IRIS
PITTALA', Valeria
 Distribuzione geografica
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Continente #
NA - Nord America 9.438
EU - Europa 5.579
AS - Asia 4.443
SA - Sud America 844
AF - Africa 487
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 6
Totale 20.804
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Nazione #
US - Stati Uniti d'America 9.133
SG - Singapore 2.527
RU - Federazione Russa 1.806
IT - Italia 1.489
CN - Cina 1.258
IE - Irlanda 808
BR - Brasile 753
UA - Ucraina 513
CI - Costa d'Avorio 349
DE - Germania 324
CA - Canada 261
VN - Vietnam 165
FI - Finlandia 142
GB - Regno Unito 113
KR - Corea 92
IN - India 72
FR - Francia 66
SN - Senegal 66
SE - Svezia 54
HK - Hong Kong 51
JP - Giappone 51
PL - Polonia 48
ES - Italia 45
NL - Olanda 39
AR - Argentina 36
AT - Austria 33
BD - Bangladesh 31
MX - Messico 31
IQ - Iraq 30
UZ - Uzbekistan 30
ID - Indonesia 26
TR - Turchia 21
EC - Ecuador 19
MA - Marocco 18
CZ - Repubblica Ceca 17
CH - Svizzera 16
IR - Iran 16
ZA - Sudafrica 16
VE - Venezuela 15
BJ - Benin 14
LT - Lituania 11
GR - Grecia 10
PK - Pakistan 10
BG - Bulgaria 9
AE - Emirati Arabi Uniti 7
CO - Colombia 7
EG - Egitto 7
NP - Nepal 7
SA - Arabia Saudita 7
AU - Australia 6
BE - Belgio 6
IL - Israele 6
JO - Giordania 6
KE - Kenya 6
LB - Libano 6
EU - Europa 5
RO - Romania 5
TN - Tunisia 5
AL - Albania 4
CL - Cile 4
JM - Giamaica 4
LU - Lussemburgo 4
OM - Oman 4
PY - Paraguay 4
AZ - Azerbaigian 3
BY - Bielorussia 3
HU - Ungheria 3
MD - Moldavia 3
NG - Nigeria 3
PE - Perù 3
PH - Filippine 3
PT - Portogallo 3
ET - Etiopia 2
GT - Guatemala 2
GY - Guiana 2
HN - Honduras 2
KW - Kuwait 2
LV - Lettonia 2
MN - Mongolia 2
MY - Malesia 2
PA - Panama 2
PS - Palestinian Territory 2
TT - Trinidad e Tobago 2
BH - Bahrain 1
CY - Cipro 1
DO - Repubblica Dominicana 1
GE - Georgia 1
GN - Guinea 1
KG - Kirghizistan 1
MT - Malta 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
RS - Serbia 1
SY - Repubblica araba siriana 1
TW - Taiwan 1
UY - Uruguay 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 20.804
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Città #
Dallas 1.881
Singapore 1.426
Chandler 1.087
Santa Clara 889
Dublin 806
Moscow 772
Jacksonville 531
Chicago 441
Ashburn 423
Catania 393
Abidjan 349
Boardman 346
Houston 271
Cambridge 224
Lawrence 223
Andover 220
Nanjing 214
Munich 209
Beijing 203
Hefei 182
Toronto 180
Civitanova Marche 140
Los Angeles 138
Des Moines 115
San Mateo 98
Wilmington 95
Helsinki 93
Seoul 91
São Paulo 82
Nanchang 67
Council Bluffs 66
Dakar 66
Ho Chi Minh City 63
Shenyang 60
New York 59
Columbus 56
The Dalles 56
Tokyo 50
Buffalo 49
Rome 49
Saint Petersburg 49
Naples 47
Hebei 46
Hong Kong 46
Ottawa 43
Changsha 42
Jiaxing 41
Bremen 40
Tianjin 40
San Jose 39
Florence 36
Palermo 34
Milan 30
Redmond 30
Brooklyn 29
Warsaw 29
Hanoi 27
Dong Ket 25
Belo Horizonte 24
Falls Church 24
Rio de Janeiro 24
Turku 22
Pune 21
Washington 21
Atlanta 20
Messina 20
Phoenix 20
Seattle 20
Jakarta 18
Orem 18
Redondo Beach 18
Norwalk 17
Boydton 16
London 16
Mumbai 16
Stockholm 16
Brasília 15
Curitiba 15
Montreal 15
Baghdad 14
Cotonou 14
Guangzhou 14
Lappeenranta 14
Tashkent 14
Augusta 13
Civitavecchia 13
Manchester 13
Barcelona 12
Osio Sotto 12
Poplar 12
Porto Alegre 12
Salerno 12
San Francisco 12
Aci Catena 11
Amsterdam 11
Ann Arbor 11
Denver 11
Johannesburg 11
Paris 11
Tremestieri Etneo 11
Totale 14.090
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Nome #
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors 278
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alpha1-adrenoceptor ligands 273
Haloperidol drug repurposing unveils ferroptosis involvement in breast cancer cells 245
Antioxidant properties and pharmacokinetic studies of new selective σ1 bifunctional ligands 188
Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death 179
Design, synthesis, and pharmacological evaluation of NO donor-sigma receptors hybrids for the treatment of cancer 176
Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent in Vitro Antiproliferative Activity 170
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT7 receptor 166
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells 159
Heme Oxygenase Inhibition Sensitizes Neuroblastoma Cells to Carfilzomib 158
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMAN MICROVASCULAR RETINAL ENDOTHELIAL CELLS 156
Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application 150
Heme Oxygenase-1 and Carbon Monoxide Regulate Growth and Progression in Glioblastoma Cells 150
