IRIS
PITTALA', Valeria
 Distribuzione geografica
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Continente #
NA - Nord America 11.652
EU - Europa 6.257
AS - Asia 5.483
SA - Sud America 1.025
AF - Africa 668
Continente sconosciuto - Info sul continente non disponibili 533
OC - Oceania 9
Totale 25.627
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Nazione #
US - Stati Uniti d'America 11.204
SG - Singapore 2.859
RU - Federazione Russa 1.804
IT - Italia 1.680
CN - Cina 1.394
BR - Brasile 850
IE - Irlanda 806
UA - Ucraina 519
VN - Vietnam 396
CI - Costa d'Avorio 350
DE - Germania 342
FR - Francia 329
CA - Canada 320
KR - Corea 180
FI - Finlandia 159
GB - Regno Unito 152
SE - Svezia 117
NG - Nigeria 116
IN - India 112
BD - Bangladesh 92
HK - Hong Kong 86
SN - Senegal 67
PL - Polonia 61
JP - Giappone 59
ES - Italia 56
MX - Messico 56
AR - Argentina 54
NL - Olanda 53
IQ - Iraq 49
UZ - Uzbekistan 39
AT - Austria 35
ZA - Sudafrica 35
ID - Indonesia 32
TR - Turchia 32
CO - Colombia 29
EC - Ecuador 27
VE - Venezuela 26
JM - Giamaica 25
KE - Kenya 25
MA - Marocco 24
PK - Pakistan 24
CZ - Repubblica Ceca 22
CH - Svizzera 17
IR - Iran 16
BJ - Benin 14
CL - Cile 14
GR - Grecia 14
LT - Lituania 14
AE - Emirati Arabi Uniti 11
EG - Egitto 11
JO - Giordania 11
NP - Nepal 11
SA - Arabia Saudita 11
AL - Albania 10
ET - Etiopia 10
BG - Bulgaria 9
CR - Costa Rica 9
PH - Filippine 9
AU - Australia 8
LB - Libano 8
TN - Tunisia 8
BE - Belgio 7
GT - Guatemala 7
MY - Malesia 7
OM - Oman 7
PY - Paraguay 7
BO - Bolivia 6
IL - Israele 6
PE - Perù 6
PT - Portogallo 6
RO - Romania 6
TT - Trinidad e Tobago 6
BY - Bielorussia 5
EU - Europa 5
HN - Honduras 5
HU - Ungheria 5
LV - Lettonia 5
MD - Moldavia 5
RS - Serbia 5
AZ - Azerbaigian 4
LU - Lussemburgo 4
PA - Panama 4
SY - Repubblica araba siriana 4
UY - Uruguay 4
DZ - Algeria 3
HR - Croazia 3
KG - Kirghizistan 3
KW - Kuwait 3
XK - ???statistics.table.value.countryCode.XK??? 3
BZ - Belize 2
DK - Danimarca 2
DM - Dominica 2
DO - Repubblica Dominicana 2
GA - Gabon 2
GE - Georgia 2
GY - Guiana 2
KZ - Kazakistan 2
MN - Mongolia 2
MT - Malta 2
NI - Nicaragua 2
Totale 25.075
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Città #
Dallas 1.903
Singapore 1.667
Chandler 1.083
Santa Clara 958
San Jose 875
Dublin 804
Moscow 771
Ashburn 631
Jacksonville 530
Chicago 459
Catania 408
Abidjan 350
Boardman 344
Houston 257
Council Bluffs 249
Beijing 223
Cambridge 223
Lawrence 223
Lauterbourg 221
Andover 219
Nanjing 215
Munich 209
Toronto 189
Hefei 182
Seoul 179
Los Angeles 176
Civitanova Marche 139
Ho Chi Minh City 128
Des Moines 116
New York 116
Helsinki 105
São Paulo 104
San Mateo 97
Wilmington 94
Rome 83
Hanoi 81
Hong Kong 75
Dakar 67
Nanchang 67
Buffalo 66
Shenyang 60
Columbus 56
Naples 56
The Dalles 55
Tokyo 54
Lagos 50
Orem 49
Palermo 49
Saint Petersburg 48
Hebei 46
Abuja 44
Milan 44
Ottawa 44
Changsha 43
Florence 41
Bremen 40
Jiaxing 40
Warsaw 40
Tianjin 39
Atlanta 37
Brooklyn 37
Phoenix 36
Montreal 33
Belo Horizonte 30
Redmond 30
Seattle 30
Rio de Janeiro 29
Dong Ket 25
Falls Church 24
Johannesburg 24
Mexico City 24
Stockholm 23
Port Harcourt 22
Tashkent 22
Turku 22
Amsterdam 21
Denver 21
London 21
Mumbai 21
Pune 21
Washington 21
Baghdad 20
Dhaka 20
Jakarta 20
Lappeenranta 19
Messina 19
Boydton 18
Da Nang 18
Manchester 18
Redondo Beach 18
Kingston 17
Norwalk 17
Brasília 16
San Francisco 16
Chennai 15
Curitiba 15
Frankfurt am Main 15
Paris 15
Poplar 15
Augusta 14
Totale 16.683
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Nome #
Haloperidol drug repurposing unveils ferroptosis involvement in breast cancer cells 303
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 301
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 298
Antioxidant properties and pharmacokinetic studies of new selective σ1 bifunctional ligands 212
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 204
Heme Oxygenase-1 and Carbon Monoxide Regulate Growth and Progression in Glioblastoma Cells 203
Design, synthesis, and pharmacological evaluation of NO donor-sigma receptors hybrids for the treatment of cancer 201
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 197
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 196
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 188
Heme Oxygenase Inhibition Sensitizes Neuroblastoma Cells to Carfilzomib 184
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 184
(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties 183
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 182
Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application 174
Non-competitive heme oxygenase-1 activity inhibitor reduces non-small cell lung cancer glutathione content and regulates cell proliferation 173
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 171
(+)-cis-N-ethyleneamino-N-normetazocine derivatives. Novel and selective sigma ligands with antagonist properties 169
A focus on Heme Oxygenase-1 (HO-1) inhibitors 168
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 166
Heme Oxygenase-1 Overexpression Promotes Uveal Melanoma Progression and Is Associated with Poor Clinical Outcomes 164
Effects of Novel Nitric Oxide-Releasing Molecules against Oxidative Stress on Retinal Pigmented Epithelial Cells 162
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 162
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 161
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 160
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 158
Development of Sigma Receptors Nitric Oxide Photodonor Ligands with Antiproliferative Activity 158
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 152
5-HT7 receptor ligands: recent developments and potential therapeutic applications 152
Combination of heme oxygenase-1 inhibitors and temozolomide to improve the anticancer effect in glioblastoma 151
