IRIS
TURNATURI, RITA
 Distribuzione geografica
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Continente #
NA - Nord America 3.975
AS - Asia 1.816
EU - Europa 1.729
AF - Africa 353
SA - Sud America 314
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 1
Totale 8.193
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Nazione #
US - Stati Uniti d'America 3.889
SG - Singapore 915
IT - Italia 879
CN - Cina 578
BR - Brasile 273
CI - Costa d'Avorio 232
IE - Irlanda 232
RU - Federazione Russa 136
DE - Germania 123
UA - Ucraina 114
SN - Senegal 79
KR - Corea 73
VN - Vietnam 72
CA - Canada 65
GB - Regno Unito 43
FR - Francia 41
JP - Giappone 35
IN - India 28
ES - Italia 27
FI - Finlandia 21
SE - Svezia 21
PL - Polonia 19
HK - Hong Kong 18
MX - Messico 18
NL - Olanda 18
TR - Turchia 16
BE - Belgio 15
AR - Argentina 14
ID - Indonesia 14
IQ - Iraq 12
ZA - Sudafrica 11
BD - Bangladesh 10
BJ - Benin 9
CZ - Repubblica Ceca 9
AE - Emirati Arabi Uniti 8
AT - Austria 8
PK - Pakistan 8
UZ - Uzbekistan 8
EC - Ecuador 6
LT - Lituania 6
TN - Tunisia 6
AU - Australia 5
CO - Colombia 5
EG - Egitto 5
GR - Grecia 5
HU - Ungheria 5
MA - Marocco 5
VE - Venezuela 5
CL - Cile 4
IL - Israele 4
LB - Libano 4
BG - Bulgaria 3
KE - Kenya 3
PY - Paraguay 3
SA - Arabia Saudita 3
DO - Repubblica Dominicana 2
IR - Iran 2
KZ - Kazakistan 2
NG - Nigeria 2
UY - Uruguay 2
AZ - Azerbaigian 1
BB - Barbados 1
CH - Svizzera 1
DK - Danimarca 1
DZ - Algeria 1
EU - Europa 1
GE - Georgia 1
NO - Norvegia 1
NP - Nepal 1
OM - Oman 1
PE - Perù 1
PS - Palestinian Territory 1
PT - Portogallo 1
SR - Suriname 1
TH - Thailandia 1
Totale 8.193
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Città #
Dallas 674
Singapore 502
Santa Clara 492
Houston 487
Chandler 451
Catania 250
Abidjan 232
Dublin 230
Chicago 221
Ashburn 178
Hefei 135
Boardman 115
Beijing 114
Jacksonville 85
Dakar 79
Seoul 73
Civitanova Marche 70
Bremen 62
Los Angeles 62
Andover 61
Cambridge 60
Lawrence 60
Nanjing 57
Council Bluffs 49
Rome 38
Naples 36
Moscow 35
The Dalles 35
Columbus 34
Buffalo 33
Des Moines 33
Toronto 33
New York 30
Tokyo 28
Wilmington 28
Munich 26
São Paulo 23
Messina 20
San Giovanni la Punta 18
Shenyang 16
Ho Chi Minh City 15
Hong Kong 15
Brussels 14
Saint Petersburg 14
Changsha 13
Dong Ket 13
Hanoi 13
Phoenix 13
Warsaw 13
Brooklyn 12
Jakarta 12
Jiaxing 12
Paternò 12
Salerno 12
Amsterdam 11
Denver 11
San Mateo 11
Falls Church 10
Nanchang 10
Ottawa 10
Turku 10
Cotonou 9
Milan 9
Montreal 9
Pune 9
Rimini 9
Tianjin 9
Atlanta 8
Grafing 8
London 8
Madrid 8
Pozzallo 8
Bologna 7
Brno 7
Cagliari 7
Fortaleza 7
Jinan 7
Lappeenranta 7
Orem 7
Rio de Janeiro 7
San Francisco 7
Seattle 7
Siracusa 7
Washington 7
Aci Catena 6
Baghdad 6
Belo Horizonte 6
Boston 6
Fukuoka 6
Hebei 6
Johannesburg 6
Lentini 6
Mexico City 6
Ningbo 6
Palermo 6
San Gregorio di Catania 6
Vittoria 6
Budapest 5
Chennai 5
Curitiba 5
Totale 5.792
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Nome #
Simultaneous targeting of MOR/DOR: A useful strategy for inflammatory pain modulation 396
((2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist 274
Neuroprotective effects of Rosmarinus officinalis L. extract in oxygen glucose deprivation (OGD)-injured human neural-like cells 173
Design, synthesis, in vitro evaluation, and molecular modeling studies of N-substituted benzomorphans, analogs of LP2, as novel MOR ligands 160
Benzomorphan skeleton, a versatile scaffold for different targets: A comprehensive review 146
(+)-and (−)-Phenazocine enantiomers: evaluation of their dual opioid agonist/σ1 antagonist properties and antinociceptive effects 143
Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application 137
Influenza del N-sostituente della (–)-cis-N-Normetazocina nella modulazione del profilo funzionale al MOR, DOR e KOR: da agonista ad antagonista attraverso ligandi misti agonisti/antagonisti 135
A new Sigma-1 Receptor antagonist in Chronic Pain Treatment: (+)-2R/S-LP2 effects in inflammatory and neuropathic pain 132
R- ed S-LP2: sintesi, molecular docking e valutazione farmacologica 130