Non-competitive heme oxygenase-1 activity inhibitor reduces non-small cell lung cancer glutathione content and regulates cell proliferation 149
(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties 147
(E)-?-[[(5-Substituted)1H-indol-3-yl]methylene]benzeneacetic Acid and Amide Derivatives: Synthesis, Characterization, and Evaluation of in vitro Antiproliferative Activity 147
A focus on Heme Oxygenase-1 (HO-1) inhibitors 142
(E)-alfa-[[(5-substituted)1H-indol-3-yl]methylene]benzeneacetic acid and amide derivatives: synthesis, characterization, and evaluation of in vitro antiproliferative activity 140
Heme Oxygenase-1 Overexpression Promotes Uveal Melanoma Progression and Is Associated with Poor Clinical Outcomes 138
Effects of Novel Nitric Oxide-Releasing Molecules against Oxidative Stress on Retinal Pigmented Epithelial Cells 137
(+)-cis-N-ethyleneamino-N-normetazocine derivatives. Novel and selective sigma ligands with antagonist properties 137
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors 136
A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis 134
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dioni: una nuova classe di ligandi potenti e selettivi per il recettori alfa1-adrenergici 133
Glucose-impaired Corneal Re-epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate 132
Development of Sigma Receptors Nitric Oxide Photodonor Ligands with Antiproliferative Activity 129
3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high affinity and selective alpha1-adrenoceptor ligands 129
A New benzoxazolone and benzothiazolone derivatives as potential 5-HT7 receptor ligands 128
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 128
5-HT7 receptor ligands: recent developments and potential therapeutic applications 126
Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides 125
3-Amino-pyrrolo[3,4-c]pyrazole: Design and validation of a novel, highly versatile scaffold for kinase inhibition 125
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts 124
Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells 123
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells 121
Combination of heme oxygenase-1 inhibitors and temozolomide to improve the anticancer effect in glioblastoma 121
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione Derivatives: Novel, Potent and Selective alfa1-Adrenoceptor Ligands 121
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands 120
ATTIVITÀ ANTIOSSIDANTE IN VITRO DI DERIVATI DELL’IDEBENONE 119
Caratterizzazione chimico-fisica ed attività antiossidante in vitro del triestere trans-resveratrolotrolox. 118
Synthetic cannabinoids nano-micelles for the management of triple negative breast cancer 118
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors 117
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation 116
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 116
Novel Acetamide-Based HO-1 Inhibitor Counteracts Glioblastoma Progression by Interfering with the Hypoxic–Angiogenic Pathway 115
New arylethanolimidazole derivatives as HO-1 inhibitors with cytotoxicity against MCF-7 breast cancer cells 115
Development of New Benzylpiperazine Derivatives as σ1Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects 114
Berberine-styrene-co-maleic acid nanomicelles: unlocking opportunities for the treatment and prevention of bacterial infections 112
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the alpha(1)-adrenergic receptor subtypes 112
A Facile Synthesis of New 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxyamido-3-carboxythieno[2,3-c]pyridine Derivatives as Potential Endothelin Receptors Ligands 112
Fourfold filtered statistical/computational approach for the identification of imidazole compounds as HO-1 inhibitors from natural products 112
3-Arylpiperazinylalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: novel, potent and selective alpha1-adrenoceptor ligands 111
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole, derivatives as potent and selective 5-HT1A serotonin receptor ligands 111
Novel structural insight into inhibitors of heme oxygenase-1 (ho-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation 110
The Effect of Silver Nanoparticles on Learning, Memory and Social Interaction in BALB/C Mice 109
3-Arylpiperazynilalkyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives: as novel, potent and selective alfa1-adrenoceptor ligands 108
