IRIS
PITTALA', Valeria
 Distribuzione geografica
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Continente #
NA - Nord America 6.922
EU - Europa 3.840
AS - Asia 2.841
SA - Sud America 634
AF - Africa 350
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 5
Totale 14.599
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Nazione #
US - Stati Uniti d'America 6.652
SG - Singapore 1.502
IT - Italia 1.441
CN - Cina 995
IE - Irlanda 805
BR - Brasile 588
UA - Ucraina 513
DE - Germania 320
CI - Costa d'Avorio 247
CA - Canada 245
RU - Federazione Russa 217
FI - Finlandia 139
GB - Regno Unito 87
SN - Senegal 66
FR - Francia 61
IN - India 58
KR - Corea 58
SE - Svezia 42
VN - Vietnam 40
PL - Polonia 34
NL - Olanda 33
AT - Austria 32
ES - Italia 32
UZ - Uzbekistan 29
BD - Bangladesh 23
IQ - Iraq 22
JP - Giappone 19
CZ - Repubblica Ceca 17
CH - Svizzera 16
TR - Turchia 15
AR - Argentina 14
HK - Hong Kong 14
MA - Marocco 14
MX - Messico 14
VE - Venezuela 12
IR - Iran 11
GR - Grecia 10
BG - Bulgaria 8
ZA - Sudafrica 8
EC - Ecuador 7
PK - Pakistan 7
AU - Australia 6
BE - Belgio 6
JO - Giordania 6
LB - Libano 6
NP - Nepal 6
EU - Europa 5
IL - Israele 5
KE - Kenya 5
RO - Romania 5
AE - Emirati Arabi Uniti 4
CO - Colombia 4
JM - Giamaica 4
LT - Lituania 4
LU - Lussemburgo 4
SA - Arabia Saudita 4
TN - Tunisia 4
CL - Cile 3
EG - Egitto 3
HU - Ungheria 3
NG - Nigeria 3
OM - Oman 3
PT - Portogallo 3
AL - Albania 2
AZ - Azerbaigian 2
GT - Guatemala 2
GY - Guiana 2
HN - Honduras 2
MD - Moldavia 2
MN - Mongolia 2
PE - Perù 2
PH - Filippine 2
PS - Palestinian Territory 2
PY - Paraguay 2
BY - Bielorussia 1
CY - Cipro 1
DO - Repubblica Dominicana 1
ID - Indonesia 1
KG - Kirghizistan 1
KW - Kuwait 1
LV - Lettonia 1
MT - Malta 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PA - Panama 1
SY - Repubblica araba siriana 1
TT - Trinidad e Tobago 1
TW - Taiwan 1
Totale 14.599
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Città #
Chandler 1.087
Singapore 899
Santa Clara 876
Dublin 803
Jacksonville 531
Chicago 439
Catania 377
Boardman 346
Houston 267
Ashburn 249
Abidjan 247
Cambridge 224
Lawrence 223
Andover 220
Nanjing 214
Munich 209
Toronto 175
Beijing 140
Civitanova Marche 140
Hefei 129
Des Moines 115
San Mateo 98
Wilmington 95
Helsinki 93
Nanchang 67
Council Bluffs 66
Dakar 66
Shenyang 60
Seoul 57
Columbus 56
São Paulo 56
The Dalles 56
Saint Petersburg 49
Rome 48
Los Angeles 47
Hebei 46
Naples 46
Ottawa 43
Changsha 41
Jiaxing 41
Bremen 40
Tianjin 39
Florence 35
Palermo 32
Redmond 30
Milan 26
New York 26
Dong Ket 25
Belo Horizonte 24
Falls Church 24
Brooklyn 22
Moscow 22
Turku 22
Pune 21
Washington 21
Messina 19
Rio de Janeiro 19
Seattle 18
Tokyo 18
Norwalk 17
Boydton 16
Warsaw 16
Augusta 13
Civitavecchia 13
Guangzhou 13
Phoenix 13
Tashkent 13
Barcelona 12
Dallas 12
London 12
Mumbai 12
Osio Sotto 12
Salerno 12
San Francisco 12
Aci Catena 11
Ann Arbor 11
Lappeenranta 11
Zhengzhou 11
Curitiba 10
Den Haag 10
Kunming 10
Padova 10
Redwood City 10
Shanghai 10
Viagrande 10
Baghdad 9
Campinas 9
Garbagnate Milanese 9
Grafing 9
Guarulhos 9
Hangzhou 9
Hong Kong 9
Jyväskylä 9
Ningbo 9
Turin 9
Vienna 9
Ardabil 8
Atlanta 8
Brasília 8
Brno 8
Totale 9.967
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Nome #
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 221
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 213
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 137
Antioxidant properties and pharmacokinetic studies of new selective σ1 bifunctional ligands 134
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 133
Design, synthesis, and pharmacological evaluation of NO donor-sigma receptors hybrids for the treatment of cancer 130
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 126
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 119
Heme Oxygenase Inhibition Sensitizes Neuroblastoma Cells to Carfilzomib 118
Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application 116
Heme Oxygenase-1 and Carbon Monoxide Regulate Growth and Progression in Glioblastoma Cells 110
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 109
Effects of Novel Nitric Oxide-Releasing Molecules against Oxidative Stress on Retinal Pigmented Epithelial Cells 104
Synthetic cannabinoids nano-micelles for the management of triple negative breast cancer 104
A focus on Heme Oxygenase-1 (HO-1) inhibitors 102
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 102
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 97
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 95
The Effect of Silver Nanoparticles on Learning, Memory and Social Interaction in BALB/C Mice 94
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 93
Development of Sigma Receptors Nitric Oxide Photodonor Ligands with Antiproliferative Activity 93
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 92
Non-competitive heme oxygenase-1 activity inhibitor reduces non-small cell lung cancer glutathione content and regulates cell proliferation 92
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 89
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 89
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 89
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 88
Heme Oxygenase-1 Overexpression Promotes Uveal Melanoma Progression and Is Associated with Poor Clinical Outcomes 88
(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties 88
New arylethanolimidazole derivatives as HO-1 inhibitors with cytotoxicity against MCF-7 breast cancer cells 88
Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands 87
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 87
