IRIS
PARENTI, Carmela
 Distribuzione geografica
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Continente #
NA - Nord America 4.493
EU - Europa 2.462
AS - Asia 729
AF - Africa 403
OC - Oceania 11
SA - Sud America 9
Continente sconosciuto - Info sul continente non disponibili 6
Totale 8.113
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Nazione #
US - Stati Uniti d'America 4.289
IE - Irlanda 634
IT - Italia 633
CN - Cina 598
UA - Ucraina 537
CI - Costa d'Avorio 290
CA - Canada 204
RU - Federazione Russa 179
DE - Germania 149
SN - Senegal 103
SE - Svezia 96
GB - Regno Unito 46
FR - Francia 43
IN - India 40
BE - Belgio 27
VN - Vietnam 22
ES - Italia 18
CH - Svizzera 17
SG - Singapore 17
NL - Olanda 16
AT - Austria 14
JP - Giappone 11
PL - Polonia 11
UZ - Uzbekistan 11
AU - Australia 10
GR - Grecia 10
HU - Ungheria 7
IR - Iran 7
EU - Europa 6
LB - Libano 6
CZ - Repubblica Ceca 4
FI - Finlandia 4
HK - Hong Kong 4
IL - Israele 4
NG - Nigeria 4
NO - Norvegia 4
PK - Pakistan 4
BR - Brasile 3
DZ - Algeria 3
PE - Perù 3
AL - Albania 2
BG - Bulgaria 2
CL - Cile 2
DK - Danimarca 2
EG - Egitto 2
ID - Indonesia 2
AE - Emirati Arabi Uniti 1
CO - Colombia 1
EE - Estonia 1
HR - Croazia 1
LI - Liechtenstein 1
NZ - Nuova Zelanda 1
PT - Portogallo 1
RO - Romania 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
SL - Sierra Leone 1
TH - Thailandia 1
TR - Turchia 1
Totale 8.113
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Città #
Houston 1.018
Chandler 815
Dublin 630
Jacksonville 521
Abidjan 290
Ashburn 219
Catania 208
Nanjing 194
Lawrence 178
Cambridge 177
Andover 176
Toronto 158
Dakar 103
Boardman 99
Wilmington 96
San Mateo 89
Bremen 85
Des Moines 73
Nanchang 64
Shenyang 52
Saint Petersburg 49
Jiaxing 44
Ottawa 42
Tianjin 40
Changsha 37
Grafing 35
Hebei 35
Rome 33
Brussels 26
Beijing 24
Dong Ket 17
Falls Church 17
Moscow 17
Pune 17
Jinan 15
Ningbo 15
Norwalk 15
Seattle 14
Augusta 13
Washington 13
Messina 12
Zhengzhou 11
Leawood 9
Los Angeles 9
Madrid 9
Mascalucia 9
New York 9
Tappahannock 9
Ann Arbor 8
Fremont 8
Kunming 8
Liberty Lake 8
San Giovanni la Punta 8
Budapest 7
East Stroudsburg 7
Siracusa 7
Ardabil 6
Den Haag 6
Fukuoka 6
Fuzhou 6
Groningen 6
Melbourne 6
Mountain View 6
Redwood City 6
San Gregorio di Catania 6
Bologna 5
Centro 5
Dearborn 5
Froges 5
Hanoi 5
Heidelberg 5
Lentini 5
Marseille 5
Milan 5
Monmouth Junction 5
Pace 5
Rimini 5
San Francisco 5
Terrassa 5
Abuja 4
Civitavecchia 4
Hyderabad 4
Misterbianco 4
Oslo 4
Paris 4
Singapore 4
Taizhou 4
Tel Aviv 4
Tokyo 4
Valencia 4
Vittoria 4
Algiers 3
Amsterdam 3
Benevento 3
Camerino 3
Chioggia 3
Edinburgh 3
Florence 3
Frankfurt Am Main 3
Frankfurt am Main 3
Totale 6.100
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Nome #
Wilms' tumor gene 1 silencing inhibits proliferation of human osteosarcoma MG-63 cell line by cell cycle arrest and apoptosis activation. 395
Simultaneous targeting of MOR/DOR: A useful strategy for inflammatory pain modulation 353
NOP RECEPTOR ANTAGONISM IN THE VENTROLATERAL PERIAQUEDUCTAL GRAY ATTENUATES THE DEVELOPMENT OF OPIOID TOLERANCE. 281
((2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist 172
Involvement of sigma 2 receptor on motor disorder 121
Neuroprotective effects of Rosmarinus officinalis L. extract in oxygen glucose deprivation (OGD)-injured human neural-like cells 99
Influenza del N-sostituente della (–)-cis-N-Normetazocina nella modulazione del profilo funzionale al MOR, DOR e KOR: da agonista ad antagonista attraverso ligandi misti agonisti/antagonisti 98
Studio aerobiologico e incidenza di pollinosi nella popolazione acese 78
Exploiting the Power of Stereochemistry in Drug Action: 3-[(2S,6S,11S)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide as Potent Sigma-1 Receptor Antagonist 78
Design, synthesis, in vitro evaluation, and molecular modeling studies of N-substituted benzomorphans, analogs of LP2, as novel MOR ligands 73
Inhibition of Cx43 mediates protective effects on hypoxic/reoxygenated human neuroblastoma cells 73
LP2 e 2S-LP2: agonisti biased dual target MOR/DOR nel trattamento del dolore cronico 72
R- ed S-LP2: sintesi, molecular docking e valutazione farmacologica 67
Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis 67
Sigma-2 receptor ligands QSAR model dataset 65
Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists 65