Design and synthesis of new homo and hetero bis-piperazinyl-1- propanone derivatives as 5-HT7R selective ligands over 5-HT1AR 108
Novel Sigma-1 receptor antagonists: From opioids to small molecules: What is new? 108
3-Amino-pyrrolo[3,4-c]pyrazoles: A new class of CDK2 inhibitors 107
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines 106
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis 106
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective 106
Ginseng and heme oxygenase-1: The link between an old herb and a new protective system 105
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands 104
HO-1 INHIBITION POTENTIATES METFORMIN ANTINEOPLASTIC EFFECTS IN HUMAN PROSTATE CANCER CELLS UNDER LOW GLUCOSE CONCENTRATION 104
The analgesic potential of glycosides derived from medicinal plants 104
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una Nuova Classe di Ligandi Potenti ed Altamente Selettivi per i Recettori alfa1 Adrenergici 103
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia 103
Novel Caffeic Acid Phenethyl Ester (CAPE) Analogues as Inducers of Heme Oxygenase-1 101
Novel Sigma Receptors Ligands-Nitric Oxide Photodonor: Molecular Hybrids for Double-Targeted Antiproliferative Effect 101
Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands 101
Analoghi non-peptidici della dinorfina A(1-8): progettazione, sintesi e valutazione farmacologica di agonisti ad elevata selettività Kappa. 100
Haloperidol Metabolite II Valproate Ester: Antiangiogenic Activity in Human Microvascular Retinal Endothelial Cells 100
Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs 99
Novel indole derivatives targeting HuR-mRNA complex to counteract high glucose damage in retinal endothelial cells 99
Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region 99
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects 98
S2RSLDB: A comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands 98
Targeting the hydrophobic heme oxygenase-1 western region for the identification of novel and selective azole-based inhibitors. 97
Synthesis and in vitro antioxidant activity of a novel idebenone ester with pyroglutamic acid. 97
Heme oxygenase 1 inhibitor discovery and formulation into nanostructured lipid carriers as potent and selective treatment against triple negative metastatic breast cancer 96
Acidi (E)-alfa-[(1H-indol-3-il)metilene]benzeneacetici: una nuova classe di ligandi per i recettori delle endoteline 96
Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions 95
3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: A new class of CDK2 inhibitors 95
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents 95
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands 95
Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update 94
Serotonin 5-HT3 and 5-HT4 Ligands: An Update of Medicinal Chemistry Research in the Last Few Years 93
Nonpeptide Analogues of Dynorphin A(1-8): Design, Synthesis, and Pharmacological Evaluation of k-Selective Agonists 92
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties 91
Synthesis and experimental validation of new designed heterocyclic compounds with antiproliferative activity versus breast cancer cell lines MCF-7 and MDA-MB-231 91
Progress in the development of more effective and safer analgesics for pain management 91
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor 90
Targeting STATs in neuroinflammation: The road less traveled! 90
Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats 90
Curcumin I-SMA nanomicelles as promising therapeutic tool to tackle bacterial infections 89
Heme Oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia 89
SYNTHESIS OF 1,2,4-TRIAZOLE DERIVATIVES: BINDING PROPERTIES ON ENDOTHELIN RECEPTORS 88
Evaluation of Novel Imidazole- and 1,2,4 Triazole-based Compounds as Heme Oxygenase-1 (HO-1) Inhibitors. 88
Novel Insights on Ferroptosis Modulation as Potential Strategy for Cancer Treatment: When Nature Kills 87
Totale 12.074
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Categoria #
all - tutte 70.583
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 70.583
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021424 0 0 0 0 0 24 117 10 79 23 126 45
2021/20221.764 200 232 62 14 258 51 258 66 141 29 62 391
2022/20233.030 271 169 77 333 267 535 9 482 689 40 125 33
2023/20241.254 75 209 55 58 102 279 18 60 4 44 202 148
2024/20255.213 45 757 329 322 989 509 355 262 453 469 362 361
2025/20266.954 618 400 2.089 508 1.620 1.719 0 0 0 0 0 0
Totale 21.322