IRIS
PITTALA', Valeria
 Distribuzione geografica
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Continente #
NA - Nord America 10.601
EU - Europa 6.061
AS - Asia 5.312
SA - Sud America 976
AF - Africa 665
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 8
Totale 23.632
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Nazione #
US - Stati Uniti d'America 10.232
SG - Singapore 2.809
RU - Federazione Russa 1.803
IT - Italia 1.558
CN - Cina 1.353
BR - Brasile 836
IE - Irlanda 806
UA - Ucraina 519
VN - Vietnam 388
CI - Costa d'Avorio 350
DE - Germania 340
FR - Francia 327
CA - Canada 287
KR - Corea 180
FI - Finlandia 159
GB - Regno Unito 148
NG - Nigeria 116
IN - India 111
HK - Hong Kong 76
SN - Senegal 67
SE - Svezia 62
PL - Polonia 61
JP - Giappone 57
ES - Italia 54
BD - Bangladesh 52
NL - Olanda 52
MX - Messico 51
AR - Argentina 48
IQ - Iraq 48
UZ - Uzbekistan 38
AT - Austria 35
ZA - Sudafrica 34
TR - Turchia 32
ID - Indonesia 30
KE - Kenya 25
MA - Marocco 24
CZ - Repubblica Ceca 22
EC - Ecuador 21
VE - Venezuela 21
CO - Colombia 18
PK - Pakistan 18
CH - Svizzera 17
IR - Iran 16
BJ - Benin 14
GR - Grecia 14
LT - Lituania 14
NP - Nepal 11
SA - Arabia Saudita 11
AE - Emirati Arabi Uniti 10
EG - Egitto 10
JM - Giamaica 10
JO - Giordania 10
BG - Bulgaria 9
CL - Cile 9
ET - Etiopia 9
AL - Albania 8
AU - Australia 8
LB - Libano 8
PH - Filippine 8
TN - Tunisia 8
BE - Belgio 7
PY - Paraguay 7
BO - Bolivia 6
IL - Israele 6
OM - Oman 6
RO - Romania 6
BY - Bielorussia 5
EU - Europa 5
HU - Ungheria 5
LV - Lettonia 5
MY - Malesia 5
PE - Perù 5
RS - Serbia 5
AZ - Azerbaigian 4
HN - Honduras 4
LU - Lussemburgo 4
MD - Moldavia 4
PA - Panama 4
PT - Portogallo 4
SY - Repubblica araba siriana 4
DZ - Algeria 3
GT - Guatemala 3
KG - Kirghizistan 3
KW - Kuwait 3
UY - Uruguay 3
XK - ???statistics.table.value.countryCode.XK??? 3
CR - Costa Rica 2
DK - Danimarca 2
DM - Dominica 2
GA - Gabon 2
GY - Guiana 2
MN - Mongolia 2
MT - Malta 2
NI - Nicaragua 2
PS - Palestinian Territory 2
TG - Togo 2
TH - Thailandia 2
TT - Trinidad e Tobago 2
TW - Taiwan 2
BH - Bahrain 1
Totale 23.618
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Città #
Dallas 1.883
Singapore 1.650
Chandler 1.083
Santa Clara 904
Dublin 804
Moscow 771
San Jose 655
Ashburn 584
Jacksonville 529
Chicago 444
Catania 397
Abidjan 350
Boardman 344
Houston 255
Cambridge 223
Lawrence 223
Lauterbourg 221
Andover 219
Nanjing 215
Munich 209
Beijing 205
Toronto 185
Hefei 182
Seoul 179
Los Angeles 154
Civitanova Marche 139
Ho Chi Minh City 127
Des Moines 115
Helsinki 105
Council Bluffs 104
São Paulo 103
San Mateo 97
Wilmington 94
New York 87
Hanoi 79
Rome 70
Dakar 67
Nanchang 67
Hong Kong 65
Shenyang 60
Buffalo 56
Columbus 55
The Dalles 55
Tokyo 54
Lagos 50
Saint Petersburg 48
Naples 47
Hebei 46
Palermo 46
Abuja 44
Orem 44
Ottawa 44
Changsha 42
Bremen 40
Jiaxing 40
Warsaw 40
Tianjin 39
Florence 38
Milan 37
Atlanta 32
Brooklyn 32
Redmond 30
Belo Horizonte 29
Montreal 27
Rio de Janeiro 27
Dong Ket 25
Phoenix 25
Falls Church 24
Johannesburg 24
Stockholm 23
Port Harcourt 22
Seattle 22
Turku 22
Amsterdam 21
London 21
Mumbai 21
Pune 21
Tashkent 21
Washington 21
Baghdad 20
Jakarta 20
Mexico City 20
Lappeenranta 19
Messina 19
Da Nang 18
Denver 18
Manchester 18
Redondo Beach 18
Norwalk 17
Boydton 16
Brasília 15
Chennai 15
Curitiba 15
Dhaka 15
Frankfurt am Main 15
Poplar 15
Cotonou 14
Guangzhou 14
Haiphong 14
Paris 14
Totale 15.951
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Nome #
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 293
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 290
Haloperidol drug repurposing unveils ferroptosis involvement in breast cancer cells 284
Antioxidant properties and pharmacokinetic studies of new selective σ1 bifunctional ligands 204
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 199
Design, synthesis, and pharmacological evaluation of NO donor-sigma receptors hybrids for the treatment of cancer 196
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 190
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 186
Heme Oxygenase-1 and Carbon Monoxide Regulate Growth and Progression in Glioblastoma Cells 186
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 177
Heme Oxygenase Inhibition Sensitizes Neuroblastoma Cells to Carfilzomib 177
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 172
Non-competitive heme oxygenase-1 activity inhibitor reduces non-small cell lung cancer glutathione content and regulates cell proliferation 169
(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties 164
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 164
A focus on Heme Oxygenase-1 (HO-1) inhibitors 162
(+)-cis-N-ethyleneamino-N-normetazocine derivatives. Novel and selective sigma ligands with antagonist properties 162
Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application 162
Heme Oxygenase-1 Overexpression Promotes Uveal Melanoma Progression and Is Associated with Poor Clinical Outcomes 155
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 154
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 154
Effects of Novel Nitric Oxide-Releasing Molecules against Oxidative Stress on Retinal Pigmented Epithelial Cells 152
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 152
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 151
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 151
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 146
Development of Sigma Receptors Nitric Oxide Photodonor Ligands with Antiproliferative Activity 146
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 145
5-HT7 receptor ligands: recent developments and potential therapeutic applications 145
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 142
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 142
