IRIS
TURNATURI, RITA
 Distribuzione geografica
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Continente #
NA - Nord America 2.767
EU - Europa 1.533
AS - Asia 837
AF - Africa 264
SA - Sud America 191
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5.598
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Nazione #
US - Stati Uniti d'America 2.715
IT - Italia 851
SG - Singapore 477
CN - Cina 268
IE - Irlanda 232
BR - Brasile 170
CI - Costa d'Avorio 167
DE - Germania 119
UA - Ucraina 108
SN - Senegal 79
RU - Federazione Russa 66
CA - Canada 47
FR - Francia 38
JP - Giappone 19
GB - Regno Unito 17
SE - Svezia 16
BE - Belgio 15
VN - Vietnam 15
ES - Italia 14
IN - India 12
FI - Finlandia 10
NL - Olanda 9
CZ - Repubblica Ceca 8
TR - Turchia 8
UZ - Uzbekistan 8
AT - Austria 7
PL - Polonia 6
AR - Argentina 5
AU - Australia 5
GR - Grecia 5
HU - Ungheria 5
TN - Tunisia 5
BD - Bangladesh 4
CO - Colombia 4
EC - Ecuador 4
EG - Egitto 4
HK - Hong Kong 4
MX - Messico 4
ZA - Sudafrica 4
AE - Emirati Arabi Uniti 3
BG - Bulgaria 3
IQ - Iraq 3
LB - Libano 3
PK - Pakistan 3
CL - Cile 2
IL - Israele 2
KZ - Kazakistan 2
MA - Marocco 2
NG - Nigeria 2
PY - Paraguay 2
VE - Venezuela 2
AZ - Azerbaigian 1
CH - Svizzera 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
EU - Europa 1
GE - Georgia 1
ID - Indonesia 1
IR - Iran 1
KE - Kenya 1
NO - Norvegia 1
OM - Oman 1
PE - Perù 1
PS - Palestinian Territory 1
PT - Portogallo 1
UY - Uruguay 1
Totale 5.598
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Città #
Houston 486
Santa Clara 479
Chandler 451
Singapore 252
Catania 243
Dublin 230
Chicago 214
Abidjan 167
Boardman 115
Ashburn 100
Jacksonville 84
Dakar 79
Civitanova Marche 70
Bremen 62
Andover 61
Cambridge 60
Lawrence 60
Nanjing 57
Rome 38
Naples 36
Council Bluffs 33
Des Moines 33
Toronto 33
Wilmington 28
Munich 24
Messina 18
San Giovanni la Punta 18
São Paulo 17
Beijing 16
Shenyang 16
Brussels 14
Saint Petersburg 14
Changsha 13
Dong Ket 13
Jiaxing 12
Moscow 12
Paternò 12
Salerno 12
Tokyo 12
San Mateo 11
Falls Church 10
Los Angeles 10
Nanchang 10
Ottawa 10
Pune 9
Rimini 9
Tianjin 9
Grafing 8
Madrid 8
Bologna 7
Brno 7
Cagliari 7
Jinan 7
Milan 7
Pozzallo 7
Siracusa 7
Washington 7
Aci Catena 6
Fukuoka 6
Hebei 6
Lappeenranta 6
Lentini 6
Ningbo 6
Palermo 6
Rio de Janeiro 6
San Gregorio di Catania 6
Vittoria 6
Budapest 5
Dearborn 5
Fortaleza 5
Froges 5
Gravina di Catania 5
Heidelberg 5
Marseille 5
Misterbianco 5
Norwalk 5
Randazzo 5
Seattle 5
Tashkent 5
Bari 4
Belo Horizonte 4
Bronte 4
Civitavecchia 4
Fremont 4
Groningen 4
Helsinki 4
Melbourne 4
New York 4
Paris 4
Pozzo Di Gotto 4
Tappahannock 4
Trieste 4
Amsterdam 3
Augusta 3
Benevento 3
Cairo 3
Camerino 3
Campinas 3
Casagiove 3
Chioggia 3
Totale 4.040
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Nome #
Simultaneous targeting of MOR/DOR: A useful strategy for inflammatory pain modulation 375
((2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist 207
Neuroprotective effects of Rosmarinus officinalis L. extract in oxygen glucose deprivation (OGD)-injured human neural-like cells 136
Design, synthesis, in vitro evaluation, and molecular modeling studies of N-substituted benzomorphans, analogs of LP2, as novel MOR ligands 120
Influenza del N-sostituente della (–)-cis-N-Normetazocina nella modulazione del profilo funzionale al MOR, DOR e KOR: da agonista ad antagonista attraverso ligandi misti agonisti/antagonisti 118
Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application 112
Exploiting the Power of Stereochemistry in Drug Action: 3-[(2S,6S,11S)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide as Potent Sigma-1 Receptor Antagonist 107
Synthesis and Structure-Activity Relationships of LP1 Derivatives: N-Methyl-N-phenylethylamino Analogues as Novel MOR Agonists 96
Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists 95
From plant to bench: natural products as source for analgesic drug development. 93
(+)-and (−)-Phenazocine enantiomers: evaluation of their dual opioid agonist/σ1 antagonist properties and antinociceptive effects 91