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 151
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 149
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 147
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 147
Novel Acetamide-Based HO-1 Inhibitor Counteracts Glioblastoma Progression by Interfering with the Hypoxic–Angiogenic Pathway 146
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 145
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 144
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 141
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells 141
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 140
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 139
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 139
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 139
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 139
Berberine-styrene-co-maleic acid nanomicelles: unlocking opportunities for the treatment and prevention of bacterial infections 138
3-Amino-pyrrolo[3,4-c]pyrazole: Design and validation of a novel, highly versatile scaffold for kinase inhibition 137
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 136
New arylethanolimidazole derivatives as HO-1 inhibitors with cytotoxicity against MCF-7 breast cancer cells 136
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 134
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 132
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 131
Novel Sigma-1 receptor antagonists: From opioids to small molecules: What is new? 131
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 129
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 129
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 129
Ginseng and heme oxygenase-1: The link between an old herb and a new protective system 128
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 127
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 127
Heme oxygenase 1 inhibitor discovery and formulation into nanostructured lipid carriers as potent and selective treatment against triple negative metastatic breast cancer 126
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 126
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 126
Synthetic cannabinoids nano-micelles for the management of triple negative breast cancer 125
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 123
3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: A new class of CDK2 inhibitors 123
HO-1 INHIBITION POTENTIATES METFORMIN ANTINEOPLASTIC EFFECTS IN HUMAN PROSTATE CANCER CELLS UNDER LOW GLUCOSE CONCENTRATION 123
3-Amino-pyrrolo[3,4-c]pyrazoles: A new class of CDK2 inhibitors 123
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 123
Novel Sigma Receptors Ligands-Nitric Oxide Photodonor: Molecular Hybrids for Double-Targeted Antiproliferative Effect 122
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 122
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 121
The Effect of Silver Nanoparticles on Learning, Memory and Social Interaction in BALB/C Mice 121
The analgesic potential of glycosides derived from medicinal plants 121
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 120
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 120
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 120
Targeting the hydrophobic heme oxygenase-1 western region for the identification of novel and selective azole-based inhibitors. 119
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 119
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 118
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 118
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 118
Novel indole derivatives targeting HuR-mRNA complex to counteract high glucose damage in retinal endothelial cells 118
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 117
Analoghi non-peptidici della dinorfina A(1-8): progettazione, sintesi e valutazione farmacologica di agonisti ad elevata selettività Kappa. 116
Curcumin-laden hydrogel coating medical device for periprosthetic joint infection prevention and control 115
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 115
Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands 115
Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats 115
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 114
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 113
Curcumin I-SMA nanomicelles as promising therapeutic tool to tackle bacterial infections 111
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 111
Synthesis and Binding Properties of New Endothelin Receptor Ligands 111
Progress in the development of more effective and safer analgesics for pain management 111
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 110
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 110
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 109
Imidazole Derivatives as Heme Oxygenase-1 Inhibitors 107
Novel Insights on Ferroptosis Modulation as Potential Strategy for Cancer Treatment: When Nature Kills 106
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 106
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 106
Totale 14.401
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Categoria #
all - tutte 87.676
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 87.676
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.326 0 0 62 14 257 51 257 65 140 29 62 389
2022/20233.017 270 169 77 331 264 534 9 479 687 40 124 33
2023/20241.251 75 207 54 58 102 279 18 60 4 44 202 148
2024/20255.192 45 754 327 321 985 506 355 261 452 467 359 360
2025/202610.465 617 400 2.080 508 1.615 2.006 1.229 239 594 591 355 231
2026/2027876 308 459 109 0 0 0 0 0 0 0 0 0
Totale 25.627