danimarca 1
DZ - Algeria 1
EU - Europa 1
GE - Georgia 1
IR - Iran 1
NO - Norvegia 1
NP - Nepal 1
OM - Oman 1
PE - Perù 1
PS - Palestinian Territory 1
PT - Portogallo 1
Totale 7.710
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Città #
Dallas 1.094
Santa Clara 491
Houston 486
Chandler 451
Singapore 338
Catania 248
Abidjan 233
Dublin 230
Chicago 219
Ashburn 134
Hefei 127
Boardman 115
Jacksonville 85
Beijing 79
Dakar 79
Seoul 73
Civitanova Marche 70
Bremen 62
Andover 61
Cambridge 60
Lawrence 60
Nanjing 57
Council Bluffs 49
Rome 38
Naples 36
The Dalles 35
Columbus 34
Des Moines 33
Toronto 33
Los Angeles 28
Wilmington 28
Munich 26
São Paulo 22
Tokyo 22
Messina 19
New York 19
San Giovanni la Punta 18
Shenyang 16
Brussels 14
Saint Petersburg 14
Changsha 13
Dong Ket 13
Jiaxing 12
Moscow 12
Paternò 12
Salerno 12
Hong Kong 11
Jakarta 11
San Mateo 11
Falls Church 10
Nanchang 10
Ottawa 10
Turku 10
Pune 9
Rimini 9
Tianjin 9
Grafing 8
Madrid 8
Milan 8
Pozzallo 8
Warsaw 8
Bologna 7
Brno 7
Brooklyn 7
Cagliari 7
Jinan 7
Lappeenranta 7
Rio de Janeiro 7
Siracusa 7
Washington 7
Aci Catena 6
Baghdad 6
Belo Horizonte 6
Fortaleza 6
Fukuoka 6
Hebei 6
Lentini 6
Montreal 6
Ningbo 6
Palermo 6
San Francisco 6
San Gregorio di Catania 6
Seattle 6
Vittoria 6
Atlanta 5
Budapest 5
Dearborn 5
Froges 5
Gravina di Catania 5
Heidelberg 5
London 5
Marseille 5
Misterbianco 5
Norwalk 5
Paris 5
Phoenix 5
Randazzo 5
Tashkent 5
Amsterdam 4
Bari 4
Totale 5.775
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Nome #
From Plant to Chemistry: Sources of Active Opioid Antinociceptive Principles for Medicinal Chemistry and Drug Design 429
Simultaneous targeting of MOR/DOR: A useful strategy for inflammatory pain modulation 390
((2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist 265
Neuroprotective effects of Rosmarinus officinalis L. extract in oxygen glucose deprivation (OGD)-injured human neural-like cells 154
Design, synthesis, in vitro evaluation, and molecular modeling studies of N-substituted benzomorphans, analogs of LP2, as novel MOR ligands 148
(+)-and (−)-Phenazocine enantiomers: evaluation of their dual opioid agonist/σ1 antagonist properties and antinociceptive effects 132
Influenza del N-sostituente della (–)-cis-N-Normetazocina nella modulazione del profilo funzionale al MOR, DOR e KOR: da agonista ad antagonista attraverso ligandi misti agonisti/antagonisti 131
Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application 125
A new Sigma-1 Receptor antagonist in Chronic Pain Treatment: (+)-2R/S-LP2 effects in inflammatory and neuropathic pain 124
Benzomorphan skeleton, a versatile scaffold for different targets: A comprehensive review 123
Exploiting the Power of Stereochemistry in Drug Action: 3-[(2S,6S,11S)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide as Potent Sigma-1 Receptor Antagonist 120
R- ed S-LP2: sintesi, molecular docking e valutazione farmacologica 116
Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists 111
Haloperidol Metabolite II Valproate Ester (S)-(-)-MRJF22: Preliminary Studies as a Potential Multifunctional Agent Against Uveal Melanoma 110
Antinociceptive profile of LP1, a non-peptide multitarget opioid ligand. 107
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 107
A structure-and ligand-based virtual screening of a database of “small” marine natural products for the identification of “blue” sigma-2 receptor ligands 106
ANTIALLODINIC AND ANTIHYPERALGESIC EFFECTS OF LP1, AN OPIOID MULTITARGET LIGAND, IN INFLAMMATORY AND NEUROPATHIC PAIN STATES 105
LP2 e 2S-LP2: agonisti biased dual target MOR/DOR nel trattamento del dolore cronico 105
