IRIS
PITTALA', Valeria
 Distribuzione geografica
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Continente #
NA - Nord America 6.665
EU - Europa 3.774
AS - Asia 2.391
SA - Sud America 583
AF - Africa 341
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 5
Totale 13.765
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Nazione #
US - Stati Uniti d'America 6.409
IT - Italia 1.422
SG - Singapore 1.363
CN - Cina 812
IE - Irlanda 804
BR - Brasile 542
UA - Ucraina 512
DE - Germania 318
CI - Costa d'Avorio 247
CA - Canada 238
RU - Federazione Russa 217
FI - Finlandia 139
GB - Regno Unito 69
SN - Senegal 66
FR - Francia 57
IN - India 41
SE - Svezia 41
NL - Olanda 33
AT - Austria 30
VN - Vietnam 30
UZ - Uzbekistan 29
ES - Italia 27
PL - Polonia 26
CZ - Repubblica Ceca 17
CH - Svizzera 16
HK - Hong Kong 14
IQ - Iraq 13
AR - Argentina 12
MA - Marocco 12
TR - Turchia 12
IR - Iran 11
JP - Giappone 11
GR - Grecia 10
MX - Messico 10
VE - Venezuela 10
BD - Bangladesh 9
BG - Bulgaria 7
EC - Ecuador 7
BE - Belgio 6
NP - Nepal 6
PK - Pakistan 6
AU - Australia 5
EU - Europa 5
RO - Romania 5
ZA - Sudafrica 5
CO - Colombia 4
IL - Israele 4
LB - Libano 4
LU - Lussemburgo 4
AE - Emirati Arabi Uniti 3
CL - Cile 3
EG - Egitto 3
HU - Ungheria 3
JM - Giamaica 3
KE - Kenya 3
OM - Oman 3
PT - Portogallo 3
SA - Arabia Saudita 3
TN - Tunisia 3
AZ - Azerbaigian 2
GT - Guatemala 2
HN - Honduras 2
JO - Giordania 2
MD - Moldavia 2
MN - Mongolia 2
NG - Nigeria 2
PE - Perù 2
PH - Filippine 2
PS - Palestinian Territory 2
PY - Paraguay 2
AL - Albania 1
BY - Bielorussia 1
CY - Cipro 1
GY - Guiana 1
ID - Indonesia 1
KG - Kirghizistan 1
KR - Corea 1
KW - Kuwait 1
LT - Lituania 1
LV - Lettonia 1
MT - Malta 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PA - Panama 1
SY - Repubblica araba siriana 1
TW - Taiwan 1
Totale 13.765
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Città #
Chandler 1.087
Santa Clara 869
Dublin 803
Singapore 787
Jacksonville 531
Chicago 431
Catania 365
Boardman 346
Houston 267
Abidjan 247
Cambridge 224
Lawrence 223
Andover 220
Ashburn 220
Nanjing 214
Munich 209
Toronto 174
Civitanova Marche 140
Des Moines 115
San Mateo 98
Wilmington 95
Helsinki 93
Nanchang 67
Dakar 66
Council Bluffs 63
Shenyang 60
The Dalles 56
Saint Petersburg 49
São Paulo 49
Hebei 46
Naples 46
Rome 45
Hefei 44
Beijing 43
Ottawa 43
Changsha 41
Jiaxing 41
Bremen 40
Tianjin 39
Florence 35
Los Angeles 33
Palermo 32
Redmond 30
Dong Ket 25
Falls Church 24
Milan 24
Belo Horizonte 23
Moscow 22
Turku 22
Pune 21
New York 19
Washington 19
Messina 18
Norwalk 17
Rio de Janeiro 17
Boydton 16
Seattle 16
Civitavecchia 13
Tashkent 13
Augusta 12
Barcelona 12
Guangzhou 12
Osio Sotto 12
Phoenix 12
Salerno 12
Aci Catena 11
Ann Arbor 11
Lappeenranta 11
Zhengzhou 11
Den Haag 10
Kunming 10
London 10
Padova 10
Redwood City 10
Shanghai 10
Tokyo 10
Viagrande 10
Curitiba 9
Garbagnate Milanese 9
Grafing 9
Guarulhos 9
Hangzhou 9
Hong Kong 9
Jyväskylä 9
Ningbo 9
Turin 9
Ardabil 8
Brno 8
Brooklyn 8
Campinas 8
Dallas 8
Madrid 8
Paris 8
Pozzallo 8
Tremestieri Etneo 8
Vienna 8
Warsaw 8
Acireale 7
Amsterdam 7
Brasília 7
Totale 9.421
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Nome #
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 215
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 208
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 133
Antioxidant properties and pharmacokinetic studies of new selective σ1 bifunctional ligands 131
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 130
Design, synthesis, and pharmacological evaluation of NO donor-sigma receptors hybrids for the treatment of cancer 127
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 122
Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application 114
Heme Oxygenase Inhibition Sensitizes Neuroblastoma Cells to Carfilzomib 113
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 108
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 106
Heme Oxygenase-1 and Carbon Monoxide Regulate Growth and Progression in Glioblastoma Cells 105
Synthetic cannabinoids nano-micelles for the management of triple negative breast cancer 103
Effects of Novel Nitric Oxide-Releasing Molecules against Oxidative Stress on Retinal Pigmented Epithelial Cells 100
A focus on Heme Oxygenase-1 (HO-1) inhibitors 98
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 94
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 93
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 93
The Effect of Silver Nanoparticles on Learning, Memory and Social Interaction in BALB/C Mice 92
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 90
Non-competitive heme oxygenase-1 activity inhibitor reduces non-small cell lung cancer glutathione content and regulates cell proliferation 90
Development of Sigma Receptors Nitric Oxide Photodonor Ligands with Antiproliferative Activity 88
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 87
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 86
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 86
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 85
(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties 85
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 84
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 84
New arylethanolimidazole derivatives as HO-1 inhibitors with cytotoxicity against MCF-7 breast cancer cells 84
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 83
Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands 83
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 81
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 80
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 78
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 78
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 78
Heme Oxygenase-1 Overexpression Promotes Uveal Melanoma Progression and Is Associated with Poor Clinical Outcomes 77
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 77
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 77
Novel Sigma-1 receptor antagonists: From opioids to small molecules: What is new? 76
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 75
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 75
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 75
(+)-cis-N-ethyleneamino-N-normetazocine derivatives. Novel and selective sigma ligands with antagonist properties 74
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 73
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 73
5-HT7 receptor ligands: recent developments and potential therapeutic applications 73
Targeting STATs in neuroinflammation: The road less traveled! 73
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 73
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 72
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 72
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 72
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 72
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 71
Nonpeptide Analogues of Dynorphin A(1-8): Design, Synthesis, and Pharmacological Evaluation of k-Selective Agonists 71
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 71
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 71
3-Amino-pyrrolo[3,4-c]pyrazole: Design and validation of a novel, highly versatile scaffold for kinase inhibition 70
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 70
Progress in the development of more effective and safer analgesics for pain management 70
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 70
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 69
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 69
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 68
Role of the Nrf2/HO-1 axis in bronchopulmonary dysplasia and hyperoxic lung injuries 68
Synthesis and experimental validation of new designed heterocyclic compounds with antiproliferative activity versus breast cancer cell lines MCF-7 and MDA-MB-231 68
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 67
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 67
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 67
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 67
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 66
Ginseng and heme oxygenase-1: The link between an old herb and a new protective system 66
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 66
Novel Sigma Receptors Ligands-Nitric Oxide Photodonor: Molecular Hybrids for Double-Targeted Antiproliferative Effect 65
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 65
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 64
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 64
Targeting the hydrophobic heme oxygenase-1 western region for the identification of novel and selective azole-based inhibitors. 64
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 64
Novel indole derivatives targeting HuR-mRNA complex to counteract high glucose damage in retinal endothelial cells 64
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells 63
Synthesis and Pharmacological Evaluation of Peptidomimetic of the Kappa-Opioid Receptors 63
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 63
HO-1 INHIBITION POTENTIATES METFORMIN ANTINEOPLASTIC EFFECTS IN HUMAN PROSTATE CANCER CELLS UNDER LOW GLUCOSE CONCENTRATION 63
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 62
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 62
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 62
Sintesi di 1,2,4 Triazoli come Ligandi per i Recettori delle Endoteline 61
Analoghi non-peptidici della dinorfina A(1-8): progettazione, sintesi e valutazione farmacologica di agonisti ad elevata selettività Kappa. 61
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 61
Design and synthesis of novel potential ligands for endothelin receptors 61
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 61
Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats 61
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 60
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 60
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 60
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 60
The analgesic potential of glycosides derived from medicinal plants 60
Growing the molecular architecture of imidazole-like ligands in HO-1 complexes 60
Totale 8.040
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Categoria #
all - tutte 52.952
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 52.952
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202062 0 0 0 0 0 0 0 0 0 0 0 62
2020/20211.041 12 101 126 45 333 24 117 10 79 23 126 45
2021/20221.764 200 232 62 14 258 51 258 66 141 29 62 391
2022/20233.030 271 169 77 333 267 535 9 482 689 40 125 33
2023/20241.254 75 209 55 58 102 279 18 60 4 44 202 148
2024/20255.127 45 757 329 322 989 509 355 262 453 469 362 275
Totale 14.282