R- ed S-LP2: sintesi, molecular docking e valutazione farmacologica 89
Intercellular communication and ion channels in neuropathic pain chronicization 89
Haloperidol Metabolite II Valproate Ester (S)-(-)-MRJF22: Preliminary Studies as a Potential Multifunctional Agent Against Uveal Melanoma 88
LP2 e 2S-LP2: agonisti biased dual target MOR/DOR nel trattamento del dolore cronico 86
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 85
Development of novel LP1-based analogues with enhanced delta opioid receptor profile 84
In Vitro Antioxidant Activity and In Vivo Topical Efficacy of Lipid Nanoparticles Co-Loading Idebenone and Tocopheryl Acetate 84
The Multimodal MOPr/DOPr Agonist LP2 Reduces Allodynia in Chronic Constriction Injured Rats by Rescue of TGF-β1 Signalling 83
Benzomorphan skeleton, a versatile scaffold for different targets: A comprehensive review 81
The benzomorphan-based compound LP1 is a central acting MOR agonist/DOR antagonist suitable for chronic pain treatment 80
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 80
Tuning Properties for Blood-Brain Barrier Permeation: A Statistics-Based Analysis 80
The benzomorphan-based LP1 ligand is a suitable MOR/DOR agonist for chronic pain treatment 78
Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: Design, synthesis, and pharmacological evaluation 78
ANTIALLODINIC AND ANTIHYPERALGESIC EFFECTS OF LP1, AN OPIOID MULTITARGET LIGAND, IN INFLAMMATORY AND NEUROPATHIC PAIN STATES 76
Dual MOR/DOR agonist benzomorphan-based compounds for pain relief 74
Antinociceptive profile of LP1, a non-peptide multitarget opioid ligand. 74
A new Sigma-1 Receptor antagonist in Chronic Pain Treatment: (+)-2R/S-LP2 effects in inflammatory and neuropathic pain 73
Multitarget opioid ligands in pain relief: New players in an old game 72
A structure-and ligand-based virtual screening of a database of “small” marine natural products for the identification of “blue” sigma-2 receptor ligands 72
From agonist to antagonist profile in LP1 analogues through the introduction of different N-substituents in benzomorphan-based ligands 70
Multitarget Opioid/Non-opioid Ligands: A Potential Approach in Pain Management 70
Biotin-8-hydroxyquinoline conjugates and their metal complexes: Exploring the chemical properties and the antioxidant activity 70
Repeated activation of delta opiod receptors counteracts nerve injury-induced TNF-α up-regulation in the sciatic nerve of rats with neuropathic pain: A possible correlation with delta opiod receptors-mediated antiallodinic effect. 70
Evaluation of N-substituent structural variations in opioid receptor profile of LP1. 70
Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain 70
Design and synthesis of trans-decahydroisoquinoline derivatives as new tramadol-like ligands 69
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 69
New selective Sigma-1/HDACi prodrugs for neurodegenerative disorders 69
Mu and Delta Opioid Receptor Targeting Reduces Connexin 43-Based Heterocellular Coupling during Neuropathic Pain 68
The Benzomorphan-Based Compound LP1 as Suitable Candidate for Pain Management 68
Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review 68
Antiproliferative and Antioxidant Activity of Glycoconjugates of Dithiocarbamates and Their Copper(II) and Zinc(II) Complexes 67
Differential scanning calorimetry approach to investigate the transfer of the multitarget opioid analgesic LP1 to biomembrane model 67
Progress in the development of more effective and safer analgesics for pain management 67
MOR/DOR targeting: an useful strategy in pain management 66
THE BENZOMORPHAN-BASED COMPOUND LP1 AS A MULTITARGET OPIOID LIGAND FOR CHRONIC PAIN TREATMENT 65
Rosemary Essential Oil-Loaded Lipid Nanoparticles: In Vivo Topical Activity from Gel Vehicles 65
Design, synthesis and biological evaluation of novel aminopropylcarboxamide derivatives as sigma ligands 64
Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation 63
Design, synthesis, and biological evaluation of new hybrid MOR agonist/HDACi compounds: an innovative approach for persistent pain management 61
