IRIS
PITTALA', Valeria
 Distribuzione geografica
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Continente #
NA - Nord America 9.121
EU - Europa 3.944
AS - Asia 3.527
SA - Sud America 814
AF - Africa 467
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 6
Totale 17.886
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Nazione #
US - Stati Uniti d'America 8.829
SG - Singapore 1.760
IT - Italia 1.483
CN - Cina 1.219
IE - Irlanda 808
BR - Brasile 740
UA - Ucraina 513
CI - Costa d'Avorio 349
DE - Germania 321
CA - Canada 253
RU - Federazione Russa 219
FI - Finlandia 142
GB - Regno Unito 105
VN - Vietnam 99
KR - Corea 92
IN - India 67
SN - Senegal 66
FR - Francia 64
JP - Giappone 47
SE - Svezia 46
PL - Polonia 43
ES - Italia 40
NL - Olanda 35
AT - Austria 32
HK - Hong Kong 31
BD - Bangladesh 30
UZ - Uzbekistan 30
IQ - Iraq 27
MX - Messico 26
ID - Indonesia 25
AR - Argentina 24
TR - Turchia 19
CZ - Repubblica Ceca 17
MA - Marocco 17
CH - Svizzera 16
EC - Ecuador 16
IR - Iran 16
VE - Venezuela 14
ZA - Sudafrica 13
GR - Grecia 10
BG - Bulgaria 9
LT - Lituania 9
PK - Pakistan 7
SA - Arabia Saudita 7
AE - Emirati Arabi Uniti 6
AU - Australia 6
BE - Belgio 6
CO - Colombia 6
EG - Egitto 6
IL - Israele 6
JO - Giordania 6
KE - Kenya 6
LB - Libano 6
NP - Nepal 6
EU - Europa 5
RO - Romania 5
TN - Tunisia 5
CL - Cile 4
JM - Giamaica 4
LU - Lussemburgo 4
PY - Paraguay 4
AZ - Azerbaigian 3
BY - Bielorussia 3
HU - Ungheria 3
MD - Moldavia 3
NG - Nigeria 3
OM - Oman 3
PE - Perù 3
PT - Portogallo 3
AL - Albania 2
GT - Guatemala 2
GY - Guiana 2
HN - Honduras 2
KW - Kuwait 2
MN - Mongolia 2
PA - Panama 2
PH - Filippine 2
PS - Palestinian Territory 2
TT - Trinidad e Tobago 2
BH - Bahrain 1
CY - Cipro 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
GE - Georgia 1
GN - Guinea 1
KG - Kirghizistan 1
LV - Lettonia 1
MT - Malta 1
MY - Malesia 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
SY - Repubblica araba siriana 1
TW - Taiwan 1
UY - Uruguay 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 17.886
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Città #
Dallas 1.878
Chandler 1.087
Singapore 909
Santa Clara 887
Dublin 806
Jacksonville 531
Chicago 440
Catania 393
Abidjan 349
Boardman 346
Ashburn 331
Houston 269
Cambridge 224
Lawrence 223
Andover 220
Nanjing 214
Munich 209
Beijing 200
Hefei 182
Toronto 177
Civitanova Marche 140
Des Moines 115
San Mateo 98
Wilmington 95
Helsinki 93
Seoul 91
Los Angeles 83
São Paulo 78
Nanchang 67
Council Bluffs 66
Dakar 66
Shenyang 60
Columbus 56
The Dalles 56
New York 49
Saint Petersburg 49
Rome 48
Naples 47
Hebei 46
Tokyo 46
Ottawa 43
Changsha 41
Jiaxing 41
Bremen 40
Tianjin 39
Ho Chi Minh City 37
Florence 36
Palermo 32
Milan 30
Redmond 30
Brooklyn 27
Hong Kong 26
Dong Ket 25
Belo Horizonte 24
Falls Church 24
Rio de Janeiro 24
Warsaw 24
Moscow 22
Turku 22
Pune 21
Washington 21
Messina 19
Phoenix 19
Jakarta 18
Redondo Beach 18
Seattle 18
Atlanta 17
Norwalk 17
Boydton 16
London 16
Brasília 15
Curitiba 15
Mumbai 15
Lappeenranta 14
Tashkent 14
Augusta 13
Buffalo 13
Civitavecchia 13
Guangzhou 13
Baghdad 12
Barcelona 12
Hanoi 12
Osio Sotto 12
Salerno 12
San Francisco 12
Aci Catena 11
Ann Arbor 11
Montreal 11
Orem 11
Tremestieri Etneo 11
Zhengzhou 11
Den Haag 10
Dhaka 10
Guarulhos 10
Johannesburg 10
Kunming 10
Manchester 10
Padova 10
Porto Alegre 10
Redwood City 10
Totale 12.464
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Nome #
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 247
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 243
Haloperidol drug repurposing unveils ferroptosis involvement in breast cancer cells 221
Antioxidant properties and pharmacokinetic studies of new selective σ1 bifunctional ligands 168
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 154
Design, synthesis, and pharmacological evaluation of NO donor-sigma receptors hybrids for the treatment of cancer 150
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 147
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 141
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 140
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 135
Heme Oxygenase Inhibition Sensitizes Neuroblastoma Cells to Carfilzomib 135
Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application 130
Heme Oxygenase-1 and Carbon Monoxide Regulate Growth and Progression in Glioblastoma Cells 127
A focus on Heme Oxygenase-1 (HO-1) inhibitors 121
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 120
(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties 119
Non-competitive heme oxygenase-1 activity inhibitor reduces non-small cell lung cancer glutathione content and regulates cell proliferation 116
Heme Oxygenase-1 Overexpression Promotes Uveal Melanoma Progression and Is Associated with Poor Clinical Outcomes 115
Effects of Novel Nitric Oxide-Releasing Molecules against Oxidative Stress on Retinal Pigmented Epithelial Cells 113
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 112
Synthetic cannabinoids nano-micelles for the management of triple negative breast cancer 112
Development of Sigma Receptors Nitric Oxide Photodonor Ligands with Antiproliferative Activity 110
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 110
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 109
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 109
(+)-cis-N-ethyleneamino-N-normetazocine derivatives. Novel and selective sigma ligands with antagonist properties 108
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 108
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 107
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 106