In Vitro Antioxidant Activity and In Vivo Topical Efficacy of Lipid Nanoparticles Co-Loading Idebenone and Tocopheryl Acetate 64
Intercellular communication and ion channels in neuropathic pain chronicization 61
Effect of CCK-8 on analgesia induced by cold-restraint stress in the rat 60
Development of novel LP1-based analogues with enhanced delta opioid receptor profile 60
Connexins in the central nervous system: physiological traits and neuroprotective targets 60
Benzomorphan skeleton, a versatile scaffold for different targets: A comprehensive review 60
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands 60
CHF5074 protects SH-SY5Y human neuronal-like cells from amyloidbeta 25-35 and tumor necrosis factor related apoptosis inducing ligand toxicity in vitro 58
The benzomorphan-based LP1 ligand is a suitable MOR/DOR agonist for chronic pain treatment 58
Central and peripheral control by endogenous opioid peptides of gastric protection in stressed-rats 57
Chronic treatment with fluoxetine induces sex-dependent analgesic effects and modulates HDAC2 and mGlu2 expression in female mice 55
Antinociceptive profile of LP1, a non-peptide multitarget opioid ligand. 54
(+)-and (−)-Phenazocine enantiomers: evaluation of their dual opioid agonist/σ1 antagonist properties and antinociceptive effects 53
MOR/DOR targeting: an useful strategy in pain management 53
Novel Sigma-1 receptor antagonists: From opioids to small molecules: What is new? 53
Wilms' tumor 1 (WT1) protein expression in human developing tissues 52
Effects of dinorphin 1-13 on hyperalgesia induced by interleukin-1bera in the rat 51
Ischemic tolerance modulates TRAIL expression and its receptors and generates a neuroprotected phenotype 51
2. Wilms’ Tumor Gene 1 (WT1) silencing inhibits proliferation of malignant peripheral nerve sheath tumor sNF96.2 cell line 51
Dual MOR/DOR agonist benzomorphan-based compounds for pain relief 51
Synthesis and pharmacological evaluation of novel series of (+)-MR200 derivatives 51
In vitro and in vivo pharmacological evaluation of LP1, a benzomorphan-based compound 50
Repeated activation of delta opiod receptors counteracts nerve injury-induced TNF-α up-regulation in the sciatic nerve of rats with neuropathic pain: A possible correlation with delta opiod receptors-mediated antiallodinic effect. 50
Evaluation of N-substituent structural variations in opioid receptor profile of LP1. 50
Effect of supraspinal Nocistatin on nociceptin/OrphaninFQ antagonism of selective opioid analgesia 49
The antagonistic effect of the sigma 1 receptor ligand (+)-MR200 on persistent pain induced by inflammation. 49
THE BENZOMORPHAN-BASED COMPOUND LP1 AS A MULTITARGET OPIOID LIGAND FOR CHRONIC PAIN TREATMENT 49
Stress-induced changes in the thermic effects of cholecystokinin in the rat 48
Multitarget opioid ligands in pain relief: New players in an old game 48
ANTIALLODINIC AND ANTIHYPERALGESIC EFFECTS OF LP1, AN OPIOID MULTITARGET LIGAND, IN INFLAMMATORY AND NEUROPATHIC PAIN STATES 48
Multitarget Opioid/Non-opioid Ligands: A Potential Approach in Pain Management 48
The Benzomorphan-Based Compound LP1 as Suitable Candidate for Pain Management 48
INVOLVEMENT OF ENDOGENOUS OPIOIDS IN THE ANALGESIC EFFECT OF SUBSTANCE P AT SUPRASPINAL LEVEL 47
Role of the Nrf2/HO-1 axis in bronchopulmonary dysplasia and hyperoxic lung injuries 47
Synthesis and Structure-Activity Relationships of LP1 Derivatives: N-Methyl-N-phenylethylamino Analogues as Novel MOR Agonists 47
Activity of profens as racemic (R and S) enantiomers in human condrocytes and cartilage 46
The Multimodal MOPr/DOPr Agonist LP2 Reduces Allodynia in Chronic Constriction Injured Rats by Rescue of TGF-β1 Signalling 46
Inhibition of pain response in the formalin test by naloxone in normal- or cold-.restrained-rats 45
The blockade of NOP receptor in the vlPAG reduces the development of tolerance to opioid-induced antinociception in rats 45
Neuroprotective effect of the new sigma receptor ligands cis-(+) and cis-(–)-PPCC 45
Apoptotic effects of (±) MRJF4 in prostate cancer cells 45
Effects of a Selective Sigma 1 Antagonist Compound on Inflammatory Pain 45
Involvement of the Heme-Oxygenase Pathway in the Antiallodynic and Antihyperalgesic Activity of Harpagophytum procumbens in Rats. 44
Activity of profens as racemic (R and S) enantiomers in human condrocytes and cartilage 44