Synthesis and Structure-Activity Relationships of LP1 Derivatives: N-Methyl-N-phenylethylamino Analogues as Novel MOR Agonists 103
From plant to bench: natural products as source for analgesic drug development. 103
Intercellular communication and ion channels in neuropathic pain chronicization 103
The Multimodal MOPr/DOPr Agonist LP2 Reduces Allodynia in Chronic Constriction Injured Rats by Rescue of TGF-β1 Signalling 102
Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review 99
In Vitro Antioxidant Activity and In Vivo Topical Efficacy of Lipid Nanoparticles Co-Loading Idebenone and Tocopheryl Acetate 99
Development of novel LP1-based analogues with enhanced delta opioid receptor profile 98
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 98
Antiproliferative and Antioxidant Activity of Glycoconjugates of Dithiocarbamates and Their Copper(II) and Zinc(II) Complexes 97
Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: Design, synthesis, and pharmacological evaluation 97
Design, synthesis and biological evaluation of novel aminopropylcarboxamide derivatives as sigma ligands 95
Tuning Properties for Blood-Brain Barrier Permeation: A Statistics-Based Analysis 92
The benzomorphan-based LP1 ligand is a suitable MOR/DOR agonist for chronic pain treatment 91
Sigma-1 Receptor Inhibition Reduces Mechanical Allodynia and Modulate Neuroinflammation in Chronic Neuropathic Pain 90
Mu and Delta Opioid Receptor Targeting Reduces Connexin 43-Based Heterocellular Coupling during Neuropathic Pain 90
Dual MOR/DOR agonist benzomorphan-based compounds for pain relief 90
Biotin-8-hydroxyquinoline conjugates and their metal complexes: Exploring the chemical properties and the antioxidant activity 90
CO2-derived non-isocyanate polyurethanes (NIPUs) and their potential applications 89
Multitarget opioid ligands in pain relief: New players in an old game 89
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 88
Design, synthesis, and biological evaluation of new hybrid MOR agonist/HDACi compounds: an innovative approach for persistent pain management 87
MOR/DOR targeting: an useful strategy in pain management 87
Design and synthesis of trans-decahydroisoquinoline derivatives as new tramadol-like ligands 86
Multitarget Opioid/Non-opioid Ligands: A Potential Approach in Pain Management 86
The benzomorphan-based compound LP1 is a central acting MOR agonist/DOR antagonist suitable for chronic pain treatment 85
Evaluation of N-substituent structural variations in opioid receptor profile of LP1. 85
The Benzomorphan-Based Compound LP1 as Suitable Candidate for Pain Management 84
New selective Sigma-1/HDACi prodrugs for neurodegenerative disorders 83
Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain 82
Rosemary Essential Oil-Loaded Lipid Nanoparticles: In Vivo Topical Activity from Gel Vehicles 79
Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain 78
Repeated activation of delta opiod receptors counteracts nerve injury-induced TNF-α up-regulation in the sciatic nerve of rats with neuropathic pain: A possible correlation with delta opiod receptors-mediated antiallodinic effect. 78
Differential scanning calorimetry approach to investigate the transfer of the multitarget opioid analgesic LP1 to biomembrane model 78
Progress in the development of more effective and safer analgesics for pain management 78
Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation 78
Analgesici oppioidi 75
New Insights into the Opioid Analgesic Profile of cis-(-)-N-Normetazocine-derived Ligands 74
THE BENZOMORPHAN-BASED COMPOUND LP1 AS A MULTITARGET OPIOID LIGAND FOR CHRONIC PAIN TREATMENT 74