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 105
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 104
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 103
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 103
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 103
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 102
5-HT7 receptor ligands: recent developments and potential therapeutic applications 102
New arylethanolimidazole derivatives as HO-1 inhibitors with cytotoxicity against MCF-7 breast cancer cells 102
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 101
3-Amino-pyrrolo[3,4-c]pyrazole: Design and validation of a novel, highly versatile scaffold for kinase inhibition 100
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 100
The Effect of Silver Nanoparticles on Learning, Memory and Social Interaction in BALB/C Mice 100
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 99
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells 98
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 98
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 97
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 97
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 97
Combination of heme oxygenase-1 inhibitors and temozolomide to improve the anticancer effect in glioblastoma 96
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 95
Novel Acetamide-Based HO-1 Inhibitor Counteracts Glioblastoma Progression by Interfering with the Hypoxic–Angiogenic Pathway 94
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 94
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 94
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 94
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 93
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 93
Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands 93
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 93
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 93
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 91
Berberine-styrene-co-maleic acid nanomicelles: unlocking opportunities for the treatment and prevention of bacterial infections 90
Novel Sigma-1 receptor antagonists: From opioids to small molecules: What is new? 90
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 89
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 88
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 88
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 88
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 87
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 87
Nonpeptide Analogues of Dynorphin A(1-8): Design, Synthesis, and Pharmacological Evaluation of k-Selective Agonists 86
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 84
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 84
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 84
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 84
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 84
The analgesic potential of glycosides derived from medicinal plants 84
Novel indole derivatives targeting HuR-mRNA complex to counteract high glucose damage in retinal endothelial cells 84
Targeting STATs in neuroinflammation: The road less traveled! 83
Progress in the development of more effective and safer analgesics for pain management 83
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 82
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 82
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 82
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 82
Novel Sigma Receptors Ligands-Nitric Oxide Photodonor: Molecular Hybrids for Double-Targeted Antiproliferative Effect 82
Ginseng and heme oxygenase-1: The link between an old herb and a new protective system 82
HO-1 INHIBITION POTENTIATES METFORMIN ANTINEOPLASTIC EFFECTS IN HUMAN PROSTATE CANCER CELLS UNDER LOW GLUCOSE CONCENTRATION 82
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 82
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 81
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 80
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 80
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 80
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 80
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 79
3-Amino-pyrrolo[3,4-c]pyrazoles: A new class of CDK2 inhibitors 79
Analoghi non-peptidici della dinorfina A(1-8): progettazione, sintesi e valutazione farmacologica di agonisti ad elevata selettività Kappa. 78
Synthesis and experimental validation of new designed heterocyclic compounds with antiproliferative activity versus breast cancer cell lines MCF-7 and MDA-MB-231 78
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 76
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 76
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 76
Role of the Nrf2/HO-1 axis in bronchopulmonary dysplasia and hyperoxic lung injuries 76
Targeting the hydrophobic heme oxygenase-1 western region for the identification of novel and selective azole-based inhibitors. 76
Synthesis and Binding Properties of New Endothelin Receptor Ligands 75
Totale 10.240
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Categoria #
all - tutte 65.674
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 65.674
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021757 0 0 0 0 333 24 117 10 79 23 126 45
2021/20221.764 200 232 62 14 258 51 258 66 141 29 62 391
2022/20233.030 271 169 77 333 267 535 9 482 689 40 125 33
2023/20241.254 75 209 55 58 102 279 18 60 4 44 202 148
2024/20255.213 45 757 329 322 989 509 355 262 453 469 362 361
2025/20264.036 618 400 2.089 508 421 0 0 0 0 0 0 0
Totale 18.404