Exploiting the Power of Stereochemistry in Drug Action: 3-[(2S,6S,11S)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide as Potent Sigma-1 Receptor Antagonist 129
Haloperidol Metabolite II Valproate Ester (S)-(-)-MRJF22: Preliminary Studies as a Potential Multifunctional Agent Against Uveal Melanoma 124
Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review 122
Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists 122
A structure-and ligand-based virtual screening of a database of “small” marine natural products for the identification of “blue” sigma-2 receptor ligands 121
ANTIALLODINIC AND ANTIHYPERALGESIC EFFECTS OF LP1, AN OPIOID MULTITARGET LIGAND, IN INFLAMMATORY AND NEUROPATHIC PAIN STATES 119
The Multimodal MOPr/DOPr Agonist LP2 Reduces Allodynia in Chronic Constriction Injured Rats by Rescue of TGF-β1 Signalling 118
Antinociceptive profile of LP1, a non-peptide multitarget opioid ligand. 116
Development of novel LP1-based analogues with enhanced delta opioid receptor profile 113
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 113
LP2 e 2S-LP2: agonisti biased dual target MOR/DOR nel trattamento del dolore cronico 112
Intercellular communication and ion channels in neuropathic pain chronicization 112
Design, synthesis and biological evaluation of novel aminopropylcarboxamide derivatives as sigma ligands 111
Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: Design, synthesis, and pharmacological evaluation 110
CO2-derived non-isocyanate polyurethanes (NIPUs) and their potential applications 108
Sigma-1 Receptor Inhibition Reduces Mechanical Allodynia and Modulate Neuroinflammation in Chronic Neuropathic Pain 108
Dual MOR/DOR agonist benzomorphan-based compounds for pain relief 108
Antiproliferative and Antioxidant Activity of Glycoconjugates of Dithiocarbamates and Their Copper(II) and Zinc(II) Complexes 108
Synthesis and Structure-Activity Relationships of LP1 Derivatives: N-Methyl-N-phenylethylamino Analogues as Novel MOR Agonists 107
In Vitro Antioxidant Activity and In Vivo Topical Efficacy of Lipid Nanoparticles Co-Loading Idebenone and Tocopheryl Acetate 107
From plant to bench: natural products as source for analgesic drug development. 107
MOR/DOR targeting: an useful strategy in pain management 106
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 104
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 104
Biotin-8-hydroxyquinoline conjugates and their metal complexes: Exploring the chemical properties and the antioxidant activity 102
Mu and Delta Opioid Receptor Targeting Reduces Connexin 43-Based Heterocellular Coupling during Neuropathic Pain 101
Design, synthesis, and biological evaluation of new hybrid MOR agonist/HDACi compounds: an innovative approach for persistent pain management 101
Design and synthesis of trans-decahydroisoquinoline derivatives as new tramadol-like ligands 99
Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain 99
The benzomorphan-based LP1 ligand is a suitable MOR/DOR agonist for chronic pain treatment 97
Tuning Properties for Blood-Brain Barrier Permeation: A Statistics-Based Analysis 97
Multitarget opioid ligands in pain relief: New players in an old game 96
New selective Sigma-1/HDACi prodrugs for neurodegenerative disorders 95
Multitarget Opioid/Non-opioid Ligands: A Potential Approach in Pain Management 94
The benzomorphan-based compound LP1 is a central acting MOR agonist/DOR antagonist suitable for chronic pain treatment 93
Evaluation of N-substituent structural variations in opioid receptor profile of LP1. 92
Correction to Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 91
New Insights into the Opioid Analgesic Profile of cis-(-)-N-Normetazocine-derived Ligands 90
Repeated activation of delta opiod receptors counteracts nerve injury-induced TNF-α up-regulation in the sciatic nerve of rats with neuropathic pain: A possible correlation with delta opiod receptors-mediated antiallodinic effect. 90
The Benzomorphan-Based Compound LP1 as Suitable Candidate for Pain Management 89
Progress in the development of more effective and safer analgesics for pain management 89