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 87
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 85
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 85
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 83
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 83
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 81
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 81
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 80
(+)-cis-N-ethyleneamino-N-normetazocine derivatives. Novel and selective sigma ligands with antagonist properties 80
Novel Sigma-1 receptor antagonists: From opioids to small molecules: What is new? 80
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 80
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 79
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 78
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 78
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 77
5-HT7 receptor ligands: recent developments and potential therapeutic applications 77
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 77
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 77
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 77
3-Amino-pyrrolo[3,4-c]pyrazole: Design and validation of a novel, highly versatile scaffold for kinase inhibition 76
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 76
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 76
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells 75
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 75
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 74
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 74
Targeting STATs in neuroinflammation: The road less traveled! 74
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 73
Nonpeptide Analogues of Dynorphin A(1-8): Design, Synthesis, and Pharmacological Evaluation of k-Selective Agonists 73
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 73
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 72
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 72
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 72
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 72
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies 71
Novel Sigma Receptors Ligands-Nitric Oxide Photodonor: Molecular Hybrids for Double-Targeted Antiproliferative Effect 71
Progress in the development of more effective and safer analgesics for pain management 71
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 70
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 70
Synthesis and experimental validation of new designed heterocyclic compounds with antiproliferative activity versus breast cancer cell lines MCF-7 and MDA-MB-231 70
Targeting the hydrophobic heme oxygenase-1 western region for the identification of novel and selective azole-based inhibitors. 70
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 70
Ginseng and heme oxygenase-1: The link between an old herb and a new protective system 70
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 69
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 69
Role of the Nrf2/HO-1 axis in bronchopulmonary dysplasia and hyperoxic lung injuries 69
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 68
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 68
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 68
HO-1 INHIBITION POTENTIATES METFORMIN ANTINEOPLASTIC EFFECTS IN HUMAN PROSTATE CANCER CELLS UNDER LOW GLUCOSE CONCENTRATION 68
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D-QSAR Coupled to Scaffold-Hopping Analysis 68
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 66
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 66
Novel indole derivatives targeting HuR-mRNA complex to counteract high glucose damage in retinal endothelial cells 66
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 65
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-​1 65
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors 65
Synthesis of new 5-phenyl[1,2,4]triazole derivatives as ligands for the 5-HT1A serotonin receptor 64
Synthesis and Endothelin Receptors Binding Affinity of New 1,3,5- Substituted Pyrrole-2-Carboxylic Acid Derivatives 64
Sintesi di 1,2,4 Triazoli come Ligandi per i Recettori delle Endoteline 64
Synthesis and Binding Properties of New Endothelin Receptor Ligands 64
Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats 64
Novel Acetamide-Based HO-1 Inhibitor Counteracts Glioblastoma Progression by Interfering with the Hypoxic–Angiogenic Pathway 63
Synthesis and Pharmacological Evaluation of Peptidomimetic of the Kappa-Opioid Receptors 63
Analoghi non-peptidici della dinorfina A(1-8): progettazione, sintesi e valutazione farmacologica di agonisti ad elevata selettività Kappa. 63
Nuovi Arilpiperazinilalchilpirrolopirimidindioni come ligandi potenti e selettivi per i recettori α1-adrenergici 63
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 63
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 63
Totale 8.430
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Categoria #
all - tutte 56.865
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 56.865
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.029 0 101 126 45 333 24 117 10 79 23 126 45
2021/20221.764 200 232 62 14 258 51 258 66 141 29 62 391
2022/20233.030 271 169 77 333 267 535 9 482 689 40 125 33
2023/20241.254 75 209 55 58 102 279 18 60 4 44 202 148
2024/20255.213 45 757 329 322 989 509 355 262 453 469 362 361
2025/2026748 618 130 0 0 0 0 0 0 0 0 0 0
Totale 15.116