From agonist to antagonist profile in LP1 analogues through the introduction of different N-substituents in benzomorphan-based ligands 74
The multitarget opioid ligand LP1's effects in persistent pain and in primary cell neuronal cultures 73
Synthesis and structure-activity relationships of (–)-cis-N-normetazocine-based LP1 derivatives 72
Correction to Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 71
Idebenone: Novel strategies to improve its systemic and local efficacy 71
From Plant to Chemistry: Sources of Antinociceptive Non-Opioid Active Principles for Medicinal Chemistry and Drug Design 70
Design, Synthesis and biological evaluation of hybrid MOR agonist/ HDACi molecules as potential therapeutic agents for chronic pain treatment 68
Resveratrol-loaded lipid nanocarriers: Correlation between in vitro occlusion factor and in vivo skin hydrating effect 68
Hybrid MOR agonist/HDACi molecules as potential antinociceptive multi-target drugs: design, synthesis, and biological evaluation 66
Dual-target ligands and pain: our experience 66
Modulation of opioid receptor profile of LP1 analogues through the introduction of different N-substituents 66
Simultaneous activation of mu and delta opioid receptors reduces allodynia and astrocytic connexin 43 in an animal model of neuropathic pain 65
Design, synthesis and biological evaluation of MOR agonist/HDACi hybrid compounds: a new potential therapeutic strategy for persistent pain management 63
Multitarget MOR/DOR antinociceptive ligands as useful profile in pain management: synthesis and pharmacological studies of 6,7-benzomorphan-based LP2 and its isomers 63
Solid lipid nanoparticles as carriers for the synthetic opioid lp2: Characterization and in vitro release 60
Hybrid MOR agonist/HDACi molecules as potential new drugs for persistant pain management: design, synthesis and biological evaluation 58
Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics for Pain Treatment 57
IDEBENONE LOADED LIPID NANOPARTICLES: EVALUATION OF IN VITRO ANTIOXIDANT ACTIVITY AND IN VIVO TOPICAL EFFECTS 57
THE BENZOMORPHAN-BASED LP1 IS A CENTRAL-ACTING MULTITARGET OPIOID LIGAND FOR CHRONIC PAIN TREATMENT 56
In Vitro Evaluation of Sunscreen Safety: Effects of the Vehicle and Repeated Applications on Skin Permeation from Topical Formulations 55
Synthesis and structure-activity relationships of (-)-cis-N-Normetazocine-based LP1 derivatives 55
MOR/DOR Dual-Target Approach: 2S-LP2 Effects in Inflammatory and Neuropathic Pain 53
Efficient green solvent-free CO2/epoxide cycloaddition catalyzed by a β-cyclodextrin-imidazolium-based ionic liquid 49
Tetrazine–trans-cyclooctene ligation: Unveiling the chemistry and applications within the human body 48
NEW PLAYERS IN AN OLD GAME: Pharmacological Evaluation of the Benzomorphan-Based Compound LP1. Design and Synthesis of Conformationally Constrained Compounds as New Tramadol-like Candidates. 44
NEW BENZOMORPHAN-BASED LP1 LIGAND AS SUITABLE MIXED MOP/DOP RECEPTORS AGONIST FOR CHRONIC PAIN TREATMENT 39
Discovery of a novel series of potent carbonic anhydrase inhibitors with selective affinity for μ Opioid receptor for Safer and long-lasting analgesia 25
Totale 7.980
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Categoria #
all - tutte 25.160
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 25.160
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021284 0 0 0 21 93 13 41 6 35 10 34 31
2021/2022544 43 58 10 17 82 10 73 24 41 24 20 142
2022/20231.239 90 79 32 192 96 165 7 244 220 30 52 32
2023/2024721 33 102 43 32 53 193 35 55 2 23 106 44
2024/20252.298 53 340 113 188 442 307 187 97 125 143 150 153
2025/20261.817 313 225 1.245 34 0 0 0 0 0 0 0 0
Totale 7.980