Rosemary Essential Oil-Loaded Lipid Nanoparticles: In Vivo Topical Activity from Gel Vehicles 44
Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review 44
MOR/DOR targeting: an useful strategy in pain management 44
Harpagophytum procumbens extract potentiates morphine antinociception in neuropathic rats. 44
Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain 44
Prevention of stress-induced gastric ulcers by m- and d-opioid agonists in the rat 43
HDAC and HAT inhibitors differently affect analgesia mediated by group II metabotropic glutamate receptors 43
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives 43
Preclinical evidence of enhanced analgesic activity of duloxetine complexed with succinyl-β-cyclodextrin: A comparative study with cyclodextrin complexes 43
ANTIALLODYNIC AND ANTIHYPERALGESIC EFFECTS OF INTRAPLANTAR NOCISTATIN AND (±)-J 113397 IN INFLAMMATORY PAIN 42
Blockade of the nociceptin/orphanin FQ/NOP receptor system in the rat ventrolateral periaqueductal gray potentiates DAMGO analgesia 42
Lipid Nanoparticle Inclusion Prevents Capsaicin-Induced TRPV1 Defunctionalization 42
Evidence for an interaction between CCK-8 and β-endorphin on body temperature 41
Involvement of the Nociceptin/Orphanin FQ-NOP receptor system in the ventrolateral periaqueductal gray following mechanical allodynia in chronic pain 41
Opioid and sigma receptor studies. New developments in the design of selective sigma ligands 41
The multitarget opioid ligand LP1's effects in persistent pain and in primary cell neuronal cultures 41
Progress in the development of more effective and safer analgesics for pain management 41
Eliminazione delle sostanze tossiche 40
An LP1 analogue, selective MOR agonist with a peculiar pharmacological profile, used to scrutiny the ligand binding domain 40
In-vitro evaluation of a new benzomorphan-based ligand 40
Synthesis and in vitro opioid receptor studies on benzomorphan-based compounds: LP1, a potent and long-acting antinociceptive 40
Phenytoin differentially modulates the affinity of sigma1 receptor ligands: studies with newly synthesized sigma1 compounds 40
Rescue of noradrenergic system as a novel pharmacological strategy in the treatment of chronic pain: Focus on microglia activation 40
effetti dell'orfaninaFQ sull'analgesia da oppioidi nel ratto 39
In vitro evaluation of new benzomorphan-based ligands 39
Antiallodynic and antihyperalgesic effects of intraplantar nocistatin and (+/-)-J113397 in inflammatory pain 39
Involvement of prostaglandins on morphine-induced gastric protection in rats 39
FARMACODINAMICA DEGLI ENANTIOMERI (S),(R),DEL FLURBIPROFENE E KETOPROFENE IN COLTURE DI CARTILAGINE UMANA E CONDROCITI 39
A new Sigma-1 Receptor antagonist in Chronic Pain Treatment: (+)-2R/S-LP2 effects in inflammatory and neuropathic pain 38
Modification of CCK-8 hypothermia after chronic administration of dexamethasone in the rat 38
Design and synthesis of new bifunctional sigma-1 selective ligands with antioxidant activity. 38
Pain management: new long-acting opioid ligands 38
Different in vitro activity of flurbiprofen and its enantimers on human articular cartilage 38
Supraspinal injection of Substance P attenuates allodynia and hyperalgesia in a rat model of inflammatory pain 37
New bifunctional antioxidant/σ1 agonist ligands: preliminary chemico-physical and biological evaluation 37
metabolismo delle sostanze tossiche 37
Antiallodinic and antihyperalgesic effects of LP1, an opioid multitarget ligand, in inflammatory and neurophatic pain states 37
Synthesis and structure-activity relationships of (–)-cis-N-normetazocine-based LP1 derivatives 37
Tossicità epatica 36
New " Receptor Ligands with Neuroprotective Effect: Synthesis and Resolution of cis-(±)-Methyl (1R,2S/1S,2R)-2-[(4-Hydroxy-4- phenylpiperidin-1-yl)methyl]-1-(4- methylphenyl)cyclopropanecarboxylate [(±)-PPCC] 36
Totale 6.018
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Categoria #
all - tutte 24.613
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.613
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019280 0 0 0 0 0 0 0 0 0 6 43 231
2019/20201.771 465 134 185 245 281 48 87 12 91 57 115 51
2020/20211.097 16 94 118 34 301 35 108 8 115 18 177 73
2021/20221.418 166 184 16 38 215 16 191 58 126 23 57 328
2022/20232.490 201 129 47 297 224 387 8 458 527 45 103 64
2023/2024981 83 227 78 63 71 292 57 76 2 32 0 0
Totale 8.549