Combination of heme oxygenase-1 inhibitors and temozolomide to improve the anticancer effect in glioblastoma 141
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 141
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 141
Novel Acetamide-Based HO-1 Inhibitor Counteracts Glioblastoma Progression by Interfering with the Hypoxic–Angiogenic Pathway 138
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 138
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 137
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells 137
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 134
3-Amino-pyrrolo[3,4-c]pyrazole: Design and validation of a novel, highly versatile scaffold for kinase inhibition 133
Berberine-styrene-co-maleic acid nanomicelles: unlocking opportunities for the treatment and prevention of bacterial infections 132
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 132
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 130
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 130
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 129
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 129
New arylethanolimidazole derivatives as HO-1 inhibitors with cytotoxicity against MCF-7 breast cancer cells 128
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 126
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 124
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 124
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 124
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 123
HO-1 INHIBITION POTENTIATES METFORMIN ANTINEOPLASTIC EFFECTS IN HUMAN PROSTATE CANCER CELLS UNDER LOW GLUCOSE CONCENTRATION 123
Ginseng and heme oxygenase-1: The link between an old herb and a new protective system 122
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 121
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 121
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 120
Synthetic cannabinoids nano-micelles for the management of triple negative breast cancer 120
Novel Sigma-1 receptor antagonists: From opioids to small molecules: What is new? 119
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 118
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 118
The Effect of Silver Nanoparticles on Learning, Memory and Social Interaction in BALB/C Mice 118
The analgesic potential of glycosides derived from medicinal plants 118
Heme oxygenase 1 inhibitor discovery and formulation into nanostructured lipid carriers as potent and selective treatment against triple negative metastatic breast cancer 117
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 117
3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: A new class of CDK2 inhibitors 116
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 116
3-Amino-pyrrolo[3,4-c]pyrazoles: A new class of CDK2 inhibitors 116
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 116
Novel Sigma Receptors Ligands-Nitric Oxide Photodonor: Molecular Hybrids for Double-Targeted Antiproliferative Effect 115
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 114
Targeting the hydrophobic heme oxygenase-1 western region for the identification of novel and selective azole-based inhibitors. 114
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 114
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 113
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 113
Analoghi non-peptidici della dinorfina A(1-8): progettazione, sintesi e valutazione farmacologica di agonisti ad elevata selettività Kappa. 112
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 112
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 111
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 111
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 110
Novel indole derivatives targeting HuR-mRNA complex to counteract high glucose damage in retinal endothelial cells 110
Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats 109
Progress in the development of more effective and safer analgesics for pain management 109
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 108
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 108
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 108
Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands 108
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 105
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 105
Curcumin I-SMA nanomicelles as promising therapeutic tool to tackle bacterial infections 104
Imidazole Derivatives as Heme Oxygenase-1 Inhibitors 103
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 102
Synthesis and experimental validation of new designed heterocyclic compounds with antiproliferative activity versus breast cancer cell lines MCF-7 and MDA-MB-231 102
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 101
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 101
Growing the molecular architecture of imidazole-like ligands in HO-1 complexes 101
Nonpeptide Analogues of Dynorphin A(1-8): Design, Synthesis, and Pharmacological Evaluation of k-Selective Agonists 100
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 100
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 98
Targeting STATs in neuroinflammation: The road less traveled! 98
Totale 13.578
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Categoria #
all - tutte 75.858
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 75.858
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021194 0 0 0 0 0 0 0 0 0 23 126 45
2021/20221.756 199 231 62 14 257 51 257 65 140 29 62 389
2022/20233.017 270 169 77 331 264 534 9 479 687 40 124 33
2023/20241.251 75 207 54 58 102 279 18 60 4 44 202 148
2024/20255.192 45 754 327 321 985 506 355 261 452 467 359 360
2025/20269.865 617 400 2.080 508 1.615 2.006 1.229 239 594 577 0 0
Totale 24.151