Modulation of opioid receptor profile of LP1 analogues through the introduction of different N-substituents 59
The multitarget opioid ligand LP1's effects in persistent pain and in primary cell neuronal cultures 59
Sigma-1 Receptor Inhibition Reduces Mechanical Allodynia and Modulate Neuroinflammation in Chronic Neuropathic Pain 57
Synthesis and structure-activity relationships of (–)-cis-N-normetazocine-based LP1 derivatives 56
Idebenone: Novel strategies to improve its systemic and local efficacy 55
Simultaneous activation of mu and delta opioid receptors reduces allodynia and astrocytic connexin 43 in an animal model of neuropathic pain 53
Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain 52
Resveratrol-loaded lipid nanocarriers: Correlation between in vitro occlusion factor and in vivo skin hydrating effect 51
Synthesis and structure-activity relationships of (-)-cis-N-Normetazocine-based LP1 derivatives 49
New Insights into the Opioid Analgesic Profile of cis-(-)-N-Normetazocine-derived Ligands 48
CO2-derived non-isocyanate polyurethanes (NIPUs) and their potential applications 46
In Vitro Evaluation of Sunscreen Safety: Effects of the Vehicle and Repeated Applications on Skin Permeation from Topical Formulations 45
Solid lipid nanoparticles as carriers for the synthetic opioid lp2: Characterization and in vitro release 45
Multitarget MOR/DOR antinociceptive ligands as useful profile in pain management: synthesis and pharmacological studies of 6,7-benzomorphan-based LP2 and its isomers 44
From Plant to Chemistry: Sources of Antinociceptive Non-Opioid Active Principles for Medicinal Chemistry and Drug Design 43
THE BENZOMORPHAN-BASED LP1 IS A CENTRAL-ACTING MULTITARGET OPIOID LIGAND FOR CHRONIC PAIN TREATMENT 42
Design, synthesis and biological evaluation of MOR agonist/HDACi hybrid compounds: a new potential therapeutic strategy for persistent pain management 41
IDEBENONE LOADED LIPID NANOPARTICLES: EVALUATION OF IN VITRO ANTIOXIDANT ACTIVITY AND IN VIVO TOPICAL EFFECTS 41
MOR/DOR Dual-Target Approach: 2S-LP2 Effects in Inflammatory and Neuropathic Pain 41
Dual-target ligands and pain: our experience 40
Design, Synthesis and biological evaluation of hybrid MOR agonist/ HDACi molecules as potential therapeutic agents for chronic pain treatment 40
Analgesici oppioidi 40
Hybrid MOR agonist/HDACi molecules as potential antinociceptive multi-target drugs: design, synthesis, and biological evaluation 37
Correction to Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents 34
Hybrid MOR agonist/HDACi molecules as potential new drugs for persistant pain management: design, synthesis and biological evaluation 32
NEW BENZOMORPHAN-BASED LP1 LIGAND AS SUITABLE MIXED MOP/DOP RECEPTORS AGONIST FOR CHRONIC PAIN TREATMENT 30
Discovery of a novel series of potent carbonic anhydrase inhibitors with selective affinity for μ Opioid receptor for Safer and long-lasting analgesia 24
NEW PLAYERS IN AN OLD GAME: Pharmacological Evaluation of the Benzomorphan-Based Compound LP1. Design and Synthesis of Conformationally Constrained Compounds as New Tramadol-like Candidates. 24
Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics for Pain Treatment 23
Efficient green solvent-free CO2/epoxide cycloaddition catalyzed by a β-cyclodextrin-imidazolium-based ionic liquid 20
Tetrazine–trans-cyclooctene ligation: Unveiling the chemistry and applications within the human body 18
From Plant to Chemistry: Sources of Active Opioid Antinociceptive Principles for Medicinal Chemistry and Drug Design 5
Totale 5.866
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Categoria #
all - tutte 19.658
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 19.658
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202049 0 0 0 0 0 0 0 0 0 0 33 16
2020/2021349 13 17 35 21 93 13 41 6 35 10 34 31
2021/2022544 43 58 10 17 82 10 73 24 41 24 20 142
2022/20231.239 90 79 32 192 96 165 7 244 220 30 52 32
2023/2024721 33 102 43 32 53 193 35 55 2 23 106 44
2024/20252.001 53 340 113 188 442 307 187 97 129 144 1 0
Totale 5.866