Dual-target ligands and pain: our experience 86
Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain 86
Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation 86
Rosemary Essential Oil-Loaded Lipid Nanoparticles: In Vivo Topical Activity from Gel Vehicles 85
Analgesici oppioidi 84
Differential scanning calorimetry approach to investigate the transfer of the multitarget opioid analgesic LP1 to biomembrane model 84
From Plant to Chemistry: Sources of Antinociceptive Non-Opioid Active Principles for Medicinal Chemistry and Drug Design 83
The multitarget opioid ligand LP1's effects in persistent pain and in primary cell neuronal cultures 83
Design, Synthesis and biological evaluation of hybrid MOR agonist/ HDACi molecules as potential therapeutic agents for chronic pain treatment 82
From agonist to antagonist profile in LP1 analogues through the introduction of different N-substituents in benzomorphan-based ligands 82
THE BENZOMORPHAN-BASED COMPOUND LP1 AS A MULTITARGET OPIOID LIGAND FOR CHRONIC PAIN TREATMENT 80
Hybrid MOR agonist/HDACi molecules as potential antinociceptive multi-target drugs: design, synthesis, and biological evaluation 79
Idebenone: Novel strategies to improve its systemic and local efficacy 79
Synthesis and structure-activity relationships of (–)-cis-N-normetazocine-based LP1 derivatives 79
Design, synthesis and biological evaluation of MOR agonist/HDACi hybrid compounds: a new potential therapeutic strategy for persistent pain management 75
Resveratrol-loaded lipid nanocarriers: Correlation between in vitro occlusion factor and in vivo skin hydrating effect 75
Efficient green solvent-free CO2/epoxide cycloaddition catalyzed by a β-cyclodextrin-imidazolium-based ionic liquid 72
Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics for Pain Treatment 72
Simultaneous activation of mu and delta opioid receptors reduces allodynia and astrocytic connexin 43 in an animal model of neuropathic pain 72
Hybrid MOR agonist/HDACi molecules as potential new drugs for persistant pain management: design, synthesis and biological evaluation 71
Modulation of opioid receptor profile of LP1 analogues through the introduction of different N-substituents 71
Solid lipid nanoparticles as carriers for the synthetic opioid lp2: Characterization and in vitro release 70
Multitarget MOR/DOR antinociceptive ligands as useful profile in pain management: synthesis and pharmacological studies of 6,7-benzomorphan-based LP2 and its isomers 69
Tetrazine–trans-cyclooctene ligation: Unveiling the chemistry and applications within the human body 66
IDEBENONE LOADED LIPID NANOPARTICLES: EVALUATION OF IN VITRO ANTIOXIDANT ACTIVITY AND IN VIVO TOPICAL EFFECTS 63
Synthesis and structure-activity relationships of (-)-cis-N-Normetazocine-based LP1 derivatives 62
THE BENZOMORPHAN-BASED LP1 IS A CENTRAL-ACTING MULTITARGET OPIOID LIGAND FOR CHRONIC PAIN TREATMENT 61
NEW PLAYERS IN AN OLD GAME: Pharmacological Evaluation of the Benzomorphan-Based Compound LP1. Design and Synthesis of Conformationally Constrained Compounds as New Tramadol-like Candidates. 61
In Vitro Evaluation of Sunscreen Safety: Effects of the Vehicle and Repeated Applications on Skin Permeation from Topical Formulations 60
MOR/DOR Dual-Target Approach: 2S-LP2 Effects in Inflammatory and Neuropathic Pain 60
NEW BENZOMORPHAN-BASED LP1 LIGAND AS SUITABLE MIXED MOP/DOP RECEPTORS AGONIST FOR CHRONIC PAIN TREATMENT 47
Discovery of a novel series of potent carbonic anhydrase inhibitors with selective affinity for μ Opioid receptor for Safer and long-lasting analgesia 27
Totale 8.462
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Categoria #
all - tutte 26.628
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 26.628
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021170 0 0 0 0 0 13 41 6 35 10 34 31
2021/2022544 43 58 10 17 82 10 73 24 41 24 20 142
2022/20231.239 90 79 32 192 96 165 7 244 220 30 52 32
2023/2024721 33 102 43 32 53 193 35 55 2 23 106 44
2024/20252.298 53 340 113 188 442 307 187 97 125 143 150 153
2025/20262.299 313 225 817 271 645 28 0 0 0 0 0 0
